DK1076651T3 - Substituerede sulfonylcyanamider, fremgangsmåde til fremstilling heraf og anvendelsen heraf som lægemidler - Google Patents
Substituerede sulfonylcyanamider, fremgangsmåde til fremstilling heraf og anvendelsen heraf som lægemidlerInfo
- Publication number
- DK1076651T3 DK1076651T3 DK99948554T DK99948554T DK1076651T3 DK 1076651 T3 DK1076651 T3 DK 1076651T3 DK 99948554 T DK99948554 T DK 99948554T DK 99948554 T DK99948554 T DK 99948554T DK 1076651 T3 DK1076651 T3 DK 1076651T3
- Authority
- DK
- Denmark
- Prior art keywords
- drugs
- preparation
- methods
- substituted sulfonyl
- cyanamides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/68—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19820064A DE19820064A1 (de) | 1998-05-06 | 1998-05-06 | Substituierte Sulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
| PCT/EP1999/002940 WO1999057102A1 (de) | 1998-05-06 | 1999-04-30 | Substituierte sulfonylcyanamide, verfahren zu ihrer herstellung und ihre verwendung als medikament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1076651T3 true DK1076651T3 (da) | 2005-08-15 |
Family
ID=7866747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99948554T DK1076651T3 (da) | 1998-05-06 | 1999-04-30 | Substituerede sulfonylcyanamider, fremgangsmåde til fremstilling heraf og anvendelsen heraf som lægemidler |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6573288B1 (no) |
| EP (1) | EP1076651B1 (no) |
| JP (1) | JP4546644B2 (no) |
| KR (1) | KR20010043304A (no) |
| CN (1) | CN1177829C (no) |
| AR (1) | AR016255A1 (no) |
| AT (1) | ATE293606T1 (no) |
| AU (1) | AU756844B2 (no) |
| BR (1) | BR9911009A (no) |
| CA (1) | CA2331863A1 (no) |
| DE (3) | DE19820064A1 (no) |
| DK (1) | DK1076651T3 (no) |
| ES (1) | ES2241326T3 (no) |
| HK (1) | HK1038008A1 (no) |
| HR (1) | HRP20000746A2 (no) |
| HU (1) | HU225377B1 (no) |
| ID (1) | ID28020A (no) |
| IL (1) | IL139264A (no) |
| NO (1) | NO317886B1 (no) |
| NZ (1) | NZ507964A (no) |
| PL (1) | PL344041A1 (no) |
| PT (1) | PT1076651E (no) |
| RU (1) | RU2221789C2 (no) |
| SK (1) | SK16582000A3 (no) |
| TR (1) | TR200003248T2 (no) |
| WO (1) | WO1999057102A1 (no) |
| ZA (1) | ZA200006166B (no) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030220383A1 (en) * | 2002-02-14 | 2003-11-27 | Aventis Pharma Deutschland Gmbh | Use of inhibitors of the sodium-dependent chloride/bicarbonate exchanger for the treatment of thrombotic and inflammatory disorders |
| DE10206354A1 (de) * | 2002-02-14 | 2003-08-28 | Aventis Pharma Gmbh | Verwendung von Inhibitoren des Natrium-abhängigen Chlorid-Bicarbonat-Austauschers zur Behandlung von thrombotischen und inflammatorischer Erkrankungen |
| ITTO20060575A1 (it) * | 2006-08-02 | 2008-02-03 | Univ Pisa | Inibitori di zinco proteinasi tioaril sostituiti e loro usi |
| WO2018002673A1 (en) | 2016-07-01 | 2018-01-04 | N4 Pharma Uk Limited | Novel formulations of angiotensin ii receptor antagonists |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1334092C (en) * | 1986-07-11 | 1995-01-24 | David John Carini | Angiotensin ii receptor blocking imidazoles |
| IL98319A (en) * | 1990-07-05 | 1997-04-15 | Roussel Uclaf | Sulphurous derivatives of imidazole, their preparation process, and pharmaceutical compositions containing them |
| US5126342A (en) * | 1990-10-01 | 1992-06-30 | Merck & Co., Inc. | Imidazole angiotensin ii antagonists incorporating acidic functional groups |
| CA2058198A1 (en) * | 1991-01-04 | 1992-07-05 | Adalbert Wagner | Azole derivatives, process for their preparation, and their use |
| TW215434B (no) * | 1992-03-07 | 1993-11-01 | Hoechst Ag | |
| US5310929A (en) * | 1992-08-06 | 1994-05-10 | E. I. Du Pont De Nemours And Company | Prodrugs of imidazole carboxylic acids as angiotensin II receptor antagonists |
| FR2711368B1 (fr) * | 1993-09-16 | 1996-01-05 | Roussel Uclaf | Nouveau procédé de préparation de dérivés soufrés de l'imidazole et les nouveaux intermédiaires obtenus. |
| FR2716883B1 (fr) * | 1994-03-04 | 1996-04-26 | Roussel Uclaf | Nouveaux dérivés tétrasubstitués de l'imidazole, leur préparation, nouveaux intermédiaires obtenus, leur application à titre de médicaments, compositions pharmaceutiques les renfermant. |
| DE19540995A1 (de) * | 1995-11-03 | 1997-05-07 | Hoechst Ag | Substituierte Sulfonimidamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| EP0855392A3 (de) | 1997-01-22 | 2000-01-05 | Hoechst Aktiengesellschaft | Fünfgliedrige Heterocyclen mit Biphenylsulfonylsubstitution, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE19741635A1 (de) * | 1997-09-22 | 1999-03-25 | Hoechst Marion Roussel De Gmbh | Biphenylsulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
| DE19804251A1 (de) | 1998-02-04 | 1999-08-05 | Hoechst Marion Roussel De Gmbh | Biphenylsulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
-
1998
- 1998-05-06 DE DE19820064A patent/DE19820064A1/de not_active Withdrawn
-
1999
- 1999-04-30 SK SK1658-2000A patent/SK16582000A3/sk unknown
- 1999-04-30 IL IL13926499A patent/IL139264A/en not_active IP Right Cessation
- 1999-04-30 NZ NZ507964A patent/NZ507964A/xx unknown
- 1999-04-30 RU RU2000130719/04A patent/RU2221789C2/ru not_active IP Right Cessation
- 1999-04-30 DE DE19980787T patent/DE19980787D2/de not_active Expired - Lifetime
- 1999-04-30 JP JP2000547072A patent/JP4546644B2/ja not_active Expired - Fee Related
- 1999-04-30 PL PL99344041A patent/PL344041A1/xx unknown
- 1999-04-30 BR BR9911009-1A patent/BR9911009A/pt not_active IP Right Cessation
- 1999-04-30 AT AT99948554T patent/ATE293606T1/de not_active IP Right Cessation
- 1999-04-30 AU AU59479/99A patent/AU756844B2/en not_active Ceased
- 1999-04-30 DK DK99948554T patent/DK1076651T3/da active
- 1999-04-30 WO PCT/EP1999/002940 patent/WO1999057102A1/de not_active Application Discontinuation
- 1999-04-30 CA CA002331863A patent/CA2331863A1/en not_active Abandoned
- 1999-04-30 DE DE59911949T patent/DE59911949D1/de not_active Expired - Lifetime
- 1999-04-30 HU HU0102459A patent/HU225377B1/hu not_active IP Right Cessation
- 1999-04-30 PT PT99948554T patent/PT1076651E/pt unknown
- 1999-04-30 ID IDW20002257A patent/ID28020A/id unknown
- 1999-04-30 EP EP99948554A patent/EP1076651B1/de not_active Expired - Lifetime
- 1999-04-30 US US09/674,606 patent/US6573288B1/en not_active Expired - Lifetime
- 1999-04-30 TR TR2000/03248T patent/TR200003248T2/xx unknown
- 1999-04-30 KR KR1020007012268A patent/KR20010043304A/ko not_active Application Discontinuation
- 1999-04-30 ES ES99948554T patent/ES2241326T3/es not_active Expired - Lifetime
- 1999-04-30 CN CNB998073148A patent/CN1177829C/zh not_active Expired - Fee Related
- 1999-05-04 AR ARP990102087A patent/AR016255A1/es unknown
-
2000
- 2000-10-31 ZA ZA200006166A patent/ZA200006166B/xx unknown
- 2000-11-03 NO NO20005549A patent/NO317886B1/no unknown
- 2000-11-03 HR HR20000746A patent/HRP20000746A2/hr not_active Application Discontinuation
-
2001
- 2001-11-12 HK HK01107942A patent/HK1038008A1/xx unknown
Also Published As
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