DK125247B - Fremgangsmåde til fremstilling af 9-(β-D-arabinofuranosyl)-adenin-5'-phospat eller salte heraf. - Google Patents

Fremgangsmåde til fremstilling af 9-(β-D-arabinofuranosyl)-adenin-5'-phospat eller salte heraf.

Info

Publication number
DK125247B
DK125247B DK492470AA DK492470A DK125247B DK 125247 B DK125247 B DK 125247B DK 492470A A DK492470A A DK 492470AA DK 492470 A DK492470 A DK 492470A DK 125247 B DK125247 B DK 125247B
Authority
DK
Denmark
Prior art keywords
arabinofuranosyl
adenine
phosphate
salts
preparation
Prior art date
Application number
DK492470AA
Other languages
Danish (da)
English (en)
Inventor
T Haskell
D Watson
Original Assignee
Parke Davis & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25335938&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK125247(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Parke Davis & Co filed Critical Parke Davis & Co
Publication of DK125247B publication Critical patent/DK125247B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK492470AA 1969-09-26 1970-09-25 Fremgangsmåde til fremstilling af 9-(β-D-arabinofuranosyl)-adenin-5'-phospat eller salte heraf. DK125247B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86148569A 1969-09-26 1969-09-26

Publications (1)

Publication Number Publication Date
DK125247B true DK125247B (da) 1973-01-22

Family

ID=25335938

Family Applications (1)

Application Number Title Priority Date Filing Date
DK492470AA DK125247B (da) 1969-09-26 1970-09-25 Fremgangsmåde til fremstilling af 9-(β-D-arabinofuranosyl)-adenin-5'-phospat eller salte heraf.

Country Status (13)

Country Link
US (1) US3703507A (xx)
JP (1) JPS514999B1 (xx)
BE (1) BE756704A (xx)
CA (1) CA924712A (xx)
CH (1) CH514627A (xx)
DE (1) DE2047368A1 (xx)
DK (1) DK125247B (xx)
ES (1) ES383982A1 (xx)
FR (1) FR2062638A5 (xx)
GB (1) GB1291757A (xx)
NL (1) NL7014188A (xx)
SE (1) SE374922B (xx)
ZA (1) ZA706557B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038479A (en) * 1969-11-17 1977-07-26 Burroughs Wellcome Co. Amino purine derivatives
FR2206087A1 (en) * 1972-11-13 1974-06-07 Icn Pharmaceuticals 9-beta-d-arabinofuranosyl-adenine 3',5'-cyclo monophosphate - - antiviral cpd,and its intermediates
US3919194A (en) * 1972-12-26 1975-11-11 Kohjin Co S-substituted 2-thioadenosine-5{40 -monophosphates and process for producing the same
JPS5046696A (xx) * 1973-03-19 1975-04-25
US3923785A (en) * 1974-04-22 1975-12-02 Parke Davis & Co (R)-3-(2-deoxy-{62 -D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo{8 4,5-d{9 {8 1,3{9 diazepin-8-ol
GB1562899A (en) * 1975-06-17 1980-03-19 Wellcome Found Pharmaceutical compositions containing substituted 9-( -d-arabnofuranosyl)purine-5'-phosphate and salts thereof
AT358187B (de) * 1976-11-03 1980-08-25 Parke Davis & Co Verfahren zur herstellung von 9-(beta-d- -arabinofuranosyl)-adenin-5'-phosphat
EP0015584A3 (de) * 1979-03-12 1980-12-10 Kailash Kumar Dr. Prof. Gauri Neue Nukleotide, Verfahren zu ihrer Herstellung und Arzneimittel
US4315000A (en) * 1980-07-07 1982-02-09 Warner-Lambert Company β-D-Arabinofuranosylimidazo(4,5-c)pyridine compounds and methods for their production
US4352795A (en) * 1981-01-29 1982-10-05 Warner-Lambert Company 7-β-D-Arabinofuranosyl-7H-pyrrolo[2,3-d]pyrimidine compounds and methods for their production
US4357324A (en) * 1981-02-24 1982-11-02 The United States Of America As Represented By The Department Of Health And Human Services Prodrug derivatives of 9β-D-arabinofuranosyl-2-fluoroadenine
FR2701027B1 (fr) * 1993-02-01 1997-07-18 Warner Lambert Co Procede de synthese ameliore du 9-(beta-d-arabinofuranosyl)adenine 5'-phosphate.
EP1047704B2 (de) 1997-12-11 2007-11-07 Bayer Schering Pharma Aktiengesellschaft Verfahren zur herstellung von fludarabin-phosphat-lithium-, natrium-, kalium-, calcium- und magnesium-salzen, reinigungsverfahren zur herstellung von fludarabin-phosphat und fludarabin-phosphat mit mindestens 99,5 %iger reinheit
ITMI20011361A1 (it) * 2001-06-28 2002-12-28 Enichem Spa Metodo di purificazione della cicloesanossima
US20070167353A1 (en) * 2003-10-24 2007-07-19 John Hilfinger Prodrug composition
CN103204890B (zh) * 2013-02-22 2016-03-09 广东先强药业有限公司 一种磷酸化法制备单磷酸阿糖腺苷的方法
CN107098943A (zh) * 2017-06-07 2017-08-29 广东隆赋药业股份有限公司 一种高纯度单磷酸阿糖腺苷的制备方法

Also Published As

Publication number Publication date
CA924712A (en) 1973-04-17
JPS514999B1 (xx) 1976-02-16
NL7014188A (xx) 1971-03-30
ZA706557B (en) 1972-04-26
BE756704A (fr) 1971-03-01
SE374922B (xx) 1975-03-24
GB1291757A (en) 1972-10-04
FR2062638A5 (xx) 1971-06-25
ES383982A1 (es) 1973-03-01
US3703507A (en) 1972-11-21
CH514627A (fr) 1971-10-31
DE2047368A1 (de) 1971-04-01

Similar Documents

Publication Publication Date Title
DK138795B (da) Analogifremgangsmåde til fremstilling af N-benzylimidazolderivater eller salte deraf.
DK139869B (da) Analogifremgangsmåde til fremstilling af phenyl-imidazolyl-alkansyrederivater eller salte deraf.
DK134113B (da) Analogifremgangsmåde til fremstilling af 1,2,3,4-tetrahydro-7-halogen-eller 7-trifluormethyl-6-sulfamyl-4-quinazolinoner eller salte heraf.
DK132172B (da) Analogifremgangsmåde til fremstilling af 6,7-benzomorphaner eller salte deraf.
DK125247B (da) Fremgangsmåde til fremstilling af 9-(β-D-arabinofuranosyl)-adenin-5'-phospat eller salte heraf.
DK128117B (da) Analogifremgangsmåde til fremstilling af 2,6-diamino-9-(β-D-arabinofuranosyl)-purin.
DK126788B (da) Analogifremgangsmåde til fremstilling af γ-morpholino-p-amino-butyrophenoner eller salte deraf.
DK129650B (da) Analogifremgangsmåde til fremstilling af 1-phenoxy-2-hydroxy-3-amino-propaner eller salte deraf.
DK135534B (da) Fremgangsmåde til fremstilling af pyrasol-(3,4-d)-pyrimidiner eller salte heraf.
DK123708B (da) Fremgangsmåde til fremstilling af polyencarboxylsyrer eller salte deraf.
DK125245B (da) Fremgangsmåde til fremstilling af γpiperidinobutyrophenonderivater eller syreadditionssalte deraf.
DK138015B (da) Fremgangsmåde til fremstilling af substituerede N-cycloalkyl-arylamino-imidazoliner-(2) eller syreadditionssalte deraf.
DK127424B (da) Analogifremgangsmåde til fremstilling af 4-aryl-1-(4,4-diarylbutyl)-4-hydroxypiperidiner eller syreadditionssalte deraf.
DK131374B (da) Fremgangsmåde til fremstilling af 1,4-benzodiazepinderivater eller salte deraf.
DK139973B (da) Analogifremgangsmåde til fremstilling af s-triazolo-(4,3-a)(1,4)-benzodiazepinderivater eller syreadditionssalte deraf.
DK133778B (da) Analogifremgangsmåde til fremstilling af substituerede isoquinoliner eller salte heraf.
DK127432B (da) Analogifremgangsmåde til fremstilling af acylaminopenicillansyrer eller salte deraf.
DK130833B (da) Analogifremgangsmåde til fremstilling af N(6)-disubstituerede adenosinderivater.
DK124035B (da) Fremgangsmåde til fremstilling af α-carboxybenzylpencillin eller salte deraf.
DK134557B (da) Analogifremgangsmåde til fremstilling af estere af alfa-amino-aryl-eller thienylmetylpenicilliner eller salte heraf.
DK126201B (da) Analogifremgangsmåde til fremstilling af 1,4-benzodiazepinderivater eller salte deraf.
DK136364B (da) Analogifremgangsmåde til fremstilling af 4(5)-trifluormethylimidazolderivater eller salte deraf.
DK140256B (da) Analogifremgangsmåde til fremstilling af 2-alkyl-5-thiazolcarboxylsyrer eller salte deraf.
DK124885B (da) Analogifremgangsmåde til fremstilling af 4-alkenyl-substituerede 1,2-difenyl-3,5-dioxopyrazolidiner eller salte heraf.
DK120796B (da) Analogifremgangsmåde til fremstilling af 1,2-oxazinderivater eller salte deraf.

Legal Events

Date Code Title Description
PUP Patent expired