DK1209166T3 - Hidtil ukendte A-500 359-derivater - Google Patents

Hidtil ukendte A-500 359-derivater

Info

Publication number
DK1209166T3
DK1209166T3 DK00953494T DK00953494T DK1209166T3 DK 1209166 T3 DK1209166 T3 DK 1209166T3 DK 00953494 T DK00953494 T DK 00953494T DK 00953494 T DK00953494 T DK 00953494T DK 1209166 T3 DK1209166 T3 DK 1209166T3
Authority
DK
Denmark
Prior art keywords
present
prevention
treatment
bacterial infections
compound described
Prior art date
Application number
DK00953494T
Other languages
Danish (da)
English (en)
Inventor
Hitoshi Hotoda
Masakatsu Kaneko
Masatoshi Inukai
Yasunori Muramatsu
Yukio Utsui
Satoshi Ohya
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Application granted granted Critical
Publication of DK1209166T3 publication Critical patent/DK1209166T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/067—Pyrimidine radicals with ribosyl as the saccharide radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK00953494T 1999-08-20 2000-08-18 Hidtil ukendte A-500 359-derivater DK1209166T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP23393499 1999-08-20
PCT/JP2000/005538 WO2001014399A1 (fr) 1999-08-20 2000-08-18 Nouveaux derives a-500359

Publications (1)

Publication Number Publication Date
DK1209166T3 true DK1209166T3 (da) 2004-07-26

Family

ID=16962911

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00953494T DK1209166T3 (da) 1999-08-20 2000-08-18 Hidtil ukendte A-500 359-derivater

Country Status (25)

Country Link
US (1) US7157442B2 (pt)
EP (1) EP1209166B1 (pt)
KR (1) KR100787849B1 (pt)
CN (1) CN1176936C (pt)
AT (1) ATE263183T1 (pt)
AU (1) AU763492B2 (pt)
BR (1) BR0013435A (pt)
CA (1) CA2382654C (pt)
CZ (1) CZ2002682A3 (pt)
DE (1) DE60009517T2 (pt)
DK (1) DK1209166T3 (pt)
ES (1) ES2216933T3 (pt)
HK (1) HK1044951A1 (pt)
HU (1) HUP0204217A3 (pt)
IL (2) IL148196A0 (pt)
MX (1) MXPA02001817A (pt)
NO (1) NO323556B1 (pt)
NZ (1) NZ517315A (pt)
PL (1) PL353494A1 (pt)
PT (1) PT1209166E (pt)
RU (1) RU2227799C2 (pt)
TR (1) TR200200485T2 (pt)
TW (1) TWI245047B (pt)
WO (1) WO2001014399A1 (pt)
ZA (1) ZA200201409B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1181087C (zh) * 1998-07-09 2004-12-22 三共株式会社 新的抗菌化合物
US7456222B2 (en) * 2002-05-17 2008-11-25 Sequella, Inc. Anti tubercular drug: compositions and methods
US20040033986A1 (en) * 2002-05-17 2004-02-19 Protopopova Marina Nikolaevna Anti tubercular drug: compositions and methods
CN101404986B (zh) * 2002-05-17 2011-09-28 赛奎拉公司 用于诊断和治疗感染性疾病的组合物和制药方法
WO2005034857A2 (en) * 2003-09-05 2005-04-21 Sequella, Inc. Methods and compositions comprising diamines as new anti-tubercular therapeutics
US20090281054A1 (en) * 2008-05-06 2009-11-12 Venkata Reddy Compositions and methods comprising capuramycin analogues
KR101104505B1 (ko) * 2010-01-30 2012-01-12 김근섭 호스 연결용 원클릭 피팅
WO2015027137A1 (en) * 2013-08-23 2015-02-26 University Of Tennessee Research Foundation Improved synthesis of capuramycin and its analogues
WO2022006231A1 (en) * 2020-06-30 2022-01-06 University Of Tennessee Research Foundation Dpagt1 inhibitors of capuramycin analogues and their antimigratory activities of solid tumors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60259190A (ja) * 1984-06-06 1985-12-21 Kanto Ishi Pharma Co Ltd 新抗生物質カプラマイシン及びその製造法
US5034381A (en) 1988-01-07 1991-07-23 Ciba-Geigy Corporation 2-(substituted amino) adenosines as antihypertensives
JPH05148293A (ja) * 1991-11-28 1993-06-15 Mect Corp 新規カプラマイシン誘導体およびその製造方法
GB9307043D0 (en) 1993-04-05 1993-05-26 Norsk Hydro As Chemical compounds
JP4428762B2 (ja) 1998-07-09 2010-03-10 セケラ インコーポレイテッド 抗生物質ａ−５００３５９及び誘導体
CN1181087C (zh) * 1998-07-09 2004-12-22 三共株式会社 新的抗菌化合物
JP4531167B2 (ja) 1998-09-24 2010-08-25 セケラ インコーポレイテッド 新規抗細菌化合物
JP5022539B2 (ja) 2000-01-07 2012-09-12 セケラ インコーポレイテッド 抗生物質ａ−５００３５９及び誘導体を含有する抗菌剤
JP4960548B2 (ja) * 2000-01-07 2012-06-27 セケラ インコーポレイテッド 新規抗細菌化合物の用途

Also Published As

Publication number Publication date
HUP0204217A2 (en) 2003-03-28
KR20020092901A (ko) 2002-12-12
EP1209166A4 (en) 2002-10-09
ZA200201409B (en) 2003-07-30
HUP0204217A3 (en) 2005-11-28
TR200200485T2 (tr) 2002-06-21
IL148196A (en) 2008-06-05
AU6595500A (en) 2001-03-19
IL148196A0 (en) 2002-09-12
EP1209166A1 (en) 2002-05-29
TWI245047B (en) 2005-12-11
NO323556B1 (no) 2007-06-11
NO20020804L (no) 2002-04-19
CA2382654A1 (en) 2001-03-01
US7157442B2 (en) 2007-01-02
NZ517315A (en) 2004-02-27
EP1209166B1 (en) 2004-03-31
CN1382152A (zh) 2002-11-27
CZ2002682A3 (cs) 2002-06-12
PT1209166E (pt) 2004-06-30
CN1176936C (zh) 2004-11-24
DE60009517D1 (de) 2004-05-06
NO20020804D0 (no) 2002-02-19
ATE263183T1 (de) 2004-04-15
MXPA02001817A (es) 2002-08-12
BR0013435A (pt) 2002-07-16
DE60009517T2 (de) 2005-01-13
CA2382654C (en) 2009-01-13
WO2001014399A1 (fr) 2001-03-01
AU763492B2 (en) 2003-07-24
US20030171330A1 (en) 2003-09-11
ES2216933T3 (es) 2004-11-01
KR100787849B1 (ko) 2007-12-27
HK1044951A1 (en) 2002-11-08
PL353494A1 (en) 2003-11-17
RU2227799C2 (ru) 2004-04-27

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