DK1214097T3 - Nukleinsyrer kodende for polyepitop-polypeptider - Google Patents

Nukleinsyrer kodende for polyepitop-polypeptider

Info

Publication number
DK1214097T3
DK1214097T3 DK00965119T DK00965119T DK1214097T3 DK 1214097 T3 DK1214097 T3 DK 1214097T3 DK 00965119 T DK00965119 T DK 00965119T DK 00965119 T DK00965119 T DK 00965119T DK 1214097 T3 DK1214097 T3 DK 1214097T3
Authority
DK
Denmark
Prior art keywords
nucleic acids
acids encoding
polyepitope polypeptides
encoding polyepitope
polypeptides
Prior art date
Application number
DK00965119T
Other languages
Danish (da)
English (en)
Inventor
Roman M Chicz
Robert C Urban
Mary Lynne Hedley
Original Assignee
Eisai Corp North America
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Corp North America filed Critical Eisai Corp North America
Application granted granted Critical
Publication of DK1214097T3 publication Critical patent/DK1214097T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK00965119T 1999-09-16 2000-09-18 Nukleinsyrer kodende for polyepitop-polypeptider DK1214097T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US39853499A 1999-09-16 1999-09-16
US15466599P 1999-09-16 1999-09-16
US45817399A 1999-12-09 1999-12-09
US16984699P 1999-12-09 1999-12-09
PCT/US2000/025559 WO2001019408A1 (en) 1999-09-16 2000-09-18 Nucleic acids encoding polyepitope polypeptides

Publications (1)

Publication Number Publication Date
DK1214097T3 true DK1214097T3 (da) 2009-11-16

Family

ID=27496146

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00965119T DK1214097T3 (da) 1999-09-16 2000-09-18 Nukleinsyrer kodende for polyepitop-polypeptider

Country Status (10)

Country Link
EP (2) EP2100620A1 (es)
JP (1) JP2003509035A (es)
AU (1) AU785319B2 (es)
CA (1) CA2384987A1 (es)
CY (1) CY1109699T1 (es)
DE (1) DE60042556D1 (es)
DK (1) DK1214097T3 (es)
ES (1) ES2330078T3 (es)
PT (1) PT1214097E (es)
WO (1) WO2001019408A1 (es)

Families Citing this family (27)

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Publication number Priority date Publication date Assignee Title
US20030166549A1 (en) * 2000-02-02 2003-09-04 Klaus Schughart Targeting peptides
FR2824326B1 (fr) * 2001-05-04 2004-03-19 Commissariat Energie Atomique Melange de peptides issus des proteines e6 et/ou e7 de papillomavirus et leurs applications
GB0118532D0 (en) 2001-07-30 2001-09-19 Isis Innovation Materials and methods relating to improved vaccination strategies
DE60238864D1 (de) 2001-11-07 2011-02-17 Mankind Corp Für epitope von antigenen kodierende expressionsvektoren und verfahren zu deren konzeption
WO2003095642A2 (en) * 2002-05-07 2003-11-20 Aventis Pasteur, Ltd. Polyepitopes and mini-genes for cancer treatment
AU2002950183A0 (en) * 2002-07-12 2002-09-12 The Council Of The Queensland Institute Of Medical Research Expression of hydrophobic proteins
WO2004037175A2 (en) 2002-10-21 2004-05-06 Mgi Pharma Biologics, Inc. Compositions and methods for treating human papillomavirus-mediated disease
WO2004085466A2 (en) 2003-03-28 2004-10-07 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Immunogenic hiv-1 multi-clade, multivalent constructs and methods of their use
EP1638993A4 (en) * 2003-06-10 2007-05-09 Univ Melbourne IMMUNOMODULATING COMPOSITIONS, APPLICATIONS THEREOF AND METHOD FOR THE PRODUCTION THEREOF
US8877206B2 (en) 2007-03-22 2014-11-04 Pds Biotechnology Corporation Stimulation of an immune response by cationic lipids
JP5971945B2 (ja) 2008-04-17 2016-08-17 ピーディーエス バイオテクノロジー コーポレイションＰｄｓ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐｏｒａｔｉｏｎ カチオン性脂質の鏡像異性体による免疫応答の刺激
EP2545071A2 (en) * 2010-03-09 2013-01-16 Maksyutov, Amir Polyepitope constructs and methods for their preparation and use
PL2604629T3 (pl) 2010-08-13 2018-08-31 Genexine, Inc. Kompozycja do zapobiegania lub leczenia raka szyjki macicy ze wzmacniaczem odporności przeciwko wirusowi brodawczaka ludzkiego
CN105463000B (zh) * 2010-08-13 2021-06-01 株式会社吉耐森 用于预防或治疗宫颈癌的、包含人乳头瘤病毒变形体及免疫增强剂的组合物
CN105463001A (zh) * 2010-08-13 2016-04-06 株式会社吉耐森 用于预防或治疗宫颈癌的、包含人乳头瘤病毒变形体及免疫增强剂的组合物
DK3473267T3 (da) 2011-05-24 2021-10-18 BioNTech SE Individualiserede vacciner mod cancer
NZ730355A (en) 2011-05-24 2022-10-28 Tron Translationale Onkologie An Der Univ Der Johannes Gutenberg Univ Mainz Gemeinnuetzige Gmbh Individualized vaccines for cancer
EP2897639A4 (en) 2012-09-21 2016-05-04 Frank Bedu-Addo IMPROVED VACCINE COMPOSITIONS AND METHODS OF USE
WO2016024255A1 (en) 2014-08-15 2016-02-18 Genexine, Inc. Methods of treating cervical cancer
HUE040440T2 (hu) * 2014-11-04 2019-03-28 Janssen Vaccines & Prevention Bv Terápiás HPV16-oltóanyagok
CA3005251A1 (en) 2015-11-13 2017-05-18 Pds Biotechnology Corporation Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy
JP7110108B2 (ja) * 2015-12-09 2022-08-01 ジンガン メディスン（オーストラリア） プロプライアタリー リミティド 治療用免疫調節組成物
KR20240133779A (ko) 2016-10-05 2024-09-04 피디에스 바이오테크놀러지 코퍼레이션 신규한 hpv16 hla-비제한적 t-세포 백신, 조성물 및 이의 사용 방법
JP2020515283A (ja) * 2016-12-28 2020-05-28 インブバックス，インコーポレーテッド インフルエンザワクチン
US20230241207A1 (en) * 2017-04-03 2023-08-03 Neon Therapeutics, Inc. Protein antigens and uses thereof
WO2020072371A1 (en) * 2018-10-01 2020-04-09 The Wistar Institute Melanoma canine vaccine compositions and methods of use thereof
WO2021215896A1 (en) 2020-04-24 2021-10-28 Genexine, Inc. Method for treating cervical cancer

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04502760A (ja) * 1988-10-03 1992-05-21 レプリゲン・コーポレーション エイズの診断，予防および治療に有効な新規ｈｉｖ蛋白質およびペプチド
PT97073A (pt) * 1990-03-20 1991-10-31 Behringwerke Ag Processo para a preparacao de epitopos soro-reactivos de proteinas de papillomavirus 16 humano (hpv)
US5753233A (en) * 1990-05-10 1998-05-19 Behring Diagnostics Gmbh Seroreactive epitopes on proteins of human papilloma-virus (HPV) 18
DE4015044A1 (de) * 1990-05-10 1991-11-14 Behringwerke Ag Seroreaktive epitope auf proteinen des menschlichen papillomavirus (hpv) 18
SE9001705D0 (sv) * 1990-05-11 1990-05-11 Medscand Ab Saett foer diagnostik av virusbaerande tumoerer genom immunoassay
WO1992005248A1 (en) * 1990-09-26 1992-04-02 Bristol-Myers Squibb Company Human papilloma viral protein expression for use in vaccine compositions
GB9105383D0 (en) * 1991-03-14 1991-05-01 Immunology Ltd An immunotherapeutic for cervical cancer
DK0523391T3 (da) * 1991-07-13 2003-06-23 Dade Behring Marburg Gmbh Anvendelse af HPV-16 E6 og E7 genafledte peptider til diagnostisk formål
IL105554A (en) * 1992-05-05 1999-08-17 Univ Leiden Peptides of human papillomavirus for use in preparations elicit a human T cell response
DE69332485T2 (de) 1992-08-11 2003-11-13 The President And Fellows Of Harvard College, Cambridge Immunmodulierende peptide
US5679509A (en) * 1993-09-28 1997-10-21 University Of New Mexico Methods and a diagnostic aid for distinguishing a subset of HPV that is associated with an increased risk of developing cervical dysplasia and cervical cancer
EP0804249A2 (en) 1994-03-15 1997-11-05 Brown University Research Foundation Polymeric gene delivery system
AUPN015794A0 (en) * 1994-12-20 1995-01-19 Csl Limited Variants of human papilloma virus antigens
US5783567A (en) 1997-01-22 1998-07-21 Pangaea Pharmaceuticals, Inc. Microparticles for delivery of nucleic acid
US6013258A (en) * 1997-10-09 2000-01-11 Zycos Inc. Immunogenic peptides from the HPV E7 protein

Also Published As

Publication number Publication date
PT1214097E (pt) 2009-10-19
WO2001019408A9 (en) 2002-12-05
CY1109699T1 (el) 2014-08-13
AU785319B2 (en) 2007-01-11
EP1214097B3 (en) 2011-07-20
WO2001019408A1 (en) 2001-03-22
ES2330078T3 (es) 2009-12-04
EP1214097A4 (en) 2005-02-02
DE60042556D1 (de) 2011-02-10
EP1214097A1 (en) 2002-06-19
JP2003509035A (ja) 2003-03-11
EP1214097B9 (en) 2010-05-19
AU7589100A (en) 2001-04-17
EP2100620A1 (en) 2009-09-16
EP1214097B1 (en) 2009-07-15
CA2384987A1 (en) 2001-03-22

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