DK1030841T3 - Fremgangsmåde til fremstilling af 1,4-dihydropyridiner og forbindelser anvendt i denne fremgangsmåde - Google Patents
Fremgangsmåde til fremstilling af 1,4-dihydropyridiner og forbindelser anvendt i denne fremgangsmådeInfo
- Publication number
- DK1030841T3 DK1030841T3 DK98955389T DK98955389T DK1030841T3 DK 1030841 T3 DK1030841 T3 DK 1030841T3 DK 98955389 T DK98955389 T DK 98955389T DK 98955389 T DK98955389 T DK 98955389T DK 1030841 T3 DK1030841 T3 DK 1030841T3
- Authority
- DK
- Denmark
- Prior art keywords
- formula
- aralkyl
- cycloalkyl
- alkyl
- iii
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK129997 | 1997-11-14 | ||
PCT/DK1998/000492 WO1999025688A1 (en) | 1997-11-14 | 1998-11-13 | Process for the preparation of 1,4-dihydropyridines and compounds used in this process |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1030841T3 true DK1030841T3 (da) | 2005-01-24 |
Family
ID=8103308
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98955389T DK1030841T3 (da) | 1997-11-14 | 1998-11-13 | Fremgangsmåde til fremstilling af 1,4-dihydropyridiner og forbindelser anvendt i denne fremgangsmåde |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1030841B1 (pt) |
AT (1) | ATE277015T1 (pt) |
AU (1) | AU1224799A (pt) |
DK (1) | DK1030841T3 (pt) |
ES (1) | ES2226185T3 (pt) |
HU (1) | HUP0100640A3 (pt) |
NO (1) | NO314900B1 (pt) |
PT (1) | PT1030841E (pt) |
RS (1) | RS49711B (pt) |
WO (1) | WO1999025688A1 (pt) |
ZA (1) | ZA9810320B (pt) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA03005885A (es) * | 2000-12-29 | 2005-04-19 | Pfizer Ltd | Procedimiento para fabricar maleato de amlodipina. |
US6653481B2 (en) | 2000-12-29 | 2003-11-25 | Synthon Bv | Process for making amlodipine |
CA2433284A1 (en) | 2000-12-29 | 2002-07-11 | Pfizer Limited | Reference standards and processes for determining the purity or stability of amlodipine maleate |
MXPA03005882A (es) | 2000-12-29 | 2005-04-19 | Pfizer Ltd | Derivado amida de amlodipina. |
CA2433191A1 (en) | 2000-12-29 | 2002-07-11 | Pfizer Limited | Aspartate derivative of amlodipine as calcium channel antagonist |
US7335380B2 (en) | 2000-12-29 | 2008-02-26 | Synthon Ip Inc. | Amlodipine free base |
ATE315026T1 (de) | 2000-12-29 | 2006-02-15 | Pfizer Ltd | Amlodipin-hemimaleat |
BR0116554A (pt) | 2000-12-29 | 2004-02-03 | Pfizer Ltd | Composto, composição farmacêutica para o tratamento da angina ou hipertensão, processo, processo para o tratamento ou prevenção da angina ou hipertensão, composição do ingrediente farmaceuticamente ativo e composição farmacêutica para o tratamento ou prevenção da angina ou hipertensão |
EP1309556B1 (en) | 2000-12-29 | 2004-11-24 | Pfizer Limited | Amlodipine fumarate |
AT5874U1 (de) | 2000-12-29 | 2003-01-27 | Bioorg Bv | Pharmazeutische zubereitungen enthaltend amlodipinmaleat |
US6680334B2 (en) | 2001-08-28 | 2004-01-20 | Pfizer Inc | Crystalline material |
ES2211317B1 (es) * | 2002-11-18 | 2005-10-16 | Finaf 92, S.A. | Compuestos intermedios para la obtencion de principios activos antihipertensivos y procedimientos correspondientes. |
CN103922996B (zh) * | 2013-01-11 | 2019-01-04 | 广东东阳光药业有限公司 | 一种药物新型中间体及其制备方法 |
CN114989072B (zh) * | 2022-05-27 | 2023-07-21 | 四川大学 | 一种不对称催化合成手性1,4-二氢吡啶化合物的方法及其应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK161312C (da) * | 1982-03-11 | 1991-12-09 | Pfizer | Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden |
JPS6191185A (ja) * | 1984-10-11 | 1986-05-09 | Sumitomo Seiyaku Kk | 新規なオキサジアゾリル−1,4−ジヒドロピリジン誘導体 |
EP0225175A3 (en) * | 1985-11-28 | 1988-12-28 | FISONS plc | Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof |
NZ280378A (en) * | 1995-11-01 | 1998-04-27 | Apotex Inc | 4-phenyl-1,4-dihydropyridine-3,5-dicarboxylic acid compounds, preparation, intermediate compounds |
-
1998
- 1998-11-11 ZA ZA9810320A patent/ZA9810320B/xx unknown
- 1998-11-13 ES ES98955389T patent/ES2226185T3/es not_active Expired - Lifetime
- 1998-11-13 AT AT98955389T patent/ATE277015T1/de not_active IP Right Cessation
- 1998-11-13 RS YUP-285/00A patent/RS49711B/sr unknown
- 1998-11-13 WO PCT/DK1998/000492 patent/WO1999025688A1/en active IP Right Grant
- 1998-11-13 EP EP98955389A patent/EP1030841B1/en not_active Expired - Lifetime
- 1998-11-13 PT PT98955389T patent/PT1030841E/pt unknown
- 1998-11-13 AU AU12247/99A patent/AU1224799A/en not_active Abandoned
- 1998-11-13 DK DK98955389T patent/DK1030841T3/da active
- 1998-11-13 HU HU0100640A patent/HUP0100640A3/hu unknown
-
2000
- 2000-05-12 NO NO20002490A patent/NO314900B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU1224799A (en) | 1999-06-07 |
WO1999025688A1 (en) | 1999-05-27 |
ES2226185T3 (es) | 2005-03-16 |
RS49711B (sr) | 2007-12-31 |
EP1030841B1 (en) | 2004-09-22 |
NO314900B1 (no) | 2003-06-10 |
NO20002490D0 (no) | 2000-05-12 |
YU28500A (sh) | 2002-10-18 |
HUP0100640A2 (hu) | 2001-07-30 |
EP1030841A1 (en) | 2000-08-30 |
NO20002490L (no) | 2000-07-13 |
ZA9810320B (en) | 2000-05-11 |
ATE277015T1 (de) | 2004-10-15 |
PT1030841E (pt) | 2005-01-31 |
HUP0100640A3 (en) | 2001-11-28 |
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