DK0973918T3 - Gærceller, der omfatter mindst to kopier af et önsket gen integreret i det kromosomale genom ved mere end et ikke-ribosomalt RNA-kodende domæne, navnlig med Kluyveromyces - Google Patents

Gærceller, der omfatter mindst to kopier af et önsket gen integreret i det kromosomale genom ved mere end et ikke-ribosomalt RNA-kodende domæne, navnlig med Kluyveromyces

Info

Publication number
DK0973918T3
DK0973918T3 DK98928202T DK98928202T DK0973918T3 DK 0973918 T3 DK0973918 T3 DK 0973918T3 DK 98928202 T DK98928202 T DK 98928202T DK 98928202 T DK98928202 T DK 98928202T DK 0973918 T3 DK0973918 T3 DK 0973918T3
Authority
DK
Denmark
Prior art keywords
desired gene
copies
ribosomal rna
gene integrated
yeast cells
Prior art date
Application number
DK98928202T
Other languages
Danish (da)
English (en)
Inventor
Ooijen Albert Johannes Joseph Van
Bart Willem Swinkels
Cornelia Maria Noordermeer-Van Der Haak Adriana
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Application granted granted Critical
Publication of DK0973918T3 publication Critical patent/DK0973918T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK98928202T 1997-04-11 1998-04-14 Gærceller, der omfatter mindst to kopier af et önsket gen integreret i det kromosomale genom ved mere end et ikke-ribosomalt RNA-kodende domæne, navnlig med Kluyveromyces DK0973918T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97201053 1997-04-11
EP97201637 1997-06-03
PCT/EP1998/002261 WO1998046774A1 (fr) 1997-04-11 1998-04-14 Cellules de levure comprenant au moins deux copies d'un gene desire integree dans le genome chromosomique dans plus d'un domaine codant de l'arn non ribosomique, en particulier avec des kluyveromyces

Publications (1)

Publication Number Publication Date
DK0973918T3 true DK0973918T3 (da) 2008-09-22

Family

ID=26146351

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98928202T DK0973918T3 (da) 1997-04-11 1998-04-14 Gærceller, der omfatter mindst to kopier af et önsket gen integreret i det kromosomale genom ved mere end et ikke-ribosomalt RNA-kodende domæne, navnlig med Kluyveromyces

Country Status (8)

Country Link
EP (1) EP0973918B1 (fr)
JP (1) JP4531868B2 (fr)
AT (1) ATE398181T1 (fr)
AU (1) AU8013798A (fr)
DE (1) DE69839602D1 (fr)
DK (1) DK0973918T3 (fr)
ES (1) ES2308805T3 (fr)
WO (1) WO1998046774A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102597241B (zh) 2009-07-22 2015-09-02 帝斯曼知识产权资产管理有限公司 用于生产感兴趣的化合物的经改进的宿主细胞
AU2018241920B2 (en) 2017-03-29 2022-04-21 Boehringer Ingelheim Rcv Gmbh & Co Kg Recombinant host cell with altered membrane lipid composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE55817B1 (en) * 1982-05-19 1991-01-30 Gist Brocades Nv Cloning system for kluyveromyces species
CA2063592C (fr) * 1989-07-07 2003-01-21 Marco L. F. Giuseppin Procede servant a la preparation d'une proteine au moyen d'un champignon transforme par l'integration multicopie d'un vecteur d'expression
IT1251435B (it) * 1991-09-04 1995-05-09 Sclavo Spa Vettore genetico per la integrazione multipla stabile di sequenze di dna nel genoma dei lieviti kluyveromyces lactis e saccharomyces cerevisiae e plasmidi che lo contengono.
DE69432543T2 (de) * 1993-07-23 2003-12-24 Dsm Nv Selektionmarker-genfreie rekombinante Stämme: Verfahren zur ihrer Herstellung und die Verwendung dieser Stämme

Also Published As

Publication number Publication date
DE69839602D1 (de) 2008-07-24
JP2002514077A (ja) 2002-05-14
EP0973918A1 (fr) 2000-01-26
ATE398181T1 (de) 2008-07-15
EP0973918B1 (fr) 2008-06-11
AU8013798A (en) 1998-11-11
JP4531868B2 (ja) 2010-08-25
WO1998046774A1 (fr) 1998-10-22
ES2308805T3 (es) 2008-12-01

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