DK1263978T3 - Hybridpromotorer som kan induceres af inflammation, vektorer indeholdende disse og anvendelse deraf - Google Patents
Hybridpromotorer som kan induceres af inflammation, vektorer indeholdende disse og anvendelse derafInfo
- Publication number
- DK1263978T3 DK1263978T3 DK01914000T DK01914000T DK1263978T3 DK 1263978 T3 DK1263978 T3 DK 1263978T3 DK 01914000 T DK01914000 T DK 01914000T DK 01914000 T DK01914000 T DK 01914000T DK 1263978 T3 DK1263978 T3 DK 1263978T3
- Authority
- DK
- Denmark
- Prior art keywords
- inflammation
- induced
- vectors containing
- hybrid promoters
- vivo
- Prior art date
Links
- 239000013598 vector Substances 0.000 title abstract 2
- 206010061218 Inflammation Diseases 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- 230000014509 gene expression Effects 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000001105 regulatory effect Effects 0.000 abstract 2
- 102000003728 Peroxisome Proliferator-Activated Receptors Human genes 0.000 abstract 1
- 108090000029 Peroxisome Proliferator-Activated Receptors Proteins 0.000 abstract 1
- 108700019146 Transgenes Proteins 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000004968 inflammatory condition Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 230000035897 transcription Effects 0.000 abstract 1
- 238000013518 transcription Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
- C12N9/20—Triglyceride splitting, e.g. by means of lipase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Cell Biology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0003262A FR2806418B1 (fr) | 2000-03-14 | 2000-03-14 | Promoteurs hybrides inductibles par l'inflammation, vecteurs les contenant et utilisations |
| US19695900P | 2000-04-13 | 2000-04-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1263978T3 true DK1263978T3 (da) | 2006-04-18 |
Family
ID=26212255
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01914000T DK1263978T3 (da) | 2000-03-14 | 2001-03-14 | Hybridpromotorer som kan induceres af inflammation, vektorer indeholdende disse og anvendelse deraf |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1263978B1 (da) |
| JP (1) | JP2003526368A (da) |
| AT (1) | ATE312187T1 (da) |
| AU (1) | AU2001239392A1 (da) |
| CA (1) | CA2403189A1 (da) |
| DE (1) | DE60115610T2 (da) |
| DK (1) | DK1263978T3 (da) |
| ES (1) | ES2254378T3 (da) |
| WO (1) | WO2001068845A2 (da) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2269897A (en) * | 1992-08-13 | 1994-02-23 | Merck Frosst Canada Inc | Assay to detect peroxisome proliferator activity |
| FR2755699B1 (fr) * | 1996-11-08 | 1998-12-18 | Rhone Poulenc Rorer Sa | Nouvelles constructions et vecteurs pour l'expression ciblee et inductible des genes |
| US5925657A (en) * | 1997-06-18 | 1999-07-20 | The General Hospital Corporation | Use of PPARγ agonists for inhibition of inflammatory cytokine production |
| CN1370240A (zh) * | 1999-06-22 | 2002-09-18 | 阿文蒂斯药物股份有限公司 | 利用ppar核受体的表达调节系统 |
-
2001
- 2001-03-14 DE DE60115610T patent/DE60115610T2/de not_active Expired - Lifetime
- 2001-03-14 DK DK01914000T patent/DK1263978T3/da active
- 2001-03-14 WO PCT/FR2001/000759 patent/WO2001068845A2/fr active IP Right Grant
- 2001-03-14 EP EP01914000A patent/EP1263978B1/fr not_active Expired - Lifetime
- 2001-03-14 CA CA002403189A patent/CA2403189A1/fr not_active Abandoned
- 2001-03-14 AT AT01914000T patent/ATE312187T1/de not_active IP Right Cessation
- 2001-03-14 ES ES01914000T patent/ES2254378T3/es not_active Expired - Lifetime
- 2001-03-14 JP JP2001567329A patent/JP2003526368A/ja active Pending
- 2001-03-14 AU AU2001239392A patent/AU2001239392A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1263978B1 (fr) | 2005-12-07 |
| EP1263978A2 (fr) | 2002-12-11 |
| ATE312187T1 (de) | 2005-12-15 |
| DE60115610D1 (de) | 2006-01-12 |
| DE60115610T2 (de) | 2006-10-19 |
| AU2001239392A1 (en) | 2001-09-24 |
| WO2001068845A2 (fr) | 2001-09-20 |
| ES2254378T3 (es) | 2006-06-16 |
| JP2003526368A (ja) | 2003-09-09 |
| CA2403189A1 (fr) | 2001-09-20 |
| WO2001068845A3 (fr) | 2002-02-28 |
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