DK0986580T3 - Oligosaccharidblandinger med antitrombotisk aktivitet - Google Patents

Oligosaccharidblandinger med antitrombotisk aktivitet

Info

Publication number
DK0986580T3
DK0986580T3 DK98929355T DK98929355T DK0986580T3 DK 0986580 T3 DK0986580 T3 DK 0986580T3 DK 98929355 T DK98929355 T DK 98929355T DK 98929355 T DK98929355 T DK 98929355T DK 0986580 T3 DK0986580 T3 DK 0986580T3
Authority
DK
Denmark
Prior art keywords
mixture
weight
content
sulphate
disaccharide
Prior art date
Application number
DK98929355T
Other languages
English (en)
Inventor
Mons Lundqvist
Kristian Betton Johansen
Original Assignee
Leo Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10813494&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0986580(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Leo Pharma As filed Critical Leo Pharma As
Application granted granted Critical
Publication of DK0986580T3 publication Critical patent/DK0986580T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
DK98929355T 1997-06-03 1998-05-15 Oligosaccharidblandinger med antitrombotisk aktivitet DK0986580T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9711443.3A GB9711443D0 (en) 1997-06-03 1997-06-03 Chemical suppositions
PCT/EP1998/003007 WO1998055514A1 (en) 1997-06-03 1998-05-15 Oligosaccharide mixtures having antithrombotic activity

Publications (1)

Publication Number Publication Date
DK0986580T3 true DK0986580T3 (da) 2003-08-04

Family

ID=10813494

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98929355T DK0986580T3 (da) 1997-06-03 1998-05-15 Oligosaccharidblandinger med antitrombotisk aktivitet

Country Status (20)

Country Link
US (1) US6486137B1 (da)
EP (1) EP0986580B1 (da)
JP (1) JP2002502454A (da)
KR (1) KR20010013284A (da)
CN (1) CN1145643C (da)
AT (1) ATE236933T1 (da)
AU (1) AU740671B2 (da)
CA (1) CA2293587A1 (da)
CZ (1) CZ292622B6 (da)
DE (1) DE69813216T2 (da)
DK (1) DK0986580T3 (da)
ES (1) ES2193534T3 (da)
GB (1) GB9711443D0 (da)
HK (1) HK1028251A1 (da)
HU (1) HUP0002333A3 (da)
NZ (1) NZ501254A (da)
PL (1) PL337231A1 (da)
PT (1) PT986580E (da)
RU (1) RU2216548C2 (da)
WO (1) WO1998055514A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998014169A1 (en) 1996-09-30 1998-04-09 Brigham & Women's Hospital Methods and compounds for treatment of abnormal uterine bleeding
EP1423130A1 (en) * 2001-08-28 2004-06-02 Leo Pharma A/S Antithrombotic compositions comprising low molecular weight heparin and low molecular weight dermatan sulphate
US20040171819A1 (en) 2002-10-10 2004-09-02 Aventis Pharma S.A. Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
CN100345868C (zh) * 2003-04-18 2007-10-31 山东大学 一种低分子硫酸皮肤素及其制备方法
WO2005092931A1 (en) * 2004-03-26 2005-10-06 Taisho Pharmaceutical Co., Ltd. Preparation process of oligoglycosaminoglycan, and reducing end glucuronic acid type oligochondroitin sulfate and pharmaceutical composition comprising the same
US20050261241A1 (en) 2004-05-19 2005-11-24 Celsus Biopharmaceuticals, Inc. Use of dermatan sulfates and/or desulfated heparins to treat or prevent heparinoid-induced autoimmune responses
CN102046781A (zh) * 2008-05-30 2011-05-04 动量制药公司 糖结构以及制造和使用此类结构的方法
ES2364683B1 (es) * 2009-12-29 2012-08-08 Bioibérica S.A. Disacáridos sulfatados para el tratamiento de enfermedades neurodegenerativas y/o neurovasculares.
WO2013006906A1 (en) * 2011-07-11 2013-01-17 Commonwealth Scientific And Industrial Research Organisation Dermatan sulphate, pharmaceutical compositions and process for producing same
WO2013095215A1 (en) 2011-12-19 2013-06-27 Dilaforette Ab Low anticoagulant heparins
DK2794665T3 (da) 2011-12-19 2018-01-29 Dilafor Ab Ikke-antikoagulative glycosaminoglycaner omfattende disaccharid-gentagelsesenhed og medicinsk anvendelse deraf
CN103160486A (zh) * 2013-04-02 2013-06-19 黑龙江迪龙制药有限公司 一种猪凝血酶的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1230582B (it) * 1988-10-21 1991-10-28 Opocrin S P A Lab Farmabiologi Oliogosaccaridi di dermatan solfato ed eparina aventi attivita' antiaterosclerotica
IT1251182B (it) * 1991-08-28 1995-05-04 Opocrin Spa Oligosaccaridi di dermatan solfato, processo per la loro produzione e relative composizioni farmaceutiche.
IT1251183B (it) * 1991-08-28 1995-05-04 Opocrin Spa Dermatan solfato ad alto titolo, dotato di elevata attivita' trombolitica, e forme farmaceutiche che lo contengono.
US5922690A (en) * 1996-04-25 1999-07-13 Van Gorp; Cornelius L. Dermatan disulfate, an inhibitor of thrombin generation and activation

Also Published As

Publication number Publication date
DE69813216T2 (de) 2004-01-29
EP0986580B1 (en) 2003-04-09
EP0986580A1 (en) 2000-03-22
CN1145643C (zh) 2004-04-14
CA2293587A1 (en) 1998-12-10
DE69813216D1 (de) 2003-05-15
CN1259143A (zh) 2000-07-05
PT986580E (pt) 2003-08-29
WO1998055514A1 (en) 1998-12-10
AU7914698A (en) 1998-12-21
ES2193534T3 (es) 2003-11-01
HUP0002333A2 (hu) 2000-12-28
KR20010013284A (ko) 2001-02-26
NZ501254A (en) 2001-12-21
GB9711443D0 (en) 1997-07-30
HUP0002333A3 (en) 2002-01-28
AU740671B2 (en) 2001-11-08
ATE236933T1 (de) 2003-04-15
US6486137B1 (en) 2002-11-26
RU2216548C2 (ru) 2003-11-20
JP2002502454A (ja) 2002-01-22
CZ292622B6 (cs) 2003-11-12
CZ431699A3 (cs) 2000-04-12
HK1028251A1 (en) 2001-02-09
PL337231A1 (en) 2000-08-14

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