TR200200485T2 - Yeni A-500359 türevleri. - Google Patents

Yeni A-500359 türevleri.

Info

Publication number
TR200200485T2
TR200200485T2 TR2002/00485T TR200200485T TR200200485T2 TR 200200485 T2 TR200200485 T2 TR 200200485T2 TR 2002/00485 T TR2002/00485 T TR 2002/00485T TR 200200485 T TR200200485 T TR 200200485T TR 200200485 T2 TR200200485 T2 TR 200200485T2
Authority
TR
Turkey
Prior art keywords
bacterial infections
derivatives
salts
compositions
optionally substituted
Prior art date
Application number
TR2002/00485T
Other languages
English (en)
Inventor
Hotoda Hitoshi
Kaneko Masakatsu
Inukai Masatoshi
Muramatsu Yasunori
Utsui Yukio
Ohya Satoshi
Original Assignee
Sankyo Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Company Limited filed Critical Sankyo Company Limited
Publication of TR200200485T2 publication Critical patent/TR200200485T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/067—Pyrimidine radicals with ribosyl as the saccharide radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)

Abstract

Genel formül (I) bilesimleri veya farmakolojik olarak kabul edilebilir türevleri veya tuzlari;bakteriyal enfeksiyonlarin önlenmesi veya tedavisi için,aktif madde olarak bilesimleri,türevleri veya tuzlari içeren terkipler; bu terkiplerin, bakteriyal enfeksiyonlar için önleyici veya terapötik ilaç yapiminda kullanim; ve bunlarin farmakolojik olarak etkili dozlarda sicak kanli hayvanlara verilmesini içeren, bakteriyal enfeksiyonlar için önleyici veya terapötik yöntemler; Genel formül (I)'de, her bir R1 ve R2 tercihe göre ikameli bir aril, heterosiklik,alkil, veya alkenil, vs; R3 hidroksil; ve her bir X1 ve X2, oksijen, sülfür veya tercihe göre ikameli nitrojendir.
TR2002/00485T 1999-08-20 2000-08-18 Yeni A-500359 türevleri. TR200200485T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP23393499 1999-08-20

Publications (1)

Publication Number Publication Date
TR200200485T2 true TR200200485T2 (tr) 2002-06-21

Family

ID=16962911

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/00485T TR200200485T2 (tr) 1999-08-20 2000-08-18 Yeni A-500359 türevleri.

Country Status (25)

Country Link
US (1) US7157442B2 (tr)
EP (1) EP1209166B1 (tr)
KR (1) KR100787849B1 (tr)
CN (1) CN1176936C (tr)
AT (1) ATE263183T1 (tr)
AU (1) AU763492B2 (tr)
BR (1) BR0013435A (tr)
CA (1) CA2382654C (tr)
CZ (1) CZ2002682A3 (tr)
DE (1) DE60009517T2 (tr)
DK (1) DK1209166T3 (tr)
ES (1) ES2216933T3 (tr)
HK (1) HK1044951A1 (tr)
HU (1) HUP0204217A3 (tr)
IL (2) IL148196A0 (tr)
MX (1) MXPA02001817A (tr)
NO (1) NO323556B1 (tr)
NZ (1) NZ517315A (tr)
PL (1) PL353494A1 (tr)
PT (1) PT1209166E (tr)
RU (1) RU2227799C2 (tr)
TR (1) TR200200485T2 (tr)
TW (1) TWI245047B (tr)
WO (1) WO2001014399A1 (tr)
ZA (1) ZA200201409B (tr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID27955A (id) * 1998-07-09 2001-05-03 Sankyo Co Senyawa-senyawa antimikroba yang baru
US7456222B2 (en) * 2002-05-17 2008-11-25 Sequella, Inc. Anti tubercular drug: compositions and methods
US20040033986A1 (en) * 2002-05-17 2004-02-19 Protopopova Marina Nikolaevna Anti tubercular drug: compositions and methods
US7652039B2 (en) * 2002-05-17 2010-01-26 Sequella, Inc. Methods of use and compositions for the diagnosis and treatment of infectious disease
WO2005034857A2 (en) * 2003-09-05 2005-04-21 Sequella, Inc. Methods and compositions comprising diamines as new anti-tubercular therapeutics
US20090281054A1 (en) * 2008-05-06 2009-11-12 Venkata Reddy Compositions and methods comprising capuramycin analogues
KR101104505B1 (ko) * 2010-01-30 2012-01-12 김근섭 호스 연결용 원클릭 피팅
WO2015027137A1 (en) * 2013-08-23 2015-02-26 University Of Tennessee Research Foundation Improved synthesis of capuramycin and its analogues
WO2022006231A1 (en) * 2020-06-30 2022-01-06 University Of Tennessee Research Foundation Dpagt1 inhibitors of capuramycin analogues and their antimigratory activities of solid tumors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60259190A (ja) * 1984-06-06 1985-12-21 Kanto Ishi Pharma Co Ltd 新抗生物質カプラマイシン及びその製造法
US5034381A (en) * 1988-01-07 1991-07-23 Ciba-Geigy Corporation 2-(substituted amino) adenosines as antihypertensives
JPH05148293A (ja) * 1991-11-28 1993-06-15 Mect Corp 新規カプラマイシン誘導体およびその製造方法
GB9307043D0 (en) 1993-04-05 1993-05-26 Norsk Hydro As Chemical compounds
ID27955A (id) * 1998-07-09 2001-05-03 Sankyo Co Senyawa-senyawa antimikroba yang baru
JP4428762B2 (ja) 1998-07-09 2010-03-10 セケラ インコーポレイテッド 抗生物質ａ−５００３５９及び誘導体
JP4531167B2 (ja) 1998-09-24 2010-08-25 セケラ インコーポレイテッド 新規抗細菌化合物
JP5022539B2 (ja) 2000-01-07 2012-09-12 セケラ インコーポレイテッド 抗生物質ａ−５００３５９及び誘導体を含有する抗菌剤
JP4960548B2 (ja) * 2000-01-07 2012-06-27 セケラ インコーポレイテッド 新規抗細菌化合物の用途

Also Published As

Publication number Publication date
ATE263183T1 (de) 2004-04-15
WO2001014399A1 (fr) 2001-03-01
NO323556B1 (no) 2007-06-11
DE60009517D1 (de) 2004-05-06
RU2227799C2 (ru) 2004-04-27
EP1209166A4 (en) 2002-10-09
IL148196A0 (en) 2002-09-12
EP1209166B1 (en) 2004-03-31
MXPA02001817A (es) 2002-08-12
TWI245047B (en) 2005-12-11
AU763492B2 (en) 2003-07-24
HUP0204217A3 (en) 2005-11-28
ZA200201409B (en) 2003-07-30
DK1209166T3 (da) 2004-07-26
CA2382654A1 (en) 2001-03-01
NO20020804D0 (no) 2002-02-19
IL148196A (en) 2008-06-05
CZ2002682A3 (cs) 2002-06-12
US20030171330A1 (en) 2003-09-11
ES2216933T3 (es) 2004-11-01
HK1044951A1 (en) 2002-11-08
KR100787849B1 (ko) 2007-12-27
NZ517315A (en) 2004-02-27
PT1209166E (pt) 2004-06-30
KR20020092901A (ko) 2002-12-12
PL353494A1 (en) 2003-11-17
AU6595500A (en) 2001-03-19
NO20020804L (no) 2002-04-19
DE60009517T2 (de) 2005-01-13
BR0013435A (pt) 2002-07-16
EP1209166A1 (en) 2002-05-29
CN1176936C (zh) 2004-11-24
CA2382654C (en) 2009-01-13
CN1382152A (zh) 2002-11-27
HUP0204217A2 (en) 2003-03-28
US7157442B2 (en) 2007-01-02

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