DK1003546T3 - Fremgangsmåde til behandling af patienter ramt af dissemineret sklerose ved anvendelse af konsensus interferon - Google Patents

Fremgangsmåde til behandling af patienter ramt af dissemineret sklerose ved anvendelse af konsensus interferon

Info

Publication number
DK1003546T3
DK1003546T3 DK98933344T DK98933344T DK1003546T3 DK 1003546 T3 DK1003546 T3 DK 1003546T3 DK 98933344 T DK98933344 T DK 98933344T DK 98933344 T DK98933344 T DK 98933344T DK 1003546 T3 DK1003546 T3 DK 1003546T3
Authority
DK
Denmark
Prior art keywords
treating patients
patients affected
consensus interferon
disseminated sclerosis
sclerosis
Prior art date
Application number
DK98933344T
Other languages
English (en)
Inventor
David Martin
Norman L Fischer
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of DK1003546T3 publication Critical patent/DK1003546T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DK98933344T 1997-08-15 1998-07-15 Fremgangsmåde til behandling af patienter ramt af dissemineret sklerose ved anvendelse af konsensus interferon DK1003546T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/911,893 US6013253A (en) 1997-08-15 1997-08-15 Treatment of multiple sclerosis using consensus interferon and IL-1 receptor antagonist

Publications (1)

Publication Number Publication Date
DK1003546T3 true DK1003546T3 (da) 2006-10-30

Family

ID=25431058

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98933344T DK1003546T3 (da) 1997-08-15 1998-07-15 Fremgangsmåde til behandling af patienter ramt af dissemineret sklerose ved anvendelse af konsensus interferon

Country Status (18)

Country Link
US (1) US6013253A (da)
EP (1) EP1003546B1 (da)
JP (1) JP3813440B2 (da)
KR (1) KR100415636B1 (da)
CN (1) CN1183963C (da)
AT (1) ATE338563T1 (da)
AU (1) AU741074B2 (da)
CA (1) CA2299361C (da)
CY (1) CY1107314T1 (da)
DE (1) DE69835823T2 (da)
DK (1) DK1003546T3 (da)
ES (1) ES2267188T3 (da)
HK (1) HK1030157A1 (da)
HU (1) HU229045B1 (da)
IL (2) IL134345A0 (da)
PT (1) PT1003546E (da)
TW (1) TW474817B (da)
WO (1) WO1999008702A1 (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6471961B1 (en) * 1999-02-24 2002-10-29 Edward L. Tobinick Interleukin antagonists for the treatment of neurological, retinal and muscular disorders
US20030007972A1 (en) * 1999-02-24 2003-01-09 Edward Tobinick Cytokine antagonists and other biologics for the treatment of bone metastases
US6982089B2 (en) 1999-02-24 2006-01-03 Tact Ip, Llc Cytokine antagonists for neurological and neuropsychiatric disorders
US7214658B2 (en) * 2004-07-06 2007-05-08 Tact Ip, Llc Method of delivering a TNF antagonist to the brain of a human by perispinal administration without direct intrathecal injection
US6623736B2 (en) * 2000-05-02 2003-09-23 Edward L. Tobinick Interleukin antagonists for the treatment of neurological, retinal and muscular disorders
WO2003049761A1 (en) * 2000-12-08 2003-06-19 Neuronz Limited Use of insuline-like growth factor-i for promoting remyelination of axons
DE60232880D1 (de) 2001-05-24 2009-08-20 Neuren Pharmaceuticals Ltd Gpe-analoga und peptidomimetika
US7714020B2 (en) 2001-05-24 2010-05-11 Neuren Pharmaceuticals Limited Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate
US7605177B2 (en) 2001-05-24 2009-10-20 Neuren Pharmaceuticals Limited Effects of glycyl-2 methyl prolyl glutamate on neurodegeneration
US7230167B2 (en) 2001-08-31 2007-06-12 Syngenta Participations Ag Modified Cry3A toxins and nucleic acid sequences coding therefor
SI1471974T1 (sl) * 2002-02-06 2007-12-31 Ares Trading Sa Tumorje nekrotizirajoäśi faktor, kombiniran z interferonom, pri demielinizirajoäśih boleznih
US20040141947A1 (en) * 2002-10-16 2004-07-22 Hunter Samuel F. Method for treatment of demyelinating central nervous system disease
TWI272948B (en) 2003-05-01 2007-02-11 Ares Trading Sa HSA-free stabilized interferon liquid formulations
AU2005211385B2 (en) * 2004-02-02 2008-12-11 Ambrx, Inc. Modified human growth hormone polypeptides and their uses
DE102004008168B4 (de) * 2004-02-19 2015-12-10 Voxeljet Ag Verfahren und Vorrichtung zum Auftragen von Fluiden und Verwendung der Vorrichtung
US7879320B2 (en) * 2004-05-17 2011-02-01 Ares Trading S.A. Hydrogel interferon formulations
EA010979B1 (ru) 2004-06-01 2008-12-30 Арес Трейдинг С.А. Стабилизированные жидкие препаративные формы интерферона
WO2005117948A1 (en) 2004-06-01 2005-12-15 Ares Trading S.A. Method of stabilizing proteins
TW200633718A (en) * 2004-12-16 2006-10-01 Applied Research Systems Treatment of hepatitis c in the asian population
BG66458B1 (bg) 2005-03-21 2014-10-31 Иван Иванов Средство за конкурентно инхибиране на ендогенен гама интерферон
EP1901769A2 (en) * 2005-05-02 2008-03-26 Avigen, Inc. Use of cytokine-derived peptides in treatment of pain and neurodegenerative disease
EP1917276B1 (en) 2005-08-26 2018-03-21 Ares Trading S.A. Process for the preparation of glycosylated interferon beta
CA2616479A1 (en) * 2005-09-01 2007-03-08 Ares Trading S.A. Treatment of optic neuritis
WO2007135172A2 (en) 2006-05-24 2007-11-29 Laboratoires Serono S.A. Cladribine regimen for treating multiple sclerosis
WO2009080699A2 (en) * 2007-12-20 2009-07-02 Merck Serono S.A. Peg-interferon-beta formulations
US9359421B2 (en) 2008-04-08 2016-06-07 Tigo Gmbh Suppressor of the endogenous interferon-gamma
BG66517B1 (bg) 2008-04-08 2016-02-29 Tigo Gmbh Супресор на ендогенния човешки гама - интерферон
WO2013008102A2 (en) 2011-07-14 2013-01-17 R.E.D. Laboratories N.V../ S.A. Methods and compositions for evaluating and/or treating chronic immune diseases
HUE042463T2 (hu) 2013-07-18 2019-07-29 Univ Colorado Regents Készítmény gyulladásos ízületi betegség kezelésére
BG67190B1 (bg) 2017-03-29 2020-11-16 Tigo Gmbh Анти-гама мутантен протеин срещу ендогенния човешки гама интерферон

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6936694B1 (en) * 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
US5075222A (en) * 1988-05-27 1991-12-24 Synergen, Inc. Interleukin-1 inhibitors
CA2068320C (en) * 1989-11-29 2000-10-17 Robert Hageman Production of recombinant human interleukin-1 inhibitor
WO1991017184A1 (en) * 1990-04-27 1991-11-14 The Upjohn Company Modified interleukin-1 inhibitors
US5372808A (en) * 1990-10-17 1994-12-13 Amgen Inc. Methods and compositions for the treatment of diseases with consensus interferon while reducing side effect
SG52537A1 (en) * 1990-10-17 1998-09-28 Amgen Inc Methods and compositions for the treatment of cell proliferation disorders
US5858355A (en) * 1990-12-20 1999-01-12 University Of Pittsburgh Of The Commonwealth System Of Higher Education IRAP gene as treatment for arthritis
EP0575545B1 (en) * 1991-03-15 2003-05-21 Amgen Inc. Pegylation of polypeptides
DK0639079T3 (da) * 1992-04-30 2000-06-13 Amgen Inc Fremgangsmåder til behandling af interleukin-1- og tumornekrosefaktor-medierede sygdomme
WO1994006457A1 (en) * 1992-09-17 1994-03-31 Synergen, Inc. Pharmaceutical formulations of interleukin-1 inhibitors
US5780021A (en) * 1993-03-05 1998-07-14 Georgetown University Method for treating type 1 diabetes using α-interferon and/or β-i
EP0701563A4 (en) * 1993-03-08 1997-07-02 Univ Pittsburgh GENE TRANSFER FOR THE TREATMENT OF CONNECTIVE TISSUES IN A HOST MAMMAL
ATE226828T1 (de) * 1993-03-19 2002-11-15 Vacsyn Sa Zusammensetzungen für die anwendung in menschlicher therapie, charakterisiert durch die assoziation eines muramylpeptids mit einem cytokin
US6326353B1 (en) * 1993-03-23 2001-12-04 Sequus Pharmaceuticals, Inc. Enhanced circulation effector composition and method
FR2706772A1 (en) * 1993-06-22 1994-12-30 Vacsyn Sa Prevention and treatment of septic syndrome with an immunosuppressant, in particular cyclosporin.
WO1995021629A1 (en) * 1994-02-08 1995-08-17 Amgen Inc. Oral delivery of chemically modified proteins

Also Published As

Publication number Publication date
HUP0002755A2 (hu) 2000-12-28
ES2267188T3 (es) 2007-03-01
CY1107314T1 (el) 2012-11-21
TW474817B (en) 2002-02-01
JP2001515047A (ja) 2001-09-18
CN1267225A (zh) 2000-09-20
WO1999008702A1 (en) 1999-02-25
US6013253A (en) 2000-01-11
KR20010030563A (ko) 2001-04-16
HK1030157A1 (en) 2001-04-27
AU741074B2 (en) 2001-11-22
JP3813440B2 (ja) 2006-08-23
KR100415636B1 (ko) 2004-01-24
CA2299361A1 (en) 1999-02-25
EP1003546A1 (en) 2000-05-31
PT1003546E (pt) 2006-12-29
HUP0002755A3 (en) 2001-11-28
DE69835823T2 (de) 2007-08-09
AU8300698A (en) 1999-03-08
CN1183963C (zh) 2005-01-12
ATE338563T1 (de) 2006-09-15
EP1003546B1 (en) 2006-09-06
CA2299361C (en) 2009-09-29
IL134345A0 (en) 2001-04-30
DE69835823D1 (de) 2006-10-19
HU229045B1 (en) 2013-07-29
IL134345A (en) 2011-03-31

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