DK1246813T3 - Fremgangsmåde til fremstilling af Citalopram - Google Patents

Fremgangsmåde til fremstilling af Citalopram

Info

Publication number
DK1246813T3
DK1246813T3 DK99962133T DK99962133T DK1246813T3 DK 1246813 T3 DK1246813 T3 DK 1246813T3 DK 99962133 T DK99962133 T DK 99962133T DK 99962133 T DK99962133 T DK 99962133T DK 1246813 T3 DK1246813 T3 DK 1246813T3
Authority
DK
Denmark
Prior art keywords
preparing citalopram
citalopram
preparation
preparing
phtalid
Prior art date
Application number
DK99962133T
Other languages
Danish (da)
English (en)
Inventor
Hans Petersen
Michael Harold Rock
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of DK1246813T3 publication Critical patent/DK1246813T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/44Palladium
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/70Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper
    • B01J23/74Iron group metals
    • B01J23/755Nickel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
DK99962133T 1999-12-30 1999-12-30 Fremgangsmåde til fremstilling af Citalopram DK1246813T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/DK1999/000740 WO2001049672A1 (en) 1999-12-30 1999-12-30 Method for the preparation of citalopram

Publications (1)

Publication Number Publication Date
DK1246813T3 true DK1246813T3 (da) 2004-03-01

Family

ID=8157174

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99962133T DK1246813T3 (da) 1999-12-30 1999-12-30 Fremgangsmåde til fremstilling af Citalopram

Country Status (28)

Country Link
US (2) US20020198391A1 (de)
EP (1) EP1246813B1 (de)
JP (1) JP2003519218A (de)
KR (1) KR100653141B1 (de)
CN (1) CN1211377C (de)
AT (1) ATE253568T1 (de)
AU (1) AU1858400A (de)
BR (1) BR9917604A (de)
CA (1) CA2395733C (de)
CZ (1) CZ20022627A3 (de)
DE (1) DE69912652T2 (de)
DK (1) DK1246813T3 (de)
EA (1) EA004055B1 (de)
ES (1) ES2207312T3 (de)
HK (1) HK1052512B (de)
HR (1) HRP20020633A2 (de)
HU (1) HUP0203840A3 (de)
IL (2) IL150367A0 (de)
IS (1) IS2167B (de)
MX (1) MXPA02006504A (de)
NO (1) NO328359B1 (de)
PL (1) PL198803B1 (de)
PT (1) PT1246813E (de)
SI (1) SI1246813T1 (de)
SK (1) SK11052002A3 (de)
TR (1) TR200201688T2 (de)
UA (1) UA73336C2 (de)
WO (1) WO2001049672A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200102957T2 (tr) 1999-04-14 2004-12-21 H. Lundbeck A/S Sitalopram hazırlanması için metod.
SI1246812T1 (en) 1999-12-28 2004-08-31 H. Lundbeck A/S Method for the preparation of citalopram
EA005134B1 (ru) 2000-01-14 2004-12-30 Х.Лундбекк А/С Способ получения 5-цианофталида
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
NZ521201A (en) 2000-03-13 2004-02-27 H Method for the preparation of citalopram
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
CN1427835A (zh) * 2000-03-13 2003-07-02 H·隆德贝克有限公司 5-取代的1-(4-氟苯基)-1,3-二氢异苯并呋喃的分步烷基化
ATE257832T1 (de) 2000-03-14 2004-01-15 Lundbeck & Co As H Verfahren zur herstellung von citalopram
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
US6339182B1 (en) * 2000-06-20 2002-01-15 Chevron U.S.A. Inc. Separation of olefins from paraffins using ionic liquid solutions
US20050154052A1 (en) * 2003-03-24 2005-07-14 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
CN100457747C (zh) * 2006-11-21 2009-02-04 浙江大学 抗抑郁药西酞普兰关键中间体5-氰基苯酞的制备工艺
CN103127815B (zh) * 2013-02-19 2015-10-28 浙江大学 一种利用卤硫作用提高二氧化硫捕集性能的方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143702A (de) 1965-03-18
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
US4665181A (en) * 1984-05-17 1987-05-12 Pennwalt Corporation Anti-inflammatory phthalazinones
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
JPH0881456A (ja) * 1994-09-14 1996-03-26 Sumitomo Chem Co Ltd 1,1,3,3−テトラクロロ−1,3−ジヒドロイソベンゾフラン誘導体の製造法
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
PT1015416E (pt) 1997-07-08 2002-03-28 Lundbeck & Co As H Metodo para a producao de citalopram
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
AU738359B2 (en) * 1997-11-11 2001-09-13 H. Lundbeck A/S Method for the preparation of citalopram
HU228576B1 (en) 1998-10-20 2013-04-29 Lundbeck & Co As H Method for the preparation of citalopram
CA2356188C (en) 1998-12-23 2006-05-23 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
TR200102957T2 (tr) 1999-04-14 2004-12-21 H. Lundbeck A/S Sitalopram hazırlanması için metod.
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ES2169709A1 (es) 1999-10-25 2002-07-01 Lundbeck & Co As H Metodo para la preparacion de citalopram
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
SI1246812T1 (en) 1999-12-28 2004-08-31 H. Lundbeck A/S Method for the preparation of citalopram
EA005134B1 (ru) 2000-01-14 2004-12-30 Х.Лундбекк А/С Способ получения 5-цианофталида
FR2805812A1 (fr) 2000-02-24 2001-09-07 Lundbeck & Co As H Procede de preparation du citalopram
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
IL144817A0 (en) 2000-08-18 2002-06-30 Lundbeck & Co As H Method for the preparation of citalopram
EP1181713B1 (de) 2000-12-22 2004-09-29 H. Lundbeck A/S Verfahren zur vorbereitung von reinem citalopram
PT1181272E (pt) 2000-12-28 2003-01-31 Lundbeck & Co As H Processo para a preparacao de citalopram puro

Also Published As

Publication number Publication date
DE69912652D1 (de) 2003-12-11
US20020198391A1 (en) 2002-12-26
EA004055B1 (ru) 2003-12-25
SI1246813T1 (en) 2004-08-31
TR200201688T2 (tr) 2002-11-21
CA2395733A1 (en) 2001-07-12
PL198803B1 (pl) 2008-07-31
HUP0203840A2 (en) 2003-05-28
DE69912652T2 (de) 2004-06-09
CZ20022627A3 (cs) 2002-10-16
IL150367A0 (en) 2002-12-01
JP2003519218A (ja) 2003-06-17
ATE253568T1 (de) 2003-11-15
IL150367A (en) 2010-06-16
IS6433A (is) 2002-06-19
AU1858400A (en) 2001-07-16
EP1246813A1 (de) 2002-10-09
UA73336C2 (en) 2005-07-15
US20060079700A1 (en) 2006-04-13
CN1211377C (zh) 2005-07-20
WO2001049672A1 (en) 2001-07-12
KR20020073495A (ko) 2002-09-26
CA2395733C (en) 2007-03-20
EP1246813B1 (de) 2003-11-05
NO20023150D0 (no) 2002-06-28
NO20023150L (no) 2002-06-28
HK1052512B (zh) 2006-03-03
HRP20020633A2 (en) 2004-12-31
IS2167B (is) 2006-11-15
EA200200728A1 (ru) 2002-12-26
SK11052002A3 (sk) 2003-01-09
HUP0203840A3 (en) 2005-02-28
PL355531A1 (en) 2004-05-04
PT1246813E (pt) 2004-02-27
ES2207312T3 (es) 2004-05-16
MXPA02006504A (es) 2002-12-09
BR9917604A (pt) 2002-12-31
CN1391566A (zh) 2003-01-15
KR100653141B1 (ko) 2006-12-01
NO328359B1 (no) 2010-02-01
HK1052512A1 (en) 2003-09-19
US7271273B2 (en) 2007-09-18

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