BE756704A - Procede de production du 5'-phosphate de 9-(beta-d- arabinofuranosyl) adenine et de ses sels - Google Patents

Procede de production du 5'-phosphate de 9-(beta-d- arabinofuranosyl) adenine et de ses sels

Info

Publication number
BE756704A
BE756704A BE756704DA BE756704A BE 756704 A BE756704 A BE 756704A BE 756704D A BE756704D A BE 756704DA BE 756704 A BE756704 A BE 756704A
Authority
BE
Belgium
Prior art keywords
arabinofuranosyl
adenine
beta
phosphate
salts
Prior art date
Application number
Other languages
English (en)
Inventor
T H Haskell
D R Watson
Original Assignee
Parke Davis & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25335938&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BE756704(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Publication of BE756704A publication Critical patent/BE756704A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE756704D 1969-09-26 Procede de production du 5'-phosphate de 9-(beta-d- arabinofuranosyl) adenine et de ses sels BE756704A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86148569A 1969-09-26 1969-09-26

Publications (1)

Publication Number Publication Date
BE756704A true BE756704A (fr) 1971-03-01

Family

ID=25335938

Family Applications (1)

Application Number Title Priority Date Filing Date
BE756704D BE756704A (fr) 1969-09-26 Procede de production du 5'-phosphate de 9-(beta-d- arabinofuranosyl) adenine et de ses sels

Country Status (13)

Country Link
US (1) US3703507A (fr)
JP (1) JPS514999B1 (fr)
BE (1) BE756704A (fr)
CA (1) CA924712A (fr)
CH (1) CH514627A (fr)
DE (1) DE2047368A1 (fr)
DK (1) DK125247B (fr)
ES (1) ES383982A1 (fr)
FR (1) FR2062638A5 (fr)
GB (1) GB1291757A (fr)
NL (1) NL7014188A (fr)
SE (1) SE374922B (fr)
ZA (1) ZA706557B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038479A (en) * 1969-11-17 1977-07-26 Burroughs Wellcome Co. Amino purine derivatives
FR2206087A1 (en) * 1972-11-13 1974-06-07 Icn Pharmaceuticals 9-beta-d-arabinofuranosyl-adenine 3',5'-cyclo monophosphate - - antiviral cpd,and its intermediates
US3919194A (en) * 1972-12-26 1975-11-11 Kohjin Co S-substituted 2-thioadenosine-5{40 -monophosphates and process for producing the same
CA1023355A (en) * 1973-03-19 1977-12-27 Icn Pharmaceuticals 9-.beta.-D-ARABINOFURANOSYL PURINE NUCLEOTIDES
US3923785A (en) * 1974-04-22 1975-12-02 Parke Davis & Co (R)-3-(2-deoxy-{62 -D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo{8 4,5-d{9 {8 1,3{9 diazepin-8-ol
GB1562899A (en) * 1975-06-17 1980-03-19 Wellcome Found Pharmaceutical compositions containing substituted 9-( -d-arabnofuranosyl)purine-5'-phosphate and salts thereof
DE2749056A1 (de) * 1976-11-03 1978-05-18 Parke Davis & Co Verfahren zur herstellung von 9-(beta-d-arabinofuranosyl)-adenin- 5'-phosphat
EP0015584A3 (fr) * 1979-03-12 1980-12-10 Kailash Kumar Dr. Prof. Gauri Nucléotides, procédés pour leur préparation et médicaments
US4315000A (en) * 1980-07-07 1982-02-09 Warner-Lambert Company β-D-Arabinofuranosylimidazo(4,5-c)pyridine compounds and methods for their production
US4352795A (en) * 1981-01-29 1982-10-05 Warner-Lambert Company 7-β-D-Arabinofuranosyl-7H-pyrrolo[2,3-d]pyrimidine compounds and methods for their production
US4357324A (en) * 1981-02-24 1982-11-02 The United States Of America As Represented By The Department Of Health And Human Services Prodrug derivatives of 9β-D-arabinofuranosyl-2-fluoroadenine
FR2701027B1 (fr) * 1993-02-01 1997-07-18 Warner Lambert Co Procede de synthese ameliore du 9-(beta-d-arabinofuranosyl)adenine 5'-phosphate.
DE59807096D1 (de) 1997-12-11 2003-03-06 Schering Ag Verfahren zur herstellung von fludarabin-phosphat-lithium-, natrium-, kalium-, calcium- und magnesium-salzen, reinigungsverfahren zur herstellung von fludarabin-phosphat und fludarabin-phosphat mit mindestens 99,5 %iger reinheit
ITMI20011361A1 (it) * 2001-06-28 2002-12-28 Enichem Spa Metodo di purificazione della cicloesanossima
US20070167353A1 (en) * 2003-10-24 2007-07-19 John Hilfinger Prodrug composition
CN103204890B (zh) * 2013-02-22 2016-03-09 广东先强药业有限公司 一种磷酸化法制备单磷酸阿糖腺苷的方法
CN107098943A (zh) * 2017-06-07 2017-08-29 广东隆赋药业股份有限公司 一种高纯度单磷酸阿糖腺苷的制备方法

Also Published As

Publication number Publication date
ES383982A1 (es) 1973-03-01
DK125247B (da) 1973-01-22
DE2047368A1 (de) 1971-04-01
JPS514999B1 (fr) 1976-02-16
FR2062638A5 (fr) 1971-06-25
US3703507A (en) 1972-11-21
SE374922B (fr) 1975-03-24
CA924712A (en) 1973-04-17
ZA706557B (en) 1972-04-26
NL7014188A (fr) 1971-03-30
CH514627A (fr) 1971-10-31
GB1291757A (en) 1972-10-04

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: PARKE DAVIS & CY

Effective date: 19900925