DK0970121T3 - Peptidfragmenter af myelin-basisk-protein, deres farmaceutiske sammensætninger og deres anvendelse i behandling af multipel sklerose - Google Patents

Peptidfragmenter af myelin-basisk-protein, deres farmaceutiske sammensætninger og deres anvendelse i behandling af multipel sklerose

Info

Publication number
DK0970121T3
DK0970121T3 DK98914725T DK98914725T DK0970121T3 DK 0970121 T3 DK0970121 T3 DK 0970121T3 DK 98914725 T DK98914725 T DK 98914725T DK 98914725 T DK98914725 T DK 98914725T DK 0970121 T3 DK0970121 T3 DK 0970121T3
Authority
DK
Denmark
Prior art keywords
mbp
residues
levels
amino acid
synthetic peptides
Prior art date
Application number
DK98914725T
Other languages
English (en)
Inventor
Kenneth G Warren
Ingrid Catz
Original Assignee
Univ Alberta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Alberta filed Critical Univ Alberta
Application granted granted Critical
Publication of DK0970121T3 publication Critical patent/DK0970121T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
DK98914725T 1997-04-04 1998-04-03 Peptidfragmenter af myelin-basisk-protein, deres farmaceutiske sammensætninger og deres anvendelse i behandling af multipel sklerose DK0970121T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA2201841A CA2201841C (en) 1997-04-04 1997-04-04 Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
PCT/CA1998/000290 WO1998045327A1 (en) 1997-04-04 1998-04-03 Peptide fragments of myelin basic protein, their pharmaceutical compositions and their use in treating multiple sclerosis

Publications (1)

Publication Number Publication Date
DK0970121T3 true DK0970121T3 (da) 2008-10-20

Family

ID=4160340

Family Applications (2)

Application Number Title Priority Date Filing Date
DK03022727T DK1394178T3 (da) 1997-04-04 1998-04-03 Fremgangsmåde til fastlæggelse af den terapeutiske aktivitet af et MBP-fragment
DK98914725T DK0970121T3 (da) 1997-04-04 1998-04-03 Peptidfragmenter af myelin-basisk-protein, deres farmaceutiske sammensætninger og deres anvendelse i behandling af multipel sklerose

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK03022727T DK1394178T3 (da) 1997-04-04 1998-04-03 Fremgangsmåde til fastlæggelse af den terapeutiske aktivitet af et MBP-fragment

Country Status (21)

Country Link
EP (2) EP0970121B1 (da)
JP (1) JP4173557B2 (da)
AT (2) ATE400582T1 (da)
AU (1) AU751303B2 (da)
CA (2) CA2201841C (da)
CY (2) CY1107445T1 (da)
CZ (1) CZ299535B6 (da)
DE (2) DE69839163T2 (da)
DK (2) DK1394178T3 (da)
ES (2) ES2307317T3 (da)
HK (1) HK1063805A1 (da)
HU (1) HU226768B1 (da)
NO (1) NO325018B1 (da)
NZ (1) NZ338091A (da)
PL (1) PL191965B1 (da)
PT (2) PT1394178E (da)
RO (1) RO119303B1 (da)
RU (1) RU2198893C2 (da)
SK (1) SK285815B6 (da)
UA (1) UA60331C2 (da)
WO (1) WO1998045327A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1541106A (zh) 2001-06-11 2004-10-27 转新疗法公司 用维生素b12和治疗剂联合治疗病毒性、增殖性和炎性疾病的方法
CN101353094B (zh) * 2008-09-22 2011-04-13 刘年路 密闭瓶状软塑料袋及其应用
EA024832B1 (ru) 2009-10-12 2016-10-31 ЛАЙФБИО ЛАБОРАТОРИС ЭлЭлСи Олигопептид, связывающий гидролизующие аутоантитела к основному белку миелина mbp, композиции и способ лечения рассеянного склероза
RU2646817C1 (ru) * 2016-12-27 2018-03-07 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) Пептид из состава тяжелой цепи иммуноглобулина человека, пригодный для лечения рассеянного склероза

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2053799C (en) * 1991-10-22 2002-03-12 Kenneth G. Warren Synthetic peptide specificity of anti-myelin basic protein from multiple sclerosis cerebrospinal fluid
US5817629A (en) * 1991-10-22 1998-10-06 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
JP3434510B2 (ja) * 1992-04-09 2003-08-11 オートイミューン インク ミエリン塩基性タンパク質のペプチドフラグメントを用いたｔ‐細胞増殖の抑制
US5824315A (en) * 1993-10-25 1998-10-20 Anergen, Inc. Binding affinity of antigenic peptides for MHC molecules
EP0787147A1 (en) * 1994-10-25 1997-08-06 Immulogic Pharmaceutical Corporation Compositions and treatment for multiple sclerosis
US6329499B1 (en) * 1994-11-18 2001-12-11 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogues of human myelin basic protein

Also Published As

Publication number Publication date
JP2001518885A (ja) 2001-10-16
HU226768B1 (en) 2009-09-28
ES2307317T3 (es) 2008-11-16
DE69839163T2 (de) 2009-02-12
RO119303B1 (ro) 2004-07-30
CA2494338C (en) 2007-07-17
CY1107445T1 (el) 2012-12-19
NO994806L (no) 1999-12-06
AU751303B2 (en) 2002-08-15
AU6913098A (en) 1998-10-30
HUP0000812A2 (hu) 2000-09-28
DE69839694D1 (de) 2008-08-21
EP1394178B1 (en) 2008-02-20
DK1394178T3 (da) 2008-05-26
CZ299535B6 (cs) 2008-08-27
CA2201841C (en) 2010-01-26
UA60331C2 (uk) 2003-10-15
JP4173557B2 (ja) 2008-10-29
CA2494338A1 (en) 1998-10-04
HUP0000812A3 (en) 2000-10-30
HK1063805A1 (en) 2005-01-14
NO325018B1 (no) 2008-01-14
CZ9903464A3 (cs) 2000-11-15
ES2299657T3 (es) 2008-06-01
WO1998045327A1 (en) 1998-10-15
PL336085A1 (en) 2000-06-05
EP0970121B1 (en) 2008-07-09
DE69839163D1 (de) 2008-04-03
PL191965B1 (pl) 2006-07-31
CA2201841A1 (en) 1998-10-04
EP0970121A1 (en) 2000-01-12
CY1108239T1 (el) 2014-02-12
NO994806D0 (no) 1999-10-01
PT970121E (pt) 2008-09-22
RU2198893C2 (ru) 2003-02-20
EP1394178A1 (en) 2004-03-03
SK285815B6 (sk) 2007-08-02
NZ338091A (en) 2001-10-26
ATE400582T1 (de) 2008-07-15
PT1394178E (pt) 2008-04-15
ATE386941T1 (de) 2008-03-15
SK132999A3 (en) 2000-06-12

Similar Documents

Publication Publication Date Title
NZ293910A (en) Peptides useful in immunoregulation of antibodies to human myelin basic protein, pharmaceutical compositions and method of treatment
ATE425181T1 (de) Therapeutische zusammensetzungen aus antikorper und antisens nukleinsäuren gegen serrate
ATE108662T1 (de) Antimikrobielle peptide, zusammensetzungen, die diese enthalten, und verwendungen daraus.
AU2750092A (en) Synthetic peptide specificity of anti-myelin basic protein from multiple sclerosis cerebrospinal fluid
CY1108239T1 (el) Θραυσματα πεπτιδιου της βασικης πρωτεϊνης της μυελινης, οι φαρμακευτικες τους συνθεσεις και η χρηση τους στη θεραπεια της σκληρυνσης κατα πλακας
NZ335835A (en) Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
EP0342015A3 (en) Peptides, their use and pharmaceutical compositions containing them