DK133382B - Analogifremgangsmåde til fremstilling af 6alfa,9alfa-diflour-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-dien-3,20-dion-17,21-diacetat. - Google Patents

Analogifremgangsmåde til fremstilling af 6alfa,9alfa-diflour-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-dien-3,20-dion-17,21-diacetat.

Info

Publication number
DK133382B
DK133382B DK128173AA DK128173A DK133382B DK 133382 B DK133382 B DK 133382B DK 128173A A DK128173A A DK 128173AA DK 128173 A DK128173 A DK 128173A DK 133382 B DK133382 B DK 133382B
Authority
DK
Denmark
Prior art keywords
16beta
9alpha
6alpha
methylpregna
11beta
Prior art date
Application number
DK128173AA
Other languages
English (en)
Other versions
DK133382C (da
Inventor
Donald Emory Ayer
Carl Alvin Schlagel
Gordon Leonard Flynn
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of DK133382B publication Critical patent/DK133382B/da
Application granted granted Critical
Publication of DK133382C publication Critical patent/DK133382C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK128173AA 1972-03-09 1973-03-08 Analogifremgangsmåde til fremstilling af 6alfa,9alfa-diflour-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-dien-3,20-dion-17,21-diacetat. DK133382B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23333772A 1972-03-09 1972-03-09
US31697372A 1972-12-20 1972-12-20

Publications (2)

Publication Number Publication Date
DK133382B true DK133382B (da) 1976-05-10
DK133382C DK133382C (da) 1976-10-04

Family

ID=26926821

Family Applications (1)

Application Number Title Priority Date Filing Date
DK128173AA DK133382B (da) 1972-03-09 1973-03-08 Analogifremgangsmåde til fremstilling af 6alfa,9alfa-diflour-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-dien-3,20-dion-17,21-diacetat.

Country Status (13)

Country Link
JP (3) JPS5331156B2 (da)
AR (1) AR197216A1 (da)
AU (1) AU468257B2 (da)
CH (3) CH580116A5 (da)
DE (1) DE2365992C3 (da)
DK (1) DK133382B (da)
ES (1) ES412235A1 (da)
FR (1) FR2181802B1 (da)
GB (1) GB1403962A (da)
HK (1) HK62680A (da)
NL (1) NL165178C (da)
PH (1) PH14703A (da)
SE (1) SE396756B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1430223A (en) * 1973-10-25 1976-03-31 Upjohn Co Anti-inflammatory composition comprising steroids
ZA77943B (en) * 1976-03-19 1977-12-28 Upjohn Co Topical steroid clindamycin preparations
NL187577C (nl) * 1978-04-05 1991-11-18 Sibla Srl 3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen.
EP0030615B1 (en) 1979-11-16 1984-08-29 STEROSYNT Ltd. 6-alpha-9-alpha-difluoro-16-beta-methyl-prednisolone-17,21 diesters and pharmaceutical compositions containing them
JPH0240957Y2 (da) * 1986-08-30 1990-10-31

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB933859A (da) * 1958-09-06 1963-08-14 Syntex S.A.

Also Published As

Publication number Publication date
DE2365992C3 (de) 1982-05-19
CH580117A5 (da) 1976-09-30
NL7303262A (da) 1973-09-11
NL165178B (nl) 1980-10-15
JPS4899157A (da) 1973-12-15
FR2181802A1 (da) 1973-12-07
DK133382C (da) 1976-10-04
FR2181802B1 (da) 1976-10-22
AU468257B2 (en) 1976-01-08
AR197216A1 (es) 1974-03-22
PH14703A (en) 1981-11-10
JPS5344465B2 (da) 1978-11-29
ES412235A1 (es) 1976-01-01
JPS5227760A (en) 1977-03-02
DE2365992A1 (de) 1977-05-18
AU5257973A (en) 1974-08-29
DE2365992B2 (de) 1981-08-06
CH580116A5 (da) 1976-09-30
HK62680A (en) 1980-11-14
JPS5331156B2 (da) 1978-08-31
CH580118A5 (da) 1976-09-30
NL165178C (nl) 1981-03-16
GB1403962A (en) 1975-08-28
JPS5344464B2 (da) 1978-11-29
SE396756B (sv) 1977-10-03
JPS5227761A (en) 1977-03-02

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