DK109891A - 3-(2-chlorethyl)quinazolin-2,4-dioner samt fremgangsmaade til fremstilling deraf - Google Patents

3-(2-chlorethyl)quinazolin-2,4-dioner samt fremgangsmaade til fremstilling deraf Download PDF

Info

Publication number
DK109891A
DK109891A DK109891A DK109891A DK109891A DK 109891 A DK109891 A DK 109891A DK 109891 A DK109891 A DK 109891A DK 109891 A DK109891 A DK 109891A DK 109891 A DK109891 A DK 109891A
Authority
DK
Denmark
Prior art keywords
chlorethyl
diones
quinazoline
procedures
preparing
Prior art date
Application number
DK109891A
Other languages
English (en)
Other versions
DK109891D0 (da
Inventor
Victor T Bandurco
Charles F Schwender
Robert Falotico
Alfonso J Tobia
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of DK109891D0 publication Critical patent/DK109891D0/da
Publication of DK109891A publication Critical patent/DK109891A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96Two oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK109891A 1985-09-30 1991-06-10 3-(2-chlorethyl)quinazolin-2,4-dioner samt fremgangsmaade til fremstilling deraf DK109891A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/782,241 US4711883A (en) 1985-09-30 1985-09-30 Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1H,3H) diones, methods of preparation, compositions and method of use

Publications (2)

Publication Number Publication Date
DK109891D0 DK109891D0 (da) 1991-06-10
DK109891A true DK109891A (da) 1991-06-10

Family

ID=25125457

Family Applications (3)

Application Number Title Priority Date Filing Date
DK465086A DK162988C (da) 1985-09-30 1986-09-29 Substituerede 3-(4-phenyl-1-piperazinyl)ethylquinazolin-2,4-(1h,3h)dioner, fremstilling deraf samt praeparater indeholdende samme
DK109891A DK109891A (da) 1985-09-30 1991-06-10 3-(2-chlorethyl)quinazolin-2,4-dioner samt fremgangsmaade til fremstilling deraf
DK911135A DK113591D0 (da) 1985-09-30 1991-06-13 3-oe2-chlorethylaaquinazolin-2,4-dioner samt fremgangsmaade til fremstilling deraf

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK465086A DK162988C (da) 1985-09-30 1986-09-29 Substituerede 3-(4-phenyl-1-piperazinyl)ethylquinazolin-2,4-(1h,3h)dioner, fremstilling deraf samt praeparater indeholdende samme

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK911135A DK113591D0 (da) 1985-09-30 1991-06-13 3-oe2-chlorethylaaquinazolin-2,4-dioner samt fremgangsmaade til fremstilling deraf

Country Status (15)

Country Link
US (1) US4711883A (da)
EP (1) EP0219259A3 (da)
JP (1) JPS62111970A (da)
KR (1) KR870003098A (da)
AU (1) AU583949B2 (da)
CA (1) CA1290334C (da)
DK (3) DK162988C (da)
ES (1) ES2001809A6 (da)
FI (1) FI863910A (da)
GR (1) GR862452B (da)
HU (1) HUT43590A (da)
IL (1) IL80184A0 (da)
NO (1) NO863870L (da)
PT (1) PT83458B (da)
ZA (1) ZA867424B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL90879A0 (en) * 1988-09-02 1990-02-09 Janssen Pharmaceutica Nv 3-piperidinyl-indazole derivatives,their preparation and antihypertensive compositions containing them
PL166839B1 (en) * 1990-04-24 1995-06-30 Dresden Arzneimittel Method of obtaining novel 3-(mercaptoalkyl)-quinazolino-(1h,3h)-diones-2,4
IE913473A1 (en) * 1990-10-15 1992-04-22 Fujisawa Pharmaceutical Co Quinazoline derivatives and their preparation
KR100817538B1 (ko) * 2006-07-05 2008-03-27 한국화학연구원 신규 치환된―1h―퀴나졸린―2,4―디온 유도체, 이의제조방법 및 이를 함유하는 약학적 조성물
NZ595263A (en) 2009-02-26 2013-06-28 Compositions, synthesis, and methods of utilizing arylpiperazine derivatives
EP3180318B1 (en) * 2014-08-11 2019-02-20 Hydra Biosciences, Inc. Quinazoline-2,4(1h,3h)-dione derivatives as trcp5 modulators for the treatment of neuropsychiatric disorders
CN111848528B (zh) * 2019-04-29 2022-03-11 北京嘉林药业股份有限公司 一种预防和/或治疗癌症的化合物及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU612466A (en) * 1966-05-26 1967-11-30 Miles Laboratories Inc. V Product and process
US3819630A (en) * 1972-08-21 1974-06-25 R Parcell 3-(1-piperazinylalkyl)-2,4-quinazolinedione compounds and methods for their production
JPS58159480A (ja) * 1982-03-17 1983-09-21 Chugai Pharmaceut Co Ltd 新規なフエニルピペラジン誘導体
JPS60222467A (ja) * 1984-04-17 1985-11-07 Mitsubishi Chem Ind Ltd キナゾリン誘導体およびそれらの酸付加塩
JPS6187675A (ja) * 1984-10-05 1986-05-06 Mitsubishi Chem Ind Ltd キナゾリン誘導体およびその酸付加塩
JPS61161268A (ja) * 1985-01-08 1986-07-21 Mitsubishi Chem Ind Ltd フエニルピペラジン誘導体
US4639518A (en) * 1984-09-24 1987-01-27 Ortho Pharmaceutical Corporation Substituted quinazolinediones

Also Published As

Publication number Publication date
ZA867424B (en) 1988-04-27
DK109891D0 (da) 1991-06-10
DK465086D0 (da) 1986-09-29
NO863870D0 (no) 1986-09-29
EP0219259A3 (en) 1988-01-20
EP0219259A2 (en) 1987-04-22
PT83458B (en) 1988-10-31
DK113591A (da) 1991-06-13
AU6321186A (en) 1987-04-02
AU583949B2 (en) 1989-05-11
PT83458A (en) 1986-10-01
FI863910A (fi) 1987-03-31
HUT43590A (en) 1987-11-30
NO863870L (no) 1987-03-31
CA1290334C (en) 1991-10-08
DK162988C (da) 1992-06-01
JPS62111970A (ja) 1987-05-22
DK465086A (da) 1987-03-31
KR870003098A (ko) 1987-04-15
GR862452B (en) 1987-01-27
DK162988B (da) 1992-01-06
US4711883A (en) 1987-12-08
IL80184A0 (en) 1986-12-31
ES2001809A6 (es) 1988-06-16
FI863910A0 (fi) 1986-09-29
DK113591D0 (da) 1991-06-13

Similar Documents

Publication Publication Date Title
DK165249C (da) Imidazooe4,5-baaquinolin-2-thionderivater samt fremgangsmaade til fremstilling deraf
DK363086D0 (da) Fremgangsmaade til fremme af dyrs vaekst samt praeparat til anvendelse dertil
DK382785A (da) Alfa-(o-chlorphenyl)-aminomethylen-beta-formylaminopropionitril, fremgangsmaade til fremstilling af dette samt anvendelse af dette til fremstilling af 2-methyl-4-amino-5-formylaminomethyl-pyrimidin
DK173686D0 (da) Heterocykliske forbindelser samt fremgangsmaade til fremstilling heraf
DK346889D0 (da) Heteropolysaccharid bm07, fremgangsmaade til fremstilling deraf samt anvendelse deraf
DK109891D0 (da) 3-(2-chlorethyl)quinazolin-2,4-dioner samt fremgangsmaade til fremstilling deraf
DK88989D0 (da) Substituerede pyrimidiner, fremgangsmaade og mellemprodukter til deres fremstilling samt deres anvendelse
DK60386A (da) Alfa-amylaseenzym, fremgangsmaade til fremstilling deraf samt fremgangsmaade til hydrolyse af stivelse
DK115685D0 (da) Prespap samt fremgangsmaade til fremstilling deraf
DK436388D0 (da) Substituerede pyrimidiner, fremgangsmaader til deres fremstilling samt deres anvendelse
ATE48275T1 (de) Cardiotonische heterocyclocarbonyl- und acetylthiazolone.
DK540887D0 (da) Iminooxazolidiner, fremgangsmaade til deres fremstilling samt anvendelse deraf
DK548086D0 (da) Nitroanthracycliner, fremgangsmaade til deres fremstilling samt deres anvendelse
DE3664770D1 (de) Cardiotonic quinazoline derivatives
DK380787A (da) Decahydro-2-naphthylalkylaminer, fremgangsmaade til deres fremstilling samt deres anvendelse
DK504786D0 (da) Peptidforbindelser samt fremgangsmaade til fremstilling heraf
DK404587D0 (da) 5-deoxy-5-flourkanamycin b-derivater samt fremgangsmaader til fremstilling deraf
DK554885A (da) Krystallinsk zirconiumphosphat, samt fremgangsmaade til fremstilling af dette
DK47387D0 (da) Acylerede sulfonylquanidiner, fremstilling og anvendelse deraf, samt mellemprodukter til deres fremstilling og fremstilling af disse
DK366786A (da) Maaler, samt fremgangsmaade til samling af denne
DK703688A (da) Substituerede pyrimidiner, fremgangsmaade til deres fremstilling samt deres anvendelse
DK571285D0 (da) Amidin-benzodiazepiner, fremgangsmaade til anvendelse deraf samt mellemprodukter
DK522785A (da) Syntetisk krystallinsk molekylsigte, fremgangsmaade til fremstilling af denne samt anvendelse af denne
DK519086D0 (da) Substituerede 1,1,2-triphenylbut-1-ener, fremgangsmaade til deres fremstilling samt deres anvendelse
DK181289D0 (da) Substituerede pyrimidiner, fremgangsmaade til deres fremstilling samt deres anvendelse

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment