DK1040106T3 - Carboxylsubstituerede chromanderivater til anvendelse som beta 3 adrenoreceptor-agonister - Google Patents
Carboxylsubstituerede chromanderivater til anvendelse som beta 3 adrenoreceptor-agonisterInfo
- Publication number
- DK1040106T3 DK1040106T3 DK98963240T DK98963240T DK1040106T3 DK 1040106 T3 DK1040106 T3 DK 1040106T3 DK 98963240 T DK98963240 T DK 98963240T DK 98963240 T DK98963240 T DK 98963240T DK 1040106 T3 DK1040106 T3 DK 1040106T3
- Authority
- DK
- Denmark
- Prior art keywords
- beta
- carboxyl
- chroman derivatives
- adrenoreceptor agonists
- substituted chroman
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Peptides Or Proteins (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Detergent Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99462097A | 1997-12-19 | 1997-12-19 | |
| PCT/US1998/026735 WO1999032476A1 (en) | 1997-12-19 | 1998-12-16 | Carboxyl substituted chroman derivatives useful as beta 3 adrenoreceptor agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1040106T3 true DK1040106T3 (da) | 2002-12-02 |
Family
ID=25540853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98963240T DK1040106T3 (da) | 1997-12-19 | 1998-12-16 | Carboxylsubstituerede chromanderivater til anvendelse som beta 3 adrenoreceptor-agonister |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1040106B1 (xx) |
| JP (1) | JP2001526282A (xx) |
| KR (1) | KR20010033188A (xx) |
| CN (1) | CN1284952A (xx) |
| AT (1) | ATE222901T1 (xx) |
| AU (1) | AU749097B2 (xx) |
| BG (1) | BG104593A (xx) |
| BR (1) | BR9814302A (xx) |
| CA (1) | CA2316971A1 (xx) |
| DE (1) | DE69807523T2 (xx) |
| DK (1) | DK1040106T3 (xx) |
| ES (1) | ES2183434T3 (xx) |
| HU (1) | HUP0004565A3 (xx) |
| ID (1) | ID26524A (xx) |
| IL (1) | IL136689A0 (xx) |
| NO (1) | NO20003083L (xx) |
| NZ (1) | NZ505200A (xx) |
| PL (1) | PL341229A1 (xx) |
| PT (1) | PT1040106E (xx) |
| RU (1) | RU2223269C2 (xx) |
| SK (1) | SK9362000A3 (xx) |
| TR (1) | TR200001927T2 (xx) |
| UA (1) | UA62993C2 (xx) |
| WO (1) | WO1999032476A1 (xx) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR035605A1 (es) | 2000-12-11 | 2004-06-16 | Bayer Corp | Derivados de aminometil cromano di-sustituidos, un metodo para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la manufactura de medicamentos utiles como agonistas beta-3-adreno-receptores |
| AR035858A1 (es) * | 2001-04-23 | 2004-07-21 | Bayer Corp | Derivados de cromano 2,6-sustituidos,composiciones farmaceuticas,uso de dichos derivados para la manufactura de medicamentos utiles como agonistas adrenorreceptores beta-3 |
| EP1454899A1 (en) * | 2001-10-17 | 2004-09-08 | Kaneka Corporation | Process for preparation of (s)-alpha-halome thylpyridine methanol derivatives |
| MY147767A (en) * | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| BRPI0608353A2 (pt) | 2005-02-17 | 2009-12-01 | Wyeth Corp | derivados de indol, benzotiofeno, benzofurano e indeno cicloalquilfundidos |
| EP1803716B1 (en) * | 2005-12-28 | 2012-07-25 | Acino Pharma AG | A process for preparation of racemic nebivolol |
| US7560575B2 (en) * | 2005-12-28 | 2009-07-14 | Acino Pharma Ag | Process for preparation of racemic Nebivolol |
| ES2534336B1 (es) * | 2013-10-18 | 2016-01-28 | Artax Biopharma Inc. | Derivados de cromeno como inhibidores de la interacción TCR-Nck |
| ES2534318B1 (es) * | 2013-10-18 | 2016-01-28 | Artax Biopharma Inc. | Derivados de cromeno sustituidos por alcóxido como inhibidores de la interacción TCR-Nck |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1337429C (en) * | 1983-12-05 | 1995-10-24 | Guy Rosalia Eugene Van Lommen | Derivatives of 2,2'-iminobisethanol |
| GB8801306D0 (en) * | 1988-01-21 | 1988-02-17 | Ici Plc | Chemical compounds |
| US5451677A (en) * | 1993-02-09 | 1995-09-19 | Merck & Co., Inc. | Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity |
| ATE154935T1 (de) * | 1993-06-14 | 1997-07-15 | Pfizer | Zweite amine als antidiabetische mittel und für die behandlung von fettleibigkeit |
| GB9405019D0 (en) * | 1994-03-15 | 1994-04-27 | Smithkline Beecham Plc | Novel compounds |
| US5561142A (en) * | 1994-04-26 | 1996-10-01 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
| EP0801060A1 (en) * | 1996-04-09 | 1997-10-15 | Pfizer Inc. | Heterocyclic Beta-3 Adrenergenic Agonists |
-
1998
- 1998-12-16 AU AU18300/99A patent/AU749097B2/en not_active Ceased
- 1998-12-16 UA UA2000074336A patent/UA62993C2/uk unknown
- 1998-12-16 DK DK98963240T patent/DK1040106T3/da active
- 1998-12-16 DE DE69807523T patent/DE69807523T2/de not_active Expired - Fee Related
- 1998-12-16 CN CN98813619A patent/CN1284952A/zh active Pending
- 1998-12-16 JP JP2000525413A patent/JP2001526282A/ja not_active Withdrawn
- 1998-12-16 PL PL98341229A patent/PL341229A1/xx not_active Application Discontinuation
- 1998-12-16 CA CA002316971A patent/CA2316971A1/en not_active Abandoned
- 1998-12-16 PT PT98963240T patent/PT1040106E/pt unknown
- 1998-12-16 RU RU2000119110/04A patent/RU2223269C2/ru not_active IP Right Cessation
- 1998-12-16 SK SK936-2000A patent/SK9362000A3/sk unknown
- 1998-12-16 HU HU0004565A patent/HUP0004565A3/hu unknown
- 1998-12-16 EP EP98963240A patent/EP1040106B1/en not_active Expired - Lifetime
- 1998-12-16 KR KR1020007006572A patent/KR20010033188A/ko not_active Application Discontinuation
- 1998-12-16 TR TR2000/01927T patent/TR200001927T2/xx unknown
- 1998-12-16 WO PCT/US1998/026735 patent/WO1999032476A1/en not_active Application Discontinuation
- 1998-12-16 IL IL13668998A patent/IL136689A0/xx unknown
- 1998-12-16 ES ES98963240T patent/ES2183434T3/es not_active Expired - Lifetime
- 1998-12-16 BR BR9814302-6A patent/BR9814302A/pt not_active IP Right Cessation
- 1998-12-16 ID IDW20001393A patent/ID26524A/id unknown
- 1998-12-16 AT AT98963240T patent/ATE222901T1/de not_active IP Right Cessation
- 1998-12-16 NZ NZ505200A patent/NZ505200A/xx unknown
-
2000
- 2000-06-15 NO NO20003083A patent/NO20003083L/no not_active Application Discontinuation
- 2000-07-11 BG BG104593A patent/BG104593A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TR200001927T2 (tr) | 2001-06-21 |
| HUP0004565A2 (hu) | 2001-08-28 |
| SK9362000A3 (en) | 2001-09-11 |
| EP1040106A1 (en) | 2000-10-04 |
| ID26524A (id) | 2001-01-11 |
| DE69807523D1 (de) | 2002-10-02 |
| AU749097B2 (en) | 2002-06-20 |
| ES2183434T3 (es) | 2003-03-16 |
| HUP0004565A3 (en) | 2002-12-28 |
| KR20010033188A (ko) | 2001-04-25 |
| PT1040106E (pt) | 2002-11-29 |
| CA2316971A1 (en) | 1999-07-01 |
| JP2001526282A (ja) | 2001-12-18 |
| NO20003083L (no) | 2000-08-15 |
| RU2223269C2 (ru) | 2004-02-10 |
| ATE222901T1 (de) | 2002-09-15 |
| IL136689A0 (en) | 2001-06-14 |
| BR9814302A (pt) | 2000-10-10 |
| EP1040106B1 (en) | 2002-08-28 |
| NO20003083D0 (no) | 2000-06-15 |
| WO1999032476A1 (en) | 1999-07-01 |
| NZ505200A (en) | 2002-09-27 |
| UA62993C2 (en) | 2004-01-15 |
| PL341229A1 (en) | 2001-03-26 |
| DE69807523T2 (de) | 2003-01-09 |
| CN1284952A (zh) | 2001-02-21 |
| BG104593A (en) | 2001-09-28 |
| AU1830099A (en) | 1999-07-12 |
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