BG105795A - Derivatives of monosaccharides as cell adhesion inhibitors - Google Patents

Derivatives of monosaccharides as cell adhesion inhibitors

Info

Publication number
BG105795A
BG105795A BG105795A BG10579501A BG105795A BG 105795 A BG105795 A BG 105795A BG 105795 A BG105795 A BG 105795A BG 10579501 A BG10579501 A BG 10579501A BG 105795 A BG105795 A BG 105795A
Authority
BG
Bulgaria
Prior art keywords
cell adhesion
derivatives
monosaccharides
adhesion inhibitors
methods
Prior art date
Application number
BG105795A
Other languages
Bulgarian (bg)
English (en)
Inventor
Sudershan Arora
Madan TANWAR
Jang Gupta
Geeta Sharma
Original Assignee
Ranbaxy Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Limited filed Critical Ranbaxy Laboratories Limited
Publication of BG105795A publication Critical patent/BG105795A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BG105795A 1999-01-12 2001-08-08 Derivatives of monosaccharides as cell adhesion inhibitors BG105795A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22915599A 1999-01-12 1999-01-12
US09/411,357 US6329344B1 (en) 1998-10-22 1999-10-01 Derivatives of monosaccharides as cell adhesion inhibitors
PCT/IB2000/000021 WO2000042053A1 (fr) 1999-01-12 2000-01-10 Derives de monosaccharides en tant qu'inhibiteurs de l'adhesion cellulaire

Publications (1)

Publication Number Publication Date
BG105795A true BG105795A (en) 2002-05-31

Family

ID=26922990

Family Applications (1)

Application Number Title Priority Date Filing Date
BG105795A BG105795A (en) 1999-01-12 2001-08-08 Derivatives of monosaccharides as cell adhesion inhibitors

Country Status (29)

Country Link
US (1) US6329344B1 (fr)
EP (1) EP1144425B1 (fr)
JP (1) JP2002534529A (fr)
CN (1) CN1254478C (fr)
AR (1) AR033939A1 (fr)
AT (1) ATE269349T1 (fr)
AU (1) AU767948B2 (fr)
BG (1) BG105795A (fr)
BR (1) BR0007489A (fr)
CA (1) CA2359980A1 (fr)
CO (1) CO5170511A1 (fr)
CZ (1) CZ20012541A3 (fr)
DE (1) DE60011568T2 (fr)
DK (1) DK1144425T3 (fr)
ES (1) ES2223447T3 (fr)
HK (1) HK1041006B (fr)
HR (1) HRP20010527B1 (fr)
HU (1) HUP0200097A3 (fr)
ID (1) ID30259A (fr)
IL (2) IL144274A0 (fr)
MA (1) MA25679A1 (fr)
MY (1) MY122723A (fr)
NZ (2) NZ512851A (fr)
PA (1) PA8489601A1 (fr)
PT (1) PT1144425E (fr)
SK (1) SK284568B6 (fr)
TR (1) TR200102031T2 (fr)
WO (1) WO2000042053A1 (fr)
YU (1) YU50101A (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL152397A (en) * 2002-10-21 2009-02-11 Hadasit Med Res Service Compositions and compounds for the treatment of hyperglycemia
WO2004071515A1 (fr) * 2003-02-12 2004-08-26 Ranbaxy Laboratories Limited Preparation de derives de monosaccharide
AU2003222399A1 (en) * 2003-05-06 2004-11-26 Ranbaxy Laboratories Limited Process for the synthesis of base addition salts of 2,3-0-isopropylidene-1-0-substituted-5,6-dideoxy-5-n- (4-(2-hydroxy-2-oxoethyl)-phenylaminocarbonyl) amino-l-gulofuranosides
CA2753318A1 (fr) 2003-05-30 2004-12-09 Ranbaxy Laboratories Limited Derives pyrroliques substitues
US20060004005A1 (en) * 2003-09-25 2006-01-05 Sattigeri Viswajanani J Triazines derivatives as cell adhesion inhibitors
WO2005092908A1 (fr) * 2004-03-18 2005-10-06 Ranbaxy Laboratories Limited Sels d'addition basiques de derives monosaccharides utilises en tant qu'inhibiteurs de l'hyperreactivite des voies aeriennes et des inflammations des voies aeriennes
WO2005092907A2 (fr) * 2004-03-26 2005-10-06 Ranbaxy Laboratories Limited Derives de monosaccharide
WO2005100373A2 (fr) * 2004-04-13 2005-10-27 Ranbaxy Laboratories Limited Derives du monosaccharide
US20090221515A1 (en) * 2004-09-02 2009-09-03 Viswajanani Jitendra Sattigeri Monosaccharide derivatives
US20100113371A9 (en) * 2004-12-22 2010-05-06 Ranbaxy Laboratories Limited Inc. Derivatives Of Pentose Monosaccharides As Anti-Inflammatory Compounds
EP1915160A2 (fr) * 2005-07-22 2008-04-30 Ranbaxy Laboratories Limited Derives de monosaccharides pour le traitement de copd et de la rhinite allergique
AU2006313430B2 (en) 2005-11-08 2012-09-06 Ranbaxy Laboratories Limited Process for (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
US20080114031A1 (en) * 2006-03-29 2008-05-15 Sattigeri Viswajanani J Monosaccharide derivatives
US7790689B2 (en) * 2006-05-30 2010-09-07 Ranbaxy Laboratories Limited Monosaccharide derivatives
US20080300196A1 (en) * 2006-10-03 2008-12-04 Ashwani Kumar Verma Monosaccharide derivatives
CN105367612A (zh) * 2014-08-13 2016-03-02 中国药科大学 龙脷叶由来天然产物丁基2-脱氧-3，6-脱水-β-D-阿拉伯糖呋喃糖苷的全合成方法
US20220356150A1 (en) * 2021-04-30 2022-11-10 Evoco Limited Biobased diisocyanates, and process for preparation of same
WO2024135721A1 (fr) * 2022-12-21 2024-06-27 田辺三菱製薬株式会社 Procédé de production d'un intermédiaire de production, intermédiaire de production obtenu à partir de celui-ci et procédé de production d'un intermédiaire d'acide nucléique artificiel réticulé faisant appel à celui-ci

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2715121A (en) 1950-09-09 1955-08-09 American Home Prod Alkyl sugar derivatives and their preparation
US4056322A (en) 1973-12-14 1977-11-01 Strategic Medical Research Corporation Preparation of ethers of monosaccharides
DE2936240A1 (de) * 1979-09-07 1981-03-26 Bayer Ag, 51373 Leverkusen Verfahren zur herstellung bekannter und neuer 6-amino-6-desoxy-2,3-0-isopropyliden-(alpha)-l-sorbofuranose-derivate sowie neue zwischenprodukte des verfahrens
US4735934A (en) 1981-02-17 1988-04-05 Greenwich Pharmaceuticals Incorporated Method of therapeutically treating a warm blooded animal afflicted with an autoimmune disease
US4996195A (en) 1989-01-09 1991-02-26 Greenwich Pharmaceuticals Inc. Derivatives of α,D-glucofuranose or α,D-allofuranose and intermediates for preparing these derivatives
US5298494A (en) 1989-01-09 1994-03-29 Greenwich Pharmaceuticals Incorporated Monosaccharides having anti-proliferation and anti-inflammatory activity, compositions and uses thereof
US5010058A (en) 1989-06-22 1991-04-23 501 Greenwich Pharmaceuticals Incorporated 3,5,6-substituted derivatives of 1,2-O-isopropylidene-α,D-glucofuranose and intermediates for preparing these derivatives
US5192746A (en) 1990-07-09 1993-03-09 Tanabe Seiyaku Co., Ltd. Cyclic cell adhesion modulation compounds
IL100833A0 (en) 1991-02-20 1992-09-06 Greenwich Pharma Method for synthesis of ethereally substituted blocked monosaccharides
US5360792A (en) 1991-12-20 1994-11-01 Greenwich Pharmaceuticals Incorporated Anti-proliferative and anti-inflammatory compounds: 5- or 6-deoxy hexose monosaccharides having a saturated nitrogen-containing heterocycle at the 5- or 6-position bound through the nitrogen atom
US5360794A (en) 1992-08-03 1994-11-01 Medicarb Inc. Disubstituted and deoxy disubstituted derivatives of α-D-mannofuranosides and β-L-gulofuranosides having anti-inflammatory and anti-proliferative activity
US5367062A (en) 1992-08-21 1994-11-22 Medicarb Inc. Disubstituted and deoxydisubstituted derivatives of α-d-lyxofuranosides having anti-inflammatory and anti-proliferative activity
US5508387A (en) * 1993-08-04 1996-04-16 Glycomed Incorporated Selectin binding glycopeptides
WO1995010296A1 (fr) * 1993-10-12 1995-04-20 Glycomed Incorporated Banque de glyco-peptides permettant d'identifier des inhibiteurs d'adherence intercellulaire
US5637570A (en) 1995-05-09 1997-06-10 Chemora Pharmochem Disubstituted and trisubstituted derivatives of 2,3:4,6-di-O-isopropylidene-α-L-xylo-2-hexulofuranosonic acid having anti-cancer, anti-inflammatory and anti-proliferative activity
WO1997015585A1 (fr) * 1995-10-26 1997-05-01 Kanebo, Ltd. Derives de la fucose, medicaments dont ils forment le principe actif, et leurs intermediaires de fabrication
US5824657A (en) 1997-03-18 1998-10-20 Cubist Pharmaceuticals, Inc. Aminoacyl sulfamides for the treatment of hyperproliferative disorders

Also Published As

Publication number Publication date
SK9962001A3 (en) 2002-02-05
AU767948B2 (en) 2003-11-27
DE60011568T2 (de) 2005-08-18
HRP20010527A2 (en) 2002-08-31
YU50101A (sh) 2005-07-19
PA8489601A1 (es) 2000-09-29
SK284568B6 (sk) 2005-06-02
MY122723A (en) 2006-04-29
BR0007489A (pt) 2002-01-02
HK1041006A1 (en) 2002-06-28
HUP0200097A2 (hu) 2002-05-29
PT1144425E (pt) 2004-10-29
MA25679A1 (fr) 2003-04-01
JP2002534529A (ja) 2002-10-15
DK1144425T3 (da) 2004-10-18
NZ512851A (en) 2004-02-27
CN1254478C (zh) 2006-05-03
IL144274A0 (en) 2002-05-23
NZ527482A (en) 2005-02-25
HRP20010527B1 (en) 2005-06-30
AR033939A1 (es) 2004-01-21
EP1144425B1 (fr) 2004-06-16
CN1343212A (zh) 2002-04-03
CZ20012541A3 (cs) 2002-02-13
IL144274A (en) 2007-05-15
US6329344B1 (en) 2001-12-11
ID30259A (id) 2001-11-15
ES2223447T3 (es) 2005-03-01
CA2359980A1 (fr) 2000-07-20
TR200102031T2 (tr) 2001-12-21
DE60011568D1 (de) 2004-07-22
WO2000042053A1 (fr) 2000-07-20
AU1886000A (en) 2000-08-01
EP1144425A1 (fr) 2001-10-17
HK1041006B (zh) 2005-02-04
CO5170511A1 (es) 2002-06-27
HUP0200097A3 (en) 2003-03-28
ATE269349T1 (de) 2004-07-15

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