DK1100768T3 - Fremgangsmåde til fremstilling af R-(-)-carnitin - Google Patents

Fremgangsmåde til fremstilling af R-(-)-carnitin

Info

Publication number
DK1100768T3
DK1100768T3 DK99936972T DK99936972T DK1100768T3 DK 1100768 T3 DK1100768 T3 DK 1100768T3 DK 99936972 T DK99936972 T DK 99936972T DK 99936972 T DK99936972 T DK 99936972T DK 1100768 T3 DK1100768 T3 DK 1100768T3
Authority
DK
Denmark
Prior art keywords
yield
compound
carnitine
conversion
cyano
Prior art date
Application number
DK99936972T
Other languages
Danish (da)
English (en)
Inventor
Fabio Giannessi
Maria Ornella Tinti
Angelis Francesco De
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of DK1100768T3 publication Critical patent/DK1100768T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
DK99936972T 1998-07-31 1999-07-27 Fremgangsmåde til fremstilling af R-(-)-carnitin DK1100768T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI001796A IT1301977B1 (it) 1998-07-31 1998-07-31 Procedimento per la preparazione di r-(-)-carnitina
PCT/IT1999/000241 WO2000006532A2 (en) 1998-07-31 1999-07-27 Process for the preparation of r-(-)-carnitine

Publications (1)

Publication Number Publication Date
DK1100768T3 true DK1100768T3 (da) 2003-02-03

Family

ID=11380580

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99936972T DK1100768T3 (da) 1998-07-31 1999-07-27 Fremgangsmåde til fremstilling af R-(-)-carnitin

Country Status (12)

Country Link
US (1) US6316667B2 (ko)
EP (1) EP1100768B1 (ko)
JP (1) JP2002521469A (ko)
KR (1) KR100614545B1 (ko)
AT (1) ATE225329T1 (ko)
AU (1) AU5193499A (ko)
DE (1) DE69903320T2 (ko)
DK (1) DK1100768T3 (ko)
ES (1) ES2184488T3 (ko)
IT (1) IT1301977B1 (ko)
PT (1) PT1100768E (ko)
WO (1) WO2000006532A2 (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6288239B1 (en) * 2000-09-19 2001-09-11 Board Of Trustees Operating Michigan State University 5-trityloxymethyl-oxazolidinones and process for the preparation thereof
ES2360096T3 (es) * 2002-08-06 2011-05-31 Pharmasset, Inc. Procedimientos de preparación de nucleosidos de 1,3-dioxolano.
CN100335457C (zh) * 2005-09-08 2007-09-05 上海交通大学 3－位手性羟基被保护的3，4－二羟基丁酸酯及其制备方法
KR100846673B1 (ko) 2006-03-22 2008-07-16 엔자이텍 주식회사 엘-카르니틴의 제조방법
CN105801572B (zh) * 2016-05-12 2018-11-06 山东罗欣药业集团恒欣药业有限公司 一种利伐沙班的制备方法
CN106749073B (zh) * 2016-11-08 2019-06-18 山东裕欣药业有限公司 一种利奈唑胺的制备方法
CN116655481B (zh) * 2023-06-14 2023-11-28 海南卓科制药有限公司 一种工业化合成左卡尼汀的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2710688B2 (ja) * 1990-10-09 1998-02-10 鐘淵化学工業株式会社 ４―ブロモ―３―ヒドロキシ酪酸エステル誘導体の製造法
IT1256705B (it) * 1992-12-21 1995-12-12 Sigma Tau Ind Farmaceuti Procedimento per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione.
US5473104A (en) * 1994-09-13 1995-12-05 Neurocrine Biosciences, Inc. Process for the preparation of L-carnitine

Also Published As

Publication number Publication date
IT1301977B1 (it) 2000-07-20
DE69903320D1 (de) 2002-11-07
WO2000006532A2 (en) 2000-02-10
EP1100768B1 (en) 2002-10-02
PT1100768E (pt) 2003-02-28
ES2184488T3 (es) 2003-04-01
DE69903320T2 (de) 2003-06-18
EP1100768A2 (en) 2001-05-23
ITMI981796A0 (it) 1998-07-31
ATE225329T1 (de) 2002-10-15
US20010031892A1 (en) 2001-10-18
US6316667B2 (en) 2001-11-13
KR20010071884A (ko) 2001-07-31
JP2002521469A (ja) 2002-07-16
WO2000006532A3 (en) 2000-05-11
ITMI981796A1 (it) 2000-01-31
AU5193499A (en) 2000-02-21
KR100614545B1 (ko) 2006-08-25

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