ES380698A2 - Un procedimiento para la preparacion de nuevos esteroides anti-inflamatorios de la serie del pregnano. - Google Patents
Un procedimiento para la preparacion de nuevos esteroides anti-inflamatorios de la serie del pregnano.Info
- Publication number
- ES380698A2 ES380698A2 ES380698A ES380698A ES380698A2 ES 380698 A2 ES380698 A2 ES 380698A2 ES 380698 A ES380698 A ES 380698A ES 380698 A ES380698 A ES 380698A ES 380698 A2 ES380698 A2 ES 380698A2
- Authority
- ES
- Spain
- Prior art keywords
- dihalopregnane
- 9alpha
- compounds
- compositions
- propionyloxypregna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 229930193140 Neomycin Natural products 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960004927 neomycin Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
Mejoras introducidas en el objeto de la Patente principal número 362.679, solicitada el 18 de enero de 1.969, por "Un procedimiento para la preparación de nuevos esteroides anti- inflamatorios de la serie del pregnano", de la fórmula general **(Fórmula-01)** en la que X representa un grupo hidroxi en la configuración beta o un grupo ceto), caracterizadas porque se acila un compuesto de la fórmula **(Fórmula-02)** para introducir el radical propionilo en el grupo 17-hidroxi.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB29866/69A GB1261650A (en) | 1969-06-12 | 1969-06-12 | 9alpha,21-DIHALOPREGNANE COMPOUNDS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES380698A2 true ES380698A2 (es) | 1975-04-01 |
Family
ID=10298463
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES380698A Expired ES380698A2 (es) | 1969-06-12 | 1970-07-12 | Un procedimiento para la preparacion de nuevos esteroides anti-inflamatorios de la serie del pregnano. |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS4815287B1 (es) |
| BE (1) | BE751876R (es) |
| BR (1) | BR6915172D0 (es) |
| CH (1) | CH590885A5 (es) |
| DE (1) | DE2029143C3 (es) |
| DK (1) | DK124196B (es) |
| ES (1) | ES380698A2 (es) |
| FR (1) | FR2052960B2 (es) |
| GB (1) | GB1261650A (es) |
| IE (1) | IE34656B1 (es) |
| IL (1) | IL34712A (es) |
| NL (1) | NL173171C (es) |
| PH (1) | PH10364A (es) |
| ZA (1) | ZA703860B (es) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB913942A (en) * | 1958-07-31 | 1962-12-28 | Merck & Co Inc | Steroid compounds |
-
1969
- 1969-06-12 GB GB29866/69A patent/GB1261650A/en not_active Expired
- 1969-12-15 BR BR215172/69A patent/BR6915172D0/pt unknown
-
1970
- 1970-06-08 ZA ZA703860A patent/ZA703860B/xx unknown
- 1970-06-10 PH PH11523A patent/PH10364A/en unknown
- 1970-06-11 IE IE760/70A patent/IE34656B1/xx unknown
- 1970-06-12 BE BE751876D patent/BE751876R/xx active
- 1970-06-12 CH CH895470A patent/CH590885A5/xx not_active IP Right Cessation
- 1970-06-12 JP JP45050404A patent/JPS4815287B1/ja active Pending
- 1970-06-12 DK DK305770AA patent/DK124196B/da unknown
- 1970-06-12 FR FR7021607A patent/FR2052960B2/fr not_active Expired
- 1970-06-12 NL NLAANVRAGE7008655,A patent/NL173171C/xx active
- 1970-06-12 DE DE702029143A patent/DE2029143C3/de not_active Expired
- 1970-06-12 IL IL34712A patent/IL34712A/xx unknown
- 1970-07-12 ES ES380698A patent/ES380698A2/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL34712A (en) | 1973-11-28 |
| FR2052960B2 (es) | 1974-05-24 |
| ZA703860B (en) | 1971-02-24 |
| DK124196B (da) | 1972-09-25 |
| FR2052960A2 (es) | 1971-04-16 |
| JPS4815287B1 (es) | 1973-05-14 |
| IE34656L (en) | 1970-12-12 |
| NL173171B (nl) | 1983-07-18 |
| DE2029143B2 (de) | 1978-07-06 |
| BE751876R (fr) | 1970-12-14 |
| IE34656B1 (en) | 1975-07-09 |
| PH10364A (en) | 1977-01-18 |
| NL7008655A (es) | 1970-12-15 |
| DE2029143A1 (de) | 1970-12-17 |
| GB1261650A (en) | 1972-01-26 |
| CH590885A5 (es) | 1977-08-31 |
| BR6915172D0 (pt) | 1973-02-08 |
| NL173171C (nl) | 1983-12-16 |
| DE2029143C3 (de) | 1979-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19900217 |