DK0927560T3 - Indretning til intraokulær overförsel af aktive produkter ved iontophorese - Google Patents

Indretning til intraokulær overförsel af aktive produkter ved iontophorese

Info

Publication number
DK0927560T3
DK0927560T3 DK98403189T DK98403189T DK0927560T3 DK 0927560 T3 DK0927560 T3 DK 0927560T3 DK 98403189 T DK98403189 T DK 98403189T DK 98403189 T DK98403189 T DK 98403189T DK 0927560 T3 DK0927560 T3 DK 0927560T3
Authority
DK
Denmark
Prior art keywords
iontophoresis
reservoir
active products
electrode
active
Prior art date
Application number
DK98403189T
Other languages
Danish (da)
English (en)
Inventor
Jean-Marie Parel
Francine Behar
Original Assignee
Optis France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Optis France filed Critical Optis France
Application granted granted Critical
Publication of DK0927560T3 publication Critical patent/DK0927560T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
DK98403189T 1998-01-05 1998-12-17 Indretning til intraokulær overförsel af aktive produkter ved iontophorese DK0927560T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9800009A FR2773320B1 (fr) 1998-01-05 1998-01-05 Dispositif pour le transfert intraoculaire de produits actifs par iontophorese

Publications (1)

Publication Number Publication Date
DK0927560T3 true DK0927560T3 (da) 2005-08-15

Family

ID=9521510

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98403189T DK0927560T3 (da) 1998-01-05 1998-12-17 Indretning til intraokulær overförsel af aktive produkter ved iontophorese

Country Status (13)

Country Link
US (1) US6154671A (de)
EP (2) EP0927560B1 (de)
JP (1) JP4308353B2 (de)
KR (1) KR100551706B1 (de)
AT (2) ATE437672T1 (de)
BR (1) BR9900009A (de)
CA (1) CA2257749C (de)
DE (2) DE69841028D1 (de)
DK (1) DK0927560T3 (de)
ES (2) ES2327636T3 (de)
FR (1) FR2773320B1 (de)
IL (1) IL127711A (de)
PT (1) PT927560E (de)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6101411A (en) * 1998-09-24 2000-08-08 Newsome; David A. Dilation enhancer
US7346389B1 (en) * 1998-09-24 2008-03-18 Newsome David A Dilation enhancer with pre-medicated contact lenses
US6319240B1 (en) * 1999-05-25 2001-11-20 Iomed, Inc. Methods and apparatus for ocular iontophoresis
US6728573B1 (en) 2000-02-23 2004-04-27 Iomed, Inc. Ocular iontophoretic apparatus handle
US7252655B2 (en) 1999-05-25 2007-08-07 Iomed, Inc. Ocular iontophoretic apparatus handle
US6539251B2 (en) 1999-05-25 2003-03-25 Iomed, Inc. Ocular iontophoretic apparatus
US6546283B1 (en) 2000-10-18 2003-04-08 Iomed, Inc. High current density iontophoretic device and method of use thereof
US20030045830A1 (en) * 2001-04-17 2003-03-06 De Bizemont Therese Gene therapy with chimeric oligonucleotides delivered by a method comprising a step of iontophoresis
US20040106965A1 (en) * 2001-06-29 2004-06-03 Chow Alan Y. Methods and apparatus for treatment of degenerative retinal disease via indirect electrical stimulation
US20050004625A1 (en) * 2001-06-29 2005-01-06 Chow Alan Y. Treatment of degenerative retinal disease via electrical stimulation of surface structures
US7031776B2 (en) * 2001-06-29 2006-04-18 Optobionics Methods for improving damaged retinal cell function
US20050033202A1 (en) * 2001-06-29 2005-02-10 Chow Alan Y. Mechanically activated objects for treatment of degenerative retinal disease
EP1418919A4 (de) * 2001-07-20 2007-06-13 Iomed Inc Verwendung von 5-fluorouracil, verabreicht durch inotophorese, als hemmer der zellproliferation im auge, der bulbären und palpebralen konjunktiva, dem augenlid, dem periorbitalen geweben und der haut
WO2003007961A1 (en) * 2001-07-20 2003-01-30 Iomed, Inc. Methods for treating neoplastic, angiogenic, fibroplastic, and/or immunosuppresive ocular irregularities via administration of methotrexate based medicaments, and ocular iontophoretic devices for delivering methotrexate based medicaments
FR2830766B1 (fr) 2001-10-12 2004-03-12 Optis France Sa Dispositif de delivrance de medicaments par iontophorese transpalpebrale
FR2830767B1 (fr) * 2001-10-12 2004-03-12 Optis France Sa Dispositif de delivrance de medicaments par iontophorese ou electroporation introculaire
FR2836832B1 (fr) 2002-03-08 2005-02-04 Optis France Sa Ensemble de connexion a usage medical pour le transfert de fluides
CA2484512C (en) 2002-05-17 2013-04-16 Othera Pharmaceuticals, Inc. Treatment of cataracts and other ophthalmic diseases
FR2851912B1 (fr) 2003-03-03 2005-05-13 Optis France Sa Connecteur d'alimentation uniforme pour des dispositifs de delivrance de principes actifs
US7825134B2 (en) * 2003-05-19 2010-11-02 Othera Holding, Inc. Amelioration of cataracts, macular degeneration and other ophthalmic diseases
US7589107B2 (en) 2003-05-19 2009-09-15 Othera Holding, Inc. Amelioration of vitrectomy-induced cataracts
FR2855761B1 (fr) * 2003-06-03 2006-02-24 Optis France Sa Dispositif oculaire de delivrance variable de principes actifs par iontophorese
ZA200604403B (en) * 2003-11-20 2007-09-26 Othera Pharmaceuticals Inc Amelioration of macular degeneration and other ophthalmic diseases
CA2556222C (en) * 2004-02-06 2014-01-28 Scyfix Llc Treatment of vision disorders using electrical, light, and/or sound energy
AU2005247122C1 (en) 2004-04-30 2012-02-02 Eyegate Pharma S.A. Irritation-reducing ocular iontophoretic device
FR2869531B1 (fr) 2004-04-30 2006-07-14 Optis France Sa Sa Dispositif de iontophorese oculaire diminuant les irritations
BRPI0511462A (pt) * 2004-05-25 2007-12-26 Othera Pharmaceuticals Inc medicamentos e pró-medicamentos óculo-seletivos
US20060089590A1 (en) * 2004-10-27 2006-04-27 John Higuchi Methods and devices for sustained in-vivo release of an active agent
US8262715B2 (en) * 2004-11-23 2012-09-11 Eye Delivery System, Llc Medical device and method for temperature control and treatment of the eye and surrounding tissues via magnetic drug therapy
EP1816980B1 (de) * 2004-11-23 2011-03-16 Edward Wong Medizinische vorrichtung zur temperaturregelung und behandlung des auges sowie des umgebenden gewebes
US20070282282A1 (en) * 2004-11-23 2007-12-06 Wong Edward K Jr Medical device and method for temperature control and treatment of the eye and surrounding tissues
WO2006072887A1 (en) * 2005-01-05 2006-07-13 Eyegate Pharma Sa Ocular iontophoresis device for delivering sirna and aptamers
EP1871890B1 (de) * 2005-04-18 2011-06-15 INSERM (Institut National de la Santé et de la Recherche Médicale) Verfahren und vorrichtungen zur abgabe eines therapeutischen produkts an den augapfel eines patienten
US20080312283A1 (en) * 2005-05-26 2008-12-18 Othera Pharmaceuticals, Inc. Use of Hydroxylamine Derivates for Inhibiting Vitrectomy-Induced Cataracts
US20070260171A1 (en) * 2005-09-27 2007-11-08 Higuchi John W Intraocular iontophoretic device and associated methods
US8755880B2 (en) * 2005-10-24 2014-06-17 Aciont, Inc. Intraocular iontophoretic device and associated methods
EP1940507A4 (de) * 2005-10-24 2011-04-20 Aciont Inc Intraokulare iontophoretische vorrichtung und relevante verfahren
US8634907B2 (en) 2005-10-24 2014-01-21 Aciont, Inc. Intraocular iontophoretic device and associated methods
US8099162B2 (en) 2005-11-29 2012-01-17 Eyegate Pharma, S.A.S. Ocular iontophoresis device
FR2893852B1 (fr) * 2005-11-29 2010-09-03 Eyegate Pharma Sa Dispositif d'iontophorese oculaire
US20070203190A1 (en) * 2006-02-22 2007-08-30 Ghanshyam Patil Hydroxylamines and derivatives for the inhibition of complement activation
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
JPWO2007123142A1 (ja) * 2006-04-20 2009-09-03 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置
US20070299386A1 (en) * 2006-06-23 2007-12-27 Minu, L.L.C. Delivery of an ocular agent using iontophoresis
WO2008013913A2 (en) * 2006-07-26 2008-01-31 Aciont, Inc. Method and device for minimally invasive site specific ocular drug delivery
US8923961B2 (en) 2006-10-18 2014-12-30 The Cleveland Clinic Foundation Electrode assembly for delivering a therapeutic agent into ocular tissue
CN105998028A (zh) 2007-02-22 2016-10-12 科尔比制药公司 羟胺化合物及其用法
US9125807B2 (en) 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
US8480638B2 (en) * 2007-10-04 2013-07-09 Aciont, Inc. Intraocular iontophoretic device and associated methods
MX2010006019A (es) * 2007-12-05 2010-08-04 Eyegate Pharma S A S Metodos para administrar acido ribonucleico pequeño de interferencia (arnsi) mediante iontoforesis.
BRPI0908229A8 (pt) 2008-02-25 2017-10-10 Eyegate Pharma S A S Uso de um corticosteróide, derivado de corticosteróide, pró-fármaco ou sal deste, kit e dispositivo para dispensar iontoforeticamente um corticosteróide, derivado de corticosteróide, pró-fármaco ou sal deste no olho de um paciente para tratar um distúrbio ocular mediado por inflamação no referido paciente, e, formulação apropriada para dispensação iontoforética ocular de um corticosteróide, derivado de corticosteróide, pró-fármaco ou sal deste no olho de um paciente
FR2928536B1 (fr) 2008-03-14 2012-04-27 Inst Nat Sante Rech Med Dispositif d'injection dans l'oeil
US9180292B2 (en) 2008-12-31 2015-11-10 Eyegate Pharmaceuticals, Inc. System and method for ocular iontophoresis with buffering
WO2010093873A2 (en) 2009-02-12 2010-08-19 Incept, Llc Drug delivery through hydrogel plugs
EP2555751B8 (de) 2010-04-03 2018-02-14 Praful Doshi Verfahren zum beschichtigen von einer kontaktlinse
US10413506B2 (en) 2010-04-03 2019-09-17 Praful Doshi Medical devices including medicaments and methods of making and using same including enhancing comfort, enhancing drug penetration, and treatment of myopia
US8993626B2 (en) 2010-06-25 2015-03-31 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of treatment using sterculic acid
US8961501B2 (en) 2010-09-17 2015-02-24 Incept, Llc Method for applying flowable hydrogels to a cornea
MX347934B (es) 2011-01-12 2017-05-18 Sooft Italia Spa Dispositivo y método para el suministro de riboflavina en la córnea, mediante iontoforesis, para el tratamiento de queratocono.
WO2012162459A1 (en) * 2011-05-26 2012-11-29 Pepose Jay Device and method for administering eye medications
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
CA2858161C (en) 2011-12-05 2020-03-10 Incept, Llc Medical organogel processes and compositions
EP2968613B1 (de) 2013-03-11 2019-09-11 University of Florida Research Foundation, Inc. Freisetzung von card-protein zur behandlung von augenentzündungen
CA3121759C (en) 2013-05-03 2024-01-02 Clearside Biomedical, Inc. Apparatus and methods for ocular injection
ITVE20130043A1 (it) * 2013-07-31 2015-02-01 I A C E R S R L Dispositivo perfezionato oftalmologico per il trattamento di malattie corneali quali il cheratocono.
ES2672327T3 (es) * 2014-01-27 2018-06-13 Opia Technologies Dispositivo de iontoforesis ocular
JP5828535B1 (ja) * 2014-10-10 2015-12-09 石根 三井 矯正角膜クロスリンキング用コンタクトレンズ
CN104353183B (zh) * 2014-10-31 2016-12-07 厦门微科格瑞生物科技有限公司 电解液位置固定的可佩戴智能药物导入结构
MX2017009193A (es) 2015-01-22 2017-12-12 Eyegate Pharmaceuticals Inc Lente de contacto iontoforetica.
US10206814B2 (en) * 2016-01-06 2019-02-19 David R. Hardten System and method for the delivery of medications or fluids to the eye
WO2017192565A1 (en) 2016-05-02 2017-11-09 Clearside Biomedical, Inc. Systems and methods for ocular drug delivery
JP2020513983A (ja) 2017-03-23 2020-05-21 ドヘニー アイ インスティテュート 光干渉断層撮影の多重ｅｎ−ｆａｃｅ血管造影平均化システム、方法および装置
US11338139B2 (en) 2018-10-01 2022-05-24 Biovisics Medical, Inc. System and methods for controlled electrical modulation for vision therapy
EP3886974A2 (de) 2018-11-30 2021-10-06 Biovisics Medical, Inc. Kopfgetragene vorrichtungen für die sichttherapie
JP7465271B2 (ja) 2019-01-09 2024-04-10 トゥウェンティ トゥウェンティ セラピューティクス エルエルシー 治療剤放出のための眼球装着装置
US11464674B2 (en) 2019-01-09 2022-10-11 Twenty Twenty Therapeutics Llc Programmable therapeutic agent delivery from eye mounted device
WO2020210471A1 (en) 2019-04-10 2020-10-15 Biovisics Medical, Inc. Systems and interfaces for ocular therapy
WO2020252278A1 (en) 2019-06-14 2020-12-17 Biovisics Medical, Inc. Wearable medical device
CN110547907A (zh) * 2019-08-15 2019-12-10 中南大学湘雅二医院 一种用于眼内手术的双环虹膜扩张器
WO2024009535A1 (ja) * 2022-07-08 2024-01-11 テルモ株式会社 眼内薬物投与装置、薬剤リザーバ及び眼内薬物投与装置の動作方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US551880A (en) * 1895-12-24 Theodore b
US2525381A (en) * 1947-09-25 1950-10-10 Tower Paul Contact-type electrode holder
US3122137A (en) * 1961-10-30 1964-02-25 Erlanger Gustav Device for facilitating iontophoresis treatment of eyes
SU995783A1 (ru) 1980-07-21 1983-02-15 Омский Государственный Ордена Трудового Красного Знамени Медицинский Институт Им.М.И.Калинина Устройство дл электрофореза лекарственных веществ в ткани глаза
US4678466A (en) * 1981-06-25 1987-07-07 Rosenwald Peter L Internal medication delivery method and vehicle
US4564016A (en) 1982-05-24 1986-01-14 The Board Of Trustees Of The Leland Stanford Junior University Apparatus for introducing ionized drugs into the posterior segment of the eye and method
US5053000A (en) * 1985-11-13 1991-10-01 Imperial Chemical Industries Plc Ocular treatment
IL86076A (en) * 1988-04-14 1992-12-01 Inventor S Funding Corp Ltd Transdermal drug delivery device
US4955378A (en) * 1988-05-02 1990-09-11 University Of South Florida Apparatus and methods for performing electrofusion at specific anatomical sites
EP0464138A1 (de) * 1989-03-17 1992-01-08 Candela Laser Corporation Lasertherapiestrahlgerät für glaukombehandlung
US5174304A (en) * 1990-02-16 1992-12-29 Latina Mark A Electrocycloablation apparatus and method
US5472436A (en) * 1994-07-26 1995-12-05 Fremstad; Daria A. Ocular appliance for delivering medication
US5522864A (en) * 1994-10-25 1996-06-04 Wallace; Larry B. Apparatus and method for ocular treatment
AUPM982694A0 (en) * 1994-12-02 1995-01-05 University Of Queensland, The Iontophoresis method and apparatus
US5676648A (en) * 1996-05-08 1997-10-14 The Aps Organization, Llp Iontophoretic drug delivery apparatus and method for use

Also Published As

Publication number Publication date
ATE292493T1 (de) 2005-04-15
BR9900009A (pt) 2001-03-20
CA2257749A1 (en) 1999-07-05
KR19990066875A (ko) 1999-08-16
ATE437672T1 (de) 2009-08-15
CA2257749C (en) 2009-03-24
IL127711A (en) 2004-06-20
ES2236880T3 (es) 2005-07-16
IL127711A0 (en) 1999-10-28
JPH11244323A (ja) 1999-09-14
DE69841028D1 (de) 2009-09-10
EP1452203A2 (de) 2004-09-01
DE69829637T2 (de) 2006-03-09
US6154671A (en) 2000-11-28
FR2773320B1 (fr) 2000-03-03
EP0927560B1 (de) 2005-04-06
EP1452203A3 (de) 2004-09-08
ES2327636T3 (es) 2009-11-02
FR2773320A1 (fr) 1999-07-09
JP4308353B2 (ja) 2009-08-05
EP1452203B1 (de) 2009-07-29
DE69829637D1 (de) 2005-05-12
KR100551706B1 (ko) 2006-07-06
EP0927560A1 (de) 1999-07-07
PT927560E (pt) 2005-07-29

Similar Documents

Publication Publication Date Title
DK0927560T3 (da) Indretning til intraokulær overförsel af aktive produkter ved iontophorese
US10967173B2 (en) Nasal stimulation devices and methods for treating dry eye
US6101411A (en) Dilation enhancer
DK1239774T3 (da) Apparat til behandling af öjensygdomme
WO2003039622A3 (en) Novel iontophoretic drug delivery systems
ATE137658T1 (de) Vorrichtung zur behandlung von augen
ES2509500T9 (es) Dispositivo de retina artificial
US6083250A (en) Apparatus and method for inhibiting lesion formation by selectively treating the prodromal stage of the lesion with a pulsatile electrical stimulation
CN206515567U (zh) 一种载药性角膜接触镜
DK0403360T3 (da) Anvendelse af phenylethanolaminer til fremstilling af et lægemiddel mod øjenlidelser
SU942744A1 (ru) Устройство дл электрофореза лекарственных веществ в ткани глаза
AU2017204782B2 (en) Nasal stimulation devices and methods
Sukhomlinova et al. Normal Physiology. Module 1
DK0453337T3 (da) Anvendelse af hexetidin eller derivater eller salte deraf til fremstilling af et farmaceutisk præparat til oftalmologisk anvendelse
Novello et al. An ethnological approach to self-injurious behavior
RU93009013A (ru) Способ вызывания содружественного зрачкового рефлекса на свет
RU94022801A (ru) Способ имплантации искусственного хрусталика глаза при отсутствии капсулы хрусталика
BG60887B1 (en) Thienethiopyran sulphonamide derivatives and their application in ophthalmological preparations
UA19588A (uk) Спосіб екстракції травматичhої катаракти з пошкоджеhhям задhьої капсули кришталика