DK0991640T3 - Syntese af mellemprodukter, der er anvendelige til fremstilling af bromsubstituerede tricykliske forbindelser - Google Patents

Syntese af mellemprodukter, der er anvendelige til fremstilling af bromsubstituerede tricykliske forbindelser

Info

Publication number
DK0991640T3
DK0991640T3 DK98928873T DK98928873T DK0991640T3 DK 0991640 T3 DK0991640 T3 DK 0991640T3 DK 98928873 T DK98928873 T DK 98928873T DK 98928873 T DK98928873 T DK 98928873T DK 0991640 T3 DK0991640 T3 DK 0991640T3
Authority
DK
Denmark
Prior art keywords
brake
synthesis
preparation
intermediates useful
tricyclic compounds
Prior art date
Application number
DK98928873T
Other languages
Danish (da)
English (en)
Inventor
Xing Chen
Yee-Shing Wong
Guang-Zhong Wu
Marc Poirier
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DK0991640T3 publication Critical patent/DK0991640T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
DK98928873T 1997-06-16 1998-06-15 Syntese af mellemprodukter, der er anvendelige til fremstilling af bromsubstituerede tricykliske forbindelser DK0991640T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/882,753 US5760232A (en) 1997-06-16 1997-06-16 Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds
PCT/US1998/011403 WO1998057958A1 (en) 1997-06-16 1998-06-15 Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds

Publications (1)

Publication Number Publication Date
DK0991640T3 true DK0991640T3 (da) 2002-05-27

Family

ID=25381267

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98928873T DK0991640T3 (da) 1997-06-16 1998-06-15 Syntese af mellemprodukter, der er anvendelige til fremstilling af bromsubstituerede tricykliske forbindelser

Country Status (15)

Country Link
US (1) US5760232A (es)
EP (1) EP0991640B1 (es)
JP (1) JP3210023B2 (es)
AR (1) AR015886A1 (es)
AT (1) ATE214062T1 (es)
AU (1) AU8056898A (es)
CA (1) CA2293709C (es)
DE (1) DE69804100T2 (es)
DK (1) DK0991640T3 (es)
ES (1) ES2169917T3 (es)
IN (1) IN187755B (es)
MY (1) MY133531A (es)
PT (1) PT991640E (es)
WO (1) WO1998057958A1 (es)
ZA (1) ZA985207B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998620A (en) * 1997-03-25 1999-12-07 Schering Corporation Synthesis of intermediates useful in preparing tricyclic compounds
PT1556358E (pt) * 2002-10-03 2007-09-25 Schering Corp ''alquilação enantiosselectiva de compostos tricíclicos''
US9012450B2 (en) 2011-12-28 2015-04-21 Global Blood Therapeutics, Inc. Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
SI2797416T1 (sl) 2011-12-28 2017-12-29 Global Blood Therapeutics, Inc. Substituirane spojine benzaldehida in metode njihove uporabe pri povečanju oksigenacije tkiva
BR112015021982B1 (pt) 2013-03-15 2022-12-13 Global Blood Therapeutics, Inc Compostos e seus usos para a modulação de hemoglobina
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
WO2014145040A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
AP2015008721A0 (en) 2013-03-15 2015-09-30 Global Blood Therapeutics Inc Compounds and uses thereof for the modulation of hemoglobin
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
EP2968299B1 (en) 2013-03-15 2021-01-20 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US20140274961A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
EA202092627A1 (ru) 2013-11-18 2021-09-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
CN114181195A (zh) 2014-02-07 2022-03-15 全球血液疗法股份有限公司 一种化合物的结晶多晶型物
MA41841A (fr) 2015-03-30 2018-02-06 Global Blood Therapeutics Inc Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
SG11201804647TA (en) 2015-12-04 2018-06-28 Global Blood Therapeutics Inc Dosing regimens for 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
TWI752307B (zh) 2016-05-12 2022-01-11 美商全球血液治療公司 新穎化合物及製造化合物之方法
TW202332423A (zh) 2016-10-12 2023-08-16 美商全球血液治療公司 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
US11014884B2 (en) 2018-10-01 2021-05-25 Global Blood Therapeutics, Inc. Modulators of hemoglobin
CN112341433A (zh) * 2020-11-16 2021-02-09 成都大学 一种氯雷他定的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089496A (en) * 1986-10-31 1992-02-18 Schering Corporation Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies
TW308594B (es) * 1993-10-15 1997-06-21 Schering Corp
IL111235A (en) * 1993-10-15 2001-03-19 Schering Plough Corp Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
TW350844B (en) * 1995-12-22 1999-01-21 Schering Corp Tricyclic amides useful to inhibition of G-protein function and for treatment of proliferative diseases

Also Published As

Publication number Publication date
EP0991640B1 (en) 2002-03-06
DE69804100D1 (de) 2002-04-11
AU8056898A (en) 1999-01-04
US5760232A (en) 1998-06-02
ES2169917T3 (es) 2002-07-16
CA2293709A1 (en) 1998-12-23
EP0991640A1 (en) 2000-04-12
CA2293709C (en) 2004-02-10
AR015886A1 (es) 2001-05-30
MY133531A (en) 2007-11-30
JP3210023B2 (ja) 2001-09-17
ZA985207B (en) 1999-04-07
PT991640E (pt) 2002-07-31
WO1998057958A1 (en) 1998-12-23
IN187755B (es) 2002-06-15
JP2000513032A (ja) 2000-10-03
ATE214062T1 (de) 2002-03-15
DE69804100T2 (de) 2002-10-31

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