IL80184A0 - Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1h,3h)diones,their preparation and pharmaceutical compositions containing them - Google Patents
Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1h,3h)diones,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL80184A0 IL80184A0 IL80184A IL8018486A IL80184A0 IL 80184 A0 IL80184 A0 IL 80184A0 IL 80184 A IL80184 A IL 80184A IL 8018486 A IL8018486 A IL 8018486A IL 80184 A0 IL80184 A0 IL 80184A0
- Authority
- IL
- Israel
- Prior art keywords
- alkylquinazolin
- diones
- piperazinyl
- phenyl
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/782,241 US4711883A (en) | 1985-09-30 | 1985-09-30 | Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1H,3H) diones, methods of preparation, compositions and method of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL80184A0 true IL80184A0 (en) | 1986-12-31 |
Family
ID=25125457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL80184A IL80184A0 (en) | 1985-09-30 | 1986-09-29 | Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1h,3h)diones,their preparation and pharmaceutical compositions containing them |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4711883A (da) |
| EP (1) | EP0219259A3 (da) |
| JP (1) | JPS62111970A (da) |
| KR (1) | KR870003098A (da) |
| AU (1) | AU583949B2 (da) |
| CA (1) | CA1290334C (da) |
| DK (3) | DK162988C (da) |
| ES (1) | ES2001809A6 (da) |
| FI (1) | FI863910A (da) |
| GR (1) | GR862452B (da) |
| HU (1) | HUT43590A (da) |
| IL (1) | IL80184A0 (da) |
| NO (1) | NO863870L (da) |
| PT (1) | PT83458B (da) |
| ZA (1) | ZA867424B (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL90879A0 (en) * | 1988-09-02 | 1990-02-09 | Janssen Pharmaceutica Nv | 3-piperidinyl-indazole derivatives,their preparation and antihypertensive compositions containing them |
| PL166839B1 (en) * | 1990-04-24 | 1995-06-30 | Dresden Arzneimittel | Method of obtaining novel 3-(mercaptoalkyl)-quinazolino-(1h,3h)-diones-2,4 |
| IE913473A1 (en) * | 1990-10-15 | 1992-04-22 | Fujisawa Pharmaceutical Co | Quinazoline derivatives and their preparation |
| KR100817538B1 (ko) * | 2006-07-05 | 2008-03-27 | 한국화학연구원 | 신규 치환된―１ｈ―퀴나졸린―２,４―디온 유도체, 이의제조방법 및 이를 함유하는 약학적 조성물 |
| NZ595263A (en) | 2009-02-26 | 2013-06-28 | Compositions, synthesis, and methods of utilizing arylpiperazine derivatives | |
| EP3180318B1 (en) * | 2014-08-11 | 2019-02-20 | Hydra Biosciences, Inc. | Quinazoline-2,4(1h,3h)-dione derivatives as trcp5 modulators for the treatment of neuropsychiatric disorders |
| CN111848528B (zh) * | 2019-04-29 | 2022-03-11 | 北京嘉林药业股份有限公司 | 一种预防和/或治疗癌症的化合物及其制备方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU612466A (en) * | 1966-05-26 | 1967-11-30 | Miles Laboratories Inc. V | Product and process |
| US3819630A (en) * | 1972-08-21 | 1974-06-25 | R Parcell | 3-(1-piperazinylalkyl)-2,4-quinazolinedione compounds and methods for their production |
| JPS58159480A (ja) * | 1982-03-17 | 1983-09-21 | Chugai Pharmaceut Co Ltd | 新規なフエニルピペラジン誘導体 |
| JPS60222467A (ja) * | 1984-04-17 | 1985-11-07 | Mitsubishi Chem Ind Ltd | キナゾリン誘導体およびそれらの酸付加塩 |
| JPS6187675A (ja) * | 1984-10-05 | 1986-05-06 | Mitsubishi Chem Ind Ltd | キナゾリン誘導体およびその酸付加塩 |
| JPS61161268A (ja) * | 1985-01-08 | 1986-07-21 | Mitsubishi Chem Ind Ltd | フエニルピペラジン誘導体 |
| US4639518A (en) * | 1984-09-24 | 1987-01-27 | Ortho Pharmaceutical Corporation | Substituted quinazolinediones |
-
1985
- 1985-09-30 US US06/782,241 patent/US4711883A/en not_active Expired - Lifetime
-
1986
- 1986-09-26 GR GR862452A patent/GR862452B/el unknown
- 1986-09-27 KR KR1019860008112A patent/KR870003098A/ko not_active Application Discontinuation
- 1986-09-29 CA CA000519319A patent/CA1290334C/en not_active Expired - Lifetime
- 1986-09-29 EP EP86307447A patent/EP0219259A3/en not_active Ceased
- 1986-09-29 NO NO863870A patent/NO863870L/no unknown
- 1986-09-29 DK DK465086A patent/DK162988C/da active
- 1986-09-29 HU HU864130A patent/HUT43590A/hu unknown
- 1986-09-29 IL IL80184A patent/IL80184A0/xx unknown
- 1986-09-29 ZA ZA867424A patent/ZA867424B/xx unknown
- 1986-09-29 PT PT83458A patent/PT83458B/pt unknown
- 1986-09-29 ES ES8602281A patent/ES2001809A6/es not_active Expired
- 1986-09-29 FI FI863910A patent/FI863910A/fi not_active IP Right Cessation
- 1986-09-29 JP JP61228509A patent/JPS62111970A/ja active Pending
- 1986-09-29 AU AU63211/86A patent/AU583949B2/en not_active Ceased
-
1991
- 1991-06-10 DK DK109891A patent/DK109891A/da not_active Application Discontinuation
- 1991-06-13 DK DK911135A patent/DK113591D0/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA867424B (en) | 1988-04-27 |
| DK109891D0 (da) | 1991-06-10 |
| DK465086D0 (da) | 1986-09-29 |
| NO863870D0 (no) | 1986-09-29 |
| EP0219259A3 (en) | 1988-01-20 |
| EP0219259A2 (en) | 1987-04-22 |
| PT83458B (en) | 1988-10-31 |
| DK113591A (da) | 1991-06-13 |
| AU6321186A (en) | 1987-04-02 |
| AU583949B2 (en) | 1989-05-11 |
| PT83458A (en) | 1986-10-01 |
| FI863910A (fi) | 1987-03-31 |
| HUT43590A (en) | 1987-11-30 |
| NO863870L (no) | 1987-03-31 |
| CA1290334C (en) | 1991-10-08 |
| DK162988C (da) | 1992-06-01 |
| JPS62111970A (ja) | 1987-05-22 |
| DK465086A (da) | 1987-03-31 |
| KR870003098A (ko) | 1987-04-15 |
| GR862452B (en) | 1987-01-27 |
| DK109891A (da) | 1991-06-10 |
| DK162988B (da) | 1992-01-06 |
| US4711883A (en) | 1987-12-08 |
| ES2001809A6 (es) | 1988-06-16 |
| FI863910A0 (fi) | 1986-09-29 |
| DK113591D0 (da) | 1991-06-13 |
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