DK115631B - Fremgangsmåde til fremstilling af analgetisk og narkotisk antagonistisk virksomme derivater af 14-hydroxydihydronormorfin eller farmaceutisk acceptable salte deraf. - Google Patents

Fremgangsmåde til fremstilling af analgetisk og narkotisk antagonistisk virksomme derivater af 14-hydroxydihydronormorfin eller farmaceutisk acceptable salte deraf.

Info

Publication number
DK115631B
DK115631B DK667766AA DK667766A DK115631B DK 115631 B DK115631 B DK 115631B DK 667766A A DK667766A A DK 667766AA DK 667766 A DK667766 A DK 667766A DK 115631 B DK115631 B DK 115631B
Authority
DK
Denmark
Prior art keywords
narcotically
hydroxydihydronormorphine
analgesically
preparation
pharmaceutically acceptable
Prior art date
Application number
DK667766AA
Other languages
Danish (da)
English (en)
Inventor
H Blumberg
I Pachter
Z Matossian
Original Assignee
Endo Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endo Lab filed Critical Endo Lab
Publication of DK115631B publication Critical patent/DK115631B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK667766AA 1966-01-19 1966-12-23 Fremgangsmåde til fremstilling af analgetisk og narkotisk antagonistisk virksomme derivater af 14-hydroxydihydronormorfin eller farmaceutisk acceptable salte deraf. DK115631B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52170866A 1966-01-19 1966-01-19
US677727A US3393197A (en) 1966-01-19 1967-10-24 Nu-substituted-14-hydroxydihydronormorphines

Publications (1)

Publication Number Publication Date
DK115631B true DK115631B (da) 1969-10-27

Family

ID=27060549

Family Applications (1)

Application Number Title Priority Date Filing Date
DK667766AA DK115631B (da) 1966-01-19 1966-12-23 Fremgangsmåde til fremstilling af analgetisk og narkotisk antagonistisk virksomme derivater af 14-hydroxydihydronormorfin eller farmaceutisk acceptable salte deraf.

Country Status (13)

Country Link
US (1) US3393197A (enExample)
AT (1) AT292206B (enExample)
CH (1) CH493522A (enExample)
DE (2) DE1795707C3 (enExample)
DK (1) DK115631B (enExample)
ES (1) ES334942A1 (enExample)
FR (1) FR6112M (enExample)
GB (1) GB1119270A (enExample)
IL (1) IL26896A (enExample)
LU (1) LU52650A1 (enExample)
NL (2) NL165744C (enExample)
NO (1) NO120368B (enExample)
SE (1) SE329402B (enExample)

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US4237140A (en) * 1979-05-18 1980-12-02 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and acetaminophen
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US4366159A (en) * 1981-09-08 1982-12-28 Michael Richard Magruder Nalbuphine-narcotic analgesic composition and method of producing analgesia
US4404211A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and flurbiprofen
US4404210A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and ibuprofen
US4404208A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and tiflamizole
US4407804A (en) * 1982-06-30 1983-10-04 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and indomethacin
US4407805A (en) * 1982-06-30 1983-10-04 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and zomepirac
US4404209A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and sulindac
AU565634B2 (en) * 1982-06-30 1987-09-24 E.I. Du Pont De Nemours And Company Synergistic compositions of nalbuphine and non-narcotic analgesic compounds
US4402962A (en) * 1982-06-30 1983-09-06 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and 4,5-bis(4-methoxyphenyl)-2-(trifluoromethylsulfonyl)-1H-imidazole
US4477457A (en) * 1982-10-28 1984-10-16 E. I. Du Pont De Nemours And Company Method for inducing anorexia using nalmetrene
US4478840A (en) * 1983-10-11 1984-10-23 E. I. Du Pont De Nemours And Company Appetite suppressing compositions and methods
US4668685A (en) * 1984-07-05 1987-05-26 E.I. Du Pont De Nemours And Company Substituted benzoate ester prodrug derivatives of 3-hydroxymorphinans, which are analgesics or narcotic antagonists
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US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
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US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
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US3320262A (en) * 1964-09-22 1967-05-16 Lewenstein 14 hydroxy morphine and codeine carboxymethyloximes

Also Published As

Publication number Publication date
DE1670616A1 (de) 1970-09-10
DE1670616B2 (de) 1977-11-10
FR6112M (enExample) 1968-06-17
GB1119270A (en) 1968-07-10
NL7805652A (nl) 1978-09-29
AT292206B (de) 1971-08-25
NL165744B (nl) 1980-12-15
DE1670616C3 (de) 1978-06-29
DE1795707B2 (de) 1979-04-19
LU52650A1 (enExample) 1967-02-20
CH493522A (de) 1970-07-15
NL6618022A (enExample) 1967-07-20
ES334942A1 (es) 1968-03-01
DE1795707A1 (de) 1973-10-11
US3393197A (en) 1968-07-16
IL26896A (en) 1970-11-30
NL165744C (nl) 1981-05-15
NO120368B (enExample) 1970-10-12
SE329402B (enExample) 1970-10-12
DE1795707C3 (de) 1979-12-20

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