DK0996726T3 - T-celle-membranprotein (TIRC7), peptider og antistoffer afledt deraf og anvendelse deraf - Google Patents
T-celle-membranprotein (TIRC7), peptider og antistoffer afledt deraf og anvendelse derafInfo
- Publication number
- DK0996726T3 DK0996726T3 DK98945293T DK98945293T DK0996726T3 DK 0996726 T3 DK0996726 T3 DK 0996726T3 DK 98945293 T DK98945293 T DK 98945293T DK 98945293 T DK98945293 T DK 98945293T DK 0996726 T3 DK0996726 T3 DK 0996726T3
- Authority
- DK
- Denmark
- Prior art keywords
- peptides
- cell
- tirc7
- derived therefrom
- membrane protein
- Prior art date
Links
- 210000001744 T-lymphocyte Anatomy 0.000 title abstract 5
- 101000854875 Homo sapiens V-type proton ATPase 116 kDa subunit a 3 Proteins 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 102100020738 V-type proton ATPase 116 kDa subunit a 3 Human genes 0.000 title abstract 3
- 108010052285 Membrane Proteins Proteins 0.000 title 1
- 102000018697 Membrane Proteins Human genes 0.000 title 1
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000000172 allergic effect Effects 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000001363 autoimmune Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 108091005703 transmembrane proteins Proteins 0.000 abstract 1
- 102000035160 transmembrane proteins Human genes 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Transplantation (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19738710A DE19738710A1 (de) | 1997-08-29 | 1997-08-29 | Verwendung von TIRC7 zur Herstellung von Mitteln zur Inhibition der Immunantwort |
| DE29802653 | 1998-02-12 | ||
| PCT/EP1998/005462 WO1999011782A1 (en) | 1997-08-29 | 1998-08-28 | T-cell membrane protein (tirc7), peptides and antibodies derived therefrom and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0996726T3 true DK0996726T3 (da) | 2004-04-13 |
Family
ID=26039678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98945293T DK0996726T3 (da) | 1997-08-29 | 1998-08-28 | T-celle-membranprotein (TIRC7), peptider og antistoffer afledt deraf og anvendelse deraf |
Country Status (10)
| Country | Link |
|---|---|
| EP (2) | EP0996726B1 (enExample) |
| JP (1) | JP4459435B2 (enExample) |
| AT (1) | ATE256185T1 (enExample) |
| AU (1) | AU751151C (enExample) |
| CA (1) | CA2301499C (enExample) |
| DE (1) | DE69820449T2 (enExample) |
| DK (1) | DK0996726T3 (enExample) |
| ES (1) | ES2213295T3 (enExample) |
| PT (1) | PT996726E (enExample) |
| WO (1) | WO1999011782A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL134830A0 (en) * | 2000-03-01 | 2001-05-20 | Chay 13 Medical Res Group N V | Peptides and immunostimulatory and anti-bacterial pharmaceutical compositions containing them |
| AU2001263888A1 (en) * | 2000-05-03 | 2001-11-12 | Genpat77 Pharmacogenetics Ag | Uses of tgap7 for the modulation of leucocyte activation |
| US20040072780A1 (en) * | 2000-10-30 | 2004-04-15 | Nalan Utku | Methods for obtaining inhibitors of tirc7 ligand binding and uses thereof |
| US6905827B2 (en) | 2001-06-08 | 2005-06-14 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases |
| US7026121B1 (en) | 2001-06-08 | 2006-04-11 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
| US20050048067A1 (en) * | 2001-09-17 | 2005-03-03 | Nalan Utku | Peptides capable of modulating immune response |
| EP1448227A2 (en) * | 2001-11-27 | 2004-08-25 | GenPat77 Pharmacogenetics AG | Use of t-cell immune response cdna 7 (tirc7) for modulation of angiogenesis and/or neovascularization |
| EP1492817A2 (en) * | 2001-12-21 | 2005-01-05 | GenPat77 Pharmacogenetics AG | Therapeutic monoclonal anti-tirc7 antibodies for use in immune related and other diseases |
| JP2005531282A (ja) | 2001-12-21 | 2005-10-20 | ゲンパト７７ ファーマコジェネティクス エージー | 炎症性疾患の治療に用いる抗ｔｉｒｃ７抗体 |
| EP1492555A2 (en) * | 2002-02-04 | 2005-01-05 | Nalan Utku | Compositions and methods for modulation of effects on phagocyte and lymphoid cell population |
| US20050221424A1 (en) * | 2002-04-26 | 2005-10-06 | Nalan Utku | Bispecific molecules for use in therapy and diagnosis of immune related and other diseases |
| WO2003093318A1 (en) * | 2002-04-29 | 2003-11-13 | Genpat77 Pharmacogenetics Ag | Novel antibody binding tcr and tirc7 and its use in therapy and diagnosis |
| CN101268373A (zh) * | 2005-05-17 | 2008-09-17 | 塞尔艾克特制药有限公司 | 作为检测早期免疫激活的标记物的tirc7 |
| WO2006122792A1 (en) * | 2005-05-17 | 2006-11-23 | Genpat77 Pharmacogenetics Ag | Peptides capable of modulating the function of tirc7 |
| DE202011103324U1 (de) | 2011-07-12 | 2012-01-02 | Nekonal S.A.R.L. | Therapeutische anti-TIRC7 Antikörper für die Verwendung in Immun und anderen Krankheiten |
| CA3033645A1 (en) | 2016-08-09 | 2018-02-15 | Nekonal S.A.R.L. | Tirc7 based diagnostic and therapy of cancer |
| CA3033620A1 (en) | 2016-08-10 | 2018-02-15 | Nekonal S.A.R.L. | Tirc7 based diagnostic and therapy of solid cancer |
| US20220288120A1 (en) | 2019-08-14 | 2022-09-15 | Nekonal S.A.R.L. | Method for producing engineered tirc7 specific t-regulatory cells (tregs) |
-
1998
- 1998-08-28 EP EP98945293A patent/EP0996726B1/en not_active Expired - Lifetime
- 1998-08-28 PT PT98945293T patent/PT996726E/pt unknown
- 1998-08-28 DE DE69820449T patent/DE69820449T2/de not_active Expired - Lifetime
- 1998-08-28 EP EP03015210A patent/EP1350848A3/en not_active Withdrawn
- 1998-08-28 DK DK98945293T patent/DK0996726T3/da active
- 1998-08-28 CA CA2301499A patent/CA2301499C/en not_active Expired - Fee Related
- 1998-08-28 AU AU92654/98A patent/AU751151C/en not_active Ceased
- 1998-08-28 AT AT98945293T patent/ATE256185T1/de active
- 1998-08-28 WO PCT/EP1998/005462 patent/WO1999011782A1/en not_active Ceased
- 1998-08-28 ES ES98945293T patent/ES2213295T3/es not_active Expired - Lifetime
- 1998-08-28 JP JP2000508792A patent/JP4459435B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2213295T3 (es) | 2004-08-16 |
| CA2301499C (en) | 2010-01-26 |
| WO1999011782A1 (en) | 1999-03-11 |
| EP1350848A3 (en) | 2004-02-04 |
| ATE256185T1 (de) | 2003-12-15 |
| EP0996726B1 (en) | 2003-12-10 |
| EP1350848A2 (en) | 2003-10-08 |
| PT996726E (pt) | 2004-04-30 |
| EP0996726A1 (en) | 2000-05-03 |
| AU751151C (en) | 2006-09-14 |
| DE69820449T2 (de) | 2005-03-10 |
| JP2001514852A (ja) | 2001-09-18 |
| JP4459435B2 (ja) | 2010-04-28 |
| AU751151B2 (en) | 2002-08-08 |
| CA2301499A1 (en) | 1999-03-11 |
| DE69820449D1 (de) | 2004-01-22 |
| AU9265498A (en) | 1999-03-22 |
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