DK119052B - Analogifremgangsmåde til fremstilling af benzensulfonylurinstoffer eller salte deraf. - Google Patents
Analogifremgangsmåde til fremstilling af benzensulfonylurinstoffer eller salte deraf.Info
- Publication number
- DK119052B DK119052B DK506164AA DK506164A DK119052B DK 119052 B DK119052 B DK 119052B DK 506164A A DK506164A A DK 506164AA DK 506164 A DK506164 A DK 506164A DK 119052 B DK119052 B DK 119052B
- Authority
- DK
- Denmark
- Prior art keywords
- benzenesulfonylureas
- salts
- preparation
- analogous process
- analogous
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
- C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
- C07C311/59—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/22—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF41042A DE1185180B (de) | 1963-10-19 | 1963-10-19 | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
| DEF0042062 | 1964-02-20 | ||
| DEF0042933 | 1964-05-21 | ||
| DEF0043268 | 1964-06-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK119052B true DK119052B (da) | 1970-11-09 |
Family
ID=27436911
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK506164AA DK119052B (da) | 1963-10-19 | 1964-10-14 | Analogifremgangsmåde til fremstilling af benzensulfonylurinstoffer eller salte deraf. |
| DK541765AA DK120742B (da) | 1963-10-19 | 1965-10-22 | Analogifremgangsmåde til fremstilling af benzensulfonylurinstoffer eller salte deraf. |
| DK541665AA DK119455B (da) | 1963-10-19 | 1965-10-22 | Analogifremgangsmåde til fremstilling af benzensulfonylurinstoffer eller salte deraf. |
| DK541865AA DK119105B (da) | 1963-10-19 | 1965-10-22 | Analogifremgangsmåde til fremstilling af benzensulfonylurinstoffer eller salte deraf. |
| DK541565AA DK120741B (da) | 1963-10-19 | 1965-10-22 | Analogifremgangsmåde til fremstilling af benzensulfonyluringstoffer eller salte deraf. |
| DK541965AA DK120534B (da) | 1963-10-19 | 1965-10-22 | Analogifremgangsmåde til fremstilling af benzen sulfonylurinstoffer eller salte deraf. |
| DK542065AA DK120588B (da) | 1963-10-19 | 1965-10-22 | Analogifremgangsmåde til fremstilling af benzensulfonylurinstoffer eller salte deraf. |
Family Applications After (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK541765AA DK120742B (da) | 1963-10-19 | 1965-10-22 | Analogifremgangsmåde til fremstilling af benzensulfonylurinstoffer eller salte deraf. |
| DK541665AA DK119455B (da) | 1963-10-19 | 1965-10-22 | Analogifremgangsmåde til fremstilling af benzensulfonylurinstoffer eller salte deraf. |
| DK541865AA DK119105B (da) | 1963-10-19 | 1965-10-22 | Analogifremgangsmåde til fremstilling af benzensulfonylurinstoffer eller salte deraf. |
| DK541565AA DK120741B (da) | 1963-10-19 | 1965-10-22 | Analogifremgangsmåde til fremstilling af benzensulfonyluringstoffer eller salte deraf. |
| DK541965AA DK120534B (da) | 1963-10-19 | 1965-10-22 | Analogifremgangsmåde til fremstilling af benzen sulfonylurinstoffer eller salte deraf. |
| DK542065AA DK120588B (da) | 1963-10-19 | 1965-10-22 | Analogifremgangsmåde til fremstilling af benzensulfonylurinstoffer eller salte deraf. |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US3426067A (da) |
| AT (5) | AT262308B (da) |
| BE (1) | BE654561A (da) |
| CH (1) | CH529115A (da) |
| CY (1) | CY436A (da) |
| DE (1) | DE1185180B (da) |
| DK (7) | DK119052B (da) |
| ES (1) | ES312472A1 (da) |
| FI (1) | FI44597B (da) |
| FR (2) | FR1473834A (da) |
| GB (1) | GB1080705A (da) |
| IL (1) | IL22259A (da) |
| IS (1) | IS765B6 (da) |
| IT (1) | IT1061504B (da) |
| LU (1) | LU47099A1 (da) |
| MC (1) | MC488A1 (da) |
| MY (1) | MY6800113A (da) |
| NL (1) | NL6412137A (da) |
| NO (1) | NO118548B (da) |
| OA (1) | OA01367A (da) |
| SE (8) | SE311151B (da) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1185180B (de) * | 1963-10-19 | 1965-01-14 | Hoechst Ag | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
| DE1493672C3 (de) * | 1964-08-01 | 1974-05-02 | Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
| DE1443905C3 (de) * | 1964-10-30 | 1979-03-15 | Hoechst Ag, 6000 Frankfurt | benzolsulfonyl] -N'-cyclohexylharnstoff, Verfahren zu seiner Herstellung und seine Verwendung |
| DE1518816C3 (de) * | 1965-03-24 | 1975-05-22 | Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt | Benzolsulfonylharnstoffe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate |
| US4066639A (en) * | 1965-05-06 | 1978-01-03 | Hoechst Aktiengesellschaft | Benzene-sulfonyl semicarbazides and process for preparing them |
| DE1518895C3 (de) * | 1965-12-02 | 1978-12-07 | Hoechst Ag, 6000 Frankfurt | Benzolsulfonylharnstoffe, Verfahren zu ihrer Herstellung und deren Verwendung |
| US3454635A (en) * | 1965-07-27 | 1969-07-08 | Hoechst Ag | Benzenesulfonyl-ureas and process for their manufacture |
| DE1244174C2 (de) * | 1965-09-10 | 1968-01-18 | Hoechst Ag | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
| US3932503A (en) * | 1966-05-28 | 1976-01-13 | Hoechst Aktiengesellschaft | Benzenesulfonyl ureas |
| US3932658A (en) * | 1969-02-25 | 1976-01-13 | Hoechst Aktiengesellschaft | Composition and method for lower blood sugar containing N-[4-(β-<2-methoxy-5-chloro-benzamido>-ethyl)-benzenesulfonyl]-N'-cyclopentyl-urea |
| NL138933B (nl) * | 1969-03-26 | 1973-05-15 | Erba Carlo Spa | Werkwijze voor het bereiden van benzeensulfonylureumderivaten met bloedsuikerspiegelverlagende werking. |
| BE754454A (fr) * | 1969-08-06 | 1971-02-05 | Bayer Ag | Nouveaux composes hypoglycemiques du type d'arylsulfonylurees et d'arylsulfonylsemicarbazides contenant des groupes carbonamide |
| US3957866A (en) * | 1970-09-23 | 1976-05-18 | J. Uriach & Cia S.A. | Cyclopentyl carbamide derivative and process for its production |
| ES384463A1 (es) * | 1970-09-23 | 1973-10-01 | Uriach & Cia Sa J | Procedimiento para la obtencion de n-4 - (beta-o-anisamido etil) - bencenosulfonil - n'ciclopentilcarbamida. |
| US4072758A (en) * | 1970-09-23 | 1978-02-07 | J. Uriach Y Cia, S.A. | Compositions and methods for effecting glucoreduction |
| BE791638A (fr) * | 1971-11-20 | 1973-05-21 | Hoechst Ag | Sulfonyl-urees, leur procede de preparation et leurs applications |
| DE2230543A1 (de) * | 1972-06-22 | 1974-01-17 | Hoechst Ag | Benzolsulfonylharnstoffe und verfahren zu ihrer herstellung |
| US4067998A (en) * | 1974-02-11 | 1978-01-10 | The Dow Chemical Company | 2-((3,5-Di-tert-butylphenyl)thio) alkanoic acids and derivatives |
| DE2413514C3 (de) * | 1974-03-21 | 1982-03-04 | Hoechst Ag, 6000 Frankfurt | N-Acylaminoathylbenzolsulfonyl-N'-methylharnstoffe, Verfahren zu ihrer Herstellung und deren Verwendung |
| AU528362B2 (en) * | 1978-06-22 | 1983-04-28 | Societe D:Etudes De Produits Chimiques | Phenoxy isobutyramides |
| DE3211934A1 (de) * | 1982-03-31 | 1983-10-13 | Hoechst Ag, 6230 Frankfurt | Salicylsaeurederivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung |
| US4916163A (en) * | 1985-06-04 | 1990-04-10 | The Upjohn Company | Spray-dried lactose formulation of micronized glyburide |
| ES2098069T3 (es) * | 1993-02-23 | 1997-04-16 | Hoechst Ag | Bencenosulfonil-ureas y -tioureas sustituidas, procedimiento para su preparacion y su utilizacion como agentes farmaceuticos. |
| HU226462B1 (en) * | 1995-02-17 | 2008-12-29 | Hoechst Ag | Substituted benzol-sulfonyl-ureas and -thioureas, process for producing them, pharmaceutical compositions containing them, and their use |
| KR100981592B1 (ko) * | 1998-09-10 | 2010-09-13 | 사노피-아벤티스 도이칠란트 게엠베하 | 벤젠설포닐(티오)우레아 또는 베타-수용체 차단제와 배합된 벤젠설포닐(티오)우레아를 포함하는 자율신경계 기능부전의 치료 또는 예방을 위한 약제학적 조성물 |
| DE19923086A1 (de) | 1999-05-20 | 2000-11-23 | Aventis Pharma Gmbh | Cinnamoylaminoalkyl-substituierte Benzolsulfonamidderivate, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| US20010036479A1 (en) | 2000-01-14 | 2001-11-01 | Gillian Cave | Glyburide composition |
| DE10054481A1 (de) | 2000-11-03 | 2002-05-08 | Aventis Pharma Gmbh | Acylaminoalkyl-substituierte Benzolsulfonamidderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| DE10054482A1 (de) | 2000-11-03 | 2002-05-08 | Aventis Pharma Gmbh | Heteroarylacryloylaminoalkyl-substituierte Benzolsulfonamidderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| JP2005522495A (ja) * | 2002-04-11 | 2005-07-28 | カルボマー インク | 新規な糖尿病イメージングプローブ |
| US20060201981A1 (en) * | 2003-06-30 | 2006-09-14 | Meyer Dean E | Clip support member for golf bag |
| CA2611376C (en) * | 2005-06-13 | 2013-09-10 | Merck Sharp & Dohme Limited | Therapeutic agents |
| WO2010048287A2 (en) | 2008-10-22 | 2010-04-29 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Radioprotective agents |
| WO2012079164A1 (en) * | 2010-12-16 | 2012-06-21 | The Governing Council Of The University Of Toronto | Activators of cylindrical proteases |
| AU2017416068A1 (en) | 2017-05-24 | 2019-10-31 | The Provost, Fellows, Foundation Scholars, And Other Members Of Board, Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | Novel compounds and uses |
| CN112979571B (zh) * | 2021-02-24 | 2023-01-31 | 中国药科大学 | 一类akr1c3选择性抑制剂及其制备方法与用途 |
| EP4341246A1 (en) * | 2021-05-17 | 2024-03-27 | The United States of America, as represented by The Secretary, Department of Health and Human Services | A facile and odor-free approach to convert sulfonyl urea derivatives to chalcogenide sulfonyl urea derivatives |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL218580A (da) * | 1960-04-28 | |||
| DE1185180B (de) * | 1963-10-19 | 1965-01-14 | Hoechst Ag | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
-
1963
- 1963-10-19 DE DEF41042A patent/DE1185180B/de active Pending
-
1964
- 1964-10-07 LU LU47099A patent/LU47099A1/xx unknown
- 1964-10-13 US US403641A patent/US3426067A/en not_active Expired - Lifetime
- 1964-10-14 IL IL22259A patent/IL22259A/xx unknown
- 1964-10-14 DK DK506164AA patent/DK119052B/da unknown
- 1964-10-16 AT AT115067A patent/AT262308B/de active
- 1964-10-16 AT AT881464A patent/AT261627B/de active
- 1964-10-16 SE SE12459/64A patent/SE311151B/xx unknown
- 1964-10-16 CH CH1347664A patent/CH529115A/de not_active IP Right Cessation
- 1964-10-16 AT AT01149/67A patent/AT278027B/de not_active IP Right Cessation
- 1964-10-16 IS IS1424A patent/IS765B6/is unknown
- 1964-10-16 AT AT114867A patent/AT267541B/de active
- 1964-10-16 AT AT115167A patent/AT262309B/de active
- 1964-10-17 NO NO155188A patent/NO118548B/no unknown
- 1964-10-19 FR FR991866A patent/FR1473834A/fr not_active Expired
- 1964-10-19 GB GB42547/64A patent/GB1080705A/en not_active Expired
- 1964-10-19 NL NL6412137A patent/NL6412137A/xx unknown
- 1964-10-19 BE BE654561A patent/BE654561A/xx unknown
- 1964-10-19 IT IT22418/64A patent/IT1061504B/it active
- 1964-10-19 MC MC515A patent/MC488A1/xx unknown
- 1964-10-19 FI FI2196/64A patent/FI44597B/fi active
- 1964-12-31 OA OA51813A patent/OA01367A/xx unknown
-
1965
- 1965-01-18 FR FR2351A patent/FR4316M/fr not_active Expired
- 1965-04-30 ES ES0312472A patent/ES312472A1/es not_active Expired
- 1965-10-22 DK DK541765AA patent/DK120742B/da unknown
- 1965-10-22 DK DK541665AA patent/DK119455B/da unknown
- 1965-10-22 DK DK541865AA patent/DK119105B/da unknown
- 1965-10-22 DK DK541565AA patent/DK120741B/da unknown
- 1965-10-22 DK DK541965AA patent/DK120534B/da unknown
- 1965-10-22 DK DK542065AA patent/DK120588B/da unknown
-
1966
- 1966-11-24 SE SE16075/66A patent/SE334604B/xx unknown
- 1966-11-24 SE SE16078/66A patent/SE334607B/xx unknown
- 1966-11-24 SE SE16077/66A patent/SE334606B/xx unknown
- 1966-11-24 SE SE16074/66A patent/SE334603B/xx unknown
- 1966-11-24 SE SE16079/66A patent/SE334608B/xx unknown
- 1966-11-24 SE SE16076/66A patent/SE334605B/xx unknown
-
1968
- 1968-02-27 SE SE02494/68A patent/SE334621B/xx unknown
- 1968-03-22 CY CY43668A patent/CY436A/xx unknown
- 1968-08-09 US US766008*A patent/US3507961A/en not_active Expired - Lifetime
- 1968-12-31 MY MY1968113A patent/MY6800113A/xx unknown
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