IE39184B1 - 9- -d-arabinofuranosyl hypoxanthine nucleotides - Google Patents

9- -d-arabinofuranosyl hypoxanthine nucleotides

Info

Publication number
IE39184B1
IE39184B1 IE586/74A IE58674A IE39184B1 IE 39184 B1 IE39184 B1 IE 39184B1 IE 586/74 A IE586/74 A IE 586/74A IE 58674 A IE58674 A IE 58674A IE 39184 B1 IE39184 B1 IE 39184B1
Authority
IE
Ireland
Prior art keywords
compounds
nucleotides
beta
salts
metal salts
Prior art date
Application number
IE586/74A
Other versions
IE39184L (en
Original Assignee
Icn Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/451,639 external-priority patent/US4093714A/en
Application filed by Icn Pharmaceuticals filed Critical Icn Pharmaceuticals
Publication of IE39184L publication Critical patent/IE39184L/en
Publication of IE39184B1 publication Critical patent/IE39184B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The 9 beta-D-arabinofuranosylpurine nucleotides of the formula <IMAGE> in which X and Y are defined in Claim 1, are prepared by deaminating corresponding 9 beta-D-arabinofuranosyladenine nucleotides in the presence of glacial acetic acid, water and sodium nitrite. These compounds can be converted into their ammonium, substituted ammonium or physiologically acceptable metal salts, in which case the alkali metal and alkaline earth metal salts are preferred. The said compounds, as well as their salts, can be used in vitro for controlling viruses, but they can also be used as starting compounds for the preparation of compounds which are employed for controlling viruses. [FR2222092A1]
IE586/74A 1973-03-19 1974-03-19 9- -d-arabinofuranosyl hypoxanthine nucleotides IE39184B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34261773A 1973-03-19 1973-03-19
US05/451,639 US4093714A (en) 1974-03-15 1974-03-15 9β-D-Arabinofuranosylpurine nucleotides and method of use

Publications (2)

Publication Number Publication Date
IE39184L IE39184L (en) 1974-09-19
IE39184B1 true IE39184B1 (en) 1978-08-16

Family

ID=26993103

Family Applications (1)

Application Number Title Priority Date Filing Date
IE586/74A IE39184B1 (en) 1973-03-19 1974-03-19 9- -d-arabinofuranosyl hypoxanthine nucleotides

Country Status (7)

Country Link
JP (1) JPS5046696A (en)
CA (1) CA1023355A (en)
CH (1) CH613211A5 (en)
DE (1) DE2413226A1 (en)
FR (1) FR2222092B1 (en)
IE (1) IE39184B1 (en)
IL (1) IL44537A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1562899A (en) * 1975-06-17 1980-03-19 Wellcome Found Pharmaceutical compositions containing substituted 9-( -d-arabnofuranosyl)purine-5'-phosphate and salts thereof
EP0015584A3 (en) * 1979-03-12 1980-12-10 Kailash Kumar Dr. Prof. Gauri Nucleotides, methods for their preparation and medicaments
JPS58225097A (en) * 1982-06-23 1983-12-27 Yamasa Shoyu Co Ltd Nucleoside 5'-alkyl or alkenylphosphate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3300478A (en) * 1965-06-01 1967-01-24 Upjohn Co Arabinofuranosyl 2', 5'-and 3'-5'-dinucleoside phosphates and process therefor
BE756704A (en) * 1969-09-26 1971-03-01 Parke Davis & Co PROCESS FOR THE PRODUCTION OF 5'-PHOSPHATE OF 9- (BETA-D- ARABINOFURANOSYL) ADENINE AND ITS SALTS

Also Published As

Publication number Publication date
AU6684974A (en) 1975-09-25
CH613211A5 (en) 1979-09-14
DE2413226A1 (en) 1974-10-24
FR2222092A1 (en) 1974-10-18
FR2222092B1 (en) 1978-01-13
CA1023355A (en) 1977-12-27
JPS5046696A (en) 1975-04-25
IL44537A0 (en) 1974-12-31
IE39184L (en) 1974-09-19
IL44537A (en) 1977-05-31

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