ES2191173T3 - Anticuerpos monoclonales contra un complejo de act humana y una proteasa de serina. - Google Patents

Anticuerpos monoclonales contra un complejo de act humana y una proteasa de serina.

Info

Publication number
ES2191173T3
ES2191173T3 ES97911202T ES97911202T ES2191173T3 ES 2191173 T3 ES2191173 T3 ES 2191173T3 ES 97911202 T ES97911202 T ES 97911202T ES 97911202 T ES97911202 T ES 97911202T ES 2191173 T3 ES2191173 T3 ES 2191173T3
Authority
ES
Spain
Prior art keywords
monoclonal antibodies
serine protease
act
antibodies against
human act
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97911202T
Other languages
English (en)
Inventor
Christa Hubner-Parajsz
Hartmut Schetters
Rosemarie Kientsch-Engel
Thomas Meier
Martin Kaufmann
Andreas Gallusser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7808241&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2191173(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Application granted granted Critical
Publication of ES2191173T3 publication Critical patent/ES2191173T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/38—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57434—Specifically defined cancers of prostate

Abstract

EL OBJETO DE LA INVENCION SON ANTICUERPOS MONOCLONALES CONTRA UN COMPLEJO FORMADO POR UNA ACT HUMANA Y UNA SERINPROTEASAS, PREFERIBLEMENTE LA ACT - PSA, QUE NO PRESENTA NINGUNA REACCION CRUZADA POR UNION A LA ACT HUMANA LIBRE NO ACOMPLEJADO, NI AL PSA LIBRE NO COMPLEJADO, ASI COMO LOS PROCEDIMIENTOS DE DIAGNOSTICOS PARA LA DETECCION DE COMPLEJOS DE SERINPROTEASA - ACT EN PARTICULAR PSA - ACT, UTILIZANDO ESTOS ANTICUERPOS MONOCLONALES.
ES97911202T 1996-10-09 1997-10-09 Anticuerpos monoclonales contra un complejo de act humana y una proteasa de serina. Expired - Lifetime ES2191173T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19641560A DE19641560A1 (de) 1996-10-09 1996-10-09 Monoklonale Antikörper gegen einen Komplex aus humanem ACT und einer Serinprotease

Publications (1)

Publication Number Publication Date
ES2191173T3 true ES2191173T3 (es) 2003-09-01

Family

ID=7808241

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97911202T Expired - Lifetime ES2191173T3 (es) 1996-10-09 1997-10-09 Anticuerpos monoclonales contra un complejo de act humana y una proteasa de serina.

Country Status (10)

Country Link
US (2) US6630350B1 (es)
EP (1) EP0929579B1 (es)
JP (1) JP3589303B2 (es)
AT (1) ATE230761T1 (es)
AU (1) AU725332B2 (es)
CA (1) CA2267660A1 (es)
DE (2) DE19641560A1 (es)
ES (1) ES2191173T3 (es)
IL (1) IL129236A (es)
WO (1) WO1998015580A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2329851T3 (es) * 1998-06-01 2009-12-01 Agensys, Inc. Nuevos antigenos transmembranables expresados en canceres humano y utilizacion de los mismos.
CA2311512A1 (en) * 1999-07-24 2001-01-24 Bayer Corporation Reflex method for the detection of prostate cancer
DE10211818B4 (de) * 2002-03-16 2006-07-06 peS Gesellschaft für medizinische Diagnose-Systeme mbH Verfahren zur quantitativen Bestimmung mehrerer Analyten
US20080125582A1 (en) * 2006-10-13 2008-05-29 Bio-Rad Laboratories, Inc. Methods and compositions for stabilizing prostate specific antigen
EP3019262A1 (en) 2013-07-12 2016-05-18 Merck Patent GmbH Removal of fragments from a sample containing a target protein using activated carbon
CN104459109B (zh) * 2014-11-25 2016-03-23 成都威尔诺生物科技有限公司 一种用于酶联免疫反应的单组份tmb显色液
CN106198989B (zh) * 2016-06-29 2018-02-16 丹娜（天津）生物科技有限公司 检测前列腺特异抗原与α1‑抗糜蛋白酶复合物的试剂盒
JP7355140B2 (ja) * 2022-02-28 2023-10-03 住友ベークライト株式会社 セリンプロテアーゼの検出用または測定用試薬

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9002480D0 (sv) 1990-07-23 1990-07-23 Hans Lilja Assay of free and complexed prostate-specific antigen
DK0511050T3 (da) 1991-04-17 1997-06-09 Pierre Julien Anordningen består af mindst et element af aerodynamisk form, der er geometrisk variabelt, integrerende et system af kontrol af grænselaget
DE4322342A1 (de) * 1993-07-05 1995-02-09 Gif Ges Fuer Immunologische Fo Verfahren für die Differentialdiagnostik des Prostata-Karzinoms
EP0635575A1 (en) 1993-07-22 1995-01-25 Wallac Oy Monoclonal antibodies against epitopes found in free but not in alpha-1-antichmotrypsin complexed prostate specific antigen
US5599677A (en) * 1993-12-29 1997-02-04 Abbott Laboratories Immunoassays for prostate specific antigen
IL121659A (en) * 1996-10-25 2000-07-16 Bayer Ag Method for determining CPSA in a blood sample
US5856182A (en) 1996-11-18 1999-01-05 Beckman Coulter, Inc. Monoclonal antibodies specific for the PSA-ACT complex

Also Published As

Publication number Publication date
US20030073141A1 (en) 2003-04-17
JP3589303B2 (ja) 2004-11-17
AU725332B2 (en) 2000-10-12
JP2001502669A (ja) 2001-02-27
DE59709109D1 (de) 2003-02-13
IL129236A (en) 2002-08-14
IL129236A0 (en) 2000-02-17
AU4865997A (en) 1998-05-05
WO1998015580A1 (de) 1998-04-16
DE19641560A1 (de) 1998-04-16
ATE230761T1 (de) 2003-01-15
EP0929579B1 (de) 2003-01-08
EP0929579A1 (de) 1999-07-21
US6630350B1 (en) 2003-10-07
CA2267660A1 (en) 1998-04-16

Similar Documents

Publication Publication Date Title
IL140550A0 (en) Methods for early diagnosis of carcinomas
EP1429797A4 (en) DIAGNOSIS AND TREATMENT OF MALIGNANE NEOPLASMS
EA200300464A1 (ru) ГУМАНИЗИРОВАННОЕ АНТИТЕЛО ПРОТИВ РЕЦЕПТОРА ЛИМФОТОКСИНА-β (ВАРИАНТЫ), КОМПОЗИЦИЯ, СПОСОБ ЛЕЧЕНИЯ ИЛИ СНИЖЕНИЯ РИСКА РАЗВИТИЯ, ТЯЖЕСТИ ИЛИ ПОСЛЕДСТВИЙ НЕОПЛАЗИИ У ЧЕЛОВЕКА, ВЫДЕЛЕННАЯ НУКЛЕИНОВАЯ КИСЛОТА (ВАРИАНТЫ), КЛЕТКА КЛЕТОЧНОЙ ЛИНИИ
HK1074670A1 (en) Sets of digital antibodies directed against short epitopes, and methods using same
NO20054351L (no) Monoklonalt antistoff og hybridom som produserer dette
RS80704A (en) ANTI- av?6.ANTIBODIES
MXPA04006517A (es) Conjugados que comprenden un anticuerpo especifico para el dominio ed-b de fibronectina y sus usos para la deteccion y tratamiento de tumores.
HUP9802212A2 (hu) Humán terápiában alkalmazható rekombináns anti-CD4-ellenanyagok
BG101077A (en) New peptides
ATE464374T1 (de) Assay zum schnellen nachweis vom humanen aktivierten protein c und hochspezifischer monoklonaler antikörper dagegen
NO331148B1 (no) Anvendelse av et monoklonalt eller polyklonalt antistoff, samt fremgangsmate og kit for in vitro diagnose.
DE69433663D1 (de) Antikörper gegen menschliches prostatspezifisches drüsenkallikrein
DE69937835D1 (de) Antikörper für apoptosemarker und anwendungsverfahren
WO2004043223A3 (en) Compositions and methods for the diagnosis and treatment of sepsis
UA94211C2 (ru) Выделенное полностью человеческое моноклональное cd3 антитело
ES2191173T3 (es) Anticuerpos monoclonales contra un complejo de act humana y una proteasa de serina.
SE9604815D0 (sv) A metod of diagnosis
WO1997029199A3 (en) Prostate specific antigen peptides and uses thereof
AU3392901A (en) Proteins
DE69938778D1 (de) Verwendung des urokinase plasminogen aktivator reztastasen
WO2002021133A3 (en) Methods of detecting cancer based on prostasin
TR200103432T2 (tr) Engelleyici monoklonal VLA-1 antikoru ve enflamasyonlu hastalıkların tedavisinde kullanımı.
DE60014064D1 (de) Einetenascin-c isoform als marker für neoplasmen
MX9708697A (es) Metodo para diagnostico cancer de prostata.
SE0002835D0 (sv) Method and kit for production of monoclonal antibodies