DK124196B - Analogous process for the preparation of 9α, 21-difluoro-11β-hydroxy-16-methylene-17α-propionyloxypregna-1,4-diene-3,20-dione or the corresponding 11-oxo compound. - Google Patents

Analogous process for the preparation of 9α, 21-difluoro-11β-hydroxy-16-methylene-17α-propionyloxypregna-1,4-diene-3,20-dione or the corresponding 11-oxo compound.

Info

Publication number
DK124196B
DK124196B DK305770AA DK305770A DK124196B DK 124196 B DK124196 B DK 124196B DK 305770A A DK305770A A DK 305770AA DK 305770 A DK305770 A DK 305770A DK 124196 B DK124196 B DK 124196B
Authority
DK
Denmark
Prior art keywords
propionyloxypregna
dione
difluoro
diene
methylene
Prior art date
Application number
DK305770AA
Other languages
Danish (da)
Inventor
P May
J Elks
G Phillipps
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of DK124196B publication Critical patent/DK124196B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DK305770AA 1969-06-12 1970-06-12 Analogous process for the preparation of 9α, 21-difluoro-11β-hydroxy-16-methylene-17α-propionyloxypregna-1,4-diene-3,20-dione or the corresponding 11-oxo compound. DK124196B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB29866/69A GB1261650A (en) 1969-06-12 1969-06-12 9alpha,21-DIHALOPREGNANE COMPOUNDS

Publications (1)

Publication Number Publication Date
DK124196B true DK124196B (en) 1972-09-25

Family

ID=10298463

Family Applications (1)

Application Number Title Priority Date Filing Date
DK305770AA DK124196B (en) 1969-06-12 1970-06-12 Analogous process for the preparation of 9α, 21-difluoro-11β-hydroxy-16-methylene-17α-propionyloxypregna-1,4-diene-3,20-dione or the corresponding 11-oxo compound.

Country Status (14)

Country Link
JP (1) JPS4815287B1 (en)
BE (1) BE751876R (en)
BR (1) BR6915172D0 (en)
CH (1) CH590885A5 (en)
DE (1) DE2029143C3 (en)
DK (1) DK124196B (en)
ES (1) ES380698A2 (en)
FR (1) FR2052960B2 (en)
GB (1) GB1261650A (en)
IE (1) IE34656B1 (en)
IL (1) IL34712A (en)
NL (1) NL173171C (en)
PH (1) PH10364A (en)
ZA (1) ZA703860B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB913942A (en) * 1958-07-31 1962-12-28 Merck & Co Inc Steroid compounds

Also Published As

Publication number Publication date
NL173171B (en) 1983-07-18
DE2029143C3 (en) 1979-03-01
GB1261650A (en) 1972-01-26
IE34656L (en) 1970-12-12
ES380698A2 (en) 1975-04-01
PH10364A (en) 1977-01-18
CH590885A5 (en) 1977-08-31
JPS4815287B1 (en) 1973-05-14
IE34656B1 (en) 1975-07-09
NL7008655A (en) 1970-12-15
DE2029143B2 (en) 1978-07-06
BR6915172D0 (en) 1973-02-08
FR2052960A2 (en) 1971-04-16
ZA703860B (en) 1971-02-24
FR2052960B2 (en) 1974-05-24
NL173171C (en) 1983-12-16
IL34712A (en) 1973-11-28
BE751876R (en) 1970-12-14
DE2029143A1 (en) 1970-12-17

Similar Documents

Publication Publication Date Title
DK129835B (en) Analogous process for the preparation of 2-chloro-6α-fluoro-16α-methyl-pregna-1,4-diene-3,20-diones.
DK126500B (en) Analogous process for the preparation of 11-oxygenated 9α, 21-dihalo-17α-alkanoyloxy-pregn-4-ene-3,20-diones.
DK129988B (en) Process for the preparation of 17-monoesters of 17α, 21-dihydroxy-20-keto-steroid compounds of the pregnane series.
DK120234B (en) Process for the preparation of 17α-monocarboxylic acid esters of 11β, 17α, 21-trihydroxysteroids of the pregnane series.
DK128352B (en) Analogous process for the preparation of 9α-fluoro-11β-hydroxypregna-1,4-diene-3,20-dione- [17α, 16α-d] -oxazolidinoxazines.
DK129704B (en) Process for the preparation of 17α-chloro-6α-fluoro-16α-methylpregna-1,4-diene-3,20-dione-21-oils or esters thereof.
DK129039B (en) Process for the preparation of 11β, 16α17α21-tetrahydroxy-pregna-1,4-diene-3,20-diones or the corresponding 16,17-acetonides.
DK130991B (en) Process for the preparation of 16beta-methyl-9alpha-fluoro-11beta-17alpha, 21-trihydroxy-1,4-pregnadiene-3,20-dione or its 21-acylates.
DK120190B (en) Analogous process for the preparation of therapeutically active 17-esters of 9α, 11β-dihalo-16α-alkyl-Δ <1,4> -pregnadiene-17α, 21-diol-3,20-diones.
DK131474B (en) Analogous process for the preparation of 9alpha-halogen-11beta, 17alpha, 21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione-21-adamantane-1'-carboxylates.
DK124196B (en) Analogous process for the preparation of 9α, 21-difluoro-11β-hydroxy-16-methylene-17α-propionyloxypregna-1,4-diene-3,20-dione or the corresponding 11-oxo compound.
DK133382B (en) Analogous process for the preparation of 6alpha, 9alpha-difluor-11beta, 17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione-17,21-diacetate.
DK122454B (en) Process for the preparation of 9α, 21,21-trichloro-11β-fluoro-pregn-4-ene-3,20-diones.
DK124539B (en) Process for the preparation of 6-hydroxy-3-keto-Δ <1,4> steroids of the pregnane or androstane series.
DK126647B (en) Analogous process for the preparation of 16α, 17α- (substituted-methylene) steroids of the pregnane series.
DK120235B (en) Analogous process for the preparation of 9α, 11β-disubstituted 6α-fluoro-16α-methyl-21-halogen-4-pregnene-3,20-dione derivatives.
DK122812B (en) Analogous process for the preparation of 9α-fluoro-11β, 21-dihydroxy-16α-17α- (2-propenylidenedioxy) -pregna-1,4-diene-3,20-dione or 21-esters thereof.
DK127420B (en) Analogous process for the preparation of 6α-fluoro-16α, 18-dimethyl-1,4-pregnadiene-3,20-dione derivatives.
DK130646B (en) Analogous process for the preparation of 17- and / or 21-alkanoyloxy-11beta-chloro-16beta-methylpregna-1,4-diene-3,20-diones.
DK122811B (en) Process for the preparation of 11α-hydroxy-3-oxo-Δ <1,4> steroids from the pregnane or androstane series by mixed fermentation.
DK127924B (en) Analogous process for the preparation of 7α-methyl-3,16α, 17β-trihydroxy-Δ1,3,5 (10) -estratriene.
DK128897B (en) Analogous process for the preparation of 2,9α, -11β-trichloro-6α-fluoro-16α-methyl-Δ <1,4> -pregnadiene-17α, 21-diol-3,20-dione or esters thereof.
DK139298B (en) Process for the preparation of desA-9beta steroids from the androstane, pregnane or diosgenin series.
DK129452B (en) Analogous process for the preparation of 9α-fluoro-11β, 21-dihydroxy-pregna-1,4-diene-3,20-dione- [17α, 16α-d] -oxazolidines or oxazolidinooxazines.
DK132121B (en) Process for the preparation of 17alpha-hydroxypregna-4,9 (11) -diene-3,20-dione.