DK1198224T3 - Formuleringer til opløsninger af steroider til indgivelse via inhalering - Google Patents

Formuleringer til opløsninger af steroider til indgivelse via inhalering

Info

Publication number
DK1198224T3
DK1198224T3 DK00956216T DK00956216T DK1198224T3 DK 1198224 T3 DK1198224 T3 DK 1198224T3 DK 00956216 T DK00956216 T DK 00956216T DK 00956216 T DK00956216 T DK 00956216T DK 1198224 T3 DK1198224 T3 DK 1198224T3
Authority
DK
Denmark
Prior art keywords
formulations
inhalation administration
steroid solutions
relates
solutions
Prior art date
Application number
DK00956216T
Other languages
Danish (da)
English (en)
Inventor
Chiara Malvolti
Raffaella Garzia
Gaetano Brambilla
Paolo Chiesi
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Application granted granted Critical
Publication of DK1198224T3 publication Critical patent/DK1198224T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
DK00956216T 1999-07-23 2000-07-20 Formuleringer til opløsninger af steroider til indgivelse via inhalering DK1198224T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI001625A IT1313553B1 (it) 1999-07-23 1999-07-23 Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
PCT/EP2000/006916 WO2001007014A1 (en) 1999-07-23 2000-07-20 Formulations of steroid solutions for inhalatory administration

Publications (1)

Publication Number Publication Date
DK1198224T3 true DK1198224T3 (da) 2003-09-29

Family

ID=11383393

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00956216T DK1198224T3 (da) 1999-07-23 2000-07-20 Formuleringer til opløsninger af steroider til indgivelse via inhalering

Country Status (14)

Country Link
US (1) US6967017B1 (cs)
EP (1) EP1198224B1 (cs)
AT (1) ATE241959T1 (cs)
AU (1) AU6825000A (cs)
CZ (1) CZ299071B6 (cs)
DE (1) DE60003183T2 (cs)
DK (1) DK1198224T3 (cs)
ES (1) ES2200913T3 (cs)
HU (1) HUP0201956A3 (cs)
IT (1) IT1313553B1 (cs)
NO (1) NO20020342D0 (cs)
PL (1) PL198817B1 (cs)
PT (1) PT1198224E (cs)
WO (1) WO2001007014A1 (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20010614A1 (it) * 2001-10-16 2003-04-16 Italchimici S P A Preparazione farmaceutica di una soluzione idro/propilenica di budesonide e suo procedimento di preparazione.
US20040265238A1 (en) * 2003-06-27 2004-12-30 Imtiaz Chaudry Inhalable formulations for treating pulmonary hypertension and methods of using same
ITMI20032054A1 (it) 2003-10-22 2005-04-23 Monteres S R L Processo per la preparazione di sospensioni farmaceutiche da inalare.
AR041873A1 (es) * 2003-10-30 2005-06-01 Pablo Cassara Srl Lab Una formulacion farmaceutica en aerosol adecuada para la inhalacion oral o nasal que contienen glucocorticoides en solucion estable al almacenamiento; un metodo para estabilzar formulaciones y uso de un agente estabilizante
PE20050941A1 (es) * 2003-12-16 2005-11-08 Nycomed Gmbh Suspensiones acuosas de ciclesonida para nebulizacion
ITRM20040268A1 (it) * 2004-05-31 2004-08-31 Italchimici S P A Formulazione farmaceutica di una soluzione stabile di formoterolo per via inalatoria e suo precedimento di preparazione.
JP5259193B2 (ja) * 2005-02-25 2013-08-07 チエシイ・ファルマセウテイシイ・エス・ペー・アー 加圧下にある用量計量型吸入器用の金属イオン封鎖剤を含む薬用エーロゾル配合物
GB0604141D0 (en) * 2006-03-01 2006-04-12 Arrow Int Ltd Nebulizer formulation
CZ302596B6 (cs) * 2007-04-12 2011-07-27 Jihoceská univerzita v Ceských Budejovicích, Zemedelská fakulta Zpusob zpracování biomasy jetele lucního

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3361306A (en) 1966-03-31 1968-01-02 Merck & Co Inc Aerosol unit dispensing uniform amounts of a medically active ingredient
US3622053A (en) 1969-12-10 1971-11-23 Schering Corp Aerosol inhaler with flip-up nozzle
MX3864E (es) 1975-05-27 1981-08-26 Syntex Corp Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona
US4185100A (en) 1976-05-13 1980-01-22 Johnson & Johnson Topical anti-inflammatory drug therapy
US4499108A (en) 1983-06-08 1985-02-12 Schering Corporation Stable pleasant-tasting albuterol sulfate pharmaceutical formulations
IT1196142B (it) 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
US5192528A (en) 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
US5225183A (en) 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
GB8828477D0 (en) 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
IE67185B1 (en) 1990-02-02 1996-03-06 Fisons Plc Propellant compositions
WO1992011236A1 (en) 1990-12-19 1992-07-09 Smithkline Beecham Corporation Aerosol formulations
US6006745A (en) 1990-12-21 1999-12-28 Minnesota Mining And Manufacturing Company Device for delivering an aerosol
EP0504112A3 (en) 1991-03-14 1993-04-21 Ciba-Geigy Ag Pharmaceutical aerosol formulations
JP3327546B2 (ja) 1991-05-21 2002-09-24 アボツト・ラボラトリーズ エアゾール吸入装置
EP0601036B1 (de) 1991-08-29 1999-04-28 Broncho-Air Medizintechnik AG Medizinisches gerät zur inhalation von dosier-aerosolen
IL103238A (en) 1991-09-25 1995-07-31 Fisons Plc Pressurised aerosol compositions
IL104068A (en) 1991-12-12 1998-10-30 Glaxo Group Ltd Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant
ATE150296T1 (de) 1991-12-18 1997-04-15 Minnesota Mining & Mfg Aerosolzusammensetzungen für arzneimittelsuspensionen
DE4230876A1 (de) 1992-03-17 1993-09-23 Asta Medica Ag Druckgaspackungen unter verwendung von polyoxyethylen-glyceryl-oleaten
BR9307627A (pt) 1992-12-09 1999-06-15 Boehringer Ingelheim Pharma Formulações mediciais estabilizadas em solução aerosol
SE9203743D0 (sv) 1992-12-11 1992-12-11 Astra Ab Efficient use
AU4066693A (en) 1992-12-23 1994-07-19 Bernhard Hugemann Compacted drug body for use in the mechanical generation of inhalable active-substance particles
DE69405719T2 (de) 1993-03-17 1998-01-15 Minnesota Mining & Mfg Aerosolzubereitung, enthaltend ein aus einem diol-disäure-derivat abgeleitetes dispergiermittel
US5569450A (en) 1993-03-17 1996-10-29 Minnesota Mining And Manufacturing Company Aerosol formulation containing an ester-, amide-, or mercaptoester-derived dispersing aid
US6596260B1 (en) 1993-08-27 2003-07-22 Novartis Corporation Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol
DK0735884T3 (da) 1993-12-20 2000-10-09 Minnesota Mining & Mfg Flunisolid-aerosolformuleringer
GB9425160D0 (en) 1994-12-10 1995-02-08 Glaxo Group Ltd Medicaments
CN1088580C (zh) 1994-12-22 2002-08-07 阿斯特拉公司 气溶胶药物制剂
GB9426252D0 (en) 1994-12-24 1995-02-22 Glaxo Group Ltd Pharmaceutical composition
DE4446891A1 (de) * 1994-12-27 1996-07-04 Falk Pharma Gmbh Stabile wäßrige Budesonid-Lösung
US5653961A (en) 1995-03-31 1997-08-05 Minnesota Mining And Manufacturing Company Butixocort aerosol formulations in hydrofluorocarbon propellant
AP791A (en) 1995-04-14 1999-12-17 Glaxo Wellcome Inc Metered dose inhaler for albuterol.
DK1166811T3 (da) 1995-04-14 2007-03-12 Smithkline Beecham Corp Dosisudmålende inhalator til fluticasonpropionat
TR199701170T1 (xx) 1995-04-14 1998-02-21 Glaxo Wellcome Inc. Beklometazon dipropionat i�in �l��lm�� doz inhaleri.
KR100403899B1 (ko) 1995-04-14 2004-03-20 글락소 웰컴 인크. 살메테롤용정량흡입기
GB9612297D0 (en) 1996-06-11 1996-08-14 Minnesota Mining & Mfg Medicinal aerosol formulations
EP0914143A1 (en) 1996-07-08 1999-05-12 Rhone-Poulenc Rorer Limited Medicinal cyclosporin-a aerosol solution formulation
AU3811897A (en) 1996-07-24 1998-02-10 Oglios Therapeutics, Inc. Antisense oligonucleotides as antibacterial agents
GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
GB9620187D0 (en) 1996-09-27 1996-11-13 Minnesota Mining & Mfg Medicinal aerosol formulations
EP1011646B1 (en) 1996-12-04 2005-08-17 Link Products Limited Pharmaceutical compositions and devices for their administration
US6413496B1 (en) 1996-12-04 2002-07-02 Biogland Ireland (R&D) Limited Pharmaceutical compositions and devices for their administration
WO1998034595A1 (de) 1997-02-05 1998-08-13 Jago Research Ag Medizinische aerosolformulierungen
US6126919A (en) 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
US5891419A (en) 1997-04-21 1999-04-06 Aeropharm Technology Limited Environmentally safe flunisolide aerosol formulations for oral inhalation
GB2326334A (en) 1997-06-13 1998-12-23 Chiesi Farma Spa Pharmaceutical aerosol compositions
US20010031244A1 (en) 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
BR7702049U (pt) 1997-09-05 1999-09-14 Chiesi Farma Spa Bico pulverizador para utilização em inalador oral para medicamentos aerossóis
NZ504021A (en) 1997-10-17 2003-04-29 Systemic Pulmonary Delivery Lt Method and apparatus for delivering aerosolized medication having air discharged through air tube directly into plume of aerosolized medication
US6045784A (en) 1998-05-07 2000-04-04 The Procter & Gamble Company Aerosol package compositions containing fluorinated hydrocarbon propellants
SE9802073D0 (sv) 1998-06-11 1998-06-11 Astra Ab New use
NZ509418A (en) 1998-06-18 2003-06-30 Boehringer Ingelheim Pharma Pharmaceutical formulations for aerosols with two or more active substances
US6451285B2 (en) 1998-06-19 2002-09-17 Baker Norton Pharmaceuticals, Inc. Suspension aerosol formulations containing formoterol fumarate and a fluoroalkane propellant
US6241969B1 (en) * 1998-06-26 2001-06-05 Elan Corporation Plc Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
JP4570251B2 (ja) 1998-07-24 2010-10-27 ヤゴテック アーゲー 医薬用エーロゾル製剤
US6475467B1 (en) 1998-08-04 2002-11-05 Jago Research Ag Medicinal aerosol formulations
DE19847969A1 (de) 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Lagerfähig flüssige Formulierung mit Formoterol
ES2178479T3 (es) 1998-10-17 2002-12-16 Boehringer Ingelheim Pharma Concentrado de principio activo con formoterol, apto para el almacenamiento.
PT1131059E (pt) 1998-11-13 2003-07-31 Jago Res Ag Po seco para inalacao
IT1303788B1 (it) 1998-11-25 2001-02-23 Chiesi Farma Spa Formulazioni di aerosol medicinali.
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US6004537A (en) * 1998-12-18 1999-12-21 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol
US6290930B1 (en) 1998-12-18 2001-09-18 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes and budesonide
AU3409399A (en) 1999-03-05 2000-09-28 Chiesi Farmaceutici S.P.A. Improved powdery pharmaceutical compositions for inhalation
US6315985B1 (en) 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
WO2001047493A1 (en) 1999-12-24 2001-07-05 Glaxo Group Limited Pharmaceutical aerosol formulation of salmeterol and fluticasone propionate
IT1317846B1 (it) 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
IT1318514B1 (it) 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
AU2000250701B2 (en) 2000-05-22 2004-07-01 Chiesi Farmaceutici S.P.A. Stable pharmaceutical solution formulations for pressurised metered dose inhalers

Also Published As

Publication number Publication date
CZ2002257A3 (cs) 2002-05-15
EP1198224B1 (en) 2003-06-04
PT1198224E (pt) 2003-10-31
DE60003183D1 (de) 2003-07-10
PL198817B1 (pl) 2008-07-31
IT1313553B1 (it) 2002-09-09
ITMI991625A0 (it) 1999-07-23
EP1198224A1 (en) 2002-04-24
ES2200913T3 (es) 2004-03-16
AU6825000A (en) 2001-02-13
ITMI991625A1 (it) 2001-01-23
WO2001007014A1 (en) 2001-02-01
US6967017B1 (en) 2005-11-22
CZ299071B6 (cs) 2008-04-16
NO20020342L (no) 2002-01-22
HUP0201956A2 (en) 2002-10-28
DE60003183T2 (de) 2004-04-29
PL353470A1 (en) 2003-11-17
HUP0201956A3 (en) 2003-10-28
ATE241959T1 (de) 2003-06-15
NO20020342D0 (no) 2002-01-22

Similar Documents

Publication Publication Date Title
WO2005065185A3 (en) Temperature-stable formulations, and methods of development thereof
JP4603687B2 (ja) 点鼻用液剤
WO2005004895A3 (en) Compositions and methods for enhanced mucosal delivery of growth hormone
SE0102276D0 (sv) Device and method for the administration of a medicament
DE60120648D1 (de) Formulierungen von copolymer 1 (glatirameracetat) zur oralen, nasalen und pulmonalen verabreichung
ATE299740T1 (de) Kombination aus einem no-donor und einem antioxidans zur behanndlung sexueller störungen
AU2001296865A1 (en) (5-(2-hydroxy-4-chlorobenzoyl) aminovaleric acid and salts thereof and compositions containing the same for delivering active agents
WO2005044226A3 (en) Lipid formulations for spontaneous drug encapsulation
WO2003079993A3 (en) hGH (HUMAN GROWTH HORMONE) FORMULATIONS FOR PULMONARY ADMINISTRATION
DK1198224T3 (da) Formuleringer til opløsninger af steroider til indgivelse via inhalering
MA27702A1 (fr) Preparation de suspensions aqueuses steriles comprenant des ingredients actifs cristallins micronises, destinees a l'inhalation
DK1280558T3 (da) Halvfast indgivelsesvehikel og farmaceutiske sammensætninger
NO20023875L (no) Stabilt nasalt, oralt eller sublingualt anvendbart preparat
WO2001047913A3 (de) Substituierte n-benzyl-indol-3-yl- glyoxylsäure-derivate antitumorwirkung
PE20011223A1 (es) Composicion farmaceutica que comprende pemetrexed y un antioxidante como monotioglicerol, l-cisteina y acido tioglicolico
DK1673074T3 (da) Flydende præparat, indeholdende tobramycin
ATE311928T1 (de) (-)-pseudoephedrin als sympathomimetisches arzneimittel
DK1343472T3 (da) Thixotropisk næsespray
NZ537186A (en) Nasal compositions comprising a mucopolysaccharide and propylene glycol
UY25510A1 (es) Procedimiento para la producción de preparados efervescentes
JPH11147825A (ja) 粘膜吸収性の向上方法及び粘膜外用剤
Bose et al. Lidocaine in bronchoscopy: Practical use and allergic reactions
NO20013605D0 (no) Preparat for vorter
WO2004033484A3 (en) Use of stable glutamine derivatives to improve drug absorption
AU2001258859A1 (en) Pralmorelin-containing nasal drop preparations