DK0979822T3 - Fremgangsmåde til fremstilling af 2-carbamoyl-pyridiner - Google Patents

Fremgangsmåde til fremstilling af 2-carbamoyl-pyridiner

Info

Publication number
DK0979822T3
DK0979822T3 DK99114893T DK99114893T DK0979822T3 DK 0979822 T3 DK0979822 T3 DK 0979822T3 DK 99114893 T DK99114893 T DK 99114893T DK 99114893 T DK99114893 T DK 99114893T DK 0979822 T3 DK0979822 T3 DK 0979822T3
Authority
DK
Denmark
Prior art keywords
preparation
pyridines
carbamoyl
carbamoylation
concerned
Prior art date
Application number
DK99114893T
Other languages
Danish (da)
English (en)
Inventor
Uwe Klinkhammer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0979822T3 publication Critical patent/DK0979822T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
DK99114893T 1998-08-10 1999-07-30 Fremgangsmåde til fremstilling af 2-carbamoyl-pyridiner DK0979822T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98114978 1998-08-10

Publications (1)

Publication Number Publication Date
DK0979822T3 true DK0979822T3 (da) 2006-03-27

Family

ID=8232437

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99114893T DK0979822T3 (da) 1998-08-10 1999-07-30 Fremgangsmåde til fremstilling af 2-carbamoyl-pyridiner

Country Status (10)

Country Link
US (1) US6103902A (es)
EP (1) EP0979822B1 (es)
JP (1) JP3344972B2 (es)
KR (1) KR100362081B1 (es)
CN (1) CN1117746C (es)
AT (1) ATE311382T1 (es)
CA (1) CA2279796C (es)
DE (1) DE69928610T2 (es)
DK (1) DK0979822T3 (es)
ES (1) ES2252894T3 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6670362B2 (en) 2000-09-20 2003-12-30 Pfizer Inc. Pyridazine endothelin antagonists
CN105669542A (zh) * 2016-03-08 2016-06-15 南京师范大学 一种直接催化氧化法合成吡啶伯酰胺化合物的方法
CN116456984A (zh) 2020-11-05 2023-07-18 爱杜西亚药品有限公司 克拉生坦二钠盐的稳定结晶水合物
AU2022416870A1 (en) 2021-12-17 2024-06-27 Nxera Pharma Co., Ltd. Clazosentan disodium salt, its preparation and pharmaceutical compositions comprising the same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW313568B (es) * 1994-12-20 1997-08-21 Hoffmann La Roche

Also Published As

Publication number Publication date
CA2279796A1 (en) 2000-02-10
KR100362081B1 (ko) 2002-11-23
US6103902A (en) 2000-08-15
DE69928610D1 (de) 2006-01-05
CN1245803A (zh) 2000-03-01
CN1117746C (zh) 2003-08-13
CA2279796C (en) 2003-09-30
JP2000063377A (ja) 2000-02-29
KR20000017194A (ko) 2000-03-25
ES2252894T3 (es) 2006-05-16
EP0979822B1 (en) 2005-11-30
DE69928610T2 (de) 2006-08-10
EP0979822A1 (en) 2000-02-16
ATE311382T1 (de) 2005-12-15
JP3344972B2 (ja) 2002-11-18

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