DK0954333T3 - Oplöselige lymfotoksin-beta-receptorer, anti-lymfotoksinreceptor-antistoffer og anti-lymfotoksin-ligandantistoffer som terapeutiske midler til behandling af immunologiske sygdomme - Google Patents

Oplöselige lymfotoksin-beta-receptorer, anti-lymfotoksinreceptor-antistoffer og anti-lymfotoksin-ligandantistoffer som terapeutiske midler til behandling af immunologiske sygdomme

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Publication number
DK0954333T3
DK0954333T3 DK97913798T DK97913798T DK0954333T3 DK 0954333 T3 DK0954333 T3 DK 0954333T3 DK 97913798 T DK97913798 T DK 97913798T DK 97913798 T DK97913798 T DK 97913798T DK 0954333 T3 DK0954333 T3 DK 0954333T3
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Prior art keywords
lymphotoxin
antibodies
treatment
therapeutic agents
immunological diseases
Prior art date
Application number
DK97913798T
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Danish (da)
English (en)
Inventor
Jeffrey Browning
Paul D Rennert
Paula Susan Hochman
Fabienne Mackay
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Biogen Idec Inc
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Publication date
Application filed by Biogen Idec Inc filed Critical Biogen Idec Inc
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Publication of DK0954333T3 publication Critical patent/DK0954333T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241Tumor Necrosis Factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK97913798T 1996-10-25 1997-10-24 Oplöselige lymfotoksin-beta-receptorer, anti-lymfotoksinreceptor-antistoffer og anti-lymfotoksin-ligandantistoffer som terapeutiske midler til behandling af immunologiske sygdomme DK0954333T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2906096P 1996-10-25 1996-10-25

Publications (1)

Publication Number Publication Date
DK0954333T3 true DK0954333T3 (da) 2006-10-23

Family

ID=21847003

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97913798T DK0954333T3 (da) 1996-10-25 1997-10-24 Oplöselige lymfotoksin-beta-receptorer, anti-lymfotoksinreceptor-antistoffer og anti-lymfotoksin-ligandantistoffer som terapeutiske midler til behandling af immunologiske sygdomme

Country Status (26)

Country Link
EP (1) EP0954333B1 (pt)
JP (1) JP4299887B2 (pt)
KR (1) KR100584704B1 (pt)
CN (2) CN100382844C (pt)
AT (1) ATE331531T1 (pt)
AU (1) AU726357B2 (pt)
BG (1) BG63565B1 (pt)
BR (1) BR9712670A (pt)
CA (1) CA2269614A1 (pt)
CZ (1) CZ142899A3 (pt)
DE (1) DE69736244T2 (pt)
DK (1) DK0954333T3 (pt)
EA (1) EA002983B1 (pt)
EE (1) EE05213B1 (pt)
ES (1) ES2268727T3 (pt)
HK (1) HK1025500A1 (pt)
HU (1) HU226467B1 (pt)
IL (1) IL129527A (pt)
IS (1) IS5031A (pt)
NO (1) NO328540B1 (pt)
NZ (1) NZ335353A (pt)
PL (1) PL190617B1 (pt)
PT (1) PT954333E (pt)
SK (1) SK55399A3 (pt)
TR (1) TR199901636T2 (pt)
WO (1) WO1998017313A2 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925351A (en) 1995-07-21 1999-07-20 Biogen, Inc. Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease
US6140467A (en) * 1997-07-07 2000-10-31 La Jolla Institute For Allergy And Immunology Ligand for herpes simplex virus entry mediator and methods of use
US6998108B1 (en) 1997-07-07 2006-02-14 La Jolla Institute For Allergy And Immunology Antibodies to p30 polypeptides and methods making and using same
US7118742B2 (en) 1997-07-07 2006-10-10 La Jolla Institute For Allergy And Immunology Ligand for herpes simplex virus entry mediator and methods of use
PT1119370E (pt) * 1998-10-09 2006-09-29 Univ Emory Inversao do estado de choque sistemico e de dificuldade respiratoria originado por inducao viral por meio do bloqueio da via da linfotoxina beta
TR200504220T2 (tr) * 1998-12-17 2007-04-24 Biogen Idec Ma Inc. Aktif limfotoksin-beta reseptör imunoglobülin şimeAktif limfotoksin-beta reseptör imunoglobülin şimerik proteinlerinin yüksek düzey ifadesi ve saflaştrik proteinlerinin yüksek düzey ifadesi ve saflaştırılması için bir yöntem.ırılması için bir yöntem.
TR200103841T2 (tr) * 1999-06-28 2002-06-21 Basf Aktiengesellschaft Tümör büyümesini önlemek için yöntem.
DE19939653A1 (de) * 1999-08-13 2001-02-22 Thomas Huenig Verwendung CD28 spezifischer monoklonaler Antikörper zur Herstellung einer pharmazeutischen Zusammensetzung
WO2001079496A2 (en) * 2000-03-13 2001-10-25 La Jolla Institute For Allergy And Immunology Ligand for herpes simplex virus entry mediator and methods of use
EP1274840B1 (en) * 2000-04-12 2007-06-20 La Jolla Institute For Allergy And Immunology Ligand for herpes simplex virus entry mediator and methods of use
AU2003303339A1 (en) * 2002-12-20 2004-07-22 Biogen Idec Ma Inc. Lymphotoxin beta receptor agents in combination with chemotherapeutic agents
TWI414531B (zh) 2006-10-12 2013-11-11 Genentech Inc 淋巴毒素α之抗體
US8067375B2 (en) 2006-10-20 2011-11-29 Biogen Idec Ma Inc. Treatment of demyelinating disorders with soluble lymphotoxin-β-receptor
US8338376B2 (en) 2006-10-20 2012-12-25 Biogen Idec Ma Inc. Compositions comprising variant LT-B-R-IG fusion proteins
EP2435477A1 (en) * 2009-05-28 2012-04-04 Glaxo Group Limited Antigen-binding proteins
US20210253723A1 (en) * 2018-06-15 2021-08-19 Universität Bern LIGANDS TO LIGHT OR ITS RECEPTOR LTßR FOR USE IN HAEMATOLOGIC MALIGNANCIES
KR102360196B1 (ko) 2019-10-30 2022-02-08 주식회사 친환경테크 다용도 시트 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69334224D1 (de) * 1992-12-04 2008-07-17 Biogen Idec Inc Lymphotoxin-beta, lymphotoxin-beta komplexe, pharmazeutische zubereitungen und therapeutische verwendungen davon
US5925351A (en) * 1995-07-21 1999-07-20 Biogen, Inc. Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease

Also Published As

Publication number Publication date
HK1025500A1 (en) 2000-11-17
CA2269614A1 (en) 1998-04-30
NO328540B1 (no) 2010-03-15
IS5031A (is) 1999-04-21
BR9712670A (pt) 1999-10-19
AU5089698A (en) 1998-05-15
HUP9904516A3 (en) 2002-09-30
KR20000052800A (ko) 2000-08-25
EP0954333A2 (en) 1999-11-10
JP2001502697A (ja) 2001-02-27
PL190617B1 (pl) 2005-12-30
CZ142899A3 (cs) 1999-07-14
HUP9904516A2 (hu) 2000-05-28
NZ335353A (en) 2000-09-29
BG63565B1 (bg) 2002-05-31
HU226467B1 (en) 2008-12-29
CN100382844C (zh) 2008-04-23
CN1237910A (zh) 1999-12-08
EE05213B1 (et) 2009-10-15
PL332972A1 (en) 1999-10-25
EA002983B1 (ru) 2002-12-26
AU726357B2 (en) 2000-11-02
PT954333E (pt) 2006-10-31
NO991926L (no) 1999-06-25
SK55399A3 (en) 2000-10-09
WO1998017313A3 (en) 1998-07-30
BG103416A (en) 2000-01-31
EA199900409A1 (ru) 2000-02-28
EE9900146A (et) 1999-12-15
DE69736244T2 (de) 2007-05-31
IL129527A (en) 2006-12-10
ES2268727T3 (es) 2007-03-16
WO1998017313A2 (en) 1998-04-30
TR199901636T2 (xx) 1999-09-21
CN101239186A (zh) 2008-08-13
ATE331531T1 (de) 2006-07-15
IL129527A0 (en) 2000-02-29
KR100584704B1 (ko) 2006-05-30
NO991926D0 (no) 1999-04-22
JP4299887B2 (ja) 2009-07-22
EP0954333B1 (en) 2006-06-28
DE69736244D1 (de) 2006-08-10

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