DK124196B - Analogifremgangsmåde til fremstilling af 9α,21-difluor-11β-hydroxy-16-methylen-17α-propionyloxypregna-1,4-dien-3,20-dion eller den tilsvarende 11-oxoforbindelse. - Google Patents

Analogifremgangsmåde til fremstilling af 9α,21-difluor-11β-hydroxy-16-methylen-17α-propionyloxypregna-1,4-dien-3,20-dion eller den tilsvarende 11-oxoforbindelse.

Info

Publication number
DK124196B
DK124196B DK305770AA DK305770A DK124196B DK 124196 B DK124196 B DK 124196B DK 305770A A DK305770A A DK 305770AA DK 305770 A DK305770 A DK 305770A DK 124196 B DK124196 B DK 124196B
Authority
DK
Denmark
Prior art keywords
propionyloxypregna
dione
difluoro
diene
methylene
Prior art date
Application number
DK305770AA
Other languages
English (en)
Inventor
P May
J Elks
G Phillipps
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of DK124196B publication Critical patent/DK124196B/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK305770AA 1969-06-12 1970-06-12 Analogifremgangsmåde til fremstilling af 9α,21-difluor-11β-hydroxy-16-methylen-17α-propionyloxypregna-1,4-dien-3,20-dion eller den tilsvarende 11-oxoforbindelse. DK124196B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB29866/69A GB1261650A (en) 1969-06-12 1969-06-12 9alpha,21-DIHALOPREGNANE COMPOUNDS

Publications (1)

Publication Number Publication Date
DK124196B true DK124196B (da) 1972-09-25

Family

ID=10298463

Family Applications (1)

Application Number Title Priority Date Filing Date
DK305770AA DK124196B (da) 1969-06-12 1970-06-12 Analogifremgangsmåde til fremstilling af 9α,21-difluor-11β-hydroxy-16-methylen-17α-propionyloxypregna-1,4-dien-3,20-dion eller den tilsvarende 11-oxoforbindelse.

Country Status (14)

Country Link
JP (1) JPS4815287B1 (da)
BE (1) BE751876R (da)
BR (1) BR6915172D0 (da)
CH (1) CH590885A5 (da)
DE (1) DE2029143C3 (da)
DK (1) DK124196B (da)
ES (1) ES380698A2 (da)
FR (1) FR2052960B2 (da)
GB (1) GB1261650A (da)
IE (1) IE34656B1 (da)
IL (1) IL34712A (da)
NL (1) NL173171C (da)
PH (1) PH10364A (da)
ZA (1) ZA703860B (da)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB913942A (en) * 1958-07-31 1962-12-28 Merck & Co Inc Steroid compounds

Also Published As

Publication number Publication date
FR2052960B2 (da) 1974-05-24
NL173171C (nl) 1983-12-16
IE34656B1 (en) 1975-07-09
BR6915172D0 (pt) 1973-02-08
ES380698A2 (es) 1975-04-01
DE2029143B2 (de) 1978-07-06
FR2052960A2 (da) 1971-04-16
ZA703860B (en) 1971-02-24
BE751876R (fr) 1970-12-14
NL7008655A (da) 1970-12-15
DE2029143C3 (de) 1979-03-01
GB1261650A (en) 1972-01-26
DE2029143A1 (de) 1970-12-17
NL173171B (nl) 1983-07-18
IL34712A (en) 1973-11-28
IE34656L (en) 1970-12-12
PH10364A (en) 1977-01-18
CH590885A5 (da) 1977-08-31
JPS4815287B1 (da) 1973-05-14

Similar Documents

Publication Publication Date Title
DK129835B (da) Analogifremgangsmåde til fremstilling af 2-chlor-6α-fluor-16α-methyl-pregna-1,4-dien-3,20-dioner.
DK126500B (da) Analogifremgangsmåde til fremstilling af 11-oxygenerede 9α,21-dihalogen-17α-alkanoyloxy-pregn-4-en-3,20-dioner.
DK129988B (da) Fremgangsmåde til fremstilling af 17-monoestere af 17α,21-dihydroxy-20-keto-steroidforbindelser af pregnanrækken.
DK120234B (da) Fremgangsmåde til fremstilling af 17α-monocarboxylsyreestere af 11β, 17α, 21-trihydroxysteroider af pregnanrækken.
DK128352B (da) Analogifremgangsmåde til fremstilling af 9α-fluor-11β-hydroxypregna-1,4-dien-3,20-dion-[17α,16α-d]-oxazolidinoxaziner.
DK129704B (da) Fremgangsmåde til fremstilling af 17α-klor-6α-fluor-16α-methylpregna-1,4-dien-3,20-dion-21-oler eller estere deraf.
DK129039B (da) Fremgangsmåde til fremstilling af 11β,16α17α21-tetrahydroxy-pregna-1,4-dien-3,20-dioner eller de tilsvarende 16,17-acetonider.
DK130991B (da) Fremgangsmåde til fremstilling af 16beta-metyl-9alfa-fluor-11beta-17alfa,21-trihydroxy-1,4-pregnadien-3,20-dion eller dets 21-acylater.
DK120190B (da) Analogifremgangsmåde til fremstilling af terapeutisk aktive 17-estere af 9α,11β-dihalogen-16α-alkyl-Δ<1,4>-pregnadien-17α,21-diol-3,20-dioner.
DK124196B (da) Analogifremgangsmåde til fremstilling af 9α,21-difluor-11β-hydroxy-16-methylen-17α-propionyloxypregna-1,4-dien-3,20-dion eller den tilsvarende 11-oxoforbindelse.
DK133382B (da) Analogifremgangsmåde til fremstilling af 6alfa,9alfa-diflour-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-dien-3,20-dion-17,21-diacetat.
DK122454B (da) Fremgangsmåde til fremstilling af 9α,21,21-triklor-11β-fluor-pregn-4-en-3,20-dioner.
DK124539B (da) Fremgangsmåde til fremstilling af 6-hydroxy-3-keto-Δ<1,4>-steroider af pregnan- eller androstanrækken.
DK126647B (da) Analogifremgangsmåde til fremstilling af 16α,17α-(substitueret-methylen)-steroider af pregnanrækken.
DK120235B (da) Analogifremgangsmåde til fremstilling af 9α, 11β-disubstituerede 6α-fluor-16α-methyl-21-halogen-4-pregnen-3,20-dionderivater.
DK122812B (da) Analogifremgangsmåde til fremstilling af 9α-fluor-11β,21-dihydroxy-16α-17α-(2-propenylidendioxy)-pregna-1,4-dien-3,20-dion eller 21-estere deraf.
DK127420B (da) Analogifremgangsmåde til fremstilling af 6α-fluor-16α,18-dimethyl-1,4-pregnadien-3,20-dionderivater.
DK130646B (da) Analogifremgangsmåde til fremstilling af 17- og/eller 21-alkanoyloxy-11beta-klor-16beta-metylpregna-1,4-dien-3,20-dioner.
DK122811B (da) Fremgangsmåde til fremstilling af 11α-hydroksy-3-okso-Δ<1,4>-steroider af pregnan- eller androstanrækken ved blandingsforgæring.
DK127924B (da) Analogifremgangsmåde til fremstilling af 7α-methyl-3,16α,17β-trihydroxy-Δ1,3,5(10)-estratrien.
DK128897B (da) Analogifremgangsmåde til fremstilling af 2,9α,-11β-trichlor-6α-fluor-16α-methyl-Δ<1,4>-pregnadien-17α,21-diol-3,20-dion eller estere deraf.
DK139298B (da) Fremgangsmåde til fremstilling af desA-9beta-steroider af androstan-, pregnan- eller diosgeninrækken.
DK129452B (da) Analogifremgangsmåde til fremstilling af 9α-fluor-11β,21-dihydroxy-pregna-1,4-dien-3,20-dion-[17α,16α-d]-oxazolidiner eller oxazolidinooxaziner.
DK132121B (da) Fremgangsmåde til fremstilling af 17alfa-hydroxypregna-4,9(11)-dien-3,20-dion.
DK132226B (da) Fremgangsmåde til fremstilling af 16alfa, 17alfa-dialkylsteroider af pregnanrækken.