CH514627A - Procédé de préparation du 5'-phosphate de 9-(B-D-arabinofuranosyl)adénine et de ses sels - Google Patents

Procédé de préparation du 5'-phosphate de 9-(B-D-arabinofuranosyl)adénine et de ses sels

Info

Publication number
CH514627A
CH514627A CH1419170A CH1419170A CH514627A CH 514627 A CH514627 A CH 514627A CH 1419170 A CH1419170 A CH 1419170A CH 1419170 A CH1419170 A CH 1419170A CH 514627 A CH514627 A CH 514627A
Authority
CH
Switzerland
Prior art keywords
arabinofuranosyl
adenine
phosphate
salts
preparation
Prior art date
Application number
CH1419170A
Other languages
English (en)
Inventor
Ann Arbor Theodore Her Haskell
Richard Watson Donals
Original Assignee
Parke Davis & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25335938&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CH514627(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Parke Davis & Co filed Critical Parke Davis & Co
Publication of CH514627A publication Critical patent/CH514627A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1419170A 1969-09-26 1970-09-25 Procédé de préparation du 5'-phosphate de 9-(B-D-arabinofuranosyl)adénine et de ses sels CH514627A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86148569A 1969-09-26 1969-09-26

Publications (1)

Publication Number Publication Date
CH514627A true CH514627A (fr) 1971-10-31

Family

ID=25335938

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1419170A CH514627A (fr) 1969-09-26 1970-09-25 Procédé de préparation du 5'-phosphate de 9-(B-D-arabinofuranosyl)adénine et de ses sels

Country Status (13)

Country Link
US (1) US3703507A (fr)
JP (1) JPS514999B1 (fr)
BE (1) BE756704A (fr)
CA (1) CA924712A (fr)
CH (1) CH514627A (fr)
DE (1) DE2047368A1 (fr)
DK (1) DK125247B (fr)
ES (1) ES383982A1 (fr)
FR (1) FR2062638A5 (fr)
GB (1) GB1291757A (fr)
NL (1) NL7014188A (fr)
SE (1) SE374922B (fr)
ZA (1) ZA706557B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038479A (en) * 1969-11-17 1977-07-26 Burroughs Wellcome Co. Amino purine derivatives
FR2206087A1 (en) * 1972-11-13 1974-06-07 Icn Pharmaceuticals 9-beta-d-arabinofuranosyl-adenine 3',5'-cyclo monophosphate - - antiviral cpd,and its intermediates
US3919194A (en) * 1972-12-26 1975-11-11 Kohjin Co S-substituted 2-thioadenosine-5{40 -monophosphates and process for producing the same
IE39184B1 (en) * 1973-03-19 1978-08-16 Icn Pharmaceuticals 9- -d-arabinofuranosyl hypoxanthine nucleotides
US3923785A (en) * 1974-04-22 1975-12-02 Parke Davis & Co (R)-3-(2-deoxy-{62 -D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo{8 4,5-d{9 {8 1,3{9 diazepin-8-ol
GB1562899A (en) * 1975-06-17 1980-03-19 Wellcome Found Pharmaceutical compositions containing substituted 9-( -d-arabnofuranosyl)purine-5'-phosphate and salts thereof
FR2370057A1 (fr) * 1976-11-03 1978-06-02 Parke Davis & Co Procede de production de 9-(b-d-arabinofuranosyl)-adenine, 5'-phosphate
EP0015584A3 (fr) * 1979-03-12 1980-12-10 Kailash Kumar Dr. Prof. Gauri Nucléotides, procédés pour leur préparation et médicaments
US4315000A (en) * 1980-07-07 1982-02-09 Warner-Lambert Company β-D-Arabinofuranosylimidazo(4,5-c)pyridine compounds and methods for their production
US4352795A (en) * 1981-01-29 1982-10-05 Warner-Lambert Company 7-β-D-Arabinofuranosyl-7H-pyrrolo[2,3-d]pyrimidine compounds and methods for their production
US4357324A (en) * 1981-02-24 1982-11-02 The United States Of America As Represented By The Department Of Health And Human Services Prodrug derivatives of 9β-D-arabinofuranosyl-2-fluoroadenine
FR2701027B1 (fr) * 1993-02-01 1997-07-18 Warner Lambert Co Procede de synthese ameliore du 9-(beta-d-arabinofuranosyl)adenine 5'-phosphate.
SI1047704T2 (sl) 1997-12-11 2008-02-29 Bayer Schering Pharma Ag Postopek za pripravo fludarabin-fosfat litijevih,natrijevih, kalijevih, kalcijevih in magnezijevihsoli, cistilni postopek za pripravo fludarabin-fosfata in fludarabin-fosfat z vsaj 99,5 % cistoto
ITMI20011361A1 (it) * 2001-06-28 2002-12-28 Enichem Spa Metodo di purificazione della cicloesanossima
US20070167353A1 (en) * 2003-10-24 2007-07-19 John Hilfinger Prodrug composition
CN103204890B (zh) * 2013-02-22 2016-03-09 广东先强药业有限公司 一种磷酸化法制备单磷酸阿糖腺苷的方法
CN107098943A (zh) * 2017-06-07 2017-08-29 广东隆赋药业股份有限公司 一种高纯度单磷酸阿糖腺苷的制备方法

Also Published As

Publication number Publication date
FR2062638A5 (fr) 1971-06-25
ZA706557B (en) 1972-04-26
DE2047368A1 (de) 1971-04-01
GB1291757A (en) 1972-10-04
DK125247B (da) 1973-01-22
ES383982A1 (es) 1973-03-01
SE374922B (fr) 1975-03-24
NL7014188A (fr) 1971-03-30
US3703507A (en) 1972-11-21
CA924712A (en) 1973-04-17
JPS514999B1 (fr) 1976-02-16
BE756704A (fr) 1971-03-01

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Legal Events

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