DK0983271T3 - Carbocyklisk nucleosidhemisulfat og anvendelsen deraf i behandlingen af virusinfektioner - Google Patents

Carbocyklisk nucleosidhemisulfat og anvendelsen deraf i behandlingen af virusinfektioner

Info

Publication number
DK0983271T3
DK0983271T3 DK98925601T DK98925601T DK0983271T3 DK 0983271 T3 DK0983271 T3 DK 0983271T3 DK 98925601 T DK98925601 T DK 98925601T DK 98925601 T DK98925601 T DK 98925601T DK 0983271 T3 DK0983271 T3 DK 0983271T3
Authority
DK
Denmark
Prior art keywords
treatment
viral infections
carbocyclic nucleoside
hemisulfate
nucleoside hemisulfate
Prior art date
Application number
DK98925601T
Other languages
Danish (da)
English (en)
Inventor
Alastair Couper Brodie
Martin Francis Jones
John Frederick Seager
Christopher John Wallis
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10812407&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0983271(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DK0983271T3 publication Critical patent/DK0983271T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Seasonings (AREA)
DK98925601T 1997-05-17 1998-05-14 Carbocyklisk nucleosidhemisulfat og anvendelsen deraf i behandlingen af virusinfektioner DK0983271T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9709945.1A GB9709945D0 (en) 1997-05-17 1997-05-17 A novel salt
PCT/EP1998/002835 WO1998052949A1 (en) 1997-05-17 1998-05-14 Carbocyclic nucleoside hemisulfate and its use in treating viral infections

Publications (1)

Publication Number Publication Date
DK0983271T3 true DK0983271T3 (da) 2004-05-10

Family

ID=10812407

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98925601T DK0983271T3 (da) 1997-05-17 1998-05-14 Carbocyklisk nucleosidhemisulfat og anvendelsen deraf i behandlingen af virusinfektioner

Country Status (51)

Country Link
US (1) US6294540B1 (uk)
EP (1) EP0983271B1 (uk)
JP (2) JP3150711B2 (uk)
KR (1) KR100521292B1 (uk)
CN (2) CN100408580C (uk)
AP (1) AP2009A (uk)
AR (2) AR015668A1 (uk)
AT (1) ATE259811T1 (uk)
AU (1) AU739953B2 (uk)
BG (1) BG64390B1 (uk)
BR (1) BRPI9809126B8 (uk)
CA (1) CA2289753C (uk)
CO (1) CO4940435A1 (uk)
DE (1) DE69821758T2 (uk)
DK (1) DK0983271T3 (uk)
DZ (1) DZ2493A1 (uk)
EA (1) EA001809B1 (uk)
EE (1) EE03924B1 (uk)
EG (1) EG23836A (uk)
ES (1) ES2214712T3 (uk)
GB (3) GB9709945D0 (uk)
GE (1) GEP20022680B (uk)
HK (1) HK1024236A1 (uk)
HN (1) HN1998000071A (uk)
HR (1) HRP980265B1 (uk)
HU (1) HU226563B1 (uk)
ID (1) ID24910A (uk)
IL (2) IL132793A0 (uk)
IS (1) IS2207B (uk)
JO (1) JO2032B1 (uk)
MA (1) MA26498A1 (uk)
MY (1) MY120151A (uk)
NO (1) NO324731B1 (uk)
NZ (2) NZ500865A (uk)
OA (1) OA11304A (uk)
PA (1) PA8451301A1 (uk)
PE (1) PE78799A1 (uk)
PL (1) PL189527B1 (uk)
PT (1) PT983271E (uk)
RS (1) RS49655B (uk)
SA (1) SA98190179B1 (uk)
SI (1) SI0983271T1 (uk)
SK (1) SK285159B6 (uk)
SV (1) SV1998000057A (uk)
TN (1) TNSN98065A1 (uk)
TR (1) TR199902810T2 (uk)
TW (1) TW480259B (uk)
UA (1) UA56231C2 (uk)
UY (1) UY25004A1 (uk)
WO (1) WO1998052949A1 (uk)
ZA (2) ZA984083B (uk)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9802472D0 (en) 1998-02-06 1998-04-01 Glaxo Group Ltd Pharmaceutical compositions
HU226998B1 (en) * 2000-11-23 2010-04-28 Richter Gedeon Nyrt Desloratadine hemisulphate, process for the preparation thereof and pharmaceutical compositions containing the same
GB0320738D0 (en) 2003-09-04 2003-10-08 Glaxo Group Ltd Novel process
MX2009002446A (es) * 2006-09-28 2009-03-20 Esteve Quimica Sa Procedimiento para la preparacion de abacavir.
EP1905772A1 (en) * 2006-09-28 2008-04-02 Esteve Quimica, S.A. Process for the preparation of abacavir
EP2085397A1 (en) 2008-01-21 2009-08-05 Esteve Quimica, S.A. Crystalline form of abacavir
EP2218721A1 (en) * 2009-02-11 2010-08-18 LEK Pharmaceuticals d.d. Novel salts of sitagliptin
EP2305680A3 (en) 2009-09-30 2011-05-18 Aurobindo Pharma Limited Novel salts of (1S,4R)-cis-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol
PT2531027E (pt) 2010-01-27 2015-09-16 Viiv Healthcare Co Combinação terapêutica compreendendo dolutegravir, abacavir e lamivudina
EP2697238B1 (en) 2011-04-08 2019-03-20 Laurus Labs Limited Solid forms of antiretroviral compounds, process for the preparation and their pharmaceutical composition thereof
WO2014133085A1 (ja) 2013-02-27 2014-09-04 国立大学法人京都大学 がんの予防または治療用医薬組成物
CN104788451A (zh) * 2014-01-21 2015-07-22 浙江九洲药业股份有限公司 一种阿巴卡韦的制备方法
CN105315280A (zh) * 2014-06-06 2016-02-10 上海迪赛诺化学制药有限公司 一种阿巴卡韦结晶体及其制备方法
US10874687B1 (en) 2020-02-27 2020-12-29 Atea Pharmaceuticals, Inc. Highly active compounds against COVID-19

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
GB9417249D0 (en) * 1994-08-26 1994-10-19 Wellcome Found A novel salt
MY115461A (en) * 1995-03-30 2003-06-30 Wellcome Found Synergistic combinations of zidovudine, 1592u89 and 3tc
KR20000022225A (ko) * 1996-06-25 2000-04-25 그레이엄 브레레톤;레슬리 에드워즈 Hiv 치료에 사용하기 위한 vx478, 지도부딘 및(또는)1592u89를 포함하는 배합물

Also Published As

Publication number Publication date
BRPI9809126B8 (pt) 2021-07-06
EG23836A (en) 2007-10-02
SA98190179B1 (ar) 2006-08-15
IS2207B (is) 2007-02-15
TNSN98065A1 (fr) 2005-03-15
HU226563B1 (en) 2009-04-28
GEP20022680B (en) 2002-04-25
RS49655B (sr) 2007-09-21
DZ2493A1 (fr) 2004-06-20
OA11304A (en) 2003-10-22
JP2000327679A (ja) 2000-11-28
IS5246A (is) 1999-11-11
US6294540B1 (en) 2001-09-25
PE78799A1 (es) 1999-08-31
AU739953B2 (en) 2001-10-25
HRP980265A2 (en) 1999-02-28
GB2348202A (en) 2000-09-27
CN1150194C (zh) 2004-05-19
MA26498A1 (fr) 2004-12-20
NO995622L (no) 2000-01-14
BRPI9809126B1 (pt) 2018-02-06
JO2032B1 (en) 1999-05-15
ES2214712T3 (es) 2004-09-16
EE9900537A (et) 2000-06-15
PA8451301A1 (es) 2000-05-24
NZ500865A (en) 2001-04-27
NZ510622A (en) 2002-04-26
KR100521292B1 (ko) 2005-10-17
SI0983271T1 (en) 2004-06-30
CN100408580C (zh) 2008-08-06
SK285159B6 (sk) 2006-07-07
CA2289753A1 (en) 1998-11-26
GB2340491B (en) 2000-10-18
PL189527B1 (pl) 2005-08-31
EP0983271B1 (en) 2004-02-18
IL132793A0 (en) 2001-03-19
MY120151A (en) 2005-09-30
GB2348202B (en) 2001-08-08
AU7765598A (en) 1998-12-11
DE69821758T2 (de) 2005-01-13
AP9901688A0 (en) 1999-12-31
JP2000514096A (ja) 2000-10-24
CO4940435A1 (es) 2000-07-24
EA199900944A1 (ru) 2000-06-26
DE69821758D1 (de) 2004-03-25
UA56231C2 (uk) 2003-05-15
WO1998052949A1 (en) 1998-11-26
AP2009A (en) 2009-06-26
NO995622D0 (no) 1999-11-16
GB0010222D0 (en) 2000-06-14
YU59599A (uk) 2002-08-12
UY25004A1 (es) 2000-10-31
GB2340491A (en) 2000-02-23
AR059120A2 (es) 2008-03-12
AR015668A1 (es) 2001-05-16
EE03924B1 (et) 2002-12-16
HK1024236A1 (en) 2000-10-05
GB9926839D0 (en) 2000-01-12
ATE259811T1 (de) 2004-03-15
ZA984083B (en) 1999-11-15
CN1515572A (zh) 2004-07-28
HRP980265B1 (en) 2004-10-31
KR20010012623A (ko) 2001-02-26
HUP0002754A2 (hu) 2001-06-28
TR199902810T2 (xx) 2000-02-21
ZA984085B (en) 2000-01-26
BG103959A (en) 2000-12-29
GB9709945D0 (en) 1997-07-09
HUP0002754A3 (en) 2003-01-28
SK156199A3 (en) 2000-07-11
BG64390B1 (bg) 2004-12-30
TW480259B (en) 2002-03-21
SV1998000057A (es) 1999-03-02
BR9809126A (pt) 2000-08-01
IL132793A (en) 2006-10-31
CN1263529A (zh) 2000-08-16
CA2289753C (en) 2007-01-23
NO324731B1 (no) 2007-12-03
ID24910A (id) 2000-08-31
EP0983271A1 (en) 2000-03-08
HN1998000071A (es) 1999-03-19
PL336888A1 (en) 2000-07-17
PT983271E (pt) 2004-07-30
EA001809B1 (ru) 2001-08-27
JP3150711B2 (ja) 2001-03-26

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