DK1050534T3 - 2,3-methanaminosyrederivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse - Google Patents

2,3-methanaminosyrederivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse

Info

Publication number
DK1050534T3
DK1050534T3 DK00401197T DK00401197T DK1050534T3 DK 1050534 T3 DK1050534 T3 DK 1050534T3 DK 00401197 T DK00401197 T DK 00401197T DK 00401197 T DK00401197 T DK 00401197T DK 1050534 T3 DK1050534 T3 DK 1050534T3
Authority
DK
Denmark
Prior art keywords
optionally substituted
alkyl
preparation
acid derivatives
aryl
Prior art date
Application number
DK00401197T
Other languages
English (en)
Inventor
Nanteuil Guillaume De
Philippe Gloanec
Tony Verbeuren
Alain Rupin
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Application granted granted Critical
Publication of DK1050534T3 publication Critical patent/DK1050534T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DK00401197T 1999-05-03 2000-05-02 2,3-methanaminosyrederivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse DK1050534T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9905601A FR2793248B1 (fr) 1999-05-03 1999-05-03 Nouveaux derives de 2,3-methano-aminoacides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
DK1050534T3 true DK1050534T3 (da) 2002-03-04

Family

ID=9545154

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00401197T DK1050534T3 (da) 1999-05-03 2000-05-02 2,3-methanaminosyrederivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse

Country Status (23)

Country Link
US (1) US6288077B1 (da)
EP (1) EP1050534B1 (da)
JP (1) JP3200053B2 (da)
KR (1) KR100439599B1 (da)
CN (1) CN1130347C (da)
AT (1) ATE210131T1 (da)
AU (1) AU763670B2 (da)
BR (1) BR0002075A (da)
CA (1) CA2308780C (da)
DE (1) DE60000036T2 (da)
DK (1) DK1050534T3 (da)
EA (1) EA002645B1 (da)
ES (1) ES2169716T3 (da)
FR (1) FR2793248B1 (da)
HK (1) HK1032237A1 (da)
HU (1) HUP0001712A3 (da)
MX (1) MXPA00004241A (da)
NO (1) NO20002314L (da)
NZ (1) NZ504298A (da)
PL (1) PL198571B1 (da)
PT (1) PT1050534E (da)
SI (1) SI1050534T1 (da)
ZA (1) ZA200002152B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6774110B2 (en) * 2001-03-19 2004-08-10 Lg Life Sciences Ltd. Orally available peptidic thrombin inhibitors
JP2003072059A (ja) * 2001-06-21 2003-03-12 Ricoh Co Ltd インクジェット記録装置及び複写機
TW200911787A (en) * 2007-07-03 2009-03-16 Astrazeneca Ab New aza-bicyclohexane compounds useful as inhibitors of thrombin
CA2727925A1 (en) * 2008-06-23 2009-12-30 Astrazeneca Ab New heterocyclic carboxamides for use as thrombin inhibitors
JP2022509366A (ja) * 2018-10-29 2022-01-20 ファーハイ ユーエス インコーポレイテッド 新規ジペプチド化合物及びその使用方法
WO2024015574A1 (en) * 2022-07-14 2024-01-18 Jnana Therapeutics Inc. Small molecule inhibitors of mammalian slc6a19 function

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4954158A (en) * 1983-08-16 1990-09-04 University Of Georgia Research Foundation, Inc. 2,3-methanoproline
FR2701951B1 (fr) * 1993-02-24 1995-06-09 Adir Nouveaux derives peptidiques de l'acide boronique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
IL112795A (en) * 1994-03-04 2001-01-28 Astrazeneca Ab Derivatives of peptides as antithrombotic drugs, their preparation, and pharmaceutical preparations containing them
US5688826A (en) * 1995-11-16 1997-11-18 Eli Lilly And Company Excitatory amino acid derivatives
NO310618B1 (no) * 1997-04-10 2001-07-30 Ono Pharmaceutical Co Kondenserte piperidinforbindelser, fremstilling og anvendelse derav, samt preparater omfattende slike forbindelser

Also Published As

Publication number Publication date
EA002645B1 (ru) 2002-08-29
CA2308780C (fr) 2003-04-22
JP2000344745A (ja) 2000-12-12
PL198571B1 (pl) 2008-06-30
US6288077B1 (en) 2001-09-11
EA200000374A3 (ru) 2001-02-26
ES2169716T3 (es) 2002-07-16
CN1277961A (zh) 2000-12-27
HUP0001712A2 (en) 2001-03-28
ATE210131T1 (de) 2001-12-15
SI1050534T1 (en) 2002-04-30
ZA200002152B (en) 2000-11-07
CN1130347C (zh) 2003-12-10
JP3200053B2 (ja) 2001-08-20
DE60000036T2 (de) 2002-07-18
HU0001712D0 (en) 2000-07-28
KR100439599B1 (ko) 2004-07-12
EP1050534B1 (fr) 2001-12-05
HK1032237A1 (en) 2001-07-13
NZ504298A (en) 2001-01-26
BR0002075A (pt) 2001-01-02
NO20002314D0 (no) 2000-05-02
HUP0001712A3 (en) 2002-02-28
MXPA00004241A (es) 2002-03-08
DE60000036D1 (de) 2002-01-17
CA2308780A1 (fr) 2000-11-03
EA200000374A2 (ru) 2000-12-25
PL339967A1 (en) 2000-11-06
PT1050534E (pt) 2002-05-31
FR2793248B1 (fr) 2001-06-29
AU763670B2 (en) 2003-07-31
AU3132500A (en) 2000-11-30
NO20002314L (no) 2000-11-06
KR20010029683A (ko) 2001-04-06
EP1050534A1 (fr) 2000-11-08
FR2793248A1 (fr) 2000-11-10

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