DK122191A - Benzimidazolderivat og fysiologisk acceptable salte heraf samt fremgangsmaade til fremstilling af samme - Google Patents

Benzimidazolderivat og fysiologisk acceptable salte heraf samt fremgangsmaade til fremstilling af samme Download PDF

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Publication number
DK122191A
DK122191A DK122191A DK122191A DK122191A DK 122191 A DK122191 A DK 122191A DK 122191 A DK122191 A DK 122191A DK 122191 A DK122191 A DK 122191A DK 122191 A DK122191 A DK 122191A
Authority
DK
Denmark
Prior art keywords
acceptable salts
physiologically acceptable
procedures
preparation
same
Prior art date
Application number
DK122191A
Other languages
Danish (da)
English (en)
Other versions
DK122191D0 (da
Inventor
Arne Elof Braendstroem
Per Lennart Lindberg
Gunnel Elisabeth Sunden
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE19888804629A external-priority patent/SE8804629D0/xx
Priority claimed from SE8902170A external-priority patent/SE8902170D0/xx
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of DK122191D0 publication Critical patent/DK122191D0/da
Publication of DK122191A publication Critical patent/DK122191A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK122191A 1988-12-22 1991-06-21 Benzimidazolderivat og fysiologisk acceptable salte heraf samt fremgangsmaade til fremstilling af samme DK122191A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE19888804629A SE8804629D0 (sv) 1988-12-22 1988-12-22 New therapeutically active compounds
SE8902170A SE8902170D0 (sv) 1989-06-16 1989-06-16 Therapeutically active compounds
PCT/SE1989/000739 WO1990006924A1 (en) 1988-12-22 1989-12-20 Compound with gastric acid inhibitory effect and process for its preparation

Publications (2)

Publication Number Publication Date
DK122191D0 DK122191D0 (da) 1991-06-21
DK122191A true DK122191A (da) 1991-06-24

Family

ID=26660387

Family Applications (1)

Application Number Title Priority Date Filing Date
DK122191A DK122191A (da) 1988-12-22 1991-06-21 Benzimidazolderivat og fysiologisk acceptable salte heraf samt fremgangsmaade til fremstilling af samme

Country Status (27)

Country Link
US (1) US5025024A (ja)
EP (1) EP0449935B1 (ja)
JP (1) JP2793905B2 (ja)
KR (1) KR910700248A (ja)
CN (1) CN1028233C (ja)
AT (1) ATE110723T1 (ja)
AU (1) AU639429B2 (ja)
BG (1) BG60101B2 (ja)
CA (1) CA2005980C (ja)
CS (1) CS276361B6 (ja)
DE (1) DE68917937T2 (ja)
DK (1) DK122191A (ja)
EG (1) EG19302A (ja)
FI (1) FI913034A0 (ja)
GR (1) GR1000316B (ja)
HU (1) HUT57204A (ja)
IE (1) IE64199B1 (ja)
IL (1) IL92799A (ja)
LV (1) LV10267B (ja)
MY (1) MY129946A (ja)
NO (1) NO178336C (ja)
NZ (1) NZ231874A (ja)
PH (1) PH27446A (ja)
PL (1) PL160767B1 (ja)
PT (1) PT92649B (ja)
WO (1) WO1990006924A1 (ja)
YU (1) YU47338B (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US20040006111A1 (en) * 2002-01-25 2004-01-08 Kenneth Widder Transmucosal delivery of proton pump inhibitors
US20040248942A1 (en) * 2003-02-20 2004-12-09 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
US20050031700A1 (en) * 2003-07-18 2005-02-10 Sanatarus, Inc. Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
WO2005007115A2 (en) * 2003-07-18 2005-01-27 Santarus, Inc. Pharmaceutical composition for inhibiting acid secretion
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (ja) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
HU195220B (en) * 1983-05-03 1988-04-28 Byk Gulden Lomberg Chem Fqb Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150979A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
US4738975A (en) * 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
NZ222495A (en) * 1986-11-21 1991-04-26 Haessle Ab Benzimidazole derivatives and pharmaceutical compositions
FI96860C (fi) * 1987-06-17 1996-09-10 Eisai Co Ltd Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi

Also Published As

Publication number Publication date
LV10267A (lv) 1994-10-20
LV10267B (en) 1995-02-20
NO912414L (no) 1991-08-06
JP2793905B2 (ja) 1998-09-03
NO178336C (no) 1996-03-06
PH27446A (en) 1993-07-02
BG60101B2 (bg) 1993-10-29
HUT57204A (en) 1991-11-28
MY129946A (en) 2007-05-31
DE68917937D1 (de) 1994-10-06
PT92649A (pt) 1990-06-29
WO1990006924A1 (en) 1990-06-28
GR890100833A (en) 1991-03-15
IE64199B1 (en) 1995-07-12
EG19302A (en) 1994-11-30
CN1043937A (zh) 1990-07-18
IL92799A (en) 1994-01-25
JPH04502460A (ja) 1992-05-07
AU639429B2 (en) 1993-07-29
US5025024A (en) 1991-06-18
CA2005980C (en) 1999-07-13
CS276361B6 (en) 1992-05-13
KR910700248A (ko) 1991-03-14
IE894050L (en) 1990-06-22
CN1028233C (zh) 1995-04-19
ATE110723T1 (de) 1994-09-15
GR1000316B (el) 1992-06-25
NZ231874A (en) 1992-05-26
PL160767B1 (pl) 1993-04-30
CA2005980A1 (en) 1990-06-22
YU242789A (en) 1991-04-30
FI913034A0 (fi) 1991-06-20
NO912414D0 (no) 1991-06-20
AU4813290A (en) 1990-07-10
DE68917937T2 (de) 1995-01-05
YU47338B (sh) 1995-01-31
EP0449935A1 (en) 1991-10-09
PT92649B (pt) 1995-09-12
IL92799A0 (en) 1990-09-17
HU901095D0 (en) 1991-09-30
EP0449935B1 (en) 1994-08-31
DK122191D0 (da) 1991-06-21
CS734389A3 (en) 1992-01-15
NO178336B (no) 1995-11-27

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