DK0975638T3 - Sidekædemodificerede epothiloner - Google Patents

Sidekædemodificerede epothiloner

Info

Publication number
DK0975638T3
DK0975638T3 DK98912388T DK98912388T DK0975638T3 DK 0975638 T3 DK0975638 T3 DK 0975638T3 DK 98912388 T DK98912388 T DK 98912388T DK 98912388 T DK98912388 T DK 98912388T DK 0975638 T3 DK0975638 T3 DK 0975638T3
Authority
DK
Denmark
Prior art keywords
chain modified
modified epothilones
epothilones
chain
modified
Prior art date
Application number
DK98912388T
Other languages
Danish (da)
English (en)
Inventor
Gerhard Hoefle
Michael Sefkow
Original Assignee
Biotechnolog Forschung Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotechnolog Forschung Gmbh filed Critical Biotechnolog Forschung Gmbh
Application granted granted Critical
Publication of DK0975638T3 publication Critical patent/DK0975638T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
DK98912388T 1997-02-25 1998-02-25 Sidekædemodificerede epothiloner DK0975638T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19707505 1997-02-25
PCT/EP1998/001060 WO1998038192A1 (de) 1997-02-25 1998-02-25 Seitenkettenmodifizierte epothilone

Publications (1)

Publication Number Publication Date
DK0975638T3 true DK0975638T3 (da) 2002-11-18

Family

ID=7821415

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98912388T DK0975638T3 (da) 1997-02-25 1998-02-25 Sidekædemodificerede epothiloner

Country Status (25)

Country Link
US (1) US6359140B1 (pt)
EP (2) EP1201666A3 (pt)
JP (1) JP2001513098A (pt)
KR (1) KR100494179B1 (pt)
CN (2) CN1544436A (pt)
AR (1) AR011878A1 (pt)
AT (1) ATE221888T1 (pt)
AU (1) AU736062B2 (pt)
BR (1) BR9807742B1 (pt)
CA (1) CA2281105A1 (pt)
CZ (1) CZ298027B6 (pt)
DE (2) DE19880193D2 (pt)
DK (1) DK0975638T3 (pt)
ES (1) ES2183338T3 (pt)
HK (1) HK1023774A1 (pt)
HU (1) HU228851B1 (pt)
IL (1) IL131343A (pt)
NO (1) NO327211B1 (pt)
NZ (1) NZ337195A (pt)
PL (1) PL190422B1 (pt)
PT (1) PT975638E (pt)
RU (1) RU2201932C2 (pt)
TW (1) TW480263B (pt)
WO (1) WO1998038192A1 (pt)
ZA (1) ZA981575B (pt)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
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EP1367057B1 (de) * 1996-11-18 2008-09-17 Gesellschaft für biotechnologische Forschung mbH (GBF) Epothilone E und F
US20050043376A1 (en) * 1996-12-03 2005-02-24 Danishefsky Samuel J. Synthesis of epothilones, intermediates thereto, analogues and uses thereof
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US6660758B1 (en) 1996-12-13 2003-12-09 The Scripps Research Institute Epothilone analogs
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US7125875B2 (en) 1999-04-15 2006-10-24 Bristol-Myers Squibb Company Cyclic protein tyrosine kinase inhibitors
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US6593115B2 (en) 2000-03-24 2003-07-15 Bristol-Myers Squibb Co. Preparation of epothilone intermediates
US6589968B2 (en) * 2001-02-13 2003-07-08 Kosan Biosciences, Inc. Epothilone compounds and methods for making and using the same
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ATE389401T1 (de) 2001-01-25 2008-04-15 Bristol Myers Squibb Co Verfahren zur herstellung von pharmazeutischen zusammensetzungen enthaltend epothilon-analoga zur krebsbehandlung
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US6921769B2 (en) 2002-08-23 2005-07-26 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
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EP1567487A4 (en) 2002-11-15 2005-11-16 Bristol Myers Squibb Co OPEN-CHAINED, PROLYL-FROSTED MODULATORS OF ANDROGEN RECEPTOR FUNCTION
US7820702B2 (en) 2004-02-04 2010-10-26 Bristol-Myers Squibb Company Sulfonylpyrrolidine modulators of androgen receptor function and method
US7378426B2 (en) 2004-03-01 2008-05-27 Bristol-Myers Squibb Company Fused heterotricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3
US7696241B2 (en) 2004-03-04 2010-04-13 Bristol-Myers Squibb Company Bicyclic compounds as modulators of androgen receptor function and method
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CA2588400A1 (en) * 2004-11-18 2006-05-26 Bristol-Myers Squibb Company Enteric coated bead comprising ixabepilone, and preparation thereof
JP4954983B2 (ja) 2005-05-18 2012-06-20 ファーマサイエンス・インコーポレイテッド Birドメイン結合化合物
CN101535300B (zh) 2006-05-16 2014-05-28 埃格拉医疗公司 Iap bir域结合化合物
BRPI0718360A2 (pt) 2006-12-04 2013-11-12 Univ Illinois "composições e métodos para o tratamento do câncer com cupredoxinas e dna rico em cpg"
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Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4138042C2 (de) * 1991-11-19 1993-10-14 Biotechnolog Forschung Gmbh Epothilone, deren Herstellungsverfahren sowie diese Verbindungen enthaltende Mittel
WO1997019086A1 (de) * 1995-11-17 1997-05-29 GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) Epothilonderivate, herstellung und verwendung
US6441186B1 (en) * 1996-12-13 2002-08-27 The Scripps Research Institute Epothilone analogs
WO1998038192A1 (de) * 1997-02-25 1998-09-03 GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) Seitenkettenmodifizierte epothilone

Also Published As

Publication number Publication date
AR011878A1 (es) 2000-09-13
PT975638E (pt) 2002-12-31
HUP0002189A3 (en) 2001-12-28
DE19880193D2 (de) 2000-08-24
JP2001513098A (ja) 2001-08-28
AU6724998A (en) 1998-09-18
ZA981575B (en) 1998-09-08
EP0975638A1 (de) 2000-02-02
CA2281105A1 (en) 1998-09-03
DE59805110D1 (de) 2002-09-12
AU736062B2 (en) 2001-07-26
RU2201932C2 (ru) 2003-04-10
NO327211B1 (no) 2009-05-11
EP0975638B1 (de) 2002-08-07
ATE221888T1 (de) 2002-08-15
US6359140B1 (en) 2002-03-19
CZ286599A3 (cs) 2000-03-15
PL190422B1 (pl) 2005-12-30
CN1544436A (zh) 2004-11-10
KR100494179B1 (ko) 2005-06-10
NO994071D0 (no) 1999-08-24
KR20000075705A (ko) 2000-12-26
NO994071L (no) 1999-10-21
EP1201666A2 (de) 2002-05-02
TW480263B (en) 2002-03-21
HU228851B1 (en) 2013-06-28
EP1201666A3 (de) 2003-03-05
ES2183338T3 (es) 2003-03-16
WO1998038192A1 (de) 1998-09-03
PL335329A1 (en) 2000-04-25
BR9807742A (pt) 2000-02-22
CN1128803C (zh) 2003-11-26
IL131343A (en) 2004-03-28
BR9807742B1 (pt) 2010-12-14
HK1023774A1 (en) 2000-09-22
NZ337195A (en) 2001-05-25
CZ298027B6 (cs) 2007-05-30
CN1248974A (zh) 2000-03-29
IL131343A0 (en) 2001-01-28
HUP0002189A2 (hu) 2001-10-28

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