DK1103546T3 - Fremgangsmåde til fremstilling af pyridinderivater - Google Patents
Fremgangsmåde til fremstilling af pyridinderivaterInfo
- Publication number
- DK1103546T3 DK1103546T3 DK00125665T DK00125665T DK1103546T3 DK 1103546 T3 DK1103546 T3 DK 1103546T3 DK 00125665 T DK00125665 T DK 00125665T DK 00125665 T DK00125665 T DK 00125665T DK 1103546 T3 DK1103546 T3 DK 1103546T3
- Authority
- DK
- Denmark
- Prior art keywords
- compound
- formula
- chem
- reacting
- substituents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99123686 | 1999-11-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1103546T3 true DK1103546T3 (da) | 2004-02-23 |
Family
ID=8239482
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00125665T DK1103546T3 (da) | 1999-11-29 | 2000-11-23 | Fremgangsmåde til fremstilling af pyridinderivater |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6303790B1 (de) |
| EP (1) | EP1103546B1 (de) |
| JP (1) | JP3403164B2 (de) |
| KR (1) | KR100371121B1 (de) |
| CN (1) | CN1176908C (de) |
| AT (1) | ATE252559T1 (de) |
| CA (1) | CA2326815C (de) |
| DE (1) | DE60006054T2 (de) |
| DK (1) | DK1103546T3 (de) |
| ES (1) | ES2208206T3 (de) |
| JO (1) | JO2252B1 (de) |
| MX (1) | MXPA00011670A (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1394150T3 (da) * | 1999-02-24 | 2011-03-21 | Hoffmann La Roche | 4-phenylpyridinderivater og deres anvendelse som NK-1-receptorantagonister |
| ATE253561T1 (de) * | 1999-11-29 | 2003-11-15 | Hoffmann La Roche | 2-(3,5-bis-trifluoromethyl-phenyl)-n-methyl-n-( - morpholin-4-yl-4-o-tolyl-pyridin-3-yl)- isobutyramid |
| TWI287003B (en) * | 2000-07-24 | 2007-09-21 | Hoffmann La Roche | 4-phenyl-pyridine derivatives |
| TWI259180B (en) * | 2000-08-08 | 2006-08-01 | Hoffmann La Roche | 4-Phenyl-pyridine derivatives |
| US20030083345A1 (en) * | 2001-07-10 | 2003-05-01 | Torsten Hoffmann | Method of treatment and/or prevention of brain, spinal or nerve injury |
| ATE375980T1 (de) * | 2002-02-12 | 2007-11-15 | Smithkline Beecham Corp | Nicotinamide und deren verwendung als p38 inhibitoren |
| US7288658B2 (en) | 2003-07-15 | 2007-10-30 | Hoffmann-La Roche Inc. | Process for preparation of pyridine derivatives |
| WO2006002860A1 (en) | 2004-07-06 | 2006-01-12 | F. Hoffmann-La Roche Ag | Process for preparing carboxamide pyridine derivatives used as intermediates in the synthesis of nk-1 receptor antagonists |
| EP2281556A1 (de) | 2005-02-25 | 2011-02-09 | F. Hoffmann-La Roche AG | Tablette mit verbesserter Arzneimittelsubstanzdispersibilität |
| PL1928427T3 (pl) | 2005-09-23 | 2010-06-30 | Hoffmann La Roche | Nowa postać dawkowana |
| GB0808747D0 (en) | 2008-05-14 | 2008-06-18 | Glaxo Wellcome Mfg Pte Ltd | Novel compounds |
| US8426450B1 (en) | 2011-11-29 | 2013-04-23 | Helsinn Healthcare Sa | Substituted 4-phenyl pyridines having anti-emetic effect |
| WO2015000033A1 (en) | 2013-07-02 | 2015-01-08 | Eustralis Pharmaceuticals Limited (Trading As Pressura Neuro) | Method for preventing and/or treating chronic traumatic encephalopathy-ii |
| CN104003933A (zh) * | 2014-05-14 | 2014-08-27 | 上海应用技术学院 | 一种含氟基团的3-（吡啶基-2-亚胺）丙酸乙酯类似物的制备方法 |
| CN105061303A (zh) * | 2015-08-03 | 2015-11-18 | 成都欣捷高新技术开发有限公司 | 一种制备奈妥吡坦关键中间体n-甲基-4-(2-甲基苯基)-6-(4-甲基-1-哌嗪基)-3-吡啶胺的新方法 |
| CN105732488B (zh) * | 2016-03-28 | 2018-02-16 | 大连理工大学 | 一种吡啶‑2‑甲酸脱羧合成2‑(2‑氯乙氧基)乙氧基吡啶醚化合物的方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4745123A (en) | 1986-02-18 | 1988-05-17 | Warner-Lambert Company | Substituted tetrahydro-3-pyridine-carboxylic acid, ester, and amide cholinergic agents |
| DK1394150T3 (da) | 1999-02-24 | 2011-03-21 | Hoffmann La Roche | 4-phenylpyridinderivater og deres anvendelse som NK-1-receptorantagonister |
-
2000
- 2000-11-20 US US09/716,538 patent/US6303790B1/en not_active Expired - Lifetime
- 2000-11-23 DE DE60006054T patent/DE60006054T2/de not_active Expired - Lifetime
- 2000-11-23 EP EP00125665A patent/EP1103546B1/de not_active Expired - Lifetime
- 2000-11-23 DK DK00125665T patent/DK1103546T3/da active
- 2000-11-23 ES ES00125665T patent/ES2208206T3/es not_active Expired - Lifetime
- 2000-11-23 CA CA002326815A patent/CA2326815C/en not_active Expired - Lifetime
- 2000-11-23 JO JO2000186A patent/JO2252B1/en active
- 2000-11-23 AT AT00125665T patent/ATE252559T1/de active
- 2000-11-24 KR KR10-2000-0070272A patent/KR100371121B1/ko active IP Right Grant
- 2000-11-27 MX MXPA00011670A patent/MXPA00011670A/es active IP Right Grant
- 2000-11-28 CN CNB001283839A patent/CN1176908C/zh not_active Expired - Lifetime
- 2000-11-28 JP JP2000360682A patent/JP3403164B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JO2252B1 (en) | 2004-10-07 |
| US6303790B1 (en) | 2001-10-16 |
| CN1297887A (zh) | 2001-06-06 |
| DE60006054D1 (de) | 2003-11-27 |
| CN1176908C (zh) | 2004-11-24 |
| EP1103546A1 (de) | 2001-05-30 |
| ATE252559T1 (de) | 2003-11-15 |
| EP1103546B1 (de) | 2003-10-22 |
| MXPA00011670A (es) | 2002-08-20 |
| CA2326815C (en) | 2009-08-25 |
| KR20010051922A (ko) | 2001-06-25 |
| DE60006054T2 (de) | 2004-07-22 |
| JP2001151755A (ja) | 2001-06-05 |
| JP3403164B2 (ja) | 2003-05-06 |
| KR100371121B1 (ko) | 2003-02-06 |
| ES2208206T3 (es) | 2004-06-16 |
| CA2326815A1 (en) | 2001-05-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1103546T3 (da) | Fremgangsmåde til fremstilling af pyridinderivater | |
| ATE82966T1 (de) | Pyridincarboxamid-derivate und ihre verwendung als fungizides mittel. | |
| BR9910326A (pt) | Processo para preeparar isoxazóis, composto, processo para preparar compostos, uso de compostos, e, processo para preparar tioéteres | |
| DE60208364D1 (de) | Chinolinderivate mit einer azolylgruppe und chinazolinderivate | |
| DE69201058D1 (de) | Perhydroisoindol derivate und ihre herstellung. | |
| ATE119774T1 (de) | Imidazopyridinderivate und ihre verwendung. | |
| DK0918776T3 (da) | Totalsyntese af antitumor acylfulvener | |
| DE69119013D1 (de) | Benzen-, Pyridin-, Pyrimidinderivat | |
| DE60014043D1 (de) | Flouride von 4-substituierten piperidin-derivaten | |
| ES2192584T3 (es) | Derivado pirimidinilpirazol. | |
| NZ221699A (en) | Pyridazinone derivatives; pharmaceutical compositions and intermediates | |
| DK1209151T3 (da) | 4-substituerede piperidinderivativer | |
| DK0806413T3 (da) | 2-substituerede viatmin D3-derivater | |
| ATE143354T1 (de) | N-alkoxymethylbenzamid-derivate und verfahren zu ihrer herstellung und ihre verwendung zur herstellung von benzamid-derivaten | |
| DE69612611T2 (de) | Triazin-derivate | |
| DK0873327T3 (da) | Fremgangsmåde til fremstilling af 2-chlor-5-chlormethyl-thiazol | |
| ATE245147T1 (de) | Substituierte aminochinazolinon (thion) derivate | |
| ATE127449T1 (de) | Anilinderivate und verfahren zu ihrer herstellung. | |
| ATE234315T1 (de) | Medikamente gegen trhombocytopenie | |
| KR920012096A (ko) | 아스타크산틴 중간체 | |
| DE59308651D1 (de) | 2-perhalogenalkyl-substituierte benzimidazole, ihre herstellung und ihre verwendung als schädlingsbekämpfungsmittel | |
| ES2077697T3 (es) | Derivados de 1-fenoxicarbonil-2-pirrolidinona y agentes nootropicos. | |
| TH36764A (th) | สารฆ่าเชื้อรา 2-เมทธอกซีเบนโซฟีโนน | |
| TH42384A (th) | อนุพันธ์ d-โปรไลน์ | |
| KR940014354A (ko) | 신규2-페녹시피리미딘유도체,그의제조방법및제초제로서의그의용도 |