DK1053224T3 - Biphenylfulfonylcyanamider, fremgangsmåde til fremstilling deraf og anvendelse deraf som lægemiddel - Google Patents
Biphenylfulfonylcyanamider, fremgangsmåde til fremstilling deraf og anvendelse deraf som lægemiddelInfo
- Publication number
- DK1053224T3 DK1053224T3 DK99913138T DK99913138T DK1053224T3 DK 1053224 T3 DK1053224 T3 DK 1053224T3 DK 99913138 T DK99913138 T DK 99913138T DK 99913138 T DK99913138 T DK 99913138T DK 1053224 T3 DK1053224 T3 DK 1053224T3
- Authority
- DK
- Denmark
- Prior art keywords
- biphenylfulphonylcyanamides
- drug
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
- C07C311/47—Y being a hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
- C07C311/46—Y being a hydrogen or a carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19804251A DE19804251A1 (de) | 1998-02-04 | 1998-02-04 | Biphenylsulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
| PCT/EP1999/000724 WO1999040064A1 (de) | 1998-02-04 | 1999-02-04 | Biphenylsulfonylcyanamide, verfahren zu ihrer herstellung und ihre verwendung als medikament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1053224T3 true DK1053224T3 (da) | 2002-12-23 |
Family
ID=7856542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99913138T DK1053224T3 (da) | 1998-02-04 | 1999-02-04 | Biphenylfulfonylcyanamider, fremgangsmåde til fremstilling deraf og anvendelse deraf som lægemiddel |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6369069B1 (es) |
| EP (1) | EP1053224B1 (es) |
| JP (1) | JP4464559B2 (es) |
| KR (1) | KR100595353B1 (es) |
| CN (1) | CN1231465C (es) |
| AR (1) | AR016448A1 (es) |
| AT (1) | ATE222584T1 (es) |
| AU (1) | AU758154B2 (es) |
| BR (1) | BR9907667A (es) |
| CA (1) | CA2319555A1 (es) |
| DE (2) | DE19804251A1 (es) |
| DK (1) | DK1053224T3 (es) |
| ES (1) | ES2182504T3 (es) |
| HK (1) | HK1034706A1 (es) |
| HU (1) | HU224618B1 (es) |
| PL (1) | PL342453A1 (es) |
| PT (1) | PT1053224E (es) |
| RU (1) | RU2247111C2 (es) |
| TR (1) | TR200002255T2 (es) |
| WO (1) | WO1999040064A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19820064A1 (de) | 1998-05-06 | 1999-11-11 | Hoechst Marion Roussel De Gmbh | Substituierte Sulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
| US6906069B1 (en) | 1999-01-08 | 2005-06-14 | Amgen Inc. | LXR modulators |
| WO2001060818A1 (en) * | 2000-02-14 | 2001-08-23 | Tularik Inc. | Lxr modulators |
| PL360081A1 (en) | 2000-07-24 | 2004-09-06 | Bayer Cropscience Ag | Biphenyl carboxamides |
| JP4434745B2 (ja) | 2002-01-30 | 2010-03-17 | アムジェン インコーポレイテッド | 複素環式アリールスルホンアミドベンジル化合物 |
| DE10206354A1 (de) * | 2002-02-14 | 2003-08-28 | Aventis Pharma Gmbh | Verwendung von Inhibitoren des Natrium-abhängigen Chlorid-Bicarbonat-Austauschers zur Behandlung von thrombotischen und inflammatorischer Erkrankungen |
| JP5438504B2 (ja) * | 2006-04-11 | 2014-03-12 | バーテックス ファーマシューティカルズ インコーポレイテッド | 電位依存性ナトリウムチャンネル阻害剤として有用である組成物 |
| WO2018002673A1 (en) | 2016-07-01 | 2018-01-04 | N4 Pharma Uk Limited | Novel formulations of angiotensin ii receptor antagonists |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2062558A1 (en) * | 1991-03-08 | 1992-09-09 | Prasun K. Chakravarty | Heterocyclic compounds bearing acidic functional groups as angiotensin ii antagonists |
| EP0586513A1 (en) * | 1991-05-10 | 1994-03-16 | Merck & Co. Inc. | Acidic aralkyl triazole derivatives active as angiotensin ii antagonists |
| FR2716883B1 (fr) * | 1994-03-04 | 1996-04-26 | Roussel Uclaf | Nouveaux dérivés tétrasubstitués de l'imidazole, leur préparation, nouveaux intermédiaires obtenus, leur application à titre de médicaments, compositions pharmaceutiques les renfermant. |
| EP0855392A3 (de) | 1997-01-22 | 2000-01-05 | Hoechst Aktiengesellschaft | Fünfgliedrige Heterocyclen mit Biphenylsulfonylsubstitution, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE19741635A1 (de) | 1997-09-22 | 1999-03-25 | Hoechst Marion Roussel De Gmbh | Biphenylsulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
-
1998
- 1998-02-04 DE DE19804251A patent/DE19804251A1/de not_active Withdrawn
-
1999
- 1999-02-04 BR BR9907667-5A patent/BR9907667A/pt not_active Application Discontinuation
- 1999-02-04 AT AT99913138T patent/ATE222584T1/de not_active IP Right Cessation
- 1999-02-04 JP JP2000530496A patent/JP4464559B2/ja not_active Expired - Fee Related
- 1999-02-04 DK DK99913138T patent/DK1053224T3/da active
- 1999-02-04 KR KR1020007008433A patent/KR100595353B1/ko not_active IP Right Cessation
- 1999-02-04 AU AU31398/99A patent/AU758154B2/en not_active Ceased
- 1999-02-04 TR TR2000/02255T patent/TR200002255T2/xx unknown
- 1999-02-04 ES ES99913138T patent/ES2182504T3/es not_active Expired - Lifetime
- 1999-02-04 PT PT99913138T patent/PT1053224E/pt unknown
- 1999-02-04 WO PCT/EP1999/000724 patent/WO1999040064A1/de not_active Application Discontinuation
- 1999-02-04 CN CNB998026611A patent/CN1231465C/zh not_active Expired - Fee Related
- 1999-02-04 EP EP99913138A patent/EP1053224B1/de not_active Expired - Lifetime
- 1999-02-04 HU HU0102576A patent/HU224618B1/hu not_active IP Right Cessation
- 1999-02-04 RU RU2000122850/04A patent/RU2247111C2/ru not_active IP Right Cessation
- 1999-02-04 DE DE59902408T patent/DE59902408D1/de not_active Expired - Lifetime
- 1999-02-04 PL PL99342453A patent/PL342453A1/xx not_active Application Discontinuation
- 1999-02-04 US US09/601,630 patent/US6369069B1/en not_active Expired - Lifetime
- 1999-02-04 CA CA002319555A patent/CA2319555A1/en not_active Abandoned
- 1999-02-05 AR ARP990100482A patent/AR016448A1/es unknown
-
2001
- 2001-07-12 HK HK01104861A patent/HK1034706A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE222584T1 (de) | 2002-09-15 |
| AR016448A1 (es) | 2001-07-04 |
| PL342453A1 (en) | 2001-06-04 |
| BR9907667A (pt) | 2000-10-24 |
| JP2002502840A (ja) | 2002-01-29 |
| EP1053224B1 (de) | 2002-08-21 |
| TR200002255T2 (tr) | 2001-06-21 |
| JP4464559B2 (ja) | 2010-05-19 |
| AU3139899A (en) | 1999-08-23 |
| US6369069B1 (en) | 2002-04-09 |
| WO1999040064A1 (de) | 1999-08-12 |
| HUP0102576A3 (en) | 2002-12-28 |
| PT1053224E (pt) | 2002-12-31 |
| RU2247111C2 (ru) | 2005-02-27 |
| KR20010040564A (ko) | 2001-05-15 |
| CA2319555A1 (en) | 1999-08-12 |
| HUP0102576A1 (hu) | 2002-03-28 |
| CN1289321A (zh) | 2001-03-28 |
| DE59902408D1 (de) | 2002-09-26 |
| AU758154B2 (en) | 2003-03-13 |
| HU224618B1 (hu) | 2005-11-28 |
| DE19804251A1 (de) | 1999-08-05 |
| KR100595353B1 (ko) | 2006-07-03 |
| ES2182504T3 (es) | 2003-03-01 |
| CN1231465C (zh) | 2005-12-14 |
| HK1034706A1 (en) | 2001-11-02 |
| EP1053224A1 (de) | 2000-11-22 |
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