DK1092155T3 - Fremgangsmåde til tidlig diagnose af carcinomer - Google Patents

Fremgangsmåde til tidlig diagnose af carcinomer

Info

Publication number
DK1092155T3
DK1092155T3 DK99945931T DK99945931T DK1092155T3 DK 1092155 T3 DK1092155 T3 DK 1092155T3 DK 99945931 T DK99945931 T DK 99945931T DK 99945931 T DK99945931 T DK 99945931T DK 1092155 T3 DK1092155 T3 DK 1092155T3
Authority
DK
Denmark
Prior art keywords
carcinomas
early diagnosis
procedure
overexpression
cell cycle
Prior art date
Application number
DK99945931T
Other languages
Danish (da)
English (en)
Inventor
Knebel Doeberitz Magnus Ch Von
Dimitri Spitkovsky
Original Assignee
Deutsches Krebsforsch
Von Knebel Doeberitz Magnus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsches Krebsforsch, Von Knebel Doeberitz Magnus filed Critical Deutsches Krebsforsch
Application granted granted Critical
Publication of DK1092155T3 publication Critical patent/DK1092155T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57411Specifically defined cancers of cervix
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57423Specifically defined cancers of lung

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Food Science & Technology (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK99945931T 1998-07-01 1999-07-01 Fremgangsmåde til tidlig diagnose af carcinomer DK1092155T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19829473A DE19829473C2 (de) 1998-07-01 1998-07-01 Verfahren zur frühen Diagnose von Carcinomen
PCT/DE1999/002094 WO2000001845A2 (fr) 1998-07-01 1999-07-01 Methode de diagnostic precoce de carcinomes

Publications (1)

Publication Number Publication Date
DK1092155T3 true DK1092155T3 (da) 2003-03-24

Family

ID=7872684

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99945931T DK1092155T3 (da) 1998-07-01 1999-07-01 Fremgangsmåde til tidlig diagnose af carcinomer

Country Status (23)

Country Link
US (2) US6709832B1 (fr)
EP (1) EP1092155B1 (fr)
JP (1) JP3404020B2 (fr)
KR (1) KR100646193B1 (fr)
CN (1) CN1209627C (fr)
AT (1) ATE230487T1 (fr)
AU (1) AU749769B2 (fr)
BR (1) BRPI9912227B8 (fr)
CA (1) CA2336153C (fr)
CZ (1) CZ292076B6 (fr)
DE (2) DE19829473C2 (fr)
DK (1) DK1092155T3 (fr)
ES (1) ES2190820T3 (fr)
HK (1) HK1038609A1 (fr)
HU (1) HUP0102744A2 (fr)
IL (1) IL140550A (fr)
MX (1) MXPA00012852A (fr)
NO (1) NO328685B1 (fr)
PL (1) PL198623B1 (fr)
RU (1) RU2217761C2 (fr)
SK (1) SK284056B6 (fr)
TR (1) TR200003903T2 (fr)
WO (1) WO2000001845A2 (fr)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7306926B2 (en) * 1998-07-01 2007-12-11 Mtm Laboratories Ag Method for detecting carcinomas in a solubilized cervical body sample
AUPP991199A0 (en) * 1999-04-21 1999-05-13 University Of Sydney, The Methods for diagnosing pre-cancerous and cancerous conditions
DE10006033B4 (de) * 2000-02-10 2005-11-10 Professor Dr. Magnus von Knebel Doeberitz Chirurgische Universitätsklinik Sektion für Molekulare Diagnostik und Therapie Immunisierung eines Individuums gegen Carcinome und ihre Vorstufen
US20060057651A1 (en) * 2000-12-08 2006-03-16 Bowdish Katherine S Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
US9249229B2 (en) 2000-12-08 2016-02-02 Alexion Pharmaceuticals, Inc. Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
US7408041B2 (en) 2000-12-08 2008-08-05 Alexion Pharmaceuticals, Inc. Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
AUPR201500A0 (en) * 2000-12-11 2001-01-11 Biosceptre Pty Ltd Methods for identifying pre-neoplastic and neoplastic states in mammals
DE10063179A1 (de) * 2000-12-18 2002-06-20 Bayer Ag Verfahren zur spezifischen Detektion von Tumorzellen und ihren Vorstufen in Gebärmutterhalsabstrichen durch simultane Messung von mindestens zwei verschiedenen molekularen Markern
ES2320421T3 (es) 2001-01-17 2009-05-22 Intreat Pty Limited Anticuerpos para el diagnostico de un receptor p2x7 no funcional y el tratamiento de canceres y otras afecciones.
EP1369694A1 (fr) 2002-04-09 2003-12-10 MTM Laboratories AG Procédé de discrimination entre des métaplasies et des lésions néoplastiques ou préneoplastiques
DK1388734T3 (da) * 2002-08-01 2004-05-03 Mtm Lab Ag Metode til opløsningsbaseret diagnose
EP1422526A1 (fr) 2002-10-28 2004-05-26 MTM Laboratories AG Procédé ameliorée de diagnostic des dysplasies
WO2004070062A2 (fr) * 2003-02-04 2004-08-19 Wyeth Compositions et techniques de diagnostic et de traitement de cancers
ATE458830T1 (de) * 2003-02-26 2010-03-15 Sysmex Corp Verfahren zur untersuchung einer zelle
DE60300339T2 (de) * 2003-08-25 2006-04-13 Mtm Laboratories Ag Verfahren zum Nachweis von Karzinomen in solubilisierten zervikalen Körperproben
KR100882249B1 (ko) * 2004-03-24 2009-02-06 트리패스 이미징, 인코포레이티드 자궁경부 질환의 검사 방법 및 조성물
DE602005024964D1 (de) 2004-05-31 2011-01-05 Sysmex Corp Verfahren zur beurteilung der malignität einer säuger-krebszelle
EP1628135A1 (fr) * 2004-08-20 2006-02-22 MTM Laboratories AG Procédé pour la détection d'états médicalement pertinants dans des échantillons LBC solubilisés
US7892750B1 (en) * 2004-12-23 2011-02-22 University Of Notre Dame Du Lac Cathepsin E as a marker of colon cancer
JP4766969B2 (ja) 2005-09-14 2011-09-07 シスメックス株式会社 組織性質判定装置
US7972776B2 (en) * 2005-11-15 2011-07-05 Oncohealth Corporation Protein chips for HPV detection
US8075884B2 (en) 2006-01-12 2011-12-13 Alexion Pharmaceuticals, Inc. Antibodies to OX-2/CD200 and uses thereof
WO2008043145A1 (fr) * 2006-10-10 2008-04-17 Biosceptre International Limited Hybridomes produisant des anticorps dirigés contre le récepteur p2x7 non fonctionnel
US20100003704A1 (en) * 2008-06-13 2010-01-07 Shuling Cheng IN SITU detection of early stages and late stages HPV infection
US8968995B2 (en) * 2008-11-12 2015-03-03 Oncohealth Corp. Detection, screening, and diagnosis of HPV-associated cancers
JP5111902B2 (ja) * 2007-03-14 2013-01-09 シスメックス株式会社 癌の診断支援装置
EP2028600B1 (fr) 2007-08-24 2016-10-26 Sysmex Corporation Système de support de diagnostic pour cancer, support de diagnostic pour procédé pour fournir des informations sur un cancer, et produit de programme informatique
NZ583896A (en) 2007-09-14 2011-05-27 Biosceptre Int Ltd Purinergic (p2x) receptors in extra-cellular body fluid
ES2619681T3 (es) * 2007-09-14 2017-06-26 Biosceptre (Aust) Pty Ltd Novedosos epítopos P2X7
ES2610225T3 (es) 2008-07-04 2017-04-26 Biosceptre (Aust) Pty Ltd Péptidos y epítopos anti P2X7
JP2012526286A (ja) 2009-05-07 2012-10-25 オンコヘルス コーポレーション ヒトパピローマウイルス(hpv)およびhpv関連癌の初期段階および後期段階の検出、スクリーニング、および診断のための高度または≧cin2の同定
WO2011020155A1 (fr) 2009-08-20 2011-02-24 Biosceptre International Limited Anticorps anti-récepteur p2x7 et fragments de ceux-ci
EP3321285B1 (fr) 2009-12-24 2019-04-24 Biosceptre (Aust) Pty Ltd Anticorps dirigés contre les récepteurs p2x7 oligomères non fonctionnels
WO2011084598A1 (fr) 2010-01-08 2011-07-14 Oncohealth Corporation Immunoessais sur le vph à base de cellule et à haut débit pour diagnostiquer et dépister des cancers associés au vph
US8900813B2 (en) 2010-08-17 2014-12-02 Medical Diagnostic Laboratories, Llc CIP2A as a biomarker in detection of cervical cancer
ES2656971T3 (es) 2010-09-10 2018-03-01 Biosceptre (Aust) Pty Ltd Tratamientos para el cáncer en animales de compañía con un anticuerpo anti P2X7
US9551700B2 (en) 2010-12-20 2017-01-24 Milagen, Inc. Device and methods for the detection of cervical disease
BR112013033974A2 (pt) 2011-07-01 2017-02-14 Biosceptre Int Ltd terapia de combinação
US10527526B2 (en) 2011-11-03 2020-01-07 Tripath Imaging, Inc. Methods and compositions for preparing samples for immunostaining
US20140329230A1 (en) * 2011-11-15 2014-11-06 University Of Miami Methods for detecting human papillomavirus and providing prognosis for head and neck squamous cell carcinoma
US11761963B2 (en) 2017-09-27 2023-09-19 Alexion Pharmaceuticals, Inc. Biomarker signature for predicting tumor response to anti-CD200 therapy
WO2019234176A1 (fr) 2018-06-07 2019-12-12 Universitaet Des Saarlandes Nouveaux biomarqueurs pour le diagnostic du carcinome
CN108893534A (zh) * 2018-06-26 2018-11-27 华中科技大学鄂州工业技术研究院 泛癌症诊断标记物
RU2707884C1 (ru) * 2018-10-03 2019-12-02 федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) (ФГАОУ ВО Первый МГМУ им. И.М. Сеченова Минздрава России (Се Способ ранней диагностики почечно-клеточной карциномы по наличию антител к зрительному аррестину
FR3088640A1 (fr) 2018-10-14 2020-05-22 Smart Diagnostix Pharma Nouveau polypeptide se liant specifiquement a la proteine p16
CN111257565A (zh) * 2018-12-03 2020-06-09 上海细胞治疗集团有限公司 一种衰老细胞的检测试剂盒及其检测方法
CN113295683A (zh) * 2021-05-24 2021-08-24 烟台海关技术中心 过氧化苯甲酰检测方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281061A (en) * 1979-07-27 1981-07-28 Syva Company Double antibody for enhanced sensitivity in immunoassay
US5268463A (en) * 1986-11-11 1993-12-07 Jefferson Richard A Plant promoter α-glucuronidase gene construct
ES2201064T3 (es) 1992-10-16 2004-03-16 Cold Spring Harbor Laboratory Transposicion del complejo de ciclina y usos relacionados del mismo.
AU5694694A (en) * 1992-12-02 1994-06-22 Denis F. Hochstrasser A method for detecting growing cells using translationally controlled tumor protein p21
US5543291A (en) * 1993-01-29 1996-08-06 Dana Farber Cancer Institute Method of detecting carcinoma
US6316208B1 (en) * 1994-01-07 2001-11-13 Memorial Sloan-Kettering Cancer Center Methods for determining isolated p27 protein levels and uses thereof
EP0702730A4 (fr) * 1994-03-18 1997-05-07 Univ Utah Res Found Mutations de lignees germinales dans le gene mts et procede permettant de detecter une predisposition au cancer dans le gene mts
US5763190A (en) * 1994-09-21 1998-06-09 The Trustees Of The University Of Pennsylvania Methods for the identification of compounds capable of inducing the nuclear translocation of a receptor complex comprising the glucocoticoid receptor type II and viral protein R interacting protein
US6033847A (en) * 1995-02-06 2000-03-07 St. Jude Children's Research Hospital InK4c-p18 and InK4d-p19, inhibitors of cyclin-dependent kinases CDK4 and CDK6, and uses thereof
US5976799A (en) 1996-03-21 1999-11-02 The Board Of Trustees Of The University Of Arkansas Early detection of ovarian carcinoma using P16 gene products
US5851797A (en) * 1996-06-19 1998-12-22 Regeneron Pharmaceuticals, Inc. Tie ligand-3, methods of making and uses thereof
US5858683A (en) * 1996-08-30 1999-01-12 Matritech, Inc. Methods and compositions for the detection of cervical cancer
WO2000024245A1 (fr) * 1998-10-28 2000-05-04 President And Fellows Of Harvard College REGULATION DE L'ACTIVITE DES CELLULES TH2 PAR MODULATION DE L'ACTIVITE DE NFATp ET DE NFAT4

Also Published As

Publication number Publication date
AU5848799A (en) 2000-01-24
WO2000001845A3 (fr) 2000-02-17
ATE230487T1 (de) 2003-01-15
RU2217761C2 (ru) 2003-11-27
IL140550A0 (en) 2002-02-10
IL140550A (en) 2005-08-31
HUP0102744A2 (hu) 2001-11-28
US20030152993A1 (en) 2003-08-14
EP1092155B1 (fr) 2003-01-02
CZ292076B6 (cs) 2003-07-16
DE19829473C2 (de) 2000-08-10
SK20312000A3 (sk) 2001-10-08
CN1307681A (zh) 2001-08-08
CA2336153A1 (fr) 2000-01-13
WO2000001845A2 (fr) 2000-01-13
EP1092155A2 (fr) 2001-04-18
PL198623B1 (pl) 2008-07-31
KR100646193B1 (ko) 2006-11-17
KR20010074632A (ko) 2001-08-04
NO20006681D0 (no) 2000-12-28
CN1209627C (zh) 2005-07-06
BRPI9912227A (pt) 2001-04-24
NO20006681L (no) 2001-02-26
CA2336153C (fr) 2005-12-20
AU749769B2 (en) 2002-07-04
BRPI9912227B1 (pt) 2013-08-20
TR200003903T2 (tr) 2001-06-21
CZ20004922A3 (cs) 2001-07-11
MXPA00012852A (es) 2003-09-11
US6709832B1 (en) 2004-03-23
ES2190820T3 (es) 2003-08-16
DE19829473A1 (de) 2000-01-13
SK284056B6 (sk) 2004-08-03
DE59903915D1 (de) 2003-02-06
PL345407A1 (en) 2001-12-17
NO328685B1 (no) 2010-04-26
WO2000001845B1 (fr) 2000-04-20
JP3404020B2 (ja) 2003-05-06
BRPI9912227B8 (pt) 2021-07-06
JP2002519681A (ja) 2002-07-02
HK1038609A1 (en) 2002-03-22

Similar Documents

Publication Publication Date Title
DK1092155T3 (da) Fremgangsmåde til tidlig diagnose af carcinomer
HK1092219A1 (en) Method for detecting neoplastic disorders in a solubilized body sample
DE60228557D1 (de) Candida-nachweis
TR200001460T2 (tr) Çok düşük estrojen dozları kullanılarak menopoz sonrası kadınların tedavisine yönelik metodlar
EP1687283A4 (fr) Procede et composition servant a determiner fk 506
ES2133813T3 (es) Cadenas de lamininas: diagnostico y uso terapeutico.
EP1708745A4 (fr) Anticorps pour des souches oncogenes du hpv et leurs methodes d'utilisation
WO2000008464A3 (fr) Procede permettant d'evaluer les defenses immunitaires du sang, trousse d'essai correspondante
ATE258310T1 (de) Testverfahren für collagenpeptid
SE9604815D0 (sv) A metod of diagnosis
WO2000035950A3 (fr) Reactifs et methodes utiles pour la detection des pathologies du sein
FR2816410B1 (fr) Necessaire de detection de la proteine esm-1 et procede de detection mettant en oeuvre ledit necessaire
ATE285581T1 (de) Assay-verfahren
DE60013093D1 (de) Methoden und kits zum sequenzieren von polypeptiden
EA200200435A1 (ru) Анализ лептина
DK1386160T3 (da) Fremgangsmåde til påvisning af blodcelle-antigener og antistoffer rettet mod disse
EP2071338A3 (fr) Protéines liées au diabète humain
DE50007635D1 (de) Verfahren zur diagnose von sjögren-syndrom
ES2191173T3 (es) Anticuerpos monoclonales contra un complejo de act humana y una proteasa de serina.
SE0002835D0 (sv) Method and kit for production of monoclonal antibodies
SE9602234D0 (sv) A novel diagnostic method utilizing ECP, and reagents to be used in the methods
DK1171157T3 (da) Anvendelse af glucose-6-phosphat-isomerase og antistoffer derimod til diagnosticering og behandling af arthritis, og test for anti-arthritis-forbindelser
IL141858A0 (en) Diagnostic method for detecting disturbances of the pancreas
EP1702984A3 (fr) Méthode pour la détection du cancer de la prostate
WO2001006226A3 (fr) Procede pour determiner l'activite de proliferation de cellules