DK1077935T3 - Phenylsulfonamid-phenylethylaminer, der kan anvendes som dopamin-receptorer - Google Patents

Phenylsulfonamid-phenylethylaminer, der kan anvendes som dopamin-receptorer

Info

Publication number
DK1077935T3
DK1077935T3 DK99919771T DK99919771T DK1077935T3 DK 1077935 T3 DK1077935 T3 DK 1077935T3 DK 99919771 T DK99919771 T DK 99919771T DK 99919771 T DK99919771 T DK 99919771T DK 1077935 T3 DK1077935 T3 DK 1077935T3
Authority
DK
Denmark
Prior art keywords
phenylethylamines
phenylsulfonamide
alkyl
dopamine receptors
nhcoch3
Prior art date
Application number
DK99919771T
Other languages
Danish (da)
English (en)
Inventor
Arthur Glenn Romero
Jeffrey A Leiby
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of DK1077935T3 publication Critical patent/DK1077935T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/45Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
    • C07C311/46Y being a hydrogen or a carbon atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK99919771T 1998-05-14 1999-05-07 Phenylsulfonamid-phenylethylaminer, der kan anvendes som dopamin-receptorer DK1077935T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8549398P 1998-05-14 1998-05-14
PCT/US1999/007023 WO1999058499A1 (en) 1998-05-14 1999-05-07 Phenylsulfonamide-phenylethylamines useful as dopamine receptors

Publications (1)

Publication Number Publication Date
DK1077935T3 true DK1077935T3 (da) 2004-02-16

Family

ID=22191975

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99919771T DK1077935T3 (da) 1998-05-14 1999-05-07 Phenylsulfonamid-phenylethylaminer, der kan anvendes som dopamin-receptorer

Country Status (25)

Country Link
US (1) US6103766A (zh)
EP (1) EP1077935B1 (zh)
JP (1) JP2002514623A (zh)
KR (1) KR20010043546A (zh)
CN (1) CN1152857C (zh)
AT (1) ATE253045T1 (zh)
AU (1) AU752543B2 (zh)
BR (1) BR9910405A (zh)
CA (1) CA2327345A1 (zh)
DE (1) DE69912419T2 (zh)
DK (1) DK1077935T3 (zh)
EA (1) EA002918B1 (zh)
ES (1) ES2211078T3 (zh)
HK (1) HK1036049A1 (zh)
HU (1) HUP0101746A3 (zh)
IL (1) IL139263A0 (zh)
NO (1) NO20005732L (zh)
NZ (1) NZ508152A (zh)
PL (1) PL343891A1 (zh)
PT (1) PT1077935E (zh)
SK (1) SK16242000A3 (zh)
TR (1) TR200003325T2 (zh)
TW (1) TW450954B (zh)
WO (1) WO1999058499A1 (zh)
ZA (1) ZA200005921B (zh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT971878E (pt) * 1997-02-27 2008-07-08 Takeda Pharmaceutical Compostos de amina, sua produção e utilização como inibidores da produção de amilóide beta
US6849635B2 (en) * 2001-05-07 2005-02-01 Smithkline Beecham Corporation Sulfonamides
EP1385495A4 (en) * 2001-05-07 2005-12-21 Smithkline Beecham Corp SULPHONAMIDES
JP4754570B2 (ja) 2004-10-14 2011-08-24 アボット ゲーエムベーハー ウント カンパニー カーゲー ドーパミンd3受容体の調節に応答する障害の治療に好適なアザビシクロヘプチル化合物
AU2005293698B2 (en) 2004-10-14 2011-12-15 AbbVie Deutschland GmbH & Co. KG Heterocyclic compounds suitable for treating disorders that respond to modulation of the dopamine D3 receptor
EP2371814A1 (en) 2004-10-14 2011-10-05 Abbott GmbH & Co. KG Aminoethylaromatic compounds suitable for treating disorders that respond to modulation of the dopamine D3 receptor
PE20080057A1 (es) * 2006-04-14 2008-03-10 Abbott Gmbh & Co Kg Compuestos de ariloxietilamina como agentes moduladores del receptor de dopamina d3
US8383641B2 (en) 2006-04-14 2013-02-26 Abbott Gmbh & Co. Kg Aryloxyethylamine compounds suitable for treating disorders that respond to modulation of the dopamine D3 receptor
MX2008013206A (es) 2006-04-19 2008-10-22 Abbott Gmbh & Co Kg Compuestos heterociclicos adecuados para el tratamiento de trastornos que responden a modulacion del receptor de serotonina 5ht6.
JP2009534354A (ja) 2006-04-19 2009-09-24 アボット ゲーエムベーハー ウント カンパニー カーゲー セロトニン5ht6受容体の調節に応答する障害を治療するために好適な複素環アリールスルホン類
WO2008026046A1 (en) * 2006-08-30 2008-03-06 Pfizer Products Inc. Morpholine d3 dopamine antagonists

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3574741A (en) * 1969-04-14 1971-04-13 Mead Johnson & Co Sulfonamidophenalkylamines
US5451677A (en) * 1993-02-09 1995-09-19 Merck & Co., Inc. Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity
GB9402197D0 (en) * 1994-02-04 1994-03-30 Smithkline Beecham Plc Compounds
CA2205998C (en) * 1994-11-23 2002-07-16 Neurogen Corporation Certain 4-aminomethyl-2-substituted imidazole derivatives and 2-aminomethyl-4-substituted imidazole derivatives; new classes of dopamine receptor subtype specific ligands
PL329803A1 (en) * 1996-05-11 1999-04-12 Smithkline Beecham Plc Derivatives of tetrahydroisoquinoline as modulators od dopamine d receptors
DE69734215T2 (de) * 1996-07-22 2006-06-29 Novo Nordisk A/S Verbindungen mit Wachstumshormon-freisetzenden Eigenschaften
JPH1180156A (ja) * 1997-09-04 1999-03-26 Hokuriku Seiyaku Co Ltd 1−(置換アリール)アルキル−1h−イミダゾピリジン−4−アミン誘導体

Also Published As

Publication number Publication date
TW450954B (en) 2001-08-21
US6103766A (en) 2000-08-15
EP1077935B1 (en) 2003-10-29
KR20010043546A (ko) 2001-05-25
CN1152857C (zh) 2004-06-09
HK1036049A1 (en) 2001-12-21
SK16242000A3 (sk) 2001-06-11
HUP0101746A3 (en) 2002-10-28
WO1999058499A1 (en) 1999-11-18
NO20005732D0 (no) 2000-11-13
PT1077935E (pt) 2004-03-31
CN1297431A (zh) 2001-05-30
HUP0101746A2 (hu) 2002-03-28
AU752543B2 (en) 2002-09-19
AU3741899A (en) 1999-11-29
ZA200005921B (en) 2001-11-14
EA002918B1 (ru) 2002-10-31
BR9910405A (pt) 2001-01-09
IL139263A0 (en) 2001-11-25
ATE253045T1 (de) 2003-11-15
EP1077935A1 (en) 2001-02-28
NO20005732L (no) 2000-11-13
CA2327345A1 (en) 1999-11-18
DE69912419D1 (de) 2003-12-04
EA200001184A1 (ru) 2001-04-23
NZ508152A (en) 2003-03-28
JP2002514623A (ja) 2002-05-21
PL343891A1 (en) 2001-09-10
TR200003325T2 (tr) 2001-04-20
DE69912419T2 (de) 2004-07-22
ES2211078T3 (es) 2004-07-01

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