DK1169060T3 - Natriumkanalblokkerpræparater og anvendelse deraf - Google Patents
Natriumkanalblokkerpræparater og anvendelse derafInfo
- Publication number
- DK1169060T3 DK1169060T3 DK00923183T DK00923183T DK1169060T3 DK 1169060 T3 DK1169060 T3 DK 1169060T3 DK 00923183 T DK00923183 T DK 00923183T DK 00923183 T DK00923183 T DK 00923183T DK 1169060 T3 DK1169060 T3 DK 1169060T3
- Authority
- DK
- Denmark
- Prior art keywords
- sodium channel
- channel blocker
- preparations
- blocker preparations
- convulsion
- Prior art date
Links
- 229940125794 sodium channel blocker Drugs 0.000 title abstract 2
- 239000003195 sodium channel blocking agent Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title 1
- 208000000094 Chronic Pain Diseases 0.000 abstract 2
- 206010010904 Convulsion Diseases 0.000 abstract 2
- UGJMXCAKCUNAIE-UHFFFAOYSA-N Gabapentin Chemical compound OC(=O)CC1(CN)CCCCC1 UGJMXCAKCUNAIE-UHFFFAOYSA-N 0.000 abstract 2
- 208000002193 Pain Diseases 0.000 abstract 2
- 230000036461 convulsion Effects 0.000 abstract 2
- 229960002870 gabapentin Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229960001233 pregabalin Drugs 0.000 abstract 1
- AYXYPKUFHZROOJ-ZETCQYMHSA-N pregabalin Chemical compound CC(C)C[C@H](CN)CC(O)=O AYXYPKUFHZROOJ-ZETCQYMHSA-N 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12854399P | 1999-04-09 | 1999-04-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1169060T3 true DK1169060T3 (da) | 2006-01-16 |
Family
ID=22435837
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00923183T DK1169060T3 (da) | 1999-04-09 | 2000-04-10 | Natriumkanalblokkerpræparater og anvendelse deraf |
Country Status (9)
Country | Link |
---|---|
US (3) | US20020037926A1 (ja) |
EP (1) | EP1169060B1 (ja) |
JP (1) | JP2002541215A (ja) |
AT (1) | ATE303162T1 (ja) |
AU (1) | AU4334900A (ja) |
CA (1) | CA2370030C (ja) |
DE (1) | DE60022333T2 (ja) |
DK (1) | DK1169060T3 (ja) |
WO (1) | WO2000061188A1 (ja) |
Families Citing this family (60)
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JP2002541215A (ja) * | 1999-04-09 | 2002-12-03 | ユーロ−セルティック エス. ア. | ナトリウムチャネル遮断薬組成物およびその使用 |
US7164034B2 (en) * | 1999-06-10 | 2007-01-16 | Pfizer Inc. | Alpha2delta ligands for fibromyalgia and other disorders |
US20080207755A1 (en) * | 2000-05-31 | 2008-08-28 | Pfizer Inc | Alpha 2 Delta Ligands For Fibromyalgia and Other Disorders |
NZ531586A (en) * | 2001-09-03 | 2005-09-30 | Newron Pharm Spa | Pharmaceutical composition comprising gabapentin or an analogue thereof and an alpha-aminoamide and its analgesic use |
US20030124174A1 (en) * | 2001-10-25 | 2003-07-03 | Endo Pharmaceuticals, Inc | Method for treating non-neuropathic pain |
BRPI0200751B1 (pt) * | 2002-02-06 | 2018-10-23 | Univ Minas Gerais | complexos de inclusão de benzaldeído semicabazona em ciclodextrinas e seu método de preparação |
CA2474751A1 (en) | 2002-02-25 | 2003-09-04 | Vanderbilt University | Expression system for human brain-specific voltage-gated sodium channel, type 1 |
JP2006513257A (ja) * | 2002-12-13 | 2006-04-20 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | 線維筋痛症および他の障害を処置するためのプレガバリン誘導体 |
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DE10332487A1 (de) * | 2003-07-16 | 2005-02-10 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ambroxol für die Behandlung von chronisch nozizeptiven Schmerzen |
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US9045435B2 (en) | 2010-10-05 | 2015-06-02 | Purdue Pharma, L.P. | Quinazoline compounds as sodium channel blockers |
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US10004710B2 (en) * | 2013-01-18 | 2018-06-26 | Kemphys Ltd. | Medicament for therapeutic treatment of neuropathic disease |
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EP3083606B1 (en) | 2013-12-20 | 2020-10-28 | Purdue Pharma LP | Pyrimidines and use thereof |
US9695144B2 (en) | 2013-12-23 | 2017-07-04 | Purdue Pharma L.P. | Dibenzazepine derivatives and use thereof |
EP3087059B1 (en) | 2013-12-23 | 2020-04-29 | Purdue Pharma L.P. | Indazoles and use thereof |
EP3089978B1 (en) | 2013-12-30 | 2018-08-29 | Purdue Pharma L.P. | Pyridone-sulfone morphinan analogs as opioid receptor ligands |
US10047075B2 (en) | 2014-01-24 | 2018-08-14 | Purdue Pharma L.P. | Pyridines and pyrimidines and use thereof |
AU2015217185B2 (en) | 2014-02-12 | 2018-04-05 | Purdue Pharma L.P. | Isoquinoline derivatives and use thereof |
US10730866B2 (en) | 2014-04-07 | 2020-08-04 | Purdue Pharma L.P. | Indole derivatives and use thereof |
CA2948144A1 (en) | 2014-05-06 | 2015-11-12 | Purdue Pharma L.P. | Benzomorphan analogs and use thereof |
CA2952124A1 (en) | 2014-06-13 | 2015-12-17 | Purdue Pharma L.P. | Heterocyclic morphinan derivatives and use thereof |
EP3154972A4 (en) | 2014-06-13 | 2017-11-22 | Purdue Pharma L.P. | Azamophinan derivatives and use thereof |
WO2018125716A1 (en) | 2017-01-02 | 2018-07-05 | Purdue Pharma L.P. | Morphinan derivatives and use thereof |
JP2024509372A (ja) * | 2021-02-26 | 2024-03-01 | ヴァイルマ インコーポレイテッド | ガバペンチノイドの局所投与のための方法及び製剤 |
CN115554293A (zh) * | 2021-07-01 | 2023-01-03 | 南京宁丹新药技术有限公司 | 一种药物组合物及其用途 |
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ES2137137B1 (es) | 1998-05-25 | 2000-08-16 | Medichem Sa | Nuevo polimorfo de gabapentina no hidratada, su procedimiento de obtencion y su utilizacion para la obtencion de gabapentina de calidad farmaceutica. |
SI1093366T1 (en) | 1998-07-09 | 2005-02-28 | Warner-Lambert Company Llc | Pharmaceutical composition containing gaba analogs and an antiviral agent to treat shingles |
PL345340A1 (en) | 1998-07-09 | 2001-12-17 | Warner Lambert Co | Compositions comprising gaba analogs and caffeine |
US6281211B1 (en) | 1999-02-04 | 2001-08-28 | Euro-Celtique S.A. | Substituted semicarbazides and the use thereof |
TR200102790T2 (tr) | 1999-03-26 | 2002-06-21 | Euro-Celtique S.A. | Aril İkameli Pirazoller, İmidazoller, Oksazoller, Tiazoller ve Piroller Ve Bunların Kullanımı. |
JP2002541215A (ja) * | 1999-04-09 | 2002-12-03 | ユーロ−セルティック エス. ア. | ナトリウムチャネル遮断薬組成物およびその使用 |
EP1200086A4 (en) | 1999-08-04 | 2009-05-27 | Icagen Inc | THERAPEUTIC OR PROPHYLACTIC METHODS OF PAIN AND ANXIETY |
US6113915A (en) | 1999-10-12 | 2000-09-05 | Allergan Sales, Inc. | Methods for treating pain |
NZ531586A (en) | 2001-09-03 | 2005-09-30 | Newron Pharm Spa | Pharmaceutical composition comprising gabapentin or an analogue thereof and an alpha-aminoamide and its analgesic use |
-
2000
- 2000-04-10 JP JP2000610520A patent/JP2002541215A/ja active Pending
- 2000-04-10 DK DK00923183T patent/DK1169060T3/da active
- 2000-04-10 DE DE60022333T patent/DE60022333T2/de not_active Expired - Lifetime
- 2000-04-10 EP EP00923183A patent/EP1169060B1/en not_active Expired - Lifetime
- 2000-04-10 WO PCT/US2000/009387 patent/WO2000061188A1/en active IP Right Grant
- 2000-04-10 AU AU43349/00A patent/AU4334900A/en not_active Abandoned
- 2000-04-10 CA CA002370030A patent/CA2370030C/en not_active Expired - Fee Related
- 2000-04-10 AT AT00923183T patent/ATE303162T1/de active
-
2001
- 2001-10-05 US US09/971,007 patent/US20020037926A1/en not_active Abandoned
-
2003
- 2003-08-21 US US10/644,783 patent/US7393872B2/en not_active Expired - Lifetime
-
2008
- 2008-06-13 US US12/138,568 patent/US20080318932A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE303162T1 (de) | 2005-09-15 |
CA2370030C (en) | 2007-08-14 |
US20040054005A1 (en) | 2004-03-18 |
DE60022333D1 (de) | 2005-10-06 |
US20020037926A1 (en) | 2002-03-28 |
CA2370030A1 (en) | 2000-10-19 |
WO2000061188A1 (en) | 2000-10-19 |
EP1169060A1 (en) | 2002-01-09 |
EP1169060B1 (en) | 2005-08-31 |
US20080318932A1 (en) | 2008-12-25 |
WO2000061188A9 (en) | 2002-02-14 |
JP2002541215A (ja) | 2002-12-03 |
AU4334900A (en) | 2000-11-14 |
US7393872B2 (en) | 2008-07-01 |
DE60022333T2 (de) | 2006-07-06 |
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