NO20015033L - Anvendelse av maduraftalazinderivater som inhibitorer av proinflammatoriske cytokiner - Google Patents

Anvendelse av maduraftalazinderivater som inhibitorer av proinflammatoriske cytokiner

Info

Publication number
NO20015033L
NO20015033L NO20015033A NO20015033A NO20015033L NO 20015033 L NO20015033 L NO 20015033L NO 20015033 A NO20015033 A NO 20015033A NO 20015033 A NO20015033 A NO 20015033A NO 20015033 L NO20015033 L NO 20015033L
Authority
NO
Norway
Prior art keywords
pro
inhibitors
inflammatory cytokines
maduraphthalazine
derivatives
Prior art date
Application number
NO20015033A
Other languages
English (en)
Other versions
NO20015033D0 (no
Inventor
Regina Draheim
Thomas Kronbach
Lothar Heinisch
Ernst Roemer
Norbert Hoefgen
Hildegard Poppe
Peter Jutten
Wolfgang Haas
Walter Werner
Udo Graefe
Original Assignee
Dresden Arzneimittel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dresden Arzneimittel filed Critical Dresden Arzneimittel
Publication of NO20015033D0 publication Critical patent/NO20015033D0/no
Publication of NO20015033L publication Critical patent/NO20015033L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20015033A 1999-04-17 2001-10-16 Anvendelse av maduraftalazinderivater som inhibitorer av proinflammatoriske cytokiner NO20015033L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19917505A DE19917505A1 (de) 1999-04-17 1999-04-17 Verwendung von Maduraphthalazin-Derivaten als Inhibitoren proinflammatorischer Cytokine
PCT/EP2000/003182 WO2000063181A1 (de) 1999-04-17 2000-04-11 Verwendung von maduraphthalazin-derivaten als inhibitoren proinflammatorischer cytokine

Publications (2)

Publication Number Publication Date
NO20015033D0 NO20015033D0 (no) 2001-10-16
NO20015033L true NO20015033L (no) 2001-11-21

Family

ID=7904992

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20015033A NO20015033L (no) 1999-04-17 2001-10-16 Anvendelse av maduraftalazinderivater som inhibitorer av proinflammatoriske cytokiner

Country Status (24)

Country Link
US (1) US6440968B1 (no)
EP (1) EP1171425A1 (no)
JP (1) JP2002542232A (no)
KR (1) KR20010108515A (no)
CN (1) CN1347408A (no)
AU (1) AU4546100A (no)
BG (1) BG106009A (no)
BR (1) BR0009821A (no)
CA (1) CA2305893A1 (no)
CZ (1) CZ20013712A3 (no)
DE (1) DE19917505A1 (no)
EA (1) EA200101096A1 (no)
EE (1) EE200100537A (no)
HK (1) HK1039932A1 (no)
HU (1) HUP0200783A3 (no)
IL (1) IL145600A0 (no)
IS (1) IS6093A (no)
MX (1) MXPA01010050A (no)
NO (1) NO20015033L (no)
SK (1) SK14812001A3 (no)
TR (1) TR200102984T2 (no)
WO (1) WO2000063181A1 (no)
YU (1) YU72601A (no)
ZA (1) ZA200107886B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0210535D0 (en) * 2002-05-08 2002-06-19 Novartis Ag Organic compounds
CA2492542A1 (en) * 2002-07-30 2004-02-05 Stem Cell Therapeutics Inc. Oligodendrocyte production from multipotent neural stem cells
WO2004056868A2 (en) * 2002-12-19 2004-07-08 Endocube Sas Nf-hev compositions and methods of use
US20080096947A1 (en) * 2004-10-15 2008-04-24 Heidelberg Pharma Ag Parenteral Forms Of Administration Of Imexon And Method For The Production Thereof
EP1908754B1 (en) * 2006-09-19 2009-01-28 Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e.V. Hans-Knöll-Institut Antibiotic maduraphthalazin salts with delayed release of the active substance and their use
JP7370705B2 (ja) 2016-07-11 2023-10-30 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 疎水性カプセル
EP3898610B1 (en) * 2018-12-21 2022-10-19 Fondazione Istituto Insubrico di Ricerca per la Vita Novel aza-hexaphene antibiotic compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE7706C (de) * Dr. G. H. E. BERING in Bromberg Verfahren zur Entbitterung von Lupinen mit Hülfe kohlensaurer Alkalien
DE19719522A1 (de) * 1996-08-17 1998-02-19 Gruenenthal Gmbh Neue polycyclische Phthalazinderivate, Verfahren zu Ihrer Herstellung und ihre Verwendung

Also Published As

Publication number Publication date
NO20015033D0 (no) 2001-10-16
WO2000063181A1 (de) 2000-10-26
DE19917505A1 (de) 2000-10-19
CN1347408A (zh) 2002-05-01
YU72601A (sh) 2004-05-12
JP2002542232A (ja) 2002-12-10
IL145600A0 (en) 2002-06-30
HUP0200783A2 (hu) 2002-11-28
CA2305893A1 (en) 2000-10-17
HK1039932A1 (zh) 2002-05-17
US6440968B1 (en) 2002-08-27
BR0009821A (pt) 2002-01-15
BG106009A (en) 2002-06-28
SK14812001A3 (sk) 2002-05-09
EP1171425A1 (de) 2002-01-16
HUP0200783A3 (en) 2002-12-28
EA200101096A1 (ru) 2002-04-25
TR200102984T2 (tr) 2002-03-21
IS6093A (is) 2001-09-28
KR20010108515A (ko) 2001-12-07
ZA200107886B (en) 2004-03-29
EE200100537A (et) 2002-12-16
CZ20013712A3 (cs) 2002-03-13
AU4546100A (en) 2000-11-02
MXPA01010050A (es) 2002-04-24

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