DK1259507T3 - Pseudopolymorf af (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8[4R-(3S-hydroxy-1-methyl)piperidinyl]-4H-1-benzopyran-4-on, hydrochlorid - Google Patents

Pseudopolymorf af (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8[4R-(3S-hydroxy-1-methyl)piperidinyl]-4H-1-benzopyran-4-on, hydrochlorid

Info

Publication number
DK1259507T3
DK1259507T3 DK01900939T DK01900939T DK1259507T3 DK 1259507 T3 DK1259507 T3 DK 1259507T3 DK 01900939 T DK01900939 T DK 01900939T DK 01900939 T DK01900939 T DK 01900939T DK 1259507 T3 DK1259507 T3 DK 1259507T3
Authority
DK
Denmark
Prior art keywords
pseudopolymorph
benzopyran
piperidinyl
chlorophenyl
dihydroxy
Prior art date
Application number
DK01900939T
Other languages
Danish (da)
English (en)
Inventor
Gary L Bafus
Christine M Harrison-Bowman
Gary L Silvey
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Application granted granted Critical
Publication of DK1259507T3 publication Critical patent/DK1259507T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Stereophonic System (AREA)
  • Inorganic Insulating Materials (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrane Compounds (AREA)
DK01900939T 2000-01-18 2001-01-08 Pseudopolymorf af (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8[4R-(3S-hydroxy-1-methyl)piperidinyl]-4H-1-benzopyran-4-on, hydrochlorid DK1259507T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48471700A 2000-01-18 2000-01-18
EP01900939A EP1259507B1 (en) 2000-01-18 2001-01-08 Pseudopolymorph of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8 4r-(3s-hydroxy-1-methyl)piperidinyl]-4h-1-benzopyran-4-one hydrochloride
PCT/US2001/000519 WO2001053293A1 (en) 2000-01-18 2001-01-08 Pseudopolymorph of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8[4r-(3s-hydroxy-1-methyl)piperidinyl]-4h-1-benzopyran-4-one

Publications (1)

Publication Number Publication Date
DK1259507T3 true DK1259507T3 (da) 2004-11-01

Family

ID=23925305

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01900939T DK1259507T3 (da) 2000-01-18 2001-01-08 Pseudopolymorf af (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8[4R-(3S-hydroxy-1-methyl)piperidinyl]-4H-1-benzopyran-4-on, hydrochlorid

Country Status (26)

Country Link
EP (1) EP1259507B1 (hu)
JP (1) JP2003520797A (hu)
KR (1) KR100806464B1 (hu)
CN (1) CN1174977C (hu)
AT (1) ATE273303T1 (hu)
AU (1) AU2001226346A1 (hu)
BR (1) BR0107726A (hu)
CA (1) CA2397593C (hu)
CZ (1) CZ301195B6 (hu)
DE (1) DE60104822T2 (hu)
DK (1) DK1259507T3 (hu)
EA (1) EA005247B1 (hu)
ES (1) ES2222332T3 (hu)
HU (1) HUP0204126A3 (hu)
IL (2) IL150638A0 (hu)
MX (1) MXPA02007005A (hu)
NO (1) NO322572B1 (hu)
NZ (1) NZ520280A (hu)
PL (1) PL200696B1 (hu)
PT (1) PT1259507E (hu)
SI (1) SI1259507T1 (hu)
SK (1) SK287404B6 (hu)
TR (1) TR200402036T4 (hu)
TW (1) TWI284129B (hu)
WO (1) WO2001053293A1 (hu)
ZA (1) ZA200205639B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190175598A1 (en) 2016-08-23 2019-06-13 Eisai R&D Management Co., Ltd. Combination therapies for the treatment of hepatocellular carcinoma
MX2019010981A (es) 2017-03-16 2020-09-07 Eisai R&D Man Co Ltd Terapias de combinacion para el tratamiento de cancer de mama.
AU2019407426A1 (en) 2018-12-21 2021-07-22 Daiichi Sankyo Company, Limited Combination of antibody-drug conjugate and kinase inhibitor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN164232B (hu) * 1986-04-11 1989-02-04 Hoechst India
US5284856A (en) * 1988-10-28 1994-02-08 Hoechst Aktiengesellschaft Oncogene-encoded kinases inhibition using 4-H-1-benzopyran-4-one derivatives
US5908934A (en) * 1996-09-26 1999-06-01 Bristol-Myers Squibb Company Process for the preparation of chiral ketone intermediates useful for the preparation of flavopiridol and analogs

Also Published As

Publication number Publication date
HUP0204126A2 (hu) 2003-04-28
DE60104822D1 (de) 2004-09-16
HUP0204126A3 (en) 2006-02-28
AU2001226346A1 (en) 2001-07-31
SI1259507T1 (en) 2005-02-28
WO2001053293A1 (en) 2001-07-26
EA200200775A1 (ru) 2002-12-26
NO20023386L (no) 2002-09-12
NO20023386D0 (no) 2002-07-12
EA005247B1 (ru) 2004-12-30
SK287404B6 (sk) 2010-09-07
SK10362002A3 (sk) 2003-01-09
EP1259507B1 (en) 2004-08-11
JP2003520797A (ja) 2003-07-08
ES2222332T3 (es) 2005-02-01
IL150638A (en) 2009-06-15
IL150638A0 (en) 2003-02-12
MXPA02007005A (es) 2004-09-06
CN1174977C (zh) 2004-11-10
ZA200205639B (en) 2003-10-15
TR200402036T4 (tr) 2004-10-21
CA2397593A1 (en) 2001-07-26
DE60104822T2 (de) 2005-09-01
CZ301195B6 (cs) 2009-12-02
PL356165A1 (en) 2004-06-14
KR100806464B1 (ko) 2008-02-21
ATE273303T1 (de) 2004-08-15
CA2397593C (en) 2009-11-10
KR20020069361A (ko) 2002-08-30
CN1395576A (zh) 2003-02-05
PT1259507E (pt) 2004-12-31
PL200696B1 (pl) 2009-01-30
BR0107726A (pt) 2002-10-01
CZ20022466A3 (cs) 2002-11-13
NO322572B1 (no) 2006-10-30
EP1259507A1 (en) 2002-11-27
NZ520280A (en) 2004-04-30
TWI284129B (en) 2007-07-21

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