CY436A - Benzenesulphonyl-ureas and process for their manufacture - Google Patents
Benzenesulphonyl-ureas and process for their manufactureInfo
- Publication number
- CY436A CY436A CY43668A CY43668A CY436A CY 436 A CY436 A CY 436A CY 43668 A CY43668 A CY 43668A CY 43668 A CY43668 A CY 43668A CY 436 A CY436 A CY 436A
- Authority
- CY
- Cyprus
- Prior art keywords
- benzenesulphonyl
- ureas
- manufacture
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
- C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
- C07C311/59—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/22—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF41042A DE1185180B (en) | 1963-10-19 | 1963-10-19 | Process for the preparation of benzenesulfonylureas |
| DEF0042062 | 1964-02-20 | ||
| DEF0042933 | 1964-05-21 | ||
| DEF0043268 | 1964-06-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY436A true CY436A (en) | 1968-03-22 |
Family
ID=27436911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY43668A CY436A (en) | 1963-10-19 | 1968-03-22 | Benzenesulphonyl-ureas and process for their manufacture |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US3426067A (en) |
| AT (5) | AT278027B (en) |
| BE (1) | BE654561A (en) |
| CH (1) | CH529115A (en) |
| CY (1) | CY436A (en) |
| DE (1) | DE1185180B (en) |
| DK (7) | DK119052B (en) |
| ES (1) | ES312472A1 (en) |
| FI (1) | FI44597B (en) |
| FR (2) | FR1473834A (en) |
| GB (1) | GB1080705A (en) |
| IL (1) | IL22259A (en) |
| IS (1) | IS765B6 (en) |
| IT (1) | IT1061504B (en) |
| LU (1) | LU47099A1 (en) |
| MC (1) | MC488A1 (en) |
| MY (1) | MY6800113A (en) |
| NL (1) | NL6412137A (en) |
| NO (1) | NO118548B (en) |
| OA (1) | OA01367A (en) |
| SE (8) | SE311151B (en) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1185180B (en) * | 1963-10-19 | 1965-01-14 | Hoechst Ag | Process for the preparation of benzenesulfonylureas |
| DE1493672C3 (en) * | 1964-08-01 | 1974-05-02 | Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt | Process for the preparation of benzenesulfonylureas |
| DE1443905C3 (en) * | 1964-10-30 | 1979-03-15 | Hoechst Ag, 6000 Frankfurt | benzenesulfonyl] -N'-cyclohexylurea, process for its preparation and its use |
| DE1518816C3 (en) * | 1965-03-24 | 1975-05-22 | Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt | Benzenesulfonylureas, processes for their preparation and pharmaceutical preparations containing them |
| US4066639A (en) * | 1965-05-06 | 1978-01-03 | Hoechst Aktiengesellschaft | Benzene-sulfonyl semicarbazides and process for preparing them |
| US3454635A (en) * | 1965-07-27 | 1969-07-08 | Hoechst Ag | Benzenesulfonyl-ureas and process for their manufacture |
| DE1518895C3 (en) * | 1965-12-02 | 1978-12-07 | Hoechst Ag, 6000 Frankfurt | Benzenesulfonylureas, process for their preparation and their use |
| DE1244174C2 (en) * | 1965-09-10 | 1968-01-18 | Hoechst Ag | Process for the preparation of benzenesulfonylureas |
| US3932503A (en) * | 1966-05-28 | 1976-01-13 | Hoechst Aktiengesellschaft | Benzenesulfonyl ureas |
| US3932658A (en) * | 1969-02-25 | 1976-01-13 | Hoechst Aktiengesellschaft | Composition and method for lower blood sugar containing N-[4-(β-<2-methoxy-5-chloro-benzamido>-ethyl)-benzenesulfonyl]-N'-cyclopentyl-urea |
| NL138933B (en) * | 1969-03-26 | 1973-05-15 | Erba Carlo Spa | PROCEDURE FOR PREPARING BENZENE SULPHONYLUREA DERIVATIVES WITH BLOOD SUGAR-MIRROR-LOWERING ACTION. |
| BE754454A (en) * | 1969-08-06 | 1971-02-05 | Bayer Ag | NEW HYPOGLYCEMIC COMPOUNDS OF THE TYPE OF ARYLSULFONYLURIDES AND ARLSULFONYLSEMICARBAZIDES CONTAINING CARBONAMIDE GROUPS |
| ES384463A1 (en) * | 1970-09-23 | 1973-10-01 | Uriach & Cia Sa J | Cyclopentyl urea and process for its production |
| US4072758A (en) * | 1970-09-23 | 1978-02-07 | J. Uriach Y Cia, S.A. | Compositions and methods for effecting glucoreduction |
| US3957866A (en) * | 1970-09-23 | 1976-05-18 | J. Uriach & Cia S.A. | Cyclopentyl carbamide derivative and process for its production |
| BE791638A (en) * | 1971-11-20 | 1973-05-21 | Hoechst Ag | SULFONYL-UREES, THEIR PREPARATION PROCESS AND THEIR APPLICATIONS |
| DE2230543A1 (en) * | 1972-06-22 | 1974-01-17 | Hoechst Ag | BENZENE SULFONYL URUBE AND METHOD FOR MANUFACTURING IT |
| US4067998A (en) * | 1974-02-11 | 1978-01-10 | The Dow Chemical Company | 2-((3,5-Di-tert-butylphenyl)thio) alkanoic acids and derivatives |
| DE2413514C3 (en) * | 1974-03-21 | 1982-03-04 | Hoechst Ag, 6000 Frankfurt | N-Acylaminoathylbenzenesulfonyl-N'-methylureas, process for their preparation and their use |
| AU528362B2 (en) * | 1978-06-22 | 1983-04-28 | Societe D:Etudes De Produits Chimiques | Phenoxy isobutyramides |
| DE3211934A1 (en) * | 1982-03-31 | 1983-10-13 | Hoechst Ag, 6230 Frankfurt | SALICYL ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS AND THEIR USE |
| US4916163A (en) * | 1985-06-04 | 1990-04-10 | The Upjohn Company | Spray-dried lactose formulation of micronized glyburide |
| ES2098069T3 (en) | 1993-02-23 | 1997-04-16 | Hoechst Ag | SUBSTITUTED BENZENE SULFONYL-UREAS AND -TIOUREAS, PROCEDURE FOR THEIR PREPARATION AND USE AS PHARMACEUTICAL AGENTS. |
| HU226462B1 (en) * | 1995-02-17 | 2008-12-29 | Hoechst Ag | Substituted benzol-sulfonyl-ureas and -thioureas, process for producing them, pharmaceutical compositions containing them, and their use |
| CN1195524C (en) * | 1998-09-10 | 2005-04-06 | 阿文蒂斯药物德国有限公司 | Use of benzenesulfonyl (thio) ureas for treatment and prophylaxis of dysfunctions of autonomous nervous system and use of benzenesulfonyl(thio) ureas in combination with beta-receptor blockers |
| DE19923086A1 (en) | 1999-05-20 | 2000-11-23 | Aventis Pharma Gmbh | New cinnamoylaminoalkyl-substituted benzenesulfonamide derivatives, are ATP-sensitive potassium channel inhibitors and vagal nervous system stimulants useful for treating cardiovascular disorders |
| US20010036479A1 (en) | 2000-01-14 | 2001-11-01 | Gillian Cave | Glyburide composition |
| DE10054482A1 (en) | 2000-11-03 | 2002-05-08 | Aventis Pharma Gmbh | Heteroarylacryloylaminoalkyl-substituted benzenesulfonamide derivatives, their production, their use and pharmaceutical preparations containing them |
| DE10054481A1 (en) | 2000-11-03 | 2002-05-08 | Aventis Pharma Gmbh | Acylaminoalkyl-substituted benzenesulfonamide derivatives, their preparation, their use and pharmaceutical compositions containing them |
| WO2003086563A2 (en) * | 2002-04-11 | 2003-10-23 | Carbomer, Inc. | Diabetes imaging probes |
| US20060201981A1 (en) * | 2003-06-30 | 2006-09-14 | Meyer Dean E | Clip support member for golf bag |
| ATE544748T1 (en) * | 2004-12-28 | 2012-02-15 | Kinex Pharmaceuticals Llc | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CELL PROLIFERATION DISEASES |
| US8163956B2 (en) * | 2005-06-13 | 2012-04-24 | Merck Sharp & Dohme Corp. | Inhibitors of GLYT1 transporters |
| US8883852B2 (en) | 2008-10-22 | 2014-11-11 | University of Pittburgh—Of the Commonwealth System of Higher Education | Radioprotective agents |
| WO2012079164A1 (en) * | 2010-12-16 | 2012-06-21 | The Governing Council Of The University Of Toronto | Activators of cylindrical proteases |
| US11840543B2 (en) | 2017-05-24 | 2023-12-12 | The University Of Queensland | Compounds and uses |
| CN112979571B (en) * | 2021-02-24 | 2023-01-31 | 中国药科大学 | AKR1C3 selective inhibitor, preparation method and application thereof |
| WO2022245627A1 (en) * | 2021-05-17 | 2022-11-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | A facile and odor-free approach to convert sulfonyl urea derivatives to chalcogenide sulfonyl urea derivatives |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL218580A (en) * | 1960-04-28 | |||
| DE1185180B (en) * | 1963-10-19 | 1965-01-14 | Hoechst Ag | Process for the preparation of benzenesulfonylureas |
-
1963
- 1963-10-19 DE DEF41042A patent/DE1185180B/en active Pending
-
1964
- 1964-10-07 LU LU47099A patent/LU47099A1/xx unknown
- 1964-10-13 US US403641A patent/US3426067A/en not_active Expired - Lifetime
- 1964-10-14 DK DK506164AA patent/DK119052B/en unknown
- 1964-10-14 IL IL22259A patent/IL22259A/en unknown
- 1964-10-16 IS IS1424A patent/IS765B6/en unknown
- 1964-10-16 AT AT01149/67A patent/AT278027B/en not_active IP Right Cessation
- 1964-10-16 AT AT115067A patent/AT262308B/en active
- 1964-10-16 AT AT881464A patent/AT261627B/en active
- 1964-10-16 AT AT115167A patent/AT262309B/en active
- 1964-10-16 AT AT114867A patent/AT267541B/en active
- 1964-10-16 CH CH1347664A patent/CH529115A/en not_active IP Right Cessation
- 1964-10-16 SE SE12459/64A patent/SE311151B/xx unknown
- 1964-10-17 NO NO155188A patent/NO118548B/no unknown
- 1964-10-19 BE BE654561A patent/BE654561A/xx unknown
- 1964-10-19 FR FR991866A patent/FR1473834A/en not_active Expired
- 1964-10-19 IT IT22418/64A patent/IT1061504B/en active
- 1964-10-19 MC MC515A patent/MC488A1/en unknown
- 1964-10-19 NL NL6412137A patent/NL6412137A/xx unknown
- 1964-10-19 GB GB42547/64A patent/GB1080705A/en not_active Expired
- 1964-10-19 FI FI2196/64A patent/FI44597B/fi active
- 1964-12-31 OA OA51813A patent/OA01367A/en unknown
-
1965
- 1965-01-18 FR FR2351A patent/FR4316M/fr not_active Expired
- 1965-04-30 ES ES0312472A patent/ES312472A1/en not_active Expired
- 1965-10-22 DK DK541565AA patent/DK120741B/en unknown
- 1965-10-22 DK DK541865AA patent/DK119105B/en unknown
- 1965-10-22 DK DK542065AA patent/DK120588B/en unknown
- 1965-10-22 DK DK541965AA patent/DK120534B/en unknown
- 1965-10-22 DK DK541665AA patent/DK119455B/en unknown
- 1965-10-22 DK DK541765AA patent/DK120742B/en unknown
-
1966
- 1966-11-24 SE SE16075/66A patent/SE334604B/xx unknown
- 1966-11-24 SE SE16079/66A patent/SE334608B/xx unknown
- 1966-11-24 SE SE16077/66A patent/SE334606B/xx unknown
- 1966-11-24 SE SE16074/66A patent/SE334603B/xx unknown
- 1966-11-24 SE SE16076/66A patent/SE334605B/xx unknown
- 1966-11-24 SE SE16078/66A patent/SE334607B/xx unknown
-
1968
- 1968-02-27 SE SE02494/68A patent/SE334621B/xx unknown
- 1968-03-22 CY CY43668A patent/CY436A/en unknown
- 1968-08-09 US US766008*A patent/US3507961A/en not_active Expired - Lifetime
- 1968-12-31 MY MY1968113A patent/MY6800113A/en unknown
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