DK0946146T3 - Anvendelse af vandige lægemiddelfomuleringer til produktion af drivgasfrie aerosoler - Google Patents
Anvendelse af vandige lægemiddelfomuleringer til produktion af drivgasfrie aerosolerInfo
- Publication number
- DK0946146T3 DK0946146T3 DK97952949T DK97952949T DK0946146T3 DK 0946146 T3 DK0946146 T3 DK 0946146T3 DK 97952949 T DK97952949 T DK 97952949T DK 97952949 T DK97952949 T DK 97952949T DK 0946146 T3 DK0946146 T3 DK 0946146T3
- Authority
- DK
- Denmark
- Prior art keywords
- propellant
- production
- drug formulations
- aqueous drug
- free aerosols
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Otolaryngology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19653969A DE19653969A1 (de) | 1996-12-20 | 1996-12-20 | Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole |
PCT/EP1997/007062 WO1998027959A2 (de) | 1996-12-20 | 1997-12-16 | Neue wässerige arzneimittelzubereitungen zur erzeugung treibgasfreier aerosole |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0946146T3 true DK0946146T3 (da) | 2003-04-22 |
Family
ID=7815979
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97952949T DK0946146T3 (da) | 1996-12-20 | 1997-12-16 | Anvendelse af vandige lægemiddelfomuleringer til produktion af drivgasfrie aerosoler |
Country Status (39)
Country | Link |
---|---|
US (3) | US20010008632A1 (id) |
EP (2) | EP0946146B1 (id) |
JP (1) | JP4659160B2 (id) |
KR (1) | KR100496723B1 (id) |
CN (1) | CN1097455C (id) |
AR (1) | AR008721A1 (id) |
AT (1) | ATE235887T1 (id) |
AU (1) | AU740543B2 (id) |
BG (1) | BG64433B1 (id) |
BR (1) | BRPI9713596C1 (id) |
CA (1) | CA2275392C (id) |
CO (1) | CO4920211A1 (id) |
DE (2) | DE19653969A1 (id) |
DK (1) | DK0946146T3 (id) |
EE (1) | EE03949B1 (id) |
EG (1) | EG23981A (id) |
ES (1) | ES2196388T3 (id) |
HK (1) | HK1022846A1 (id) |
HR (1) | HRP970694B1 (id) |
HU (2) | HU227012B1 (id) |
ID (1) | ID22481A (id) |
IL (1) | IL130464A (id) |
MY (1) | MY124547A (id) |
NO (1) | NO320652B1 (id) |
NZ (1) | NZ336825A (id) |
PE (1) | PE32899A1 (id) |
PL (1) | PL189511B1 (id) |
PT (1) | PT946146E (id) |
RS (1) | RS49803B (id) |
RU (1) | RU2219906C2 (id) |
SA (1) | SA97180756B1 (id) |
SI (1) | SI0946146T1 (id) |
SK (1) | SK282910B6 (id) |
TR (1) | TR199901408T2 (id) |
TW (1) | TW438605B (id) |
UA (1) | UA64736C2 (id) |
UY (1) | UY24813A1 (id) |
WO (1) | WO1998027959A2 (id) |
ZA (1) | ZA9711370B (id) |
Families Citing this family (90)
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DE19733651A1 (de) * | 1997-08-04 | 1999-02-18 | Boehringer Ingelheim Pharma | Wässrige Aerosolzubereitungen enthaltend biologisch aktive Markomoleküle und Verfahren zur Erzeugung entsprechender Aerosole |
DE19808295A1 (de) | 1998-02-27 | 1999-11-11 | Boehringer Ingelheim Int | Behälter für eine medizinische Flüssigkeit |
DE19847968A1 (de) * | 1998-10-17 | 2000-04-20 | Boehringer Ingelheim Pharma | Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen |
SE9803770D0 (sv) * | 1998-11-05 | 1998-11-05 | Astra Ab | Dry powder pharmaceutical formulation |
DE19940713A1 (de) | 1999-02-23 | 2001-03-01 | Boehringer Ingelheim Int | Kartusche für eine Flüssigkeit |
DE19921693A1 (de) * | 1999-05-12 | 2000-11-16 | Boehringer Ingelheim Pharma | Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika |
US20100197719A1 (en) * | 1999-05-12 | 2010-08-05 | Boehringer Ingelheim Pharma Kg | Medicament compositions containing anticholinergically-effective compounds and betamimetics |
US20040002548A1 (en) * | 1999-05-12 | 2004-01-01 | Boehringer Ingelheim Pharma Kg | Medicament compositions containing anticholinergically-effective compounds and betamimetics |
DE19954516A1 (de) * | 1999-11-12 | 2001-05-17 | Boehringer Ingelheim Int | Epinastin-haltige Lösungen |
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KR100983208B1 (ko) * | 2000-10-31 | 2010-09-20 | 베링거 잉겔하임 파르마 게엠베하 운트 코 카게 | 티오트로퓸 염을 함유하는 용액의 흡입성 제형 |
DE10062712A1 (de) * | 2000-12-15 | 2002-06-20 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Corticosteroiden |
US20020193392A1 (en) * | 2000-11-13 | 2002-12-19 | Christel Schmelzer | Pharmaceutical compositions based on tiotropium salts of salts of salmeterol |
DE10111843A1 (de) * | 2001-03-13 | 2002-09-19 | Boehringer Ingelheim Pharma | Verbindungen zur Behandlung von inflammatorischen Erkrankungen |
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DE10136555A1 (de) | 2001-07-27 | 2003-02-13 | Boehringer Ingelheim Int | Optimierte Verfahren zur Bestimmung der Aerosol-Partikelgrößenverteilung und Vorrichtung zur Durchführung derartiger Verfahren |
DE60209511T2 (de) * | 2001-09-18 | 2006-10-05 | Nycomed Danmark Aps | Zusammensetzungen zur behandlung des schnupfens, welche ipratropium und xylometazolin enthalten |
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US9808471B2 (en) * | 2003-04-16 | 2017-11-07 | Mylan Specialty Lp | Nasal pharmaceutical formulations and methods of using the same |
US20040265238A1 (en) * | 2003-06-27 | 2004-12-30 | Imtiaz Chaudry | Inhalable formulations for treating pulmonary hypertension and methods of using same |
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ES2612257T3 (es) * | 2011-05-03 | 2017-05-16 | Chiesi Farmaceutici S.P.A. | Formulación de suspensión mejorada de dipropionato de beclometasona para administración mediante inhalación |
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CN104487075A (zh) | 2012-02-29 | 2015-04-01 | 普马特里克斯公司 | 可吸入干粉剂 |
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RU2479304C1 (ru) * | 2012-05-29 | 2013-04-20 | Шолекс Девелопмент Гмбх, | Стабильный раствор фенотерола гидробромида |
RU2493827C1 (ru) * | 2012-10-03 | 2013-09-27 | Шолекс Девелопмент Гмбх | Стабильный комбинированный раствор фенотерола гидробромида и ипратропия бромида |
CN105324106A (zh) | 2013-04-01 | 2016-02-10 | 普马特里克斯营业公司 | 噻托铵干粉 |
EP2835146B1 (en) | 2013-08-09 | 2020-09-30 | Boehringer Ingelheim International GmbH | Nebulizer |
JP6643231B2 (ja) | 2013-08-09 | 2020-02-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
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DE19536902A1 (de) * | 1995-10-04 | 1997-04-10 | Boehringer Ingelheim Int | Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung |
DE19620509A1 (de) * | 1996-05-22 | 1997-11-27 | Hoechst Ag | Verwendung nicht-peptidischer Bradykinin-Antagonisten zur Behandlung und Prävention von chronisch-fibrogenetischen Lebererkrankungen, akuten Lebererkrankungen und den damit verbundenen Komplikationen |
EP0808627A2 (de) * | 1996-05-22 | 1997-11-26 | Hoechst Aktiengesellschaft | Verwendung nicht-peptidischer Bradykinin-Antagonisten zur Behandlung und Prävention von chronisch-fibrogenetischen Lebererkrankungen, akuten Lebererkrankungen und den damit verbundenen Komplikationen |
US5976573A (en) * | 1996-07-03 | 1999-11-02 | Rorer Pharmaceutical Products Inc. | Aqueous-based pharmaceutical composition |
DE19644646A1 (de) * | 1996-10-26 | 1998-04-30 | Mann & Hummel Filter | Filter, insbesondere zur Filtrierung des Schmieröls einer Brennkraftmaschine |
US20030215396A1 (en) * | 1999-09-15 | 2003-11-20 | Boehringer Ingelheim Pharma Kg | Method for the production of propellant gas-free aerosols from aqueous medicament preparations |
US20060239930A1 (en) * | 1997-08-04 | 2006-10-26 | Herbert Lamche | Process for nebulizing aqueous compositions containing highly concentrated insulin |
DE19847969A1 (de) * | 1998-10-17 | 2000-04-20 | Boehringer Ingelheim Pharma | Lagerfähig flüssige Formulierung mit Formoterol |
DE19921693A1 (de) * | 1999-05-12 | 2000-11-16 | Boehringer Ingelheim Pharma | Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika |
US20020137764A1 (en) * | 2000-10-31 | 2002-09-26 | Karin Drechsel | Inhalable formulation of a solution containing a tiotropium salt |
US20020111363A1 (en) * | 2000-10-31 | 2002-08-15 | Karin Drechsel | Inhalable formulation of a solution containing a tiotropium salt |
US20020193392A1 (en) * | 2000-11-13 | 2002-12-19 | Christel Schmelzer | Pharmaceutical compositions based on tiotropium salts of salts of salmeterol |
US20040019073A1 (en) * | 2002-04-11 | 2004-01-29 | Boehringer Ingelheim Pharma Gmbh Co. Kg | Aerosol formulation for inhalation containing a tiotropium salt |
-
1996
- 1996-12-20 DE DE19653969A patent/DE19653969A1/de not_active Ceased
-
1997
- 1997-12-16 US US09/331,023 patent/US20010008632A1/en not_active Abandoned
- 1997-12-16 IL IL13046497A patent/IL130464A/en not_active IP Right Cessation
- 1997-12-16 KR KR10-1999-7005535A patent/KR100496723B1/ko not_active IP Right Cessation
- 1997-12-16 PT PT97952949T patent/PT946146E/pt unknown
- 1997-12-16 CA CA002275392A patent/CA2275392C/en not_active Expired - Lifetime
- 1997-12-16 EE EEP199900307A patent/EE03949B1/xx unknown
- 1997-12-16 DK DK97952949T patent/DK0946146T3/da active
- 1997-12-16 SI SI9730537T patent/SI0946146T1/xx unknown
- 1997-12-16 TR TR1999/01408T patent/TR199901408T2/xx unknown
- 1997-12-16 AT AT97952949T patent/ATE235887T1/de active
- 1997-12-16 RU RU99116025/15A patent/RU2219906C2/ru active
- 1997-12-16 ES ES97952949T patent/ES2196388T3/es not_active Expired - Lifetime
- 1997-12-16 RS YUP-284/99A patent/RS49803B/sr unknown
- 1997-12-16 ID IDW990549A patent/ID22481A/id unknown
- 1997-12-16 CN CN97180735A patent/CN1097455C/zh not_active Expired - Lifetime
- 1997-12-16 EP EP97952949A patent/EP0946146B1/de not_active Expired - Lifetime
- 1997-12-16 NZ NZ336825A patent/NZ336825A/en not_active IP Right Cessation
- 1997-12-16 PE PE1997001120A patent/PE32899A1/es not_active IP Right Cessation
- 1997-12-16 UA UA99074151A patent/UA64736C2/uk unknown
- 1997-12-16 JP JP52833698A patent/JP4659160B2/ja not_active Expired - Lifetime
- 1997-12-16 AU AU56636/98A patent/AU740543B2/en not_active Expired
- 1997-12-16 SK SK814-99A patent/SK282910B6/sk not_active IP Right Cessation
- 1997-12-16 HU HU0000520A patent/HU227012B1/hu unknown
- 1997-12-16 BR BRPI9713596A patent/BRPI9713596C1/pt not_active IP Right Cessation
- 1997-12-16 WO PCT/EP1997/007062 patent/WO1998027959A2/de active IP Right Grant
- 1997-12-16 HU HU0600044A patent/HU228494B1/hu unknown
- 1997-12-16 EP EP02010785A patent/EP1230916A3/de not_active Withdrawn
- 1997-12-16 PL PL97334185A patent/PL189511B1/pl unknown
- 1997-12-16 DE DE59709722T patent/DE59709722D1/de not_active Expired - Lifetime
- 1997-12-17 UY UY24813A patent/UY24813A1/es not_active IP Right Cessation
- 1997-12-18 ZA ZA9711370A patent/ZA9711370B/xx unknown
- 1997-12-18 HR HR970694A patent/HRP970694B1/xx not_active IP Right Cessation
- 1997-12-18 EG EG135397A patent/EG23981A/xx active
- 1997-12-18 CO CO97074008A patent/CO4920211A1/es unknown
- 1997-12-19 MY MYPI97006172A patent/MY124547A/en unknown
- 1997-12-19 AR ARP970106019A patent/AR008721A1/es active IP Right Grant
- 1997-12-20 TW TW086119428A patent/TW438605B/zh not_active IP Right Cessation
- 1997-12-30 SA SA97180756A patent/SA97180756B1/ar unknown
-
1999
- 1999-06-10 BG BG103482A patent/BG64433B1/bg active Active
- 1999-06-18 NO NO19993004A patent/NO320652B1/no not_active IP Right Cessation
-
2000
- 2000-03-31 HK HK00101995A patent/HK1022846A1/xx not_active IP Right Cessation
-
2008
- 2008-12-18 US US12/338,812 patent/US20090099225A1/en not_active Abandoned
-
2009
- 2009-03-30 US US12/413,828 patent/US20090185983A1/en not_active Abandoned
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