DK1035133T3 - Fusionsproteiner, der omfatter bærere, som kan inducere et dobbelt immunrespons - Google Patents

Fusionsproteiner, der omfatter bærere, som kan inducere et dobbelt immunrespons

Info

Publication number
DK1035133T3
DK1035133T3 DK00301103T DK00301103T DK1035133T3 DK 1035133 T3 DK1035133 T3 DK 1035133T3 DK 00301103 T DK00301103 T DK 00301103T DK 00301103 T DK00301103 T DK 00301103T DK 1035133 T3 DK1035133 T3 DK 1035133T3
Authority
DK
Denmark
Prior art keywords
vertebrate
immune response
fusion protein
fusion proteins
peptide
Prior art date
Application number
DK00301103T
Other languages
English (en)
Inventor
Manuel Campos
Serge Rene Martinod
Becky Ann Durtschi
Terecita Dolores Yule
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of DK1035133T3 publication Critical patent/DK1035133T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0006—Contraceptive vaccins; Vaccines against sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
DK00301103T 1999-02-17 2000-02-14 Fusionsproteiner, der omfatter bærere, som kan inducere et dobbelt immunrespons DK1035133T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12045499P 1999-02-17 1999-02-17
EP00301103A EP1035133B1 (en) 1999-02-17 2000-02-14 Fusion proteins comprising carriers that can induce a dual immune response

Publications (1)

Publication Number Publication Date
DK1035133T3 true DK1035133T3 (da) 2005-05-02

Family

ID=22390397

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00301103T DK1035133T3 (da) 1999-02-17 2000-02-14 Fusionsproteiner, der omfatter bærere, som kan inducere et dobbelt immunrespons

Country Status (10)

Country Link
US (2) US6911206B1 (da)
EP (1) EP1035133B1 (da)
JP (1) JP2000236887A (da)
AT (1) ATE286511T1 (da)
BR (1) BR0000489A (da)
CA (1) CA2297441A1 (da)
DE (1) DE60017211T2 (da)
DK (1) DK1035133T3 (da)
ES (1) ES2233284T3 (da)
PT (1) PT1035133E (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60017211T2 (de) * 1999-02-17 2005-06-02 Pfizer Products Inc., Groton Fusionsproteine mit Trägern welche eine doppelte Immunantwort induzieren
GB9919409D0 (en) * 1999-08-18 1999-10-20 Univ Oxford Brookes Baculovirus expression system
WO2004105791A2 (en) * 2003-06-02 2004-12-09 The Talwar Research Foundation Recombinant anti-lhrh vaccines
KR20070008625A (ko) * 2004-04-05 2007-01-17 화이자 프로덕츠 인코포레이티드 미세유체화된 수중유 유화액 및 백신 조성물
US8524247B2 (en) 2008-09-17 2013-09-03 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Rabies virus-based recombinant immunocontraceptive compositions and methods of use
CU23739A1 (es) * 2008-09-30 2011-12-28 Ct Ingenieria Genetica Biotech Composición farmacéutica utilizando combinaciones de variantes de la hormona liberadora de las gonadotropinas (gnrh) como inmunógeno
KR101145911B1 (ko) 2008-12-22 2012-05-15 한국화학연구원 대장균의 외막단백질 ＯｍｐＷ를 이용한 목적단백질의 표면발현 방법
KR102445330B1 (ko) * 2013-07-12 2022-09-19 더 칠드런스 호스피탈 오브 필라델피아 Ａａｖ 벡터 및 항―ａａｖ （아데노-관련 바이러스） 중화 항체에 대한 검정
CN113517025B (zh) * 2020-04-10 2022-03-18 西咸新区予果微码生物科技有限公司 一种病原体在线监测系统及方法
CN112979789B (zh) * 2021-04-14 2021-07-27 北京市农林科学院 用于检测牛传染性鼻气管炎病毒的中和抗体的阻断elisa试剂盒及其应用

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3137631A (en) 1959-12-01 1964-06-16 Faberge Inc Encapsulation in natural products
US3959457A (en) 1970-06-05 1976-05-25 Temple University Microparticulate material and method of making such material
JPS5186117A (en) 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
US4205060A (en) 1978-12-20 1980-05-27 Pennwalt Corporation Microcapsules containing medicament-polymer salt having a water-insoluble polymer sheath, their production and their use
US4452747A (en) 1982-03-22 1984-06-05 Klaus Gersonde Method of and arrangement for producing lipid vesicles
GB8314362D0 (en) 1983-05-24 1983-06-29 Celltech Ltd Polypeptide and protein products
GB2140810B (en) 1983-05-24 1987-07-08 Celltech Ltd Polypeptide and protein products, and process for their production
US4744933A (en) 1984-02-15 1988-05-17 Massachusetts Institute Of Technology Process for encapsulation and encapsulated active material system
US5008050A (en) 1984-06-20 1991-04-16 The Liposome Company, Inc. Extrusion technique for producing unilamellar vesicles
US5672347A (en) 1984-07-05 1997-09-30 Genentech, Inc. Tumor necrosis factor antagonists and their use
ATE70308T1 (de) 1984-09-12 1991-12-15 Chiron Corp Hybridpartikel-immunogene.
US4722840A (en) 1984-09-12 1988-02-02 Chiron Corporation Hybrid particle immunogens
US4921706A (en) 1984-11-20 1990-05-01 Massachusetts Institute Of Technology Unilamellar lipid vesicles and method for their formation
US4606940A (en) 1984-12-21 1986-08-19 The Ohio State University Research Foundation Small particle formation and encapsulation
IL78775A (en) 1985-05-15 1992-06-21 Biotech Australia Pty Ltd Oral vaccines
US5089396A (en) 1985-10-03 1992-02-18 Genentech, Inc. Nucleic acid encoding β chain prodomains of inhibin and method for synthesizing polypeptides using such nucleic acid
US5009956A (en) 1987-02-24 1991-04-23 Univ Minnesota Phospholipase A2-resistant liposomes
US4975420A (en) 1987-09-30 1990-12-04 University Of Saskatchewan Agents and procedures for provoking an immune response to GnRH and immuno sterilizing mammals
JPH01171489A (ja) 1987-12-26 1989-07-06 Chemo Sero Therapeut Res Inst 狂犬病ウイルス糖蛋白質をコードする遺伝子断片およびこれを用いた狂犬病ウイルス糖蛋白質の製法
US5151267A (en) 1988-07-15 1992-09-29 University Of Saskatchewan Bovine herpesvirus type 1 polypeptides and vaccines
US5585264A (en) 1988-07-15 1996-12-17 University Of Saskatchewan Nucleotide sequences encoding recombinant bovine herpesvirus type-1 GI, GIII and GIV polypeptides
JPH03502584A (ja) * 1988-08-30 1991-06-13 アプライド・リサーチ・システムス・エー・アール・エス・ホールディング・エヌ・ブイ ホルモン分泌を変化させる組換え体融合タンパク質
US4927637A (en) 1989-01-17 1990-05-22 Liposome Technology, Inc. Liposome extrusion method
US4944948A (en) 1989-02-24 1990-07-31 Liposome Technology, Inc. EGF/Liposome gel composition and method
US5403586A (en) * 1989-08-25 1995-04-04 Biotechnology Australia Ptl Ltd. LHRH-TraTp fusion proteins
US5132117A (en) 1990-01-11 1992-07-21 Temple University Aqueous core microcapsules and method for their preparation
GB9007416D0 (en) 1990-04-02 1990-05-30 Wellcome Found Expression of heterologous protein in yeast
US5238823A (en) 1990-08-22 1993-08-24 Veterinary Infectious Disease Organization Interleukin-2-leukotoxin gene fusions and uses thereof
DE69121877T2 (de) 1991-02-01 1997-04-03 Bmra Corp Bv Verfahren zur Messung der Aktivität angiotensinkonvertierenden Enzyms in biologischen Proben
US5422110A (en) * 1991-10-16 1995-06-06 University Of Saskatchewan Enhanced immunogenicity using leukotoxin chimeras
GB9201013D0 (en) 1992-01-17 1992-03-11 Animal Health Inst Vaccines
US5612360A (en) 1992-06-03 1997-03-18 Eli Lilly And Company Angiotensin II antagonists
ZA934199B (en) * 1992-06-18 1994-01-10 Akzo Nv Carrier system against gnrh
US5441736A (en) 1992-11-05 1995-08-15 University Of Saskatchewan Actinobacillus pleuropneumoniae outer membrane lipoprotein A and uses thereof
WO1994024296A2 (en) 1993-04-19 1994-10-27 University Of Saskatchewan Recombinant bovine herpesvirus type 1 vaccines
US5545523A (en) 1993-05-28 1996-08-13 Cornell Research Foundation, Inc. Methods of detecting bovine herpesvirus 1 (BHV-1) in semen by nucleic acid amplification
JP2577304B2 (ja) 1993-07-23 1997-01-29 大日本製薬株式会社 ヒト インターロイキン１活性を有するポリペプチド
US5599663A (en) 1993-08-27 1997-02-04 Brighan & Women's Hospital Angiotensin IV and analogs as regulators of fibrinolysis
EP0730465B1 (en) 1993-09-24 2001-12-12 The University Of Southern California Use of angiotensin iii and analogs thereof in tissue repair
US5786179A (en) 1994-02-28 1998-07-28 Agritech Technologies Ltd. Heterologous protein comprising avian alpha-subunit inhibin protein and methods of producing same
ATE235959T1 (de) 1994-04-15 2003-04-15 Univ Temple Methode zum einkapseln mittels eines wässrigen lösungsmittels und mikrokapseln
IL112581A0 (en) 1995-02-08 1995-05-26 Moreh Ronen Pop rivet
US6017735A (en) * 1997-01-23 2000-01-25 Marie Curie Cancer Care Materials and methods for intracellular transport and their uses
AUPO776897A0 (en) 1997-07-09 1997-07-31 Csl Limited A method of achieving production gains in livestock and agents useful for same
DE60017211T2 (de) * 1999-02-17 2005-06-02 Pfizer Products Inc., Groton Fusionsproteine mit Trägern welche eine doppelte Immunantwort induzieren

Also Published As

Publication number Publication date
PT1035133E (pt) 2005-05-31
ES2233284T3 (es) 2005-06-16
BR0000489A (pt) 2001-05-02
US6911206B1 (en) 2005-06-28
EP1035133B1 (en) 2005-01-05
EP1035133A3 (en) 2002-09-25
DE60017211D1 (de) 2005-02-10
EP1035133A2 (en) 2000-09-13
CA2297441A1 (en) 2000-08-17
US20050095258A1 (en) 2005-05-05
ATE286511T1 (de) 2005-01-15
DE60017211T2 (de) 2005-06-02
JP2000236887A (ja) 2000-09-05

Similar Documents

Publication Publication Date Title
WO2001098333A3 (en) Modification of hepatitis b core antigen
DE69529219T2 (de) Helicobacter proteine und impstoffe
WO1999010375A3 (en) Vaccine against hpv
YU48250B (sh) Postupak za pripremanje aktivne vakcine protiv lajmske bolesti
ATE325882T1 (de) Polypeptide, die mit alfalfamosaikviralen oder ilarviralen kapsiden fusioniert sind
IS4518A (is) Nýtt lyfjaform fyrir bóluefni
ATE405647T1 (de) Rekombinantes gelatin in impstoffen
HU9904549A (en) Vaccines
WO1999033868A3 (en) Human papillomavirus vaccine
PT759935E (pt) L1 de virus de papiloma recombinante
DK1035133T3 (da) Fusionsproteiner, der omfatter bærere, som kan inducere et dobbelt immunrespons
NO912825D0 (no) Fremgangsmaate for fremstilling av cokonjugate vaksiner omfattende immunogenisk protein, hiv-beslektede peptider og anioniske grupper.
CA2132742A1 (en) Synthetic Peptides and Vaccines Against Parvovirus
DE60036692D1 (de) Zusammensetzungen und methoden zur detektion einer trypanosoma cruzi infektion
NL300336I1 (nl) Vaccin tegen de bof dat een jeryl-lynn virusstam bevat
ATE283066T1 (de) Impfstoff enthaltend zytokin-induzierte heat shock proteine (hsp)
OA09653A (en) Rubella peptides
ITRM910385A0 (it) Vaccini utilizzanti eritrociti come veicoli di antigeni.
ATE530563T1 (de) Rekombinante proteine einer pakistanischen hepatitis e variante und ihre verwendung in diagnoseverfahren und impfungen
WO2001055181A3 (en) Recombinant multivalent malarial vaccines against plasmodium vivax
GB2299994A (en) Equine arteritis virus peptides antibodies and their use in a diagnostic test
CA2141670A1 (en) Peptides, analogues and mixtures thereof for detecting and eliciting antibodies to the e1 and e2 protein of rubella virus
ES1027961U (es) Soporte publicitario para carritos.
FR2818648B1 (fr) Antigenes proteiques inducteurs d'anticorps neutralisant le virus vih
NZ334582A (en) Polyprotein construct of a papillomavirus