NO994071D0 - Epotilones med en modifisert sidekjede - Google Patents

Epotilones med en modifisert sidekjede

Info

Publication number
NO994071D0
NO994071D0 NO994071A NO994071A NO994071D0 NO 994071 D0 NO994071 D0 NO 994071D0 NO 994071 A NO994071 A NO 994071A NO 994071 A NO994071 A NO 994071A NO 994071 D0 NO994071 D0 NO 994071D0
Authority
NO
Norway
Prior art keywords
epotilones
side chain
modified side
modified
chain
Prior art date
Application number
NO994071A
Other languages
English (en)
Other versions
NO994071L (no
NO327211B1 (no
Inventor
Gerhard Hoefle
Michael Sefkow
Original Assignee
Biotechnolog Forschung Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotechnolog Forschung Gmbh filed Critical Biotechnolog Forschung Gmbh
Publication of NO994071D0 publication Critical patent/NO994071D0/no
Publication of NO994071L publication Critical patent/NO994071L/no
Publication of NO327211B1 publication Critical patent/NO327211B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Epoxy Compounds (AREA)
  • Silicon Polymers (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO19994071A 1997-02-25 1999-08-24 Epotiloner med en modifisert sidekjede, samt fremgangsmate for fremstilling derav NO327211B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19707505 1997-02-25
PCT/EP1998/001060 WO1998038192A1 (de) 1997-02-25 1998-02-25 Seitenkettenmodifizierte epothilone

Publications (3)

Publication Number Publication Date
NO994071D0 true NO994071D0 (no) 1999-08-24
NO994071L NO994071L (no) 1999-10-21
NO327211B1 NO327211B1 (no) 2009-05-11

Family

ID=7821415

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19994071A NO327211B1 (no) 1997-02-25 1999-08-24 Epotiloner med en modifisert sidekjede, samt fremgangsmate for fremstilling derav

Country Status (25)

Country Link
US (1) US6359140B1 (no)
EP (2) EP0975638B1 (no)
JP (1) JP2001513098A (no)
KR (1) KR100494179B1 (no)
CN (2) CN1544436A (no)
AR (1) AR011878A1 (no)
AT (1) ATE221888T1 (no)
AU (1) AU736062B2 (no)
BR (1) BR9807742B1 (no)
CA (1) CA2281105A1 (no)
CZ (1) CZ298027B6 (no)
DE (2) DE19880193D2 (no)
DK (1) DK0975638T3 (no)
ES (1) ES2183338T3 (no)
HK (1) HK1023774A1 (no)
HU (1) HU228851B1 (no)
IL (1) IL131343A (no)
NO (1) NO327211B1 (no)
NZ (1) NZ337195A (no)
PL (1) PL190422B1 (no)
PT (1) PT975638E (no)
RU (1) RU2201932C2 (no)
TW (1) TW480263B (no)
WO (1) WO1998038192A1 (no)
ZA (1) ZA981575B (no)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
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DE59712968D1 (de) 1996-11-18 2008-10-30 Biotechnolog Forschung Gmbh Epothilone E und F
US6867305B2 (en) 1996-12-03 2005-03-15 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
US6204388B1 (en) * 1996-12-03 2001-03-20 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
US20050043376A1 (en) * 1996-12-03 2005-02-24 Danishefsky Samuel J. Synthesis of epothilones, intermediates thereto, analogues and uses thereof
US6242469B1 (en) 1996-12-03 2001-06-05 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof
US6380394B1 (en) * 1996-12-13 2002-04-30 The Scripps Research Institute Epothilone analogs
US6441186B1 (en) * 1996-12-13 2002-08-27 The Scripps Research Institute Epothilone analogs
US6660758B1 (en) 1996-12-13 2003-12-09 The Scripps Research Institute Epothilone analogs
WO1998038192A1 (de) * 1997-02-25 1998-09-03 GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) Seitenkettenmodifizierte epothilone
US6605599B1 (en) 1997-07-08 2003-08-12 Bristol-Myers Squibb Company Epothilone derivatives
US6320045B1 (en) 1997-12-04 2001-11-20 Bristol-Myers Squibb Company Process for the reduction of oxiranyl epothilones to olefinic epothilones
US6365749B1 (en) 1997-12-04 2002-04-02 Bristol-Myers Squibb Company Process for the preparation of ring-opened epothilone intermediates which are useful for the preparation of epothilone analogs
US6683100B2 (en) 1999-01-19 2004-01-27 Novartis Ag Organic compounds
US6498257B1 (en) 1998-04-21 2002-12-24 Bristol-Myers Squibb Company 2,3-olefinic epothilone derivatives
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DE19907588A1 (de) * 1999-02-22 2000-08-24 Biotechnolog Forschung Gmbh C-21 Modifizierte Epothilone
US20020058286A1 (en) * 1999-02-24 2002-05-16 Danishefsky Samuel J. Synthesis of epothilones, intermediates thereto and analogues thereof
US6291684B1 (en) 1999-03-29 2001-09-18 Bristol-Myers Squibb Company Process for the preparation of aziridinyl epothilones from oxiranyl epothilones
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ES2391550T3 (es) 1999-04-15 2012-11-27 Bristol-Myers Squibb Company Inhibidores cíclicos de la proteína tirosina quinasa
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US7125893B1 (en) * 1999-04-30 2006-10-24 Schering Ag 6-alkenyl-, 6-alkinyl- and 6-epoxy-epothilone derivatives, process for their production, and their use in pharmaceutical preparations
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US6518421B1 (en) 2000-03-20 2003-02-11 Bristol-Myers Squibb Company Process for the preparation of epothilone analogs
US6593115B2 (en) 2000-03-24 2003-07-15 Bristol-Myers Squibb Co. Preparation of epothilone intermediates
US6589968B2 (en) * 2001-02-13 2003-07-08 Kosan Biosciences, Inc. Epothilone compounds and methods for making and using the same
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TW200400191A (en) 2002-05-15 2004-01-01 Bristol Myers Squibb Co Pharmaceutical compositions and methods of using C-21 modified epothilone derivatives
US7405234B2 (en) 2002-05-17 2008-07-29 Bristol-Myers Squibb Company Bicyclic modulators of androgen receptor function
WO2003105828A1 (en) 2002-06-14 2003-12-24 Bristol-Myers Squibb Company Combination of epothilone analogs and chemotherapeutic agents for the treatment of proliferative diseases
US7649006B2 (en) 2002-08-23 2010-01-19 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
US6921769B2 (en) 2002-08-23 2005-07-26 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
NZ538522A (en) 2002-08-23 2008-03-28 Sloan Kettering Inst Cancer Synthesis of epothilones, intermediates thereto, analogues and uses thereof
BRPI0314133A8 (pt) 2002-09-23 2017-09-19 Bristol Myers Squibb Co Processo para isolamento de epotilona b, métodos para cultivo de microorganismo que produza epotilona a ou b e para purifiação de apotilona
WO2004045518A2 (en) 2002-11-15 2004-06-03 Bristol-Myers Squibb Company Open chain prolyl urea-related modulators of androgen receptor function
US7820702B2 (en) 2004-02-04 2010-10-26 Bristol-Myers Squibb Company Sulfonylpyrrolidine modulators of androgen receptor function and method
US7378426B2 (en) 2004-03-01 2008-05-27 Bristol-Myers Squibb Company Fused heterotricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3
US7625923B2 (en) 2004-03-04 2009-12-01 Bristol-Myers Squibb Company Bicyclic modulators of androgen receptor function
US7696241B2 (en) 2004-03-04 2010-04-13 Bristol-Myers Squibb Company Bicyclic compounds as modulators of androgen receptor function and method
EP1824458A1 (en) * 2004-11-18 2007-08-29 Bristol-Myers Squibb Company Enteric coated bead comprising epothilone or an epothilone analog, and preparation and administration thereof
PL1817013T3 (pl) * 2004-11-18 2009-01-30 Bristol Myers Squibb Co Dojelitowa powlekana peletka zawierająca Ixabepilone
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US8017749B2 (en) 2006-12-04 2011-09-13 The Board Of Trustees Of The University Of Illinois Compositions and methods to treat cancer with cupredoxins and CpG rich DNA
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AU2012207142B2 (en) 2011-01-20 2017-04-27 Board Of Regents, The University Of Texas System MRI markers, delivery and extraction systems, and methods of manufacture and use thereof
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CN102993239A (zh) 2011-09-19 2013-03-27 陈小平 离去基团含氨基或烷胺基的丁二酸衍生物的铂类化合物
WO2014075391A1 (zh) 2012-11-17 2014-05-22 北京市丰硕维康技术开发有限责任公司 离去基团是含氨基或烷氨基的丙二酸衍生物的铂类化合物
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Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4138042C2 (de) * 1991-11-19 1993-10-14 Biotechnolog Forschung Gmbh Epothilone, deren Herstellungsverfahren sowie diese Verbindungen enthaltende Mittel
ATE261961T1 (de) * 1995-11-17 2004-04-15 Biotechnolog Forschung Gmbh Epothilon-derivate, ihre herstellung und verwendung
US6441186B1 (en) * 1996-12-13 2002-08-27 The Scripps Research Institute Epothilone analogs
WO1998038192A1 (de) * 1997-02-25 1998-09-03 GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) Seitenkettenmodifizierte epothilone

Also Published As

Publication number Publication date
CN1544436A (zh) 2004-11-10
CA2281105A1 (en) 1998-09-03
AU736062B2 (en) 2001-07-26
EP1201666A2 (de) 2002-05-02
EP0975638B1 (de) 2002-08-07
PT975638E (pt) 2002-12-31
IL131343A (en) 2004-03-28
DK0975638T3 (da) 2002-11-18
HU228851B1 (en) 2013-06-28
BR9807742A (pt) 2000-02-22
PL190422B1 (pl) 2005-12-30
HK1023774A1 (en) 2000-09-22
HUP0002189A2 (hu) 2001-10-28
ES2183338T3 (es) 2003-03-16
DE19880193D2 (de) 2000-08-24
IL131343A0 (en) 2001-01-28
RU2201932C2 (ru) 2003-04-10
NZ337195A (en) 2001-05-25
WO1998038192A1 (de) 1998-09-03
US6359140B1 (en) 2002-03-19
ZA981575B (en) 1998-09-08
HUP0002189A3 (en) 2001-12-28
EP1201666A3 (de) 2003-03-05
NO994071L (no) 1999-10-21
CZ286599A3 (cs) 2000-03-15
NO327211B1 (no) 2009-05-11
CN1128803C (zh) 2003-11-26
EP0975638A1 (de) 2000-02-02
TW480263B (en) 2002-03-21
CZ298027B6 (cs) 2007-05-30
PL335329A1 (en) 2000-04-25
BR9807742B1 (pt) 2010-12-14
CN1248974A (zh) 2000-03-29
AR011878A1 (es) 2000-09-13
DE59805110D1 (de) 2002-09-12
JP2001513098A (ja) 2001-08-28
AU6724998A (en) 1998-09-18
ATE221888T1 (de) 2002-08-15
KR20000075705A (ko) 2000-12-26
KR100494179B1 (ko) 2005-06-10

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