DK1083902T3 - Nye galeniske præparatformer af meloxicam til oral administrering - Google Patents

Nye galeniske præparatformer af meloxicam til oral administrering

Info

Publication number
DK1083902T3
DK1083902T3 DK99915690T DK99915690T DK1083902T3 DK 1083902 T3 DK1083902 T3 DK 1083902T3 DK 99915690 T DK99915690 T DK 99915690T DK 99915690 T DK99915690 T DK 99915690T DK 1083902 T3 DK1083902 T3 DK 1083902T3
Authority
DK
Denmark
Prior art keywords
meloxicam
oral administration
galenic formulations
novel galenic
novel
Prior art date
Application number
DK99915690T
Other languages
Danish (da)
English (en)
Inventor
Thomas Bock
Paul Saegmueller
Peter Sieger
Dietrich Tuerck
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Application granted granted Critical
Publication of DK1083902T3 publication Critical patent/DK1083902T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK99915690T 1998-03-27 1999-03-23 Nye galeniske præparatformer af meloxicam til oral administrering DK1083902T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98105569A EP0945134A1 (fr) 1998-03-27 1998-03-27 Nouvelles formes galeniques du meloxicam pour administration par voie orale
PCT/EP1999/001949 WO1999049867A1 (fr) 1998-03-27 1999-03-23 Nouvelles formes galeniques de meloxicame a administrer par voie orale

Publications (1)

Publication Number Publication Date
DK1083902T3 true DK1083902T3 (da) 2004-03-29

Family

ID=8231652

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99915690T DK1083902T3 (da) 1998-03-27 1999-03-23 Nye galeniske præparatformer af meloxicam til oral administrering

Country Status (25)

Country Link
US (1) US6869948B1 (fr)
EP (2) EP0945134A1 (fr)
JP (1) JP3639532B2 (fr)
KR (1) KR100589299B1 (fr)
CN (1) CN1163231C (fr)
AR (1) AR016197A1 (fr)
AT (1) ATE254920T1 (fr)
AU (1) AU762322C (fr)
BR (1) BR9909192A (fr)
CA (1) CA2326517C (fr)
DE (1) DE59907871D1 (fr)
DK (1) DK1083902T3 (fr)
ES (1) ES2212547T3 (fr)
HK (1) HK1034183A1 (fr)
HU (1) HUP0101246A3 (fr)
IL (2) IL137652A0 (fr)
NO (1) NO326852B1 (fr)
NZ (1) NZ507382A (fr)
PL (1) PL192967B1 (fr)
PT (1) PT1083902E (fr)
TR (1) TR200002786T2 (fr)
TW (1) TWI236914B (fr)
UY (1) UY25441A1 (fr)
WO (1) WO1999049867A1 (fr)
ZA (1) ZA200004178B (fr)

Families Citing this family (45)

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CA2352430C (fr) 1998-12-01 2008-11-18 Novo Nordisk A/S Nouvelle composition pharmaceutique et procede de preparation
AU1548001A (en) 1999-11-24 2001-06-04 Wakamoto Pharmaceutical Co., Ltd. Ophthalmic aqueous preparation
EP1303273A1 (fr) 2000-05-26 2003-04-23 Novo Nordisk A/S Nouvelle composition pharmaceutique et son procede de preparation
AU2000249111A1 (en) * 2000-05-30 2001-12-11 Dr. Reddy's Research Foundation New pharmaceutical composition and the process for its preparation
US20020035107A1 (en) 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
DE10030345A1 (de) * 2000-06-20 2002-01-10 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen
US7120656B1 (en) 2000-10-04 2006-10-10 Marvell International Ltd. Movable tap finite impulse response filter
EP1367994A2 (fr) * 2001-02-27 2003-12-10 Ranbaxy Laboratories Limited Comprimes a dissolution rapide d'inhibiteurs de l'enzyme cyclooxygenase-2
EP1250921A1 (fr) * 2001-04-21 2002-10-23 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Comprimé de meloxicam à désintégration rapide
DE10161077A1 (de) 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
EP1348436A1 (fr) * 2002-03-30 2003-10-01 Boehringer Ingelheim International GmbH Suppositoires de meloxicam
GB0209257D0 (en) * 2002-04-23 2002-06-05 Novartis Ag Organic compounds
DE10232113A1 (de) * 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
DE10250081A1 (de) * 2002-10-25 2004-05-13 Boehringer Ingelheim Vetmedica Gmbh Wasserlösliche Meloxicam Granulate
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
LT1562567T (lt) 2002-11-22 2017-08-25 Grünenthal GmbH Pasirinktų analgetikų ir cox-ii slopiklių derinys
US8512727B2 (en) * 2003-03-03 2013-08-20 Alkermes Pharma Ireland Limited Nanoparticulate meloxicam formulations
US20100297252A1 (en) 2003-03-03 2010-11-25 Elan Pharma International Ltd. Nanoparticulate meloxicam formulations
NZ542852A (en) * 2003-03-17 2008-09-26 Japan Tobacco Inc Pharmaceutical compositions of CETP inhibitors
KR100620239B1 (ko) * 2004-01-05 2006-09-13 신일제약주식회사 용해도 및 안정성이 향상된 경구투여용 멜록시캄 고형제조성물
EP1568369A1 (fr) * 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Utilisation du meloxicam pour le traitement de maladies respiratoires des porcs
DE102004021281A1 (de) 2004-04-29 2005-11-24 Boehringer Ingelheim Vetmedica Gmbh Verwendung von Meloxicam-Formulierungen in der Veterinärmedizin
DE102004030409A1 (de) * 2004-06-23 2006-01-26 Boehringer Ingelheim Vetmedica Gmbh Neue Verwendung von Meloxicam in der Veterinärmedizin
US20060025408A1 (en) * 2004-08-02 2006-02-02 Sundaram Venkataraman Process for the preparation of crystalline form-1 of 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide
PL3056492T3 (pl) 2004-10-08 2022-03-21 Abbvie Inc. Sól megluminowa i jej krystaliczne postaci leku (delafloksacyna)
HU227359B1 (en) * 2004-12-18 2011-04-28 Egis Gyogyszergyar Nyilvanosan Mikodi Ruszvunytarsasag Process for producing meloxicam and meloxicam potassium salt of high purity
PL1824493T3 (pl) 2004-12-06 2009-01-30 Janssen Pharmaceutica Nv Zawiesina zawierająca meloksykam do podawania doustnego
CA2597956C (fr) 2005-02-17 2013-07-09 Velcera Pharmaceuticals Administration par voie transmuqueuse de compositions medicamenteuses pour le traitement et la prevention de troubles chez les animaux
CA2614468A1 (fr) * 2005-07-15 2007-01-25 Teva Pharmaceutical Industries Ltd. Nouveau procede de granulation et granule produit par ce procede
WO2007039417A1 (fr) * 2005-09-30 2007-04-12 Boehringer Ingelheim Vetmedica Gmbh Préparation pharmaceutique qui contient du méloxicam
US7572641B2 (en) 2005-11-22 2009-08-11 Teva Pharmaceutical Industries Ltd. Pharmaceutical compositions comprising meloxicam and methods of their preparation
US20070154542A1 (en) * 2005-12-30 2007-07-05 Cogentus Pharmaceuticals, Inc. Oral pharmaceutical formulations containing non-steroidal anti-inflammatory drugs and acid inhibitors
KR100791160B1 (ko) * 2006-05-30 2008-01-02 조선대학교산학협력단 멜록시캄의 에탄올아민염 및 이를 함유하는 약제학적조성물
US20070281927A1 (en) * 2006-06-06 2007-12-06 Shanthakumar Tyavanagimatt Anti-inflammatory and analgesic compositions and related methods
WO2009094155A1 (fr) * 2008-01-22 2009-07-30 Thar Pharmaceuticals Études in vivo de formes cristallines de méloxicam
TR200809200A1 (tr) 2008-12-01 2009-12-21 Sanovel �La� Sanay� Ve T�Caret Anon�M ��Rket� Meloksikam içeren farmasötik formülasyonlar
CA2777366C (fr) 2009-10-12 2023-11-14 Boehringer Ingelheim Vetmedica Gmbh Recipients pour compositions comprenant du meloxicam
WO2011107150A1 (fr) 2010-03-03 2011-09-09 Boehringer Ingelheim Vetmedica Gmbh Utilisation de méloxicam pour le traitement à long terme de troubles musculo-squelettiques chez les chats
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
WO2012009542A2 (fr) 2010-07-14 2012-01-19 Kansas State University Research Foundation Procédés de soulagement de la douleur chronique et d'amélioration de la performance du bétail subissant un écornage ou une castration
US20170281640A1 (en) * 2016-04-04 2017-10-05 Productos Maver, S.A. De C.V. Pharmaceutical Compositions Containing a Muscle Relaxant and a Nonsteroidal Anti-Inflammatory Drugs (NSAID)
EP3877385A1 (fr) * 2018-11-05 2021-09-15 Mylan Laboratories Ltd. Co-cristaux de méloxicam
EP3958841A1 (fr) 2019-04-22 2022-03-02 Mylan Specialty L.P. Compositions de co-cristaux de méloxicam
CA3200729A1 (fr) 2020-11-06 2022-05-12 Mylan Laboratories Ltd Composition pharmaceutique comprenant du meloxicam
CN112587497A (zh) * 2020-12-25 2021-04-02 苏州中化药品工业有限公司 一种美洛昔康混悬液胶囊剂及其制备方法

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DE2756113A1 (de) * 1977-12-16 1979-06-21 Thomae Gmbh Dr K Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
IT1207994B (it) * 1986-01-03 1989-06-01 Therapicon Srl Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche.
CA2237306C (fr) * 1995-11-13 2008-10-07 Pitmy International N.V. Supports d'administration pour medicaments analgesiques, anti-inflammatoires et antipyretiques contenant de l'oxyde nitreux et compositions pharmaceutiques contenant ces supports et ces medicaments
EP1007049A1 (fr) * 1997-08-27 2000-06-14 Hexal AG Nouvelles compositions pharmaceutiques de meloxicam presentant une solubilite et une biodisponibilite ameliorees

Also Published As

Publication number Publication date
AU762322C (en) 2004-02-12
CA2326517C (fr) 2008-06-10
HUP0101246A3 (en) 2002-08-28
NO20004823L (no) 2000-11-22
ES2212547T3 (es) 2004-07-16
NO326852B1 (no) 2009-03-02
ZA200004178B (en) 2002-04-24
IL137652A0 (en) 2001-10-31
PL192967B1 (pl) 2006-12-29
WO1999049867A1 (fr) 1999-10-07
US6869948B1 (en) 2005-03-22
EP0945134A1 (fr) 1999-09-29
TR200002786T2 (tr) 2001-01-22
BR9909192A (pt) 2000-12-05
ATE254920T1 (de) 2003-12-15
AU762322B2 (en) 2003-06-26
AU3417199A (en) 1999-10-18
JP3639532B2 (ja) 2005-04-20
UY25441A1 (es) 1999-11-17
EP1083902A1 (fr) 2001-03-21
PL342988A1 (en) 2001-07-16
JP2002509886A (ja) 2002-04-02
CN1295478A (zh) 2001-05-16
DE59907871D1 (de) 2004-01-08
CA2326517A1 (fr) 1999-10-07
PT1083902E (pt) 2004-04-30
AR016197A1 (es) 2001-06-20
HK1034183A1 (en) 2001-10-19
KR20010034698A (ko) 2001-04-25
IL137652A (en) 2006-10-05
KR100589299B1 (ko) 2006-06-14
TWI236914B (en) 2005-08-01
EP1083902B1 (fr) 2003-11-26
NZ507382A (en) 2003-08-29
NO20004823D0 (no) 2000-09-26
HUP0101246A2 (hu) 2002-05-29
CN1163231C (zh) 2004-08-25

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