DK1144425T3 - Derivater af monosaccharider som celleadhæsionsinhibitorer - Google Patents
Derivater af monosaccharider som celleadhæsionsinhibitorerInfo
- Publication number
- DK1144425T3 DK1144425T3 DK00900087T DK00900087T DK1144425T3 DK 1144425 T3 DK1144425 T3 DK 1144425T3 DK 00900087 T DK00900087 T DK 00900087T DK 00900087 T DK00900087 T DK 00900087T DK 1144425 T3 DK1144425 T3 DK 1144425T3
- Authority
- DK
- Denmark
- Prior art keywords
- monosaccharides
- derivatives
- cell adhesion
- adhesion inhibitors
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
- C07H9/04—Cyclic acetals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22915599A | 1999-01-12 | 1999-01-12 | |
US09/411,357 US6329344B1 (en) | 1998-10-22 | 1999-10-01 | Derivatives of monosaccharides as cell adhesion inhibitors |
EP00900087A EP1144425B1 (fr) | 1999-01-12 | 2000-01-10 | Derives de monosaccharides en tant qu'inhibiteurs de l'adhesion cellulaire |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1144425T3 true DK1144425T3 (da) | 2004-10-18 |
Family
ID=26922990
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00900087T DK1144425T3 (da) | 1999-01-12 | 2000-01-10 | Derivater af monosaccharider som celleadhæsionsinhibitorer |
Country Status (29)
Country | Link |
---|---|
US (1) | US6329344B1 (fr) |
EP (1) | EP1144425B1 (fr) |
JP (1) | JP2002534529A (fr) |
CN (1) | CN1254478C (fr) |
AR (1) | AR033939A1 (fr) |
AT (1) | ATE269349T1 (fr) |
AU (1) | AU767948B2 (fr) |
BG (1) | BG105795A (fr) |
BR (1) | BR0007489A (fr) |
CA (1) | CA2359980A1 (fr) |
CO (1) | CO5170511A1 (fr) |
CZ (1) | CZ20012541A3 (fr) |
DE (1) | DE60011568T2 (fr) |
DK (1) | DK1144425T3 (fr) |
ES (1) | ES2223447T3 (fr) |
HK (1) | HK1041006B (fr) |
HR (1) | HRP20010527B1 (fr) |
HU (1) | HUP0200097A3 (fr) |
ID (1) | ID30259A (fr) |
IL (2) | IL144274A0 (fr) |
MA (1) | MA25679A1 (fr) |
MY (1) | MY122723A (fr) |
NZ (2) | NZ512851A (fr) |
PA (1) | PA8489601A1 (fr) |
PT (1) | PT1144425E (fr) |
SK (1) | SK284568B6 (fr) |
TR (1) | TR200102031T2 (fr) |
WO (1) | WO2000042053A1 (fr) |
YU (1) | YU50101A (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL152397A (en) * | 2002-10-21 | 2009-02-11 | Hadasit Med Res Service | Compositions and compounds for the treatment of hyperglycemia |
WO2004071515A1 (fr) * | 2003-02-12 | 2004-08-26 | Ranbaxy Laboratories Limited | Preparation de derives de monosaccharide |
WO2004099229A1 (fr) * | 2003-05-06 | 2004-11-18 | Ranbaxy Laboratories Limited | Procede de synthese des sels d'addition de base de 5,6-dideoxy-5-n-(4-(2-hydroxy-2-oxoethyl)-phenylaminocarbonyl) amino-l-gulofuranosides substitues par 2,3-0-isopropylidene-1-0 |
EA009646B1 (ru) | 2003-05-30 | 2008-02-28 | Рэнбакси Лабораториз Лтд. | Замещённые производные пиррола и их применение в качестве ингибиторов hmg-coa |
WO2005030735A1 (fr) * | 2003-09-25 | 2005-04-07 | Ranbaxy Laboratories Limited | Derives de triazines comme inhibiteurs de l'adhesion cellulaire |
WO2005092908A1 (fr) * | 2004-03-18 | 2005-10-06 | Ranbaxy Laboratories Limited | Sels d'addition basiques de derives monosaccharides utilises en tant qu'inhibiteurs de l'hyperreactivite des voies aeriennes et des inflammations des voies aeriennes |
WO2005092907A2 (fr) * | 2004-03-26 | 2005-10-06 | Ranbaxy Laboratories Limited | Derives de monosaccharide |
WO2005100373A2 (fr) * | 2004-04-13 | 2005-10-27 | Ranbaxy Laboratories Limited | Derives du monosaccharide |
WO2006024926A1 (fr) * | 2004-09-02 | 2006-03-09 | Ranbaxy Laboratories Limited | Derives de monosaccharide |
JP2008525421A (ja) * | 2004-12-22 | 2008-07-17 | ランバクシー ラボラトリーズ リミテッド | モノサッカリド誘導体 |
WO2007010499A2 (fr) * | 2005-07-22 | 2007-01-25 | Ranbaxy Laboratories Limited | Derives de monosaccharides utilises comme inhibiteurs de 5-lipoxygenase |
AU2006313430B2 (en) | 2005-11-08 | 2012-09-06 | Ranbaxy Laboratories Limited | Process for (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt |
EP1842855A3 (fr) * | 2006-03-29 | 2007-12-05 | Ranbaxy Laboratories Limited | Dérivés de monosaccharide en tant qu'agnets antiinflammaotoires et/ou agents anticancéreux |
EP1864992A2 (fr) * | 2006-05-30 | 2007-12-12 | Ranbaxy Laboratories, Ltd. | Dérivés de monosaccharide |
EP1953170A1 (fr) * | 2006-10-03 | 2008-08-06 | Ranbaxy Laboratories Limited | Dérivés de monosaccharide en tant qu'agents anti-inflammatoires |
CN105367612A (zh) * | 2014-08-13 | 2016-03-02 | 中国药科大学 | 龙脷叶由来天然产物丁基2-脱氧-3,6-脱水-β-D-阿拉伯糖呋喃糖苷的全合成方法 |
US20220356150A1 (en) * | 2021-04-30 | 2022-11-10 | Evoco Limited | Biobased diisocyanates, and process for preparation of same |
WO2024135721A1 (fr) * | 2022-12-21 | 2024-06-27 | 田辺三菱製薬株式会社 | Procédé de production d'un intermédiaire de production, intermédiaire de production obtenu à partir de celui-ci et procédé de production d'un intermédiaire d'acide nucléique artificiel réticulé faisant appel à celui-ci |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2715121A (en) | 1950-09-09 | 1955-08-09 | American Home Prod | Alkyl sugar derivatives and their preparation |
US4056322A (en) | 1973-12-14 | 1977-11-01 | Strategic Medical Research Corporation | Preparation of ethers of monosaccharides |
DE2936240A1 (de) * | 1979-09-07 | 1981-03-26 | Bayer Ag, 51373 Leverkusen | Verfahren zur herstellung bekannter und neuer 6-amino-6-desoxy-2,3-0-isopropyliden-(alpha)-l-sorbofuranose-derivate sowie neue zwischenprodukte des verfahrens |
US4735934A (en) | 1981-02-17 | 1988-04-05 | Greenwich Pharmaceuticals Incorporated | Method of therapeutically treating a warm blooded animal afflicted with an autoimmune disease |
US4996195A (en) | 1989-01-09 | 1991-02-26 | Greenwich Pharmaceuticals Inc. | Derivatives of α,D-glucofuranose or α,D-allofuranose and intermediates for preparing these derivatives |
US5298494A (en) | 1989-01-09 | 1994-03-29 | Greenwich Pharmaceuticals Incorporated | Monosaccharides having anti-proliferation and anti-inflammatory activity, compositions and uses thereof |
US5010058A (en) | 1989-06-22 | 1991-04-23 | 501 Greenwich Pharmaceuticals Incorporated | 3,5,6-substituted derivatives of 1,2-O-isopropylidene-α,D-glucofuranose and intermediates for preparing these derivatives |
US5192746A (en) | 1990-07-09 | 1993-03-09 | Tanabe Seiyaku Co., Ltd. | Cyclic cell adhesion modulation compounds |
IL100833A0 (en) | 1991-02-20 | 1992-09-06 | Greenwich Pharma | Method for synthesis of ethereally substituted blocked monosaccharides |
US5360792A (en) | 1991-12-20 | 1994-11-01 | Greenwich Pharmaceuticals Incorporated | Anti-proliferative and anti-inflammatory compounds: 5- or 6-deoxy hexose monosaccharides having a saturated nitrogen-containing heterocycle at the 5- or 6-position bound through the nitrogen atom |
US5360794A (en) | 1992-08-03 | 1994-11-01 | Medicarb Inc. | Disubstituted and deoxy disubstituted derivatives of α-D-mannofuranosides and β-L-gulofuranosides having anti-inflammatory and anti-proliferative activity |
US5367062A (en) | 1992-08-21 | 1994-11-22 | Medicarb Inc. | Disubstituted and deoxydisubstituted derivatives of α-d-lyxofuranosides having anti-inflammatory and anti-proliferative activity |
US5508387A (en) * | 1993-08-04 | 1996-04-16 | Glycomed Incorporated | Selectin binding glycopeptides |
WO1995010296A1 (fr) * | 1993-10-12 | 1995-04-20 | Glycomed Incorporated | Banque de glyco-peptides permettant d'identifier des inhibiteurs d'adherence intercellulaire |
US5637570A (en) | 1995-05-09 | 1997-06-10 | Chemora Pharmochem | Disubstituted and trisubstituted derivatives of 2,3:4,6-di-O-isopropylidene-α-L-xylo-2-hexulofuranosonic acid having anti-cancer, anti-inflammatory and anti-proliferative activity |
EP0859005A1 (fr) * | 1995-10-26 | 1998-08-19 | Kanebo, Ltd. | Derives de la fucose, medicaments dont ils forment le principe actif, et leurs intermediaires de fabrication |
US5824657A (en) | 1997-03-18 | 1998-10-20 | Cubist Pharmaceuticals, Inc. | Aminoacyl sulfamides for the treatment of hyperproliferative disorders |
-
1999
- 1999-10-01 US US09/411,357 patent/US6329344B1/en not_active Expired - Fee Related
-
2000
- 2000-01-10 EP EP00900087A patent/EP1144425B1/fr not_active Expired - Lifetime
- 2000-01-10 IL IL14427400A patent/IL144274A0/xx not_active IP Right Cessation
- 2000-01-10 CA CA002359980A patent/CA2359980A1/fr not_active Abandoned
- 2000-01-10 BR BR0007489-6A patent/BR0007489A/pt not_active IP Right Cessation
- 2000-01-10 WO PCT/IB2000/000021 patent/WO2000042053A1/fr active IP Right Grant
- 2000-01-10 NZ NZ512851A patent/NZ512851A/xx unknown
- 2000-01-10 SK SK996-2001A patent/SK284568B6/sk unknown
- 2000-01-10 TR TR2001/02031T patent/TR200102031T2/xx unknown
- 2000-01-10 NZ NZ527482A patent/NZ527482A/en unknown
- 2000-01-10 CZ CZ20012541A patent/CZ20012541A3/cs unknown
- 2000-01-10 PT PT00900087T patent/PT1144425E/pt unknown
- 2000-01-10 DE DE60011568T patent/DE60011568T2/de not_active Expired - Fee Related
- 2000-01-10 YU YU50101A patent/YU50101A/sh unknown
- 2000-01-10 HU HU0200097A patent/HUP0200097A3/hu unknown
- 2000-01-10 DK DK00900087T patent/DK1144425T3/da active
- 2000-01-10 AR ARP000100085A patent/AR033939A1/es not_active Application Discontinuation
- 2000-01-10 AU AU18860/00A patent/AU767948B2/en not_active Ceased
- 2000-01-10 ID IDW00200101521A patent/ID30259A/id unknown
- 2000-01-10 CN CNB008048428A patent/CN1254478C/zh not_active Expired - Fee Related
- 2000-01-10 JP JP2000593620A patent/JP2002534529A/ja active Pending
- 2000-01-10 AT AT00900087T patent/ATE269349T1/de not_active IP Right Cessation
- 2000-01-10 ES ES00900087T patent/ES2223447T3/es not_active Expired - Lifetime
- 2000-01-11 MY MYPI20000074A patent/MY122723A/en unknown
- 2000-01-12 CO CO00001165A patent/CO5170511A1/es not_active Application Discontinuation
- 2000-01-12 PA PA20008489601A patent/PA8489601A1/es unknown
-
2001
- 2001-07-11 IL IL144274A patent/IL144274A/en unknown
- 2001-07-12 HR HR20010527A patent/HRP20010527B1/xx not_active IP Right Cessation
- 2001-07-12 MA MA26265A patent/MA25679A1/fr unknown
- 2001-08-08 BG BG105795A patent/BG105795A/xx unknown
-
2002
- 2002-04-16 HK HK02102882.5A patent/HK1041006B/zh not_active IP Right Cessation
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